Stabs에서 DIL로의 번역기의 구현

김성엽(Seong-Yup Kim),장종현(Jong-Hyun Jang),김성재(Seong-Jae Kim),김승호(Sung-Ho Kim) 한국정보과학회 2001 한국정보과학회 학술발표논문집 Vol.28 No.1A

교환기 소프트웨어와 같은 통신 시스템은 분산 병렬적인 수행 특성을 가지며, CHILL의 디버깅 환경인 TECH는 이러한 특성을 반영하고 있다. 최근의 교환기 소프트웨어 개발에 C 언어가 많이 사용되고 있는데, C 디버킹 환경은 이러한 특성을 잘 반영하지 못한다. 따라서, C 언어로 작성된 프로그램을 TECH에서 디버깅할 수 있다면 새로운 환경을 구축하지 않고도 기존의 환경을 이용함으로써 비용과 시간을 줄일 수 있다. 그러나, 두 환경의 디버깅 정보인 Stabs 정보와 실행 파일을 분석하는 분석기, 분석된 정보를 각각에 해당하는 DIL에 대응시키는 대응기, 대응된 DIL 정보를 생성하는 생성기로 구성된 Stabs에서 DIL로의 번역기를 구현하였다.

하지 외상 후 진단된 Arteriovenous Malformation의 치료

김성엽 ( Seong Yup Kim ),진성찬 ( Sung Chan Jin ) 대한외상학회 2013 大韓外傷學會誌 Vol.26 No.4

Congenital arteriovenous malformation is rare disease. Endovascular treatment is one of the important modality in the treatment of arteriovenous malformation. We report a successful treatment case of arteriovenous malformation with endovascular treatment.

복부구획증후군 환자에서 발생한 심부정맥혈전증

김성엽 ( Seong Yup Kim ),진성찬 ( Sung Chan Jin ) 대한외상학회 2013 大韓外傷學會誌 Vol.26 No.4

Abdominal compartment syndrome is one cause of deep vein thrombosis of lower extremity. Although prophylactic dose of anticoagulation agent is safely started after 24~48 hours without the evidence of active bleeding, there may be bleeding complication related to invasive procedure which trauma victims undergo. Inferior vena cava filter should be considered in the treatment plan of this complex situation.

신이식 후 초기의 적절한 Tacrolimus 치료 농도

민상일(Sang-Il Min),김성엽(Seong Yup Kim),안상현(Sang Hyun Ahn),정진구(Chin Koo Chung),민승기(Seung-Kee Min),하종원(Jongwon Ha),김상준(Sang Joon Kim) 대한외과학회 2010 Annals of Surgical Treatment and Research(ASRT) Vol.79 No.6

Purpose: Immunosuppressive regimen based on reduced-dose Tacrolimus (TAC) is widely accepted in the field of renal transplantation. However, optimal targetsfor TAC whole blood trough concentrations during the early period after kidney transplantation remain uncertain. Methods: A total of 184 consecutive adult renal transplant recipients with triple immunosuppression (TAC/Mycophenolate/corticosteroid) were included in this study. According to the trough level of TAC at day 7 after transplantation, patients were classified as low TAC concentration (LT, <10 ng/㎖, n=85), intermediate TAC concentration (IT, 10∼15 ng/㎖, n=75), and high TAC concentration (HT, >15 ng/㎖, n=24) groups. Rate of acute rejection, graft function and side effects of TAC within 1 yr after transplantation were evaluated. Results: There was no difference in trough concentrations of TAC at 2 weeks, 1 month, 3 months, 6 months and 12 months after transplantation among the three groups. Significantly higher incidence of acute rejection within 2 weeks after transplantation was observed in LT group compared with IT and HT groups (17.4%, 5.6% and 4.8%, respectively, P=0.037). HT patients showed significantly better estimated glomerular filtration rates until 6 months after transplantation than IT and LT patients (75.5±24.8 vs. 63.8±12.8 and 64.3±15.2 ㎖/min at 6 months, P=0.03). There was no significant difference in TAC toxicity in terms of post-transplant diabetes and renal toxicity. Conclusion: Short-term high TAC exposure immediately after kidney transplantation may provide lower incidence of acute rejection and better restoration of graft function compared with low or intermediate TAC exposure.

고의로 섭취한 커터칼날의 내시경 및 보존적 치료 증례 보고

박종민 ( Jong Min Park ),김성엽 ( Seong Yup Kim ),정일용 ( Il Yong Chung ),김우식 ( Woo Shik Kim ),신용철 ( Yong Chul Shin ),김영철 ( Yeong Cheol Kim ),박세혁 ( Sei Hyeog Park ) 대한외상학회 2013 大韓外傷學會誌 Vol.26 No.4

Food bolus impaction is the most common cause of esophageal foreign body obstruction in adults. Other causes include intentional ingestion in psychiatric patients or prison inmates. We experienced successful treatment of a patient with intentional ingestion of multiple sharp foreign bodies(25 cutter and razor fragments). A 47-year-old male patient who was suffering from chronic alcoholism was admitted, via the emergency room, with dysphagia and neck pain. He was suffering from alcoholic liver cirrhosis and psychiatric problems, such as chronic alcoholism, anxiety disorder and insomnia. The patient had intended to leave the hospital after having swallowed the sharp objects. Plain radiographs and computed tomography (CT) scan showed multiple, scattered metal fragments in the esophagus, stomach, and small bowel. We performed emergent endoscopy and successfully removed one impacted blade in the upper esophagus using by a snare with an over tube. The rest of the fragments had already passed through the pylorus, so we could not find them with endoscopy. We checked the patient with simple abdominal radiographs and careful physical examinations every day. All remaining fragments were uneventfully excreted through stool during the patient`s 6 day hospital stay. Finally, we were able to confirm the presence of the objects in the stool, and radiographs were negative. The patient was discharged without complications after 14 days hospital stay and then was followed by the Department of Psychiatry.

복강내 종양으로 오인된 외상성 혈종: 증례보고

박종민 ( Jong Min Park ),김성엽 ( Seong Yup Kim ),정일용 ( Il Yong Chung ),김우식 ( Woo Shik Kim ),신용철 ( Yong Chul Shin ),김영철 ( Yeong Cheol Kim ),박세혁 ( Sei Hyeog Park ) 대한외상학회 2013 大韓外傷學會誌 Vol.26 No.4

Blunt abdominal trauma is commonly encountered in the emergency department. The lack of historical data and the presence of distracting injuries or altered mental status, from head injury or intoxication, can make these injuries difficult to diagnose and manage. We experienced a case of traumatic organized hematoma misdiagnosed as intra-peritoneal tumor with intestinal obstruction. A 52-year-old homeless male patient who have chronic alcoholism was admitted via emergency room with infra-umbilical abdominal pain. At admission, he was drunken status and so we could not be aware of blows to the abdomen. He had a unknown large operation scar on mid abdomen. A computed tomography (CT) scan showed the intestinal obstruction of the ileum level with 5.5cm sized mesenteric tumor. We performed adhesiolysis and widely segmental resection of small bowel including tumor with side-to-side anastomosis due to great discrepancy in size. He stated later that he was a victim of the violence before 3 weeks. A final pathologic report revealed well encapsulated, traumatic mesenteric hematoma with organizing thrombi, ischemia and abscess formation with multiple adhesion bands. Finally, the patient was discharged without complications on postoperative day 14.

혈역학적으로 안정된 복부 전벽 자상 환자의 개복 수술 결정에서 Single-contrast CT의 역할

조장환 ( Jang Hwan Jo ),김중석 ( Joong Suck Kim ),김영철 ( Yeong Cheol Kim ),정일용 ( Il Yong Chung ),박종민 ( Jong Min Park ),안은정 ( Eun Jung Ahn ),김은영 ( Eun Young Kim ),박세혁 ( Sei Hyeog Park ),김성엽 ( Seong Yup Kim ) 대한외상학회 2014 大韓外傷學會誌 Vol.27 No.4

Purpose: To assess the accuracy and role of single-contrast computed tomography (CT) in the management of anterior abdominal stab wound (AASW). Methods: During 8-years period, single-contrast CT was performed in 21 hemodynamically stable AASW patients (age range, 22-64 years; median age, 45 years), including 19 men and 2 women. CT scans were evaluated by one trauma surgeon and one senior resident to determine the depth of injury(peritoneal violation or not), and abnormal findings of intraperitoneal cavity associated with stab injury. We retrospectively reviewed medical records regarding operative findings. Results: Nine patients underwent abdominal surgery and 12 patients nonoperative management. In the abdominal surgery group, abnormal CT findings included peritoneal violation in 14 patients and abnormal intraperitoneal cavity findings in 5 patients. There was no statistical significant difference regarding abnormal CT findings between abdominal surgery group and nonoperative management group. Among the nine abdominal surgery patients, therapeutic laparotomy was performed on 4 patients. The positive predictive value (PPV) and negative predictive value (NPV) of peritoneal violation to predictive therapeutic laparotomy were 28.6% and 100%, respectively. In addition, the PPV and NPV of abnormal intraperitoneal cavity CT findings to predict therapeutic laparotomy were 40.0% and 87.5%, respectively. There was no statistical significant difference regarding the abnormal CT findings between therapeutic laparotomy group and non therapeutic laparotomy group. Conclusion: CT is a good adjunctive method to evaluate hemodynamicaly stable AASW patients. If peritoneal violation is not seen on CT scan, conservative treatment on local wound may be safely performed without additional abdominal surgery. However, further study is warranted to evaluate the exact role of CT in the diagnostic workup of AASW patients. [ J Trauma Inj 2014; 27: 145-50 ]

외상 및 외상진료체계의 인식도 조사

정일용 ( Il Yong Chung ),김중석 ( Joong Suck Kim ),김영철 ( Yeong Cheol Kim ),김성엽 ( Seong Yup Kim ) 대한외상학회 2014 大韓外傷學會誌 Vol.27 No.4

Purpose: Trauma is one of the most common and lethal causes of death in Korea, especially in people under the age of 40. However, a considerable percentage of trauma patients are lost each year due to the scarce resources of the trauma system. The purpose of this study was to determine the recognition of trauma and trauma system. Methods: From April 8th to 22nd, 2014, visitors and in-patients in our medical center were interviewed and surveyed with a questionnaire, which included 28 questions regarding the trauma system, such as the most common cause of death, the locations of trauma centers, the importance of trauma centers, and consent for supporting trauma centers financially. Results: The majority of the respondents recognized trauma as a common cause of death; this was particularly true for people younger than 40. Most respondents’ expectancy for the optimal time for trauma patient transport was high, recognizing that major trauma patients should receive urgent care. The respondents felt that trauma centers are important and needed, just as much as police stations and libraries are. Among 178 respondents, 140 (80.5%) were willing to financially support the trauma system. Conclusion: The respondents were aware of the seriousness of trauma and generally agreed on the need for trauma centers. In order to meet the needs and the demands of the people, and to reduce preventable death rate, the trauma system should be improved not only in quality but also in quantity with better and more facilities and manpower, with the aid of publicity from trauma organizations and funding from the government. [ J Trauma Inj 2014; 27: 165-9 ]

쥐의 허혈성 하지 모델에서 VEGF를 함유한 Nanoparticle의 투여 효과

안상현(Sang Hyun Ahn),민상일(Sang-Il Min),김성엽(Seong Yup Kim),민승기(Seung-Kee Min),양한광(Han-Kwang Yang),김상준(Sang Joon Kim),하종원(Jongwon Ha) 대한외과학회 2010 Annals of Surgical Treatment and Research(ASRT) Vol.79 No.4

Purpose: Vascular endothelial growth factor (VEGF) is one of the factors regulating angiogenesis. For angiogenesis, the local concentration of VEGF has to be maintained. Because of its short half-life, VEGF has been conjugated with nanoparticles. Some nanoparticles, such as poly (lactic-co-glycolic acid (PLGA)) or polyethylenimine (PEI) are commonly used in this field, but have weak points such as faster release than expected and cell toxicity. We investigated the effect of core/shell nanoparticles including lecithin lipid cores in the ischemic hindlimb model. Methods: Mice were anesthetized and a region of the common femoral artery and vein was ligated and excised. Hindlimb ischemic mice (n=28) were divided randomly into four groups: Control group (normal saline, n=7), mouse VEGF group (mVEGF, n=7), nanoparticle including mVEGF group (N-mVEGF, n=7), and nanoparticle/hydrogel mouse VEGF group (NH-mVEGF, n=7). The drug was injected postoperatively into the thigh muscle of the ischemic limb. Perfusion, capillary number and H&E stain were assessed 28 d after treatment. Results: The capillary number increased in N-mVEGF and mVEGF group (P=0.026). Improvements of ischemic limb perfusion were inferior in N-mVEGF, NH-mVEGF groups (P=0.006) compared to other groups. Mice received N-mVEGF, NH-mVEGF treatment showed significant inflammation in the H&E staining. Conclusion: Sustained VEGF delivery via core/shell nanoparticle with lecithin core did not show improved perfusion rate despite an increase in capillary number. Furthermore, vacuolization and induction of inflammation requiring a different composition of nanoparticle should be tested.

연료전지 전극의 기공구조와 산흡수도

김성엽,설용건,이태희,노용우 연세대학교 산업기술연구소 1991 논문집 Vol.23 No.2

Pore structure and acid absorbancy of carbon electrode of phosphoric acid fuel cell were studied by varying carbon black, PTFE loading, and fabricating method for Denka black. Results showed that the primary pore(micro pore) of the carbon electrode included the micro space formed around the carbon particles regardless of the carbon black(Vulcan XC-72 and Denka black) used, and that addition of PTFE and pressing of electrode influenced mainly the secondary proe. The acid absorbancy of electrode was decreased as PTFE loading was increased and Denka black showed more hydrophobic than Vulcan XC-72 with three times in saturation time and one-half in acid absorbancy.