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김준범,문찬식,장윤희,유호민,이종복,Jun Bum Kim,M,D,Chan Shik Moon,M,D,Yoon Hee Chang,M,D,Ho Min Lew,M,D,Jong Bok Lee,M,D 대한안과학회 2007 대한안과학회지 Vol.48 No.3
Purpose: To study the characteristics of the accompanying amblyopia and strabismus in patients with anisometropia. Methods: We retrospectively reviewed the medical records of 193 patients, who had either spherical or cylindrical anisometropia of more than 1.00D. Patients were divided into four groups: spherical hyperopic anisometropia, spherical myopic anisometropia, cylindrical hyperopic anisometropia, and cylindrical myopic anisometropia. We investigated the accompanying amblyopia and strabismus. Amblyopia was treated with lens correction and patch therapy and we analyzed the results for 78 patients who fulfilled six-month follow-up examinations. Results: There was no significant difference in the frequency of amblyopia between spherical and cylindrical anisometropia. Spherical myopic anisometropia of more than 3.00D showed a significant increase in the incidence of amblyopia (p=0.001). Spherical hyperopic anisometropia of more than 1.00D, cylindrical hyperopic anisometropia of more than 2.00D, and cylindrical myopic anisometropia of more than 2.00D showed an increased tendency for amblyopia. Between spherical and cylindrical anisometropia, there were no significant differences in the results and duration of amblyopia treatment, and type and frequency of strabismus. Conclusions: In spherical anisometropia, hyperopic anisometropia has a higher risk for developing amblyopia. We could find the threshold for the development of amblyopia.
The Genotype and Clinical Phenotype of Korean Patients with Familial Hypokalemic Periodic Paralysis
김준범,Man Ho Kim,Soon Ju Lee,김대중,Byung Churl Lee 대한의학회 2007 Journal of Korean medical science Vol.22 No.6
Familial hypokalemic periodic paralysis (HOPP) is a rare autosomal-dominant disease characterized by reversible attacks of muscle weakness occurring with episodic hypokalemia. Mutations in the skeletal muscle calcium (CACNA1S) and sodium channel (SCN4A) genes have been reported to be responsible for familial HOPP. Fifty-one HOPP patients from 20 Korean families were studied to determine the relative frequency of the known mutations and to specify the clinical features associated with the identified mutations. DNA analysis identified known mutations in 12 families: 9 (75%) were linked to the CACNA1S gene and 3 (25%) to the SCN4A gene. The Arg528His mutation in the CACNA1S gene was found to be predominant in these 12 families. Additionally, we have detected one novel silent exonic mutation (1950C>T) in the SCN4A gene. As for a SCN4A Arg669His mutation, incomplete penetrance in a woman was observed. Characteristic clinical features were observed both in patients with and without mutations. This study presents comprehensive data on the genotype and phenotype of Korean families with HOPP.
전족부에 발생한 색소 융모 결절성 활액막염 (1례 보고)
김준범,송인수,전재균,김태인,선동혁,이경태,Kim, Jun Beom,Song, In Soo,Chon, Je Gyun,Kim, Tae In,Sun, Dong Hyuk,Lee, Kyung Tai 대한족부족관절학회 2013 대한족부족관절학회지 Vol.17 No.1
Pigmented villonodular synovitis (PVNS) is a slowly, progressive, proliferative disorder of synovial tissue characterized by villous or nodular changes of synovial-lined joints, bursae, and tendon sheaths and most frequently affects the large joints, with the knee and hip. A few studies have been reported that occurred PVNS in small joint, but mainly in hands. It is a very rare condition that occurs in the small joints of the forefoot. We have experienced the case, which developed in small joint of the forefoot, and performed total synovectomy. After the operation, there was no recurrence. We report a case of PVNS in forefoot with a review of the literature.
김준범,양근모,최준수,Kim, Jun-Beom,Yang, Geun-Mo,Choi, Joon-Soo 한국잔디학회 2008 한국잔디학회지 Vol.22 No.2
본 연구는 해안가 매립지인 간척지에서 염분이 포함된 물을 관수하면서 크리핑 벤트그래스 품종을 평가해해 보고자 수행되었다. 국내에서 수입되고 있는 크리핑 벤트그래스 10종을 공시하여 간척지에 다층구조의 그린을 조성 후 생육을 평가하였다. 사용된 관수용수의 전기전도도(ECw)는 $0.28-3.3\;d\;S{\cdot}m^{-1}$의 범위였다. 관행적인 관리하에서 잔디의 엽색, 품질, 피복률, 밀도, 생육량 등을 조사하였다. 엽색은 진녹색, 녹색, 연녹색 등의 색상으로 나타났으며, T-1, Pennlinks, Crenshaw 등이 진한 녹색을 띠었으며, Penn A1, declaration 품종이 연한 녹색을 띄었다. 가시적 품질은 조사시기에 따라 편차가 있었으며, 평균적으로 Penn A1, Penn A3, L-93 등이 높은 품질을 보였다. 파종 11주 후 피복률 조사시 평균 75.3%의 피복률을 나타냈으며, Dominant, L-93, Penn A1 등이 각각 80, 80, 78.3%로 높게 조사되었다. 조성 1년차에는 가시적 밀도 차이가 관찰되지 않았으나 2년차부터는 품종간에 밀도 차이가 관찰되었다. 조성 2년 후 조사시 밀도가 높은 초종은 Declaration, Penn A1, T-1, L-93 순으로 나타났다. 상기 조사결과 크리핑 벤트그래스는 염이 포함된 관수용수 하에서도 양호한 생육을 보였으며, 품종간에 품질 및 밀도 등에서 차이를 보인 것으로 조사되었다. 본 연구 자료는 간척지에 건설되고 있는 골프장에서 크리핑 벤트그래스 품종을 선발하는데 필요한 기초자료로 활용할 수 있을 것이다. This study was carried out to examine the growth performance of 10 cultivars of creeping bentgrass under salt injury in Seo-san reclaimed area. Turfgrass performance studies included 10 creeping bentgrass cultivars (T-1, L-93, Penn A1, Pennlinks II, Seaside II, Declaration, Penn A4, Crenshaw, Dominant, and Penncross). Ten creeping bentgrass cultivars were grown on a USGA recommended research green. Plots were seeded on May 31, 2006 at the rate of $7\;g{\cdot}m^{-1}$. Electric conductivities of irrigation water (ECw) and soil (ECe) were ranged from 0.28 to $3.3\;d\;S{\cdot}m^{-1}$ and from 0.25 to $3.5\;d\;S{\cdot}m^{-1}$ respectively. Leaf color, turf quality, coverage rate, and growth rate were checked under the salty condition in reclaimed land for 2 year. Creeping bentgrass cultivars of T-1, Penn links, and Crenshaw presented dark green color and Penn A1, Declaration showed lighter green color. Penn A1, Penn A4 and L-93 exhibited the highest overall turfgrass quality. Average visual coverage was 75.3% after eleven weeks after seeding. Dominant, L-93, and Penn A1 resulted in higher visual coverage compared to the other cultivars. There was no difference in density among cultivars at 1 year after establishment. However, Declaration, Penn A1, T-1, and L-93 showed higher density compared to the other cultivars at 2 years after seeding. Creeping bentgrass showed different quality, density and color in salty soil (ECe: $0.25-3.5\;d\;S{\cdot}m^{-1}$) and from application of salty irrigation water (ECw: $0.28-3.3\;d\;S{\cdot}m^{-1}$) conditions. These results will be useful where selecting green cultivars for the golf courses in reclaimed land area.