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김지원,정희경,이주영,김광휘,김태연,이태걸,김동은,Kim, Ji-Won,Jeong, Hu-Gyeong,Lee, Joo-Young,Kim, Kwang-Hwi,Kim, Tae-Yeon,Lee, Tae-Geol,Kim, Dong-Eun 대한한방안이비인후피부과학회 2017 한방안이비인후피부과학회지 Vol.30 No.4
Objectives : The purpose of this study is to investigate recent clinical studies on the effect of acupuncture on hearing loss. Methods : Based on the PubMed search with the key search terms of 'hearing loss, acupuncture', dated from 2004 to 2017, 1 controlled trials, 3 case reports and 3 case series was found, and were analyzed for this study. Results : 1. The most commonly used acupoints were Shuaigu(GB8) and Fengchi(GB20). 2. The most commonly used meridians were the du channel, the gall bladder meridian of foot-shaoyang, and the triple bunner meridian of hand shaoyang. 3. Acupuncture treatment was effective for conductive and sensorineural hearing loss, especially sudden sensory neural hearing loss. 4. More clinical studies are needed to prove the effectiveness of the acupuncture on hearing loss. To be more objective on the study results, we can measure auditory brainstem response for hearing loss after acupuncture treatment.
김지원,정홍영,김효희,권유리,엄광문,이정환,김경섭,전재훈,박병규,Kim, Ji-Won,Jeong, Hong-Young,Kim, Hyo-Hee,Kwon, Yu-Ri,Eom, Gwang-Moon,Lee, Jeong-Whan,Kim, Kyung-Seoup,Jun, Jae-Hoon,Park, Byung Kyu 대한의용생체공학회 2012 의공학회지 Vol.33 No.4
Elderly women are reported to have greater risk of falls. The purpose of this paper was to investigate the possible gender differences in the reaction performance of ankle joint muscles, which have dominant role in the control of sagittal plane balance. Twenty-six elderly men and women with comparable mean age participated in this study. Reaction times to the audible beeps were measured in the tibialis anterior muscle and gastrocnemius muscle. Reaction time variables included premotor time, electromechanical delay and total reaction time. Gender difference in each reaction time was investigated by independent t-test. In both muscles, premotor time was longer in men but the electromechanical delay was longer in women (p < 0.05). Resulting total reaction time was longer in men in tibialis anterior muscle (p < 0.01) and it tended to be longer in men also in gastrocnemius muscle (p = 0.25). The results demonstrates that the overall reaction performances of elderly women is better than or comparable to those of elderly men in ankle joint muscles. This suggests that the reaction performance of ankle muscles is hardly the cause of the greater risk of falls in elderly women.
한국인에서 조현병과 Cannabinoid Receptor 1 유전자의 삼핵산 반복서열의 연합에 대한 연구
김지원,노양호,김민재,김채리,박병래,배준설,신형두,최인근,한상우,황재욱,우성일,Kim, Ji-Won,Roh, Yang-Ho,Kim, Min-Jea,Kim, Chea-Ri,Park, Byung-Lae,Bae, Joon Seol,Shin, Hyoung Doo,Choi, Ihn-Geun,Han, Sang-Woo,Hwang, Jaeuk,Woo, Sung-Il 대한생물정신의학회 2014 생물정신의학 Vol.21 No.3
Objectives Previous studies suggest that the cannabinoid receptor 1 (CNR1) gene could be an important candidate gene for schizophrenia. According to linkage studies, this gene is located on chromosome 6q14-q15, which is known to harbor the schizophrenia susceptibility locus (locus 5, SCZ5, OMIM 803175). The pharmacological agent delta-9-tetrahydrocannabinol (${\Delta}$-9-THC) seems to elicit the symptoms of schizophrenia. The association between CNR1 polymorphisms and schizophrenia is actively being investigated, and some studies have linked the AAT-trinucleotide repeats in CNR1 to the onset of schizophrenia. In this study, we have investigated the association between the AAT-trinucleotide repeats in CNR1 and schizophrenia by studying schizophrenia patients and healthy individuals from Korea. Methods DNA was extracted from the blood samples of 394 control subjects and 337 patients diagnosed with schizophrenia (as per the Diagnostic and Statistical Manual of Mental Disorders, fourth edition criteria). After polymerase chain reaction amplification, a logistic regression analysis, with age and gender as the covariates, was performed to study the variations in the AAT-repeat polymorphisms between the two groups. Results In total, 8 types of trinucleotide repeats were identified, each containing 7, 8, 10, 11, 12, 13, 14, and 15 repeats, respectively. $(AAT)_{13}$ allele was most frequently observed, with a frequency of 33.6% and 31.6% in the patient and control groups, respectively. The frequency of the other repeat alleles in the patient group (in the decreasing order) was as follows : $(AAT)_{13}$ 33.6%, $(AAT)_{14}$ 21.6%, $(AAT)_{12}$ 18.5%, and $(AAT)_{7}$ 11.1%. The frequency of the repeat alleles in the control group (in the decreasing order) was as follows : $(AAT)_{13}$ 31.6%, $(AAT)_{14}$ 24.5%, $(AAT)_{12}$ 17.2%, and $(AAT)_{7}$ 11.6%. However, there were no significant differences in the AAT-repeat polymorphisms of the CNR1 gene between the patient group and the control group. Conclusions Although our study revealed no significant association of the AAT-repeat polymorphism of the CNR1 gene with schizophrenia, it will serve as a good reference for future studies designed to examine the cannabinoid hypothesis of schizophrenia.
김지원,Kim, Ji-Won 대한출판문화협회 1999 출판저널 Vol.254 No.-
조각가의 꿈을 지녔던 소년 김원이 집안형편을 고려해 공과대학에서 건축을 공부한 것은 결과적으로 잘된 일이다. 대학 졸업 후 동기들은 미국 유학길에 올랐지만 그는 김수근 건축사무실에서 밤샘으로 현장을 지켰다. 스물아홉에 떠난 네덜란드 유학은 그 자체 문화적 충격이었고, 여행으로 건축문화예술의 실물을 접하는 기회였다. 돌아와 30여년간 명동 쌩뽈 수도원, 국립국악당, 광주 가톨릭대학교 등 2백여 건축물을 완성시킨 그의 일관된 건축관은 보편성이다. 우리나라의 그 상식적이지 않은 건축문화에 대해 숱한 분노의 발언을 쏟아낸 것도 그의 건축관을 실천하는 또다른 모습이다.
김지원,Kim, Ji-Won 대한출판문화협회 1998 출판저널 Vol.238 No.-
서울출판인포럼은 지난 10일 서울 조선호텔에서 가진 조찬모임에 이해찬 교육부 장관을 초청, '교육과 출판' 을 둘러싼 광범위한 의견을 나눴다. 이장관은 교육부가 초.중.고 권장도서목록을 올해 안에 선정할 수 있도록 30명으로 이뤄진 '새로운공동체추진위원회'(가칭)를 이달 25일까지 발족시키고, 이를 강력히 실천할 수 있도록 지역단위의 '새교육공동체 시민모임'의 정착에 간접지원하겠으며, 독서가 학교 교과과정의 한 형태로 자리잡을 수 있도록 제도화하겠다고 밝혔다. 교육의 입장에서 바라본 이장관의 독서와 출판에 대한 시각과 함께 출판인과 나눈 대화 내용을 정리해 싣는다.