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독시라민 과다복용에 의한 횡문근 용해 및 급성 신부전 2례
정재권,김성호,김인식,김선웅,주동욱,이덕현,김종근,Jung Jae Kwon,Kim Sung Ho,Kim In Seek,Kim Seon Woong,Ju Dong Wook,Lee Duk Hyun,Kim Jong Kun 대한임상독성학회 2004 대한임상독성학회지 Vol.2 No.1
Doxylamine succinate is an antihistamine used primarily as a sleep-induction. It can be gotten without a doctor's prescription in Korea, so it' s overdoses were frequently encountered. There were several reports that the overdoses of doxylamine might cause rhabdomyolysis, but few cases have been reported that it is related to acute renal failure (ARF). In cases that ARF occur, most of them are not severe enough to require hemodialysis. We experienced two cases of severe rhabdomyolysis complicating ARF after doxylamine overdose and treated with hemodialysis. Clinicians should be aware of the potentially lethal complications of rhabdomyolysis in patients who ingest doxylamine succinate and the needs for prompt intervention and careful assessment of renal function.
독시라민 과다복용에 의한 횡문근 융해 및 급성 신부전 2례
정재권 ( Jae Kwon Jung ),김성호 ( Sung Ho Kim ),김인식 ( In Seek Kim ),김선웅 ( Seon Woong Kim ),주동욱 ( Dong Wook Ju ),이덕현 ( Duk Hyun Lee ),김종근 ( Jong Kun Kim ) 대한임상독성학회 2004 대한임상독성학회지 Vol.2 No.1
Doxylamine succinate is an antihistamine used primarily as a sleep-induction. It can be gotten without a doctor’s prescription in Korea, so it’s overdoses were frequently encountered. There were several reports that the overdoses of doxylamine might cause rhabdomyolysis, but few cases have been reported that it is related to acute renal failure (ARF). In cases that ARF occur, most of them are not severe enough to require hemodialysis. We experienced two cases of severe rhabdomyolysis complicating ARF after doxylamine overdose and treated with hemodialysis. Clinicians should be aware of the potentially lethal complications of rhabdomyolysis in patients who ingest doxylamine succinate and the needs for prompt intervention and careful assessment of renal function.
윤혜진,노태묵,김선웅,박동희,김인식,김연재,이병기,박지연,정진홍 영남대학교 의과대학 2003 Yeungnam University Journal of Medicine Vol.20 No.1
일측성 폐동맥 형성부전증은 대동맥궁의 발생과정상의 이상으로 인해 대부분 선천성 심질환과 동반되어 나타나며, 일부에서 단독으로 발생한다. 흉부 전산화단층촬영, 자기공명영상과 같은 비침습적인 검사로 확진이 가능하며, 동반질환이 없는 일측성 폐동맥 형성부전증은 대게 치료가 필요없다. 자자들은 반복되는 객혈을 주소로 내원한 젊은 여자에서 객혈의 원인규명 과정에서 진단된 좌폐동맥 형성부전증 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Unilateral absence of a pulmonary artery (UAPA) is a rare congenital anomaly that is frequently associated with other cardiovascular anomalies first reported by Fraentzel in 1968. Most patients who have no associated cardiac anomalies have only minor or absent symptoms. We experienced a case of isolated UAPA in a young female presenting hemoptysis. The chest radiograph showed a small left lung volume and high resolutional CT of chest showed multiple subpleural nodules and centrilobular nodules in parenchyma. The video-assisted thoracoscopic biopsy revealed diffuse dilated vessels in visceral pleura. The pulmonary angiogram confirmed the absence of the left main pulmonary artery.