청장년기 아토피피부염 환자의 살의 질에 관한 연구

김민희,김자혜,신상호,노영호,유현정,김훈,김규곤,윤화정,고우신,Kim, Min-Hee,Kim, Ja-Hye,Shin, Sang-Ho,Roh, Youn-Ho,Yu, Hyun-Jung,Kim, Hoon,Kim, Kyu-Kon,Yoon, Hwa-Jung,Ko, Woo-Shin 대한한방안이비인후피부과학회 2006 한방안이비인후피부과학회지 Vol.19 No.2

Background : Many doctors are under a bias toward clinical severity in patients with atopic dermatitis. But the various studios show that atopic dermatitis may produce a range of impacts on the qualify of lift . Nevertheless there is much to be desired about the association between the quality of lift and atopic dermatitis in the department of Dermatology in Korean medicine. Objective : This study was conducted to investigate the impact of the atopic dermatitis on quality of life and explore prognostic factors that influence outcomes. Methods : 70 patients were recruited in this study rho write out more than 90% of Skindex-29 questionnaires. The function of total scores and three domain scores and SCORAD index was investigated and the correlation of each domain scores also . Result : The total scores, showed significant correlation with three domain scores in atopic dermatitis. The correlation of each three domain scores were significant. SCORAD index showed significant correlation with three domain scores and total scores. Conclusion : In this study atopic dermatitis efface of the quality of life in physical, social, and psychological factors. So we considered to the quality of life as well as clinical severity in patient with atopic dermatitis.

각질하 농포성 피부병 한방 치험 1례

김민희,윤영희,유승민,최인화,Kim, Min-Hee,Yun, Young-Hee,Yu, Seung-Min,Choi, In-Hwa 대한한방안이비인후피부과학회 2011 한방안이비인후피부과학회지 Vol.24 No.2

Objective : Subcorneal pustular dermatosis is a rare, chronic neutrophilic dermatoses that was first described in 1956. The eruption is characterized by flaccid pustules grouped in a circinate pattern on normal or erythematous skin. We treated a case of subcorneal pustular dermatosis in one patient; there have been no former reports of this disease treated by oriental medicine. We present this case because we considered it to be useful as a possible Oriental medicine treatment for subcorneal pustular dermatosis, and something that canbe used for further study of neutrophilic dermatoses. Method : We used herbal medication, acupuncture, herbal wet dressing, herbal ointment, cupping therapy and phototherapy during treatment. We assessed symptoms during treatment and also carried out blood tests through out. Result : We observed and treated a case of subcorneal pustular dermatosis patient and after treatment the patient's objective and subjective symptoms showed noticeable improvement. Conclusion : We suggest that subcorneal pustualr dermatosis can be treated by Oriental medicine therapy effectively. We expect these study results will help provide useful evidence of Oriental medicine as an effective treatment for subcorneal pustualr dermatosis.

한방화장품이 안면부의 탄력 개선에 미치는 영향

김민희,윤영희,조가영,최인화,Kim, Min-Hee,Yun, Young-Hee,Cho, Ga-Young,Choi, In-Hwa 대한한방안이비인후피부과학회 2012 한방안이비인후피부과학회지 Vol.25 No.3

Objective : The purpose of this study was to evaluate the effect of korean herbal cosmetics for facial skin elasticity. Methods : We recruited patients and divided them to cosmetics group and control group randomly. We provided korean herbal cosmetics to cosmetics group and subjects in cosmetics group applied the provided cosmetics for 4 weeks. Control group waited and applied cosmetics that had previously used for 4 weeks. We assessed all subjects in 0 week, 2 weeks and 4 weeks. Primary assessment instrument was moire topography photo scale. Second assessment instrument was skin moisture, oiliness and elasticity which assessed with skintouch system v1.0, detox/regeneration questionnaire score and self-evaluating facial wrinkle/looseness score. Result : Moire topography photo scale improved in cosmetics group than control group significantly. Skin moisture and elasticity assessed with skintouch system improved in cosmetics group than control group significantly while skin oiliness assessed with skintouch system have not improved significantly. Detox/regeneration questionnaire score and self-evaluating facial wrinkle/looseness score improved in cosmetics group than control group significantly. Conclusion : Korean herbal cosmetics application might be effective method for facial skin elasticity.

유전적(遺傳的) 분석법(分析法)에 의한 사상체질(四象體質)의 연구(硏究)

김민희,김경석,지상은,최선미,조동욱,Kim, Min-hee,Kim, Kyung-seok,Chi, Sang-en,Choi, Sun-mi,Cho, Dong-wuk 사상체질의학회 1999 사상체질의학회지 Vol.11 No.1

This study was carried out for the objectification and clinical application of the Sasang Constitutional Medicine(四象醫學). So, the Taeum Soyang, Soum groups were classified by diagnostic rules of Sasang constitution, and investigated by Amp-FLP method far genetic difference. The Amp-FLP was one of the most frequently used human genetic analysis methods which adopts STR typing. In this study, 100 genomic DNA samples of Taeum, Soyang, Soum constitution group were analysed by Amp-FLP method. Allele frequencies of four tetrameric short tandem repeat(STR) loci(TPOX, LPL, D21744, and D13S317) were determined in Taeum, Soyang, Soum groups. The heterozygosities and the polymorphism information content(PIC) values of forur STR loci were 0.812 and 0.789 in D3S1744, 0.811 in D13S317, 0.466 and 0.417 in LPL, and 0.625 and 0.561 in TPOX, respectively. The allele distribution of four STR loci was statistically evaluated. It was found out that the allele distribution of four STR loci was not significantly different among different constitutions. But all loci were found to be highly polymorphic in Taeum, Soyang, Soum groups. It was found out in this study that Taeum, Soum groups are genetically more related each other than they are related to Soyang groups.

보통 건선의 한방치료 경과에 대한 후향적 고찰

김민희,이병철,윤영희,최인화,Kim, Min-Hee,Lee, Byung-Chul,Yun, Young-Hee,Choi, In-Hwa 대한한방안이비인후피부과학회 2013 한방안이비인후피부과학회지 Vol.26 No.1

Objective : To observe effects of TKM (Traditional Korean Medicine) treatment for psoriasis vulgaris. Methods : We did retrospective chart review for 32 psoriasis vulgaris patients who had been treated by TKM. TKM treatment included acupuncture, herb med, external herbal solution and moxibustion. Result : PASI (Psoriasis Area and Severity Index) 75 responding rate at treatment week 16 was 71.9%. Mild symptom patients' improvement rate and moderate to severe symptom patients' improvement rate was similar. Mean PASI score was increased until treatment week 4 to 8, and after that period, mean PASI score was decreased. Conclusion : This study suggest that TKM may be an effective treatment for psoriasis vulgaris.

왕궁리 유적지에서 발굴된 고대 토양의 부분 특성 연구

김민희,서민석,Kim, Min-Hee,Seo, Min-Seok 국립문화재연구소 2004 保存科學硏究 Vol.25 No.-

The archeological remains usually exist in some excavated ancient soils. The ancients oils are buried in underground with the environmental, biological and social facts for circumstantial evidence at past times. Consequently, it is very important thing to carry out scientific analysis of the ancient soils side by side with archeological study. In this study, we accumulated some basic data for scientific analysis of 5 kinds of ancient soils excavated at Wanggung-ri, Iksan city. So we obtained some characterizations of organic chemical source, ancient parasite egg, and some seeds in the soils. The organic sources showed the content of high organic material as 7~22%, and strong acidic condition as pH 2~6. It is indicated that Wanggung-ri soils have included so many organic materials from the degradation of biological remains. Most of all, we searched a lot of eggs of parasite Trichuris trichiura and so it is possible that this area had been a ancient toilet at that times. The more scientific analysis of the soils will be showed us about the utility of the area, ancient dietary life style, ancient environment and ancient human diseases.

2차원 레이저 스캔을 이용한 로봇의 산악 주행 장애물 판단

김민희,곽경운,김수현,Kim, Min-Hee,Kwak, Kyung-Woon,Kim, Soo-Hyun 한국군사과학기술학회 2012 한국군사과학기술학회지 Vol.15 No.1

Obstacle detection is much studied by using sensors such as laser, vision, radar and ultrasonic in path planning for UGV(Unmanned Ground Vehicle), but not much reported about its characterization. In this paper not only an obstacle classification method using 2-dimensional LMS(Laser Measurement System) but also a decision making method whether to avoid or traverse the obstacle is proposed. The basic idea of decision making is to classify the characteristics by 2D laser scanned data and intensity data. Roughness features are obtained by range data using a simple linear regression model. The standard deviations of roughness and intensity data are used as measures for decision making by comparing with those of reference data. The obstacle classification and decision making for the UGV can facilitate a short path to the target position and the survivability of the robot.

전자선 조사를 통해 제조한 카복시메틸셀룰로스 수화젤의 팽윤거동

김민희,조동환,권오형,박원호,Kim, Min Hee,Cho, Donghwan,Kwon, Oh Hyeong,Park, Won Ho 한국섬유공학회 2016 한국섬유공학회지 Vol.53 No.6

In this study, carboxymethylcellulose (CMC) hydrogels were successfully prepared by electron beam irradiation. The morphology and mechanical properties of the hydrogels were examined by scanning electron microscopy and tensile testing, which indicated that the compressive strength of the hydrogels was closely associated with their pore wall thickness. In addition, the equilibrium swelling ratio of the hydrogels was evaluated in both distilled water and different physiological media, which indicated that their maximum swelling ratio was higher in water than that in physiological media. Moreover, their maximum swelling ratio decreased with an increase in salt concentration. The fabricated cellulose-based hydrogels were shown to be promising for applications in drug delivery systems and the field of biomaterials.

으름열매 추출물의 항산화 활성 및 피부미용 효과

김민희,최태부,Kim, Min-Hee,Choe, Tae-Boo 한국응용과학기술학회 2015 한국응용과학기술학회지 Vol.32 No.3

으름열매는 폴리페놀과 사포닌과 같은 페놀성 물질을 많이 함유하고 있다. 본 연구는 세포실험을 통해 으름열매 추출물의 항산화활성을 확인하고, 피부에 적용하였을 때 수분과 유분, 멜라닌과 홍반변화의 효과를 측정하였다. 항산화 효과 측정결과, 농도 의존적으로 폴리페놀, 플라보노이드, DPPH소거능이 상승한 것으로 확인되었고, 으름열매 추출물 크림을 사용하였을 때 수분함량 변화, 유분함량 변화, 멜라닌지수, 홍반지수의 감소가 통계적으로 유의미한 변화를 보여 으름열매 추출물 함유 화장품이 피부개선을 위한 기능성화장품으로서 활용 가능성을 확인할 수 있었다. 따라서 본 연구에서는 으름열매 추출물은 독성을 나타내지 않으면서도 피부보습, 피부개선효과를 가진 천연 및 기능성화장품 소재로서 활용 가능성이 있다고 사료된다. Akebia quinata fruit(AQF), as identified in the preceding paper, polyphenols and other phenolic components of saponin also has similar or higher levels. The purpose of this study is to analyze the effect of akebia quinata fruit extract, well-known for soothing, anti-oxidizing effects, on the improvement of the moisture, sebum, melanin, erythema content of facial skin. As a result of measuring DPPH radical scavenging activity to examine independent anti-oxidation of AQF, there was a slight scavenging activity. Compared to before the usage of cream, a group who used cream with akebia quinata fruit extract showed a very slight increase in the moisture content and slight decrease in the sebum, melanin, erythema on their faces after 4 weeks of tests, indicating that there was some statistically significant changes found. This study proves that the akebia quinata fruit(AQF) extract has a positive effect on the overall improvement of facial skin and it also implies that the akebia quinata fruit extract has high potential as an ingredient of cosmetic products.

토양분석을 통한 고고학적 해석-익산 왕궁리 수혈유구 토양을 대상으로

김민희,서민석,정용재,전용호,Kim, Min-Hee,Seo, Min-Seok,Chung, Yong-Jea,Jeon, Yong-Ho 국립문화재연구소 2005 保存科學硏究 Vol.26 No.-

Coprostanol is a metabolic product of cholesterol, formed by microbial action in the mammalian gut. This chemical compound is the major sterol in human and has been routinely studied as a biomarker of sewage pollution in marine and lacustrinesediments. This has led to the search for coprostanol as a biomarker in archaeologicalsoils, in order to detect the presence of fecal material. In this study, five samples of archaeological soils excavated at Wanggung ri, Iksancity, were used to assess the possibility of using coprostanol as indicators of ancient human activity in archaeological areas. The sampled soils were analyzed MXRD,EDXRF for their physical and chemical properties. And coprostanol was analysed byGC/MSD, using SIM method to detect and quantify specific compound. The results showed the soils were composed of quartz and feldspars, inorganicelement such as $SiO_2$, $Al_2O_3$, $Fe_2O_3$ etc. Moreover, the result from the analysis wasindicated that the specific compound is coprostanol. The coprostanol was determined at $0.16~1.01\mug$/g in the range of concentrations. This finding indicate that clear promise exists for the exploitation of coprostanol as biomarker of ancient human activity inarchaeological survey. Therefore such studies can serve to increase the confidence we place on biomarker-based methodologies for assessing fecal pollution. The application of this methodology has proved a simple and effective way of searching for that pattern in successively more aged deposits either known or suspected to contain fecal material. And the more scientific analysis of the soils will be showed to utility of the area ancient dietary life style, ancient environment.