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박성태,이정구,김제종,조재흥,Park, Sung-Tae,Lee, Jeong-Gu,Kim, Je-Jong,Cho, Jae-Heug 대한생식의학회 1996 Clinical and Experimental Reproductive Medicine Vol.23 No.1
Vasectomy has become a popular method for male sterilization and this, in tum, has been followed by an increase in the number of patients requiring vasectomy reversal. Recently, many authors have reported a high success rate of vasovasostomy using microsurgical techniques. However, a significant discrepancy exist between the anatomical patency rate and pregnancy rate despite improvements in surgical techniques. Number of 420 patients who underwent vasovasostomy by a modified one layer reanastomosis from January 1986 to December 1994 were reviewed. Of the total, Complete follow up were possible in 115 patients. Of the 115 patients, 74 patients were treated by macroscopic reanastomosis, and microscopic technique were applied in 41 patients. Duration of vasal obstruction, gross apperance of vasal fluid, operative method, presence or absence of sperm and sperm granuloma, and results of postoperative semen analysis were analyzed as factors influencing the pregnancy rate. Success rates for patency and for pregnancy were 81% and, 42% respectively. Rate of pregnancy were increased if there were shorter periods of obstruction(<10years), bilateral observation of watery vasal fluid, presence of sperm bilaterally, bilateral presence of sperm granuloma at the vasectomy site, and normal results on postoperative semenalysis. With these results, we can conclude that all factors mentioned may affect the success rate of pregnancy following vasovasostomy.
유지,이정구,김제종,고성건,Yoo, Ji,Lee, Jeong-Gu,Kim, Je-Jong,Koh, Sung-Kun 대한생식의학회 1991 Clinical and Experimental Reproductive Medicine Vol.18 No.2
A total of 167 patients underwent mascroscopic vasovasostomy by a modified double layer reanastomosis to correct postvasectomy sterility during a 5-year period between 1986 and 1991. We obtained the anatomical patency and pregnancy rates from 61 patients whose follow-ups were completed. There by, we report the following results. 1. Of the 167 patients, the mean age and the average duration of vasobstruction were 34.0 and 4. 4 years respectively. The reasons for ecanalization were desire for more baby in 71.9%. death of children, 24.5% and remarriage in 3.6%. 2. Of the 61 patients with complete follow-up. the anatomical patency and pregnancy rates were 83.6%(51 patients) and 50.8%(31 patients) respectively. 3. For the 36 out of 61 patients whose duration of vasobstruction was less than 5 years, the anatomical patency and pregnancy rates were 88.9%(32 patients) and 58.3%(21 patients) respectively. The rates for the remaining 25 patients whose duration was greater than 5 years were 80.0%(20 patients) and 40.0%(10 patients). 4. Of the 61 patients, 51 exhibited sperms from the proximal vas on microscope during the operation. Their anatomical patency and pregnancy rates were 88.2%(45) and 54.9%(28) respectively. The rates for the remaining 10 patients without any sperms were 60.0%(6) and 30.0%(3). From the above results, we can conclude that macroscopic reanastomoses by modified double layer technique has appreciable success rates that could possibly be compared to the microscopic results.
심인성 발기부전 환자에서 Norepinephrine과 Serotonin에 관한 연구
김진세,유승호,문두건,김제종,정인과,Kim, Jin Se,Ryu, Seung Ho,Moon, Du Geon,Kim, Je Jong,Jung, In Kwa 대한생물정신의학회 1998 생물정신의학 Vol.5 No.2
Various neurotransmitters have been proposed as possible mediators of penile erection. Especially, norepinephrine and serotonin might have a important role in sexual arousal and penile erection. And it could be hypothesized that the psychogenic impotence is associated with the depletion or imbalance of norepinephrine and serotonin from evidences, such as the symptomatic manifestation of depression and the antidepressantinduced sexual dysfunction. The authors investigates the association of norepienphrine and serotonin with psychogenic impotence. The psychogenic impotent group(PIG) consisted of twenty-three patients with psychogenic impotence and the controlled group(CG) consisted of twenty-seven patients without psychogenic impotence. PIG had no organic cause accounting for their erectile dysfunction. The Beck Depression Inventory(BDI) and the State-Trait Anxiety Inventory(STAI) were applied to each subject to assess mood, state anxiety(SA) and trait anxiety(TA). Plasma norepinephrine level from systemic blood and 5-hydroxyindoleacetic acid(HIAA) levels from 24-hours urine were measured in each subject. The mean score of BDI of PIG was significantly higher than that of CG(p=0.015). PIG had a tendency of higher TA compared with CG(p=0.054). And also SA was higher in PIG, but did not show significant difference(p=0.193). The level of norepinephrine was significantly lower in patient with psychogenic impotence(p=0.000). And the level of 24-hours urine 5-HIAA was lower in PIG but did not show significant difference(p=0.494). Although the authors did not exclude depressive disorders in PIG, the present findings suggest that psychogenic impotence might have higher depressive mood and trait anxiety, and be associated with the depletion of norepinephrine in systemic blood.
요로감염증에 대한 Lomefloxacine의 임상 경험
김제종,고성건,이수철 대한감염학회 1992 감염 Vol.24 No.1
Lomefloxacine (SC-47111, NY-198), a new synthetic difluorinated quinolone for oral use with broad spectum antimicrobial activity, was administered in the treatment of 38 patients with urinary tract infection (uncomplicated 27, complicated 11). 154 cases of urine cultures including those of 38 patients treated by lomefloxacine were performed during the synchronous period. We reviewed the bacterio-logical, clinical effectiveness ans side effects of Lomefloxacine. The following results were obtained. 1) Among the 154 urine cultures with the growth of microorganism, 131 were sensitive to Lomefloxacine (overall sensitive rate; 85%) but the sensitive rates in Pseudomonas aeruginosa and Stereptococcus group D were 63% and 47% respectively. 2) In 27 uncomplicted urinary tract infection (UTI), 26 patients were cured and 1 patient was improved clinically in 5~9 days post treatment period. In 11 complicated UTI, 2 and 9 showed cure and improvement respectively. 3) In 39 isolated causative microorganism (E. coli 30, Staphylococcus epidermidis 2, E. aerogenes 2, Staphylococcus group D 2, Pseudomonas aeruginosa 1, Morganella morganii 1, Proteus mirabilis 1), the total of 39 cases were eradicated. 4) There were not any significant side effects that required discontinuation of lomefloxacine during the treatment. from the above results, lomefloxacine was considered to be a useful new oral antibiotic in the treatment of UTI without any significant side effects.