노인에서 턱관절 장애와 골밀도의 관련성에 관한 예비 연구

김문종 대한노년치의학회 2022 대한노년치의학회지 Vol.18 No.2

Purpose: The aim of this study is to investigate and compare bone mineral density in patients with temporomandibular disorders (TMD) and healthy controls to confirm the relationship between TMD and osteoporosis. Methods: 107 TMD patients and 50 healthy controls were included in this study. Among the TMD patients, 50 were diagnosed with osteoarthritis in at least one joint. Mandibular cortical width (MCW) and panoramic mandibular index (PMI) were calculated in all participants using panoramic radiographs to evaluate bone mineral density. Results: The mean age was not significantly different between the TMD patients and controls. There were significantly more female subjects in the TMD group than in the controls. The TMD patients with osteoarthritis displayed lower values of MCW and PMI than those without osteoarthritis. However, only the difference in the value of MCW showed statistical significance. Conclusion: The patients with TMD have lower bone mineral density than the healthy controls. Additionally, compared to the TMD patients without osteoarthritis, the TMD patients with osteoarthritis have reduced bone mineral density. These findings suggested that osteoporosis may be related to the pathophysiology of TMD and osteoarthritis.

후기 발현 남성 성선기능저하증에 대한 2006 대한남성갱년기학회 호르몬치료 권고안

김문종,이유미,서주태,양대열,문두건,박남철,김제종 대한남성과학회 2008 The World Journal of Men's Health Vol.26 No.1

Androgen deficiency in the aging male has become a topic of increasing interest and debate throughout the world. The evidence from results showing that testosterone decrease progressively with age and that a significant percentage of men over the age 60 years have serum testosterone levels that are below the lower limits of young adults(age 20∼30) men suggest that older hypogonadal men will benefit from testosterone replacement therapy. Long term data on the effects of testosterone replacement therapy in the older population, however, are limited and specific risk data on the prostate and cardiovascular systems are needed. Key questions of functional benefits that may retard frailty of the elderly are not yet available. The recommendations described below were based on document suggested by the International Society of Andrology(ISA), the International Society for the Study of the Aging Male(ISSAM) and the European Association of Urology(EAU) in 2005. The academic committee of the Korean Society for the Aging Male Research(KOSAR) suggested these recommendations to provide the appropriate information about investigation, treatment and monitoring for late-onset hypogonadism in aging Korean men following an annual meeting in October 2006.

고령 남성에서의 테스토스테론의 역할

김문종 대한임상노인의학회 2007 대한임상노인의학회지 Vol.8 No.1

Frailty 예방과 치료를 위한 전략

김문종,김창오,이영진 대한임상노인의학회 2008 대한임상노인의학회지 Vol.9 No.1

한 지역사회 병원에서의 가정의의 산부인과 진료내용에 대한 분석

김문종,유태욱,신승용,이상화,곽기우,윤방부 대한가정의학회 1991 Korean Journal of Family Medicine Vol.12 No.9

태아체중 예측에 있어서 초음파단층상 측정한 태아대퇴장경치의 유용성

김문종,황성한,서경,박용원,박찬규 대한산부인과학회 1986 Obstetrics & Gynecology Science Vol.29 No.12

Treatment Outcomes of Venlafaxine and Duloxetine in Refractory Burning Mouth Syndrome Patients

김문종,고홍섭 대한안면통증∙구강내과학회 2019 Journal of Oral Medicine and Pain Vol.44 No.3

Purpose: Venlafaxine and duloxetine have been shown to be effective in the treatment ofneuropathic pain disorders. However, knowledge about the efficacy of venlafaxine and duloxetineon burning mouth syndrome (BMS) is still insufficient. The purpose of this studywas to investigate the efficacy of venlafaxine and duloxetine on refractory BMS patients. Methods: Twelve refractory BMS patients who were prescribed venlafaxine or duloxetinewere included in this study. These patients did not respond to previous administration ofclonazepam, alpha-lipoic acid, gabapentin, and nortriptyline. All participants were the primarytype of BMS patients who had no local and systemic factors related to the oral burningsensation. The intensities of oral symptoms following venlafaxine or duloxetine administrationwere compared with those before administration and at baseline. Results: Venlafaxine and duloxetine were prescribed to four and nine patients, respectively. One patient was prescribed both medications in turn. Among them, only two patientsshowed improvement of oral symptoms without side effects. In the other ten patients,symptoms failed to improve. Six of them reported that the drug was ineffective, and fourof them stopped taking the medications on their own due to intolerable side effects, such asinsomnia, constipation, drowsiness, dizziness, and xerostomia. Conclusions: Venlafaxine and duloxetine may only relieve oral symptoms in a minority ofrefractory BMS patients. Further large-scale studies are needed to determine the potentialclinical factors that could predict the efficacy of venlafaxine and duloxetine.

The Circadian Rhythm Variation of Pain in the Orofacial Region

김문종,정진우,고홍섭,박지운 대한안면통증∙구강내과학회 2015 Journal of Oral Medicine and Pain Vol.40 No.3

All living organisms have a biological clock that orchestrates every biological process andfunction, and this internal clock operates following a circadian rhythm. This biological clockis known to influence various clinical indicators such as blood pressure and body temperature. Also, the fluctuation of signs and symptoms of diseases including pain disorders are affectedby circadian rhythm. It has been reported that the pain intensity of various somatic and neuropathicpain disorders show unique pain patterns that depend on the passage of time. The generationof pain patterns could be explained by extrinsic (e.g., physical activity, tactile stimulation,ambient temperature) and also intrinsic factors (neural and neuroendocrine modulation)that are related to the circadian rhythm. It is important to recognize and identify the individualpain pattern in pain therapy to approve treatment outcome. Moreover, chronotherapeuticswhich considers pain patterns and pharmacokinetics in context of the circadian rhythm couldproduce greater analgesia in response to medication. However, only a limited number of studieshandle the issue of pain patterns according to circadian rhythm and chronotherapeutics inthe orofacial region. The present review intends to reflect on the most recent and relevant dataconcerning the bidirectional relation between pain disorders of the orofacial region and circadianpatterns.

초기 임신에서 진단된 EDWARD 증후군 1 예

김문종,이정형,이채원,전배성,소영환,박성근 대한산부인과학회 1999 Obstetrics & Gynecology Science Vol.42 No.4

Edward 증후군 즉, Trisomy 18은 두번째로 흔한 상염색체 삼체성 이상으로 다발성 선천성 기형과 연관이 있다. Trisomy 18의 전형적인 특징은 자궁내 발육 지연과 선천성 기형을 동반한 양수과다증 등이다. 이 증후군에서는 성장 결함 뿐만 아니라 일반적으로 예후도 극히 나쁘기 때문에 산전 진단이 매우 중요하다. 산전 초음파 검사에서 이 증후군으로 의심되는 이상 소견이 나타나면 세포유전학적 검사를 시행해야 하며 태아가 Trisomy 18로 확인되면 임신중절을 고려해야 한다. 이에 보고자들은 임신 14주에 본원 산전 초음파 검사로 다발성 기형을 동반한 Edward 증후군을 경험하였기에 간단한 문헌 고찰과 함께 보고하는 바이다. Edward syndrome, or Trisomy 18, is the second most common autosomal aberration associated with multiple congenital abnormalities. The hallmark of trisomy 18 is polyhydramnios with intrauterine growth retardation and congenital abnormalities. Growth deficiency is well-known part of this syndrome and, therefore, it is particularly important to make the antenatal diagnosis of trisomy 18 because of universally poor prognosis. Identification of a fetus with trisomy 18 is an important variable in planning obstetric management ; therefore increasing awareness of the sonogaphic appearance should improve the detection rate of this syndrome, since the sonographic abnormalities described in this report can be indications for cytogenetic evaluation. We experienced a case of Edward syndrome with multiple anomalies antenatally diagnosed and so present it with brief review of literatures.

남성 갱년기

김문종 대한임상노인의학회 2001 대한임상노인의학회지 Vol.2 No.1