RISS 학술연구정보서비스

검색
다국어 입력

http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.

변환된 중국어를 복사하여 사용하시면 됩니다.

예시)
  • 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
  • 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
닫기
    인기검색어 순위 펼치기

    RISS 인기검색어

      검색결과 좁혀 보기

      선택해제
      • 좁혀본 항목 보기순서

        • 원문유무
        • 원문제공처
          펼치기
        • 등재정보
          펼치기
        • 학술지명
          펼치기
        • 주제분류
          펼치기
        • 발행연도
          펼치기
        • 작성언어
        • 저자
          펼치기

      오늘 본 자료

      • 오늘 본 자료가 없습니다.
      더보기
      • 무료
      • 기관 내 무료
      • 유료
      • KCI등재

        곤충 면역반응을 중개하는 프로스타글란딘의 분자적 기작과 해충방제 응용

        김용균 한국응용곤충학회 2022 한국응용곤충학회지 Vol.61 No.1

        Like vertebrates, insects synthesize various eicosanoids after the committed catalytic step of phospholipase A 2 (PLA 2 ). However, the subsequent biosynthetic steps exhibit some deviation from those of vertebrates. Due to little composition of arachidonic acid in insect phospholipids, PLA 2 releases linoleic acid, which is another polyunsaturated fatty acid and relatively rich in insect phospholipids, to synthesize arachidonic acid via chain extension and desaturation. Resulting arachidonic acid is then oxygenated into a prostaglandin (PG), PGH 2 , by a specific peroxidase called peroxynectin, but not by cyclooxygenase. PGH 2 is then isomerized to various PGs such as PGA 2 , PGD 2 , PGE 2 , PGI 2 , and a thromboxane (TXB 2 ). All four epoxyeicosatrienoic acids such as 5,6-EET, 8,9-EET, 11,12-EET, and 14,15-EET are also synthesized from arachidonic acid by oxygenation of vertebrate types of monooxygenases. However, the other type of eicosanoids called leukotrienes are found in insect tissues but their synthetic pathway is unclear. Eicosanoids mediate various insect physiological processes such as metabolism, excretion, immunity, and reproduction. Thus, identification of novel compounds interrupting eicosanoid biosynthesis would be a novel approach to develop insecticides. This review focuses on PGs and their immune mediation. 척추동물과 유사하게 곤충도 인지질분해효소(phospholipase A 2 )의 촉매 작용으로 다양한 아이코사노이드를 합성한다. 그러나 일련의 아이코사노이드 생합성과정은 척추동물과 차이를 보이는데, 이는 곤충의 인지질에는 전구물질인 아라키도닉산의 함량이 낮기 때문이다. 대신에 비교적 풍부하게 존재하는 다가불포화지방산인 리놀레익산을 기반으로 사슬 연장 및 불포화반응으로 아라키도닉산을 합성하여 척추동물과 같이 아이코사노이드 전구물질로 이용하는 것 같다. 이렇게 해서 형성된 아라키도닉산은 다시 척추동물의 cyclooxygenase와 유사한 peroxynectin이PGH 2 형태의 프로스타글란딘(prostaglandin: PG) 전구물질을 형성하게 된다. 이후 여러 이성체 효소들의 특이적 반응에 의해 PGA 2 , PGD 2 , PGE 2 , PGI 2 , TXB 2 의 다양한 PG가 생성된다. 반면에 또 다른 형태의 아이코사노이드인 에폭시아이코사트리에노익산(epoxyeicosatrienoic acid: EET)은 척추동물과 유사한 단일산화효소의 산화반응으로 아라키도닉산을 전구물질로 5,6-EET, 8,9-EET, 11,12-EET, 14,15-EET를형성하게 된다. 그러나 세 번째 아이코사노이드 부류인 류코트리엔(leukotriene)의 경우 곤충 체내 존재는 확인되었지만 생합성 과정은 아직 밝혀지지 않았다. 이들 아이코사노이드가 곤충의 대사, 배설, 면역 및 생식에 관여하는 생리작용을 중개한다. 따라서 아이코사노이드 생합성 과정을 교란하는 물질 탐색은 새로운 살충제 개발 전략이 된다. 본 종설은 이 가운데 PG의 곤충 면역 중개 기작을 소개한다.

      • KCI등재후보

        에도어(江語)명령표현 「しやれ」의 어미 변화에 관한 고찰

        김용균 고려대학교 일본연구센터 2009 일본연구 Vol.12 No.-

        '스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 9시까지 원문보기가 가능합니다.

        本稿では、日本語の史の中でも特に消滅という点に注目して近世に焦点をてて、近世日本語までには用いられたが現代日本語では見られなくなった江語の敬語命令表現「しやれ」→「しやい」の語尾化について、全的傾向と完了時期を中心にして考察してみた。特に明和~享和期の江語資料39種(江落本類31種、江本類4種、表紙類4種)の語尾化の態の分析結果に基づいて、上方語と敬語命令表現「なされ」→「なさい」の語尾化の全的傾向及び完了時期と比較しながら時期、資料、位相、地域による速差とその原因について討してみた。その結果、幾つかの特的事が明からにされたかのように思う。まず、語尾化の全的傾向としては、①明和期と安政期間における「しやれ」→「しやい」の語尾化の速差が見られる。②江語資料の部間による速差が認められて、江落本類の「しやれ」→「しやい」の語尾化は江本類及び表紙類の語尾化よりはやい。③位相的な面から見ると、男性語と女性語間による「しやれ」→「しやい」の語尾化の速差は見られない。④地域的な面から見ると、江語の「しやれ」→「しやい」の語尾化は上方語の語尾化よりはやい、という事が指摘できた。一方、語尾化の完了時期としては、⑤口頭語、つまり話文における「しやれ」→「しやい」の語尾化の完了時期は「なされ」→「なさい」の語尾化の完了時期である明和期までよりい安永期と推定される、という事が指摘できた。特に、このような事の中で②③④は「なされ」→「なさい」の語尾化の傾向と大一致すると言えようが、①は傾向を異にすると思われる。なお、⑤も「なされ」→「なさい」の語尾化の完了時期と異なるという点から注目される。

      • KCI등재

        Discrimination of different generations of Zeugodacus scutellata using age grading technique and their local genetic variation

        김용균,Md. Abdullah Al Baki,권기면,김동순,박계청,안정준 한국응용곤충학회 2019 Journal of Asia-Pacific Entomology Vol.22 No.3

        The striped fruit fly, Zeugodacus scutellata, exhibits generation overlap due to its relatively long lifespan. This study clarified the fly generations by age-grading technique and traced migration of local populations using genetic markers. Male adults were monitored using Cue-lure in two different places (Andong and Guri) of mainland Korea during the entire host cultivating period. They showed two occurrence peaks (from late July to early August and from mid-August to mid-October). A developmental model of Z. scutellata using rate summation method predicted four generations during this period. Pterin amounts in fly heads increased with adult age and indicated at least 3 cycles of age variation during the occurrence period with an additional adult generation after the third cycle. The additional peak was supported by field monitoring using protein diet supplemented with terpinyl acetate, which showed an additional occurrence peak during October. These seasonal populations were monitored through their migration by gene flow analysis using randomly amplified polymorphic DNA (RAPD) markers. In each locality, three seasonal populations at July, August, and September were discrete. Although local populations were genetically discrete at July, they were not separate at late seasons except for Jeju populations. These results indicate the usefulness of the head pterin quantification in age-grading of adult populations and suggest that Z. scutellata occurs at least four generations a year. In addition, gene flow analysis using RAPD suggests frequent movements among local populations along with season progression.

      • KCI등재

        When It Rains, It Pours: Foreign Direct Investment and Provincial Corruption in Vietnam

        김용균 동아시아연구원 2019 Journal of East Asian Studies Vol.19 No.2

        Does foreign direct investment (FDI) promote or hinder good governance in a host state? In this article, I analyze the effects of FDI on subnational-level corruption across 63 provinces in Vietnam and find that FDI has both promoted and hindered control of corruption. Initially, FDI creates resources and incentives to improve governance and reduce corruption for early winner provinces. Yet, once FDI begins to pour in, different dynamics start to take effect. While the resources and incentives accrued to FDI-recipient provinces become less effective in further curbing corruption as more FDI flows in, FDI provides leaders of those provinces with growing opportunities and increased abilities to seek and pursue rents, leading to a prevalence of corruption. Using both qualitative and quantitative data, I find strong evidence that the control of corruption is weakest at the extremes: in provinces with the least and the most FDI.

      • KCI등재

        농촌주택 평면구성 및 공간사용실태 연구 - 전라남도 장흥군 장평면 우산마을 중심으로 -

        김용균,김상범,안필균,엄성준,조숙영 한국농촌건축학회 2021 농촌건축 : 한국농촌건축학회논문집 Vol.23 No.4

        This study aims to provide necessary, basic data for future space planning of rural housing through a survey on the size of residential space and space utilization of rural housing. To this end, this study analyzed the size and space of rural houses in actual use, and also analyzed the size and characteristics of the essential space for life, which were collected via a survey. In particular, Usan Village in Jangheung, where various types of houses and renewed houses coexist due to continued changes in the form of traditional villages, was selected for a target site of this study. In next step, this study analyzed the current status of use of each house in the village and compared the size of each space and the characteristics of space utilization. The results of the survey on Usan village, on where divergent traditional and modern houses are located, are as follows. First, Usan Village has total 31 traditional and modern houses. Most of the houses have been aging and formed into old-age households, and the expansion, renovation, and construction of farmhouses have progressed. Second, the population of Usan Village has decreased, and the number of residents per household is currently 1.4. Third, the survey indicates that the flat area of rural houses was 80.6㎡, the average area of living space was 54.1㎡, and the average area of water storage space was 26.5㎡, and the main living area was changed to water storage space due to the decrease in the number of household members in rural areas.

      • KCI등재

        Political Institutions and Debt Dynamics in Developing Countries: Centralization of Power is a Double-Edged Sword

        김용균,Daniel C. O'Neill 이화여자대학교 이화사회과학원 2019 사회과학연구논총 Vol.35 No.1

        While international and domestic economic factors influence a government’s willingness and ability both to accrue and to pay off sovereign debt, political institutions also play an important role. We present an analysis of the effects of political institutions on foreign-debt buildup and reduction in developing countries. Our findings show that the degree of centralization of power, whether through presidential systems, unified governments, or the lack of a federal or otherwise decentralized system, is a double-edged sword. On the one hand, governments in such systems are more likely to indulge in debt expanding spending sprees, particularly left leaning governments, during election years, in more democratic states. On the other hand, governments with more centralized power are better able to cut spending and reduce debt, particularly those operating within more authoritarian political institutions. Overall, our findings imply that centralized power in the hands of a national executive in a highly democratic setting is more likely to lead to rapid foreign debt buildup, yet executives in such settings are often unable to take the drastic measures needed to reduce debt in times of imminent crisis. In short, political institutions impact both debt buildup and debt reduction.

      • KCI등재후보

        배관 검사용 Radiometric Scanning System 제작 및 시험

        김용균,홍석붕,정종은,이정기,이윤호,정용하 한국비파괴검사학회 2002 한국비파괴검사학회지 Vol.22 No.5

        필름을 사용하지 않는 방사선투과검사 시스템인 1차원 Radiometric scanning system을 개발하여 부식 및 침적물이 있는 배관의 두께평가에 적용해 보았다. 개발된 시스템은 단일 방사성 동위원소에서 나오는 방사선을 선형으로 접속하여 시험체를 투과시킨 방사선을 한개의 섬광형 검출기인 BGO를 사용하여 검출하는 single source - single detector alignment system을 제어하는 기계주사 시스템과 제어 프로그램을 개발하였다. 개발된 시스템의 성능을 GEANT4 프로그램을 사용하여 예측하여 보았다. 그리고, 인공결함을 제작하여 넣은 시편과 두께 변화를 준 시편에 적용하여 실제 성능을 평가하였다. 이 시스템은 방사성 동위원소를 이용하여 배관의 부식과 침적물에 의한 두께 변화에 대하여 실시간으로 필름을 사용하지 않고 평가할 수 있는 가능성을 알 수 있었다. One dimensional Radiometric scanning was fabricated and tested as a filmless radiographic inspection system, which could be applied to the evaluation of the corrosion and deposits in the pipeline. This system is composed of the single radioactive source of the collimated focusing beam, and single scintillation detector of BGO, and the mechanical scanning system to transport and align the source and detector, and the operating software to automatically control the mechanical scan system. The performance of the system was simulated using GEANT4 software. This system is applied to one specimen having an artificial flaw(flat bottom hole) in the pipe and other specimen with thickness variation. For the inspection by using the radioactive source in the pipeline, it is possible to evaluate the corrosion and deposits in real time and without film.

      • KCI등재

        版本狂言記에 보이는 사역표현의 4단화 경향에 관한 일고찰

        김용균 고려대학교 글로벌일본연구원 2010 일본연구 Vol.14 No.-

        '스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 9시까지 원문보기가 가능합니다.

        な上方語資料である版本狂言記に見られる使役表現の四段化の傾向について考察したものである。特に万治~享保期の版本狂言記4種(狂言記(1660)続狂言記(1700)狂言記外五十番(1700)狂言記拾遺(1730))の四段化の実態の分析結果に基づいて、世話浄瑠璃及び上方絵入狂言本の傾向と比較しながら単語、活用形、文体、時期による遅速差とその原因を検討してみた。その結果、会話文を中心にして幾つかの特徴的事実が分かるようになった。まず先行研究によって指摘された世話浄瑠璃及び上方絵入狂言本の傾向と大体一致する事実をまとめると、次のようである。①単語別に見ると、使役助動詞する、さする、使役動詞さするの順に四段化が進んでいる。②文体的な面から見ると、会話文の四段化は地文の四段化よりはやい。 更に、本稿の考察を通して新しく分かった事実をまとめると、次のようである。①活用形別に見ると世話浄瑠璃及び上方絵入狂言本の傾向、即ち未然形の四段化が連用形の四段化よりはやい傾向とは異なって命令形、終止·連体形、連用形、未然形の順に四段化が進んでいる。②万治期と元禄期間による四段化の遅速が見られる。③同じ時期の上方絵入狂言本の四段化率とはほとんど同じであるが、世話浄瑠璃の四段化よりは高い。つまり、このような考察を通して版本狂言記に見られる使役表現の四段化は単語、活用形、文体、時期によっていろいろな遅速差を見せながら進んだということが分かった。また世話浄瑠璃及び上方絵入狂言本の傾向との共通点と相違点も分かった。

      연관 검색어 추천

      이 검색어로 많이 본 자료

      활용도 높은 자료

      해외이동버튼