청신경초종에 대한 감마나이프 방사선 수술

팽성화,김무성,심홍보,정영균,이선일,정용태,김수천,심재홍,Paeng, Sung Hwa,Kim, Moo Seong,Sim, Hong Bo,Jeong, Yeong Gyun,Lee, Sun Il,Jung, Yong Tae,Kim, Soo Chun,Sim, Jae Hong 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.11

Object : The goals of radiosurgery include preservation of neurological function and prevention of tumor growth. We document the results of gamma-knife radio-surgery for vestibular schwannoma. Method & Object : Eighty-two patients underwent stereotactic radiosurgery for an vestibular schwannoma from October, 1994 to December, 2000. Sixty-five of these patients were followed up for radiological and clinical evaluation. As pregamma-knife modality, surgical resection were done in 23 patients,and V-P shunt in 2 patients. Initial symptoms were headache(n=45), dizziness(n=16), tinnitus(n=17). While normal facial function(House-Brackmann grade 1) was present in 48 patients(73.8%), other patients showed grade 2 function in 8, grade 3 function in 7,and grade 4 function in 2. The Gardner/Robertson scale was used to code hearing function. Male to female ratio was 1:3. Mean tumor volume was $7.98cm^3$. Mean dose delivered to the tumor margin was 14.2Gy,and mean maximal dose was 28.3Gy. Results : Mean follow-up duration of 19.9 months. Thirty-five showed decrease(53.8%) in size, 19 patients(29.2%) stationary, 3(4.6%) initial decrease follow up increase, 5(7.6%) initial increase follow up decrease,and 59 patients (90.8%) were well controlled. Two patients experienced transient facial neuropathy, one transient trigeminal neuropathy, and one transient hearing deterioration. After gamma-knife radiosurgery, ventriculoperitoneal shunt was done in 4 patients. Conclusions : Gamma-knife radiosurgery can be used to treat postoperative residual tumors as well as in patients with concomitant medical problems in patients with preserved hearing function. Gamma-knife radiosurgery is safe and effective method to treat small, medium sized(less than 3cm in extracanalicular diameter), intracanalicular vestibular schwannoma, associated with low rate of cranial neuropathy.

국내 일반은행의 효율성과 생산성지수 변화 분석

김성화(Seong-Hwa Kim) 한국산업경제학회 2016 산업경제연구 Vol.29 No.6

본 연구는 DEA(Data Envelopment Analysis; 자료포락분석)모형과 Malmquist 생산성지수 모형을 이용하여, 글로벌 금융위기 이후 국내 일반은행의 효율성과 생산성지수 변화를 분석하였다. 연구 분석을 위하여 투입변수로는 임직원수, 영업점포, 업무용유형자산을 선정하였으며, 산출변수로는 유가증권, 총대출금, 당기순이익을 선정하였다. 또한 본 연구결과의 신뢰성을 높이기 위한 투입-산출물 자료는 시중은행(6), 지방은행(6)을 대상으로 금융감독원의 금융통계정보시스템에서 제공하는 주요경영지표 등의 최근 8년(2008-2015)간의 패널자료를 활용하였다. 주요 분석결과, 시중은행인 우리은행, KEB하나은행, 한국씨티은행과 지방은행인 경남은행이 모든 분석기간에 걸쳐 CCR효율성, BCC효율성, 규모효율성이 다른 DMU에 비해 효율적인 운영과 규모의 경제가 발생하는 것으로 나타났다. 그러나 시중은행인 한국스탠다드차타드은행과 경남은행을 제외한 대부분의 지방은행은 효율성이 상대적으로 낮게 나타났는데, 그 이유는 글로벌 금융위기 직후 떨어졌던 부실채권의 비율이 최근 다시 상승추세를 보이면서 은행의 여신건전성이 나빠지고, 경영의 효율성 지표를 나타내는 자기자본이익률(ROE)도 크게 떨어졌기 때문인 것으로 분석된다. 총요소생산성은 분석기간 동안 대부분 1보다 높은 생산성 변화를 보였으며, 기하평균 총생산성도 1.6% 정도 증가된 것으로 나타났다. 이는 국내 일반은행의 기술효율성이 향상되었으며, 기술변화 측면에서도 기술이 진보된 것으로 나타났기 때문이다. 따라서 총요소생산성의 향상은 효율적 생산단위의 변화를 의미하는 기술효율성이 향상되거나 혹은 기술자체의 변화를 의미하는 기술변화가 진보되거나 혹은 둘 다에 의해서 기인된다고 할 수 있다. 이에 따라 은행들은 리스크 및 영업비용 관리를 통하여 안정적인 부실채권비율을 유지하고, 위험자산을 축소시키며, 지속적인 비용효율성 개선을 통하여 수익성과 효율성 모두를 제고시켜야 할 것이다. This paper analyzed the efficiency and productivity index change of domestic commercial banks from 2008 to 2015 since global financial crisis by using the DEA(Date Envelopment Analysis) and Malmquist model. The inputs were the number of employees, sales stores and fixed assets, whereas the outputs were considered amount of securities, total loans and current period net profit. The empirical main results are as follows. First, Woori Bank, KEB-Hana Bank, Korea CitiBank and Kyongnam Bank showed a high degree of efficiency in CCR, BCC and scale efficiency. This mean that those are operated by economics of scale and effective management compared to the other DMUs. However, Korea Standard Chartered Bank and most of the regional banks appeared relatively low levels of efficiency in contrast with Kyongnam Bank, because ratio of non-performing loans shows latest upward trend, also the banks have greatly deteriorated the credit integrity and return on equity. Second, The Malmquist analysis shows that the average total factor productivity index was increased by about 1.6% from 2008 to 2015 because technical efficiency and technical exchange were progressed of the domestic commercial banks. Therefore, Improving of total factor productivity can be attributed to progress of technical efficiency or to develop of technical exchange, or is able to both.

"가르기-모으기" 놀이가 수학 학습장애 아동의 가감산 능력에 미치는 효과

김성화 ( Seong Hwa Kim ),강병주 ( Byeong Joo Kang ),최정미 ( Jeong Mee Choi ),변찬석 ( Chan Suk Byun ) 한국정서.행동장애아교육학회(구.한국정서학습장애아교육학회) 2006 정서ㆍ행동장애연구 Vol.22 No.3

택시 운전자의 응급처치 시행의지에 대한 응급처치 교육 효과

성화용 ( Hwa Yong Seong ),박득현 ( Deuk Hyun Park ),윤유상 ( Yoo Sang Yoon ),박경혜 ( Kyung Hye Park ),김양원 ( Yang Weon Kim ) 대한외상학회 2013 大韓外傷學會誌 Vol.26 No.3

Purpose: After a traffic accident, first-aid performed within the first few minutes is important for the injured in terms of survival, future health, and quality of life. Taxi drivers have more possibility of witnessing traffic accidents because they spend much time on the road. If taxi drivers are well trained and can perform first-aid in a correct manner, they will play an important role in pre-hospital emergency medical services. We investigated the effect of first-aid training on taxi drivers` willingness to perform emergency care. Methods: We provided first-aid training for 600 deluxe taxi drivers in Busan in 2012. The subjects were given a questionnaire to answer at the beginning and at the end of first-aid training. Results: 427 out of 600 deluxe taxi drivers answer our questionnaire completely. 93 out of 427 deluxe taxi drivers answered that they had first-aid training within past 3 years(21.8%). 323 taxi drivers have witnessed a traffic accident(76%). 45 out of 323 deluxe taxi drivers who witnessed a traffic accident answered that they provided first-aid to victims(14.0%). After first-aid training, taxi drivers` willingness to perform emergency care was increased compared to that before training. The failed group of taxi drivers that had same or decreased willingness after first-aid training had a low level of education than the successful group that had increased willingness after first-aid training. Conclusion: First-aid training increased taxi drivers` willingness to perform emergency care. So Taxi drivers should be encouraged more to undertake and maintain first-aid training. For more volunteering of first-aid training and improvement in the effect of first-aid training, a graded education program for taxi drivers with a low level of education should be developed, and a policy on giving credit for completing first-aid training course and for carrying out first-aid needs to be formulated.

칼시토닌 분비 췌장 내분비 종양을 동반한 다발내분비샘종양 1형 1예

김홍익 ( Hong Ik Kim ),최준혁 ( Jun Hyeok Choi ),오훈규 ( Hoon Kyu Oh ),배성화 ( Sung Hwa Bae ),류헌모 ( Hun Mo Ryoo ),김성규 ( Seong Gyu Kim ),강선미 ( Sun Mi Kang ) 대한내과학회 2012 대한내과학회지 Vol.83 No.6

Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant hereditary disorder characterized by the combined occurrence of tumors of the parathyroid gland, exocrine pancreas, and anterior pituitary gland. Calcitonin-secreting pancreatic endocrine tumors are rare, and calcitonin-secreting pancreatic endocrine tumors with MEN1 have not been reported in Korea. A 46-year-old woman was admitted for a right breast cancer operation. Abnormal blood chemistry findings were hypercalcemia and elevated calcitonin. The patient was diagnosed with a calcitonin-secreting pancreatic endocrine tumor, left thyroid papillary carcinoma, right breast invasive ductal carcinoma, a thymic carcinoid tumor, left adrenal adenoma, uterine myoma, and adenomyosis by computed tomography scan, and with pituitary macroadenoma by brain magnetic resonance imaging. We present this case with a review of the literature, because it is the first reported calcitonin-secreting pancreatic endocrine tumor with MEN 1 in Korea. (Korean J Med 2012;83:817-822)

DEA모형을 활용한 인증종합물류기업의 효율성 분석에 관한 연구

김성화(Seong Hwa Kim) 한국무역연구원 2013 무역연구 Vol.9 No.1

Improving the efficiency of logistics companies and logistics industry has become the top priority to all decision-making units for the era of unlimited competition. The purpose of this paper is to analyze the efficiency of 33 certified integrated-logistics Korean companies(CILKC) for 11 years from 2001 to 2011 by using the DEA(Date Envelcpment Analysis) and Malmquist models. The empirical main results are as follows. First, Dongjin, UCTC, Pantos, and KMTC in CCR efficiency and Dongjin, UCTC, Glovis, Pantos, and KMTC in BCC efficiency show the efficient score 1. Dongjin, KMTC, UCTC, Pantos, DTC, KUKBO, CKLlNE, and KCTC whose average values of scale efficiency are 1. This means that those are operated by the economies of scale and effective management, compared to the other CILKC. Second, The Malmquist analysis shows that the average total factor productivity index(0.9994) was decreased by about 6% from 2001 to 2011, because of the backward step of technical change in the logistic industry due the global economic recession. The policy implications are as follows. ① scale expansion by revitalization of 3PL, ② strengthening the custorrer-oriented service, ③ comprehensive plan by govemment for logistics rationalization, ④ tax reduction with consulting support plan for changing cargo companies into 3PL, ⑤ continuous policy for enhancing the efficiency.

이온빔 합성법에 의해 증착된 다이아몬드성 카본 필름의 구조 및 특성

김성화(Seong-Hwa Kim),이광렬(Kwang-Ryeol Lee),은광용(Kwang Yong Eun) 한국진공학회(ASCT) 1999 Applied Science and Convergence Technology Vol.8 No.3(2)

End hall type 이온건을 이용하여 다이아몬드성 카본필름을 합성하였다. 탄소의 공급원으로는 벤젠을 사용하였으며, 합성에 참여하는 이온의 에너지를 조절하기 위해 DC, pulsed DC 그리고 250 ㎑의 고주파 전원을 사용하여 -100에서 -800 V까지의 바이어스를 기판에 인가하였다. 본 연구에서는 바이어스 전원의 종류에 따른 합성거동과 바이어스 전압에 따른 필름의 구조와 기계적 특성의 변화를 관찰하였다. 바이어스 전압이 인가되지 않은 상태에서 합성된 필름은 39±4 ㎬의 경도와 290±50 ㎬의 탄성계수를 가지고 있었다. 이는 PACVD에 의해 합성된 필름보다 2배 내지 6배에 이르는 우수한 기계적 물성이다. 필름의 합성속도는 Kaufman type 이온건을 사용하는 것보다 매우 높았으며, 이는 end hall type 이온건이 가지고 있는 높은 이온빔 전류에 기인하는 결과이다. 필름의 물성이나 구조는 바이어스의 종류에 관계없이 바이어스 전압에만 의존하였다. 바이어스 전압이 증가함에 따라 필름의 구조는 흑연화 되고 3차원적 상호결합의 양이 감소하였으며, 이에 따라 잔류응력, 경도 그리고 탄성계수가 모두 감소하였다. Diamond-like carbon (DLC) films were deposited by using end hall type ion gun. Benzene gas was used for the generation of carbon ions. In order to systematically control the ion energy, we applied to the substrate DC, pulsed DC or 250 ㎑ medium frequency bias ranging from -100 to -800 V. We investigated the deposition behaviors depending on the type of the bias voltage, and the structure and properties of the films for various bias voltages. Without applying the bias voltage, DLC films of superior mechanical properties of hardness 39±4 ㎬ and elastic modulus 290±50 ㎬ (2 to 6 times better than those of the films deposited by plasma assisted CVD method) could be obtained. Deposition rate was much higher than when using Kaufman type ion source, which results from higher ion beam current of end hall type ion gun. The mechanical properties and atomic bond structure were independent of the bias voltage type but intimately related with the magnitude of the bias voltage. With increasing the negative bias voltage, the structure of the films changed to graphitic one resulting in decreased content of three dimensional inter-links. Degradation of the mechanical properties with increasing bias voltage could be thus understood in terms of the content of three dimensional inter-links.

염수환경에 의한 UPN139 탄소/에폭시 복합재 물성치 변화 연구

김중진(Joong-Jin Kim),문철진(Cheol-Jin Moon),허성화(Seong-Hwa Hur),이청락(Cheng-Rak Lee),권진회(Jin-Hwe Kweon),최진호(Jin-Ho Choi) 대한기계학회 2008 대한기계학회 춘추학술대회 Vol.2008 No.10

Experiments were performed to investigate the effect of salt water on the mechanical properties of UPN-139 carbon-epoxy composite after 0, 1, 3, 6, 9 and 12 months immersion in 3.5% salt water. Waterproof painting and sealing tape were applied to protect the water absorption on the both cutting sides and taps of specimens. Test results show that while the tensile properties in fiber and matrix direction did not decrease considerably until 12 months of immersion, shear strength and modulus decreased gradually from nine months of the immersion. The reduction of shear strength and modulus were 9.5% and 10.8% of the values of dry specimens without exposure to salt water, respectively .

치성 각화낭종의 임상적 연구

성화식(Hwa-Sik Seong),이주민(Ju-Min Lee),황대석(Dae-Seok Hwang),김용덕(Yong-Deok Kim),김욱규(Uk-kyu Kim),김종렬(Jong-Ryoul Kim),정인교(In-Kyo Chung),신상훈(Sang-Hun Shin) 대한구강악안면외과학회 2009 대한구강악안면외과학회지 Vol.35 No.2

Purpose: The purpose of this study is to investigate the clinical and histological features of odontogenic keratocyst Patients and Methods: A retrosective review of 100 patients who were diagnosed as odontogenic keratocyst by hitological findings during the period of January 2000 and December 2005 in the Dept. of Oral and Maxillofacial surgery Pusan National University was consecuted. For each patient, age, sex, location of lesion, initial diagnosis by radiographic features, treatment procedure, hitologic findings and recurrance rate were evaluated. Results: In this study, OKC has male prevalance to female by 1.38:1, and most likely occurs during third decade. The most common site of lesion was mandibular ramus region(34.6%) and the most common symptom was swelling(50%). The most common initial diagnosis by radiographic findings was OKC and cyst enucleation was the most common treatment method. The recurrance rate was 28% and existence of daugther cyst is thought to be most convincing factor for prediction of recurrence. Conclusion: In this study, total recurrence rate was 28% and existence of daugther cyst is thought to be most convincing factor for prediction of recurrence. But, since 97% of patients were treated by enucleation and adjuntive excision, further styudy is need about concordance of recurrence rate with surgical method.

Improvement of Transglycosylation Efficiency using a Glycosynthase Mutant derived from Thermoplasma acidophilum ${\alpha}$-Glucosidase

황성민,서성화,박인명,최경화,김도만,차재호,Hwang, Sung-Min,Seo, Seong-Hwa,Park, In-Myoung,Choi, Kyoung-Hwa,Kim, Do-Man,Cha, Jae-Ho The Korean Society for Microbiology and Biotechnol 2012 한국미생물·생명공학회지 Vol.40 No.2

Glycosynthase는 친핵성 아미노산을 비친핵성 아미노산으로 치환하여 당전이 산물의 가수분해를 막아서 당전이 효율을 증가시킬 수 있다. 이전 연구에서 본 실험실은 열에 안정하고 산에 강한 Thermoplasma acidophilum 유래의 ${alpha}$-glucosidase (AglA)가 당전이 활성이 있음을 입증하였으나 시간이 지남에 따라 당전이 산물이 가수분해 되었다. 이러한 AglA의 당전이 효율을 개선하기 위하여 친핵성 아미노산인 아스파라긴산을 글리신으로 치환하였다. 이 치환된 glycosynthase는 니켈 친화력 크로마토그래피를 통하여 정제되었으며, 정제된 돌연변이 단백질의 배당체를 합성하는 능력이 말토오스를 공여체로 그리고 p-nitrophenyl-${alpha}$-D-glucopyranoside($pNP{\alpha}G$)를 수용체로, 그리고 $pNP{\alpha}G$가 당공여체 및 수용체로 이용될 수 있는지 검사하였다. Glycosynthase를 이용한 당전이 산물의 수율은 약 42.5%를 보였으며 시간이 지남에 따라서 가수분해되지 않았다. 박막 크로마토그래피법을 이용한 반응산물의 분석은 수용체의 높은 농도에서 기존의 효소보다 많은 양의 배당체를 합성할 수 있음을 보여주었고, 특히 중성보다 낮은 pH 영역에서 가장 높은 활성을 보여줌을 확인하였다. 이러한 결과는 glycosynthase가 산업적으로 배당체를 합성하는데 유용성이 크다는 것을 나타낸다. Glycosynthase is an active site nucleophile mutant enzyme, prepared from glycosidase, which is capable of synthesizing oligosaccharide derivatives without the hydrolysis of the product. Thermoacidophilic ${\alpha}$-glucosidase of Thermoplasma acidophilum (AglA) exhibits a transglycosylating activity yielding various glycosides. AglA was converted to glycosynthase by the substitution of the catalytic nucleophile Asp-408 residue into non-nucleophile glycine in order to increase its ability to synthesize various glycosides by transglycosylation. The glycosynthase mutant was purified by Ni-NTA chromatography and its glycoside-synthesizing activity was measured by using an external nucleophile, sodium formate buffer, providing maltose as a donor and p-nitrophenyl-${\alpha}$-D-glucopyranoside ($pNP{\alpha}G$) as an acceptor, respectively. In addition, $pNP{\alpha}G$ was examined for its feasibility to act as both a donor and an acceptor, and products were compared with those of the wildtype enzyme. The mutant enzyme was found to catalyze the formation of a specific product from $pNP{\alpha}G$ with a yield of 42.5% without further hydrolysis, while the wild-type enzyme produced two $pNP{\alpha}G$ products at low yields. The results demonstrate the possibility of satisfactory yields for the reactions in the presence of small amounts of acceptor, and demonstrate that the high activity of the mutant, at pHs below neutrality, was applicable in the transfer of glucose from the natural donor.