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RISS 인기검색어
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- 저자 : 김벼리 ( Byuh Ree Kim ) (검색결과 1 건)
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소아 급성호흡곤란증후군에서 Pediatric Acute Lung Injury Consensus Conference 정의의 임상적 적용
김벼리 ( Byuh Ree Kim ),김수연 ( Soo Yeon Kim ),설인숙 ( In Suk Sol ),김윤희 ( Yoon Hee Kim ),김경원 ( Kyung Won Kim ),손명현 ( Myung Hyun Sohn ),김규언 ( Kyu-earn Kim ) 대한천식알레르기학회(구 대한알레르기학회) 2019 Allergy Asthma & Respiratory Disease Vol.7 No.1
Purpose: Despite improved quality of intensive care, acute respiratory distress syndrome (ARDS) significantly contributes to mortal ity in critically ill children. As pre-existing definitions of ARDS were adult-oriented standards, the Pediatric Acute Lung Injury Consen sus Conference (PALICC) group released a new definition of pediatric ARDS. In this study, we aimed to assess the performance of PALICC definition for ARDS risk stratification. Methods: Total 332 patients who admitted to the intensive care unit at Severance Hospital from January 2009 to December 2016 and diagnosed as having ARDS by either the PALICC definition or the Berlin definition were retrospectively analyzed. Patient charac teristics and mortality rates were compared between the individual severity groups according to both definitions. Results: The overall mortality rate was 36.1%. The mortality rate increased across the severity classes according to both definitions (26% in mild, 37% in moderate and 68% in severe by the PALICC definition [P<0.001]; 20% in mild, 32% in moderate and 64% in se vere by the Berlin definition [P<0.001]). The mortality risk increased only for severe ARDS in both definitions (hazard ratio [95% con fidence interval]: 2.279 [1.414-3.672], P=0.001 by the PALICC definition; 2.674 [1.518-4.712], P=0.001 by the Berlin definition). There was no significant difference in mortality discrimination between the 2 definitions (difference in integrated area under the curve: 0.017 [-0.018 to 0.049]). Conclusion: The PALICC definition demonstrated similar discrimination power on PARDS’ severity and mortality as the Berlin defini tion. (Allergy Asthma Respir Dis 2019;7:44-50)
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