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정용태,김수천,김무성,김석강,심재홍,이선일 인제대학교 1998 仁濟醫學 Vol.19 No.2
1994년 10월부터 1998년 6월까지 인제대학교 부산백병원 신경외과에 입원하여 뇌간종양으로 감마나이프방사선 수술을 시행하였던 10예를 대상으로 임상 분석을 시행하였다. The brainstem tumor may cause serious, sometimes lethal, neurological deficits. Therapy and control of brainstem tumor should avoid injury to the brainstem. Gamma Knife radiosurgery can deliver a high radiation dose precisely to a target with minimum damage outside the target area, an improvement in local growth control of tumors located in brain stem may be expected without adverse effects. Ten brainstem tumor patients underwent Gamma Knife radiosurgery. 7 cases were pontomedullary tumors and others were midbrain tumor. 8 cases were focal tumors, 2 cases were diffuse tumor. The mean marginal doses were 10.8Gy. After mean follow-up of 18.5 months, 4 cases were decreased in size, 4 cases were stationary, 2cases were increased. Gamma Knife radiosurgery was effective in local growth control of brainstem tumors without producing side effects. Longer follow-up intervals will be needed to assess the long-term effectiveness of the technique. Sometimes, an alternative treatment design, such as fractionated stereotactic radiosurgery, will be required.