림프절 전이가 동반된 진행성 위암 환자에서 수술 전 항암요법으로 시행한 FOLFOX 치료로 완전 관해를 보인 1례

김명희,정현용,문희석,성재규,강선형,김주석,Myung Hee Kim,Hyun Yong Jeong,Hee Seok Moon,Jae Kyu Sung,Sun Hyun Kang,Ju Seok Kim 대한소화기암연구학회 2018 Journal of digestive cancer reports Vol.6 No.1

국소적인 진행성 위암의 근치적인 치료는 수술이 첫 번째 방법이다. 하지만 위암을 진단받은 환자 중에서 약 30% 만이 수술이 가능한 진행성 위암으로 진단을 받으며 그 중 약 40-60% 만이 R0 절제술이 가능하다. 저자들은 위 주위 림프절과 복강 림프절, 장막을 침범한 진행성 위암을 진단받은 환자를 3주간의 수술 전 항암화학요법으로 치료하였고, 근치적인 목적으로 위 절제술을 시행하였다. 조직병리검사에서 완전히 괴사된 종양 조직을 관찰할 수 있었고, 수술 후 현재까지 3차례의 추가적인 전신 항암화학요법을 시행하고 있으며, 추적 복부 전산화단층촬영에서 재발을 시사하는 소견을 보이지 않았다.

허균과 매창의 시조

김명희(Kim Myung-Hee) 한국시조학회 2005 시조학논총 Vol.22 No.-

허균과 매창은 사대부와 기녀의 관계로 알게 된 사이다. 그러나, 허균은 매창을 여성 문학인으로 재능을 인정하고 평생 詩友로 존경하며 사랑한 사이였다. 허균은 천재 시인, 혁명가, 이상향을 꿈꾸는 평등주의자여서 여성과 서얼을 인간으로 대접하려는 따뜻한 성품의 소유자였다. 그러한 허균이 매창을 중국에 기녀시인 설도에 비견하고 매창을 조선의 최고 기녀시인으로 손꼽는 데는 매창 시의 한 특성이 있다고 본다. 그녀의 시조는 상실감에 가득한 비애 가운데서도 임과의 재회를 꿈꾸는 소망의식이 가득한 시 의식을 지니고 있다고 본다. 또한, 그녀는 사대부와의 관계에서 나름대로 등거리 사랑을 추구하였고 그에 성공하였기 때문에 성적 욕망의 대상인 기녀 신분이면서도 성이 뒤로 앉은 貞操 어린 여성으로 자리 잡아 사대부들의 존경과 시선을 한 몸에 받은 시인이었다. 허균의 폄하 발언으로 얼룩진 평가를 재평가하고, 매창의 시가 비애 의식에 머물러 있지 않고 소망의식으로 발돋움하였다는 것을 밝히고 있다. Woman is individual than social. passive than active and defensive than offensive. In addition. they taught that these characters are femine in the middle ages and the feudal ages. The closed and limited society was common to women in the feudal society. But there were many classes in women society from the humble maids to the queen in Chosun Dynasty. And Kisaeng(a singing and dancing girl) was free in comparison with the noble women. But Kisaeng were also limited as woman. They could write literary works according to the playing with poems and something like that with the men of intellectual class. But this also gave them sorrows. In the feudal Chodun Dynasty. men recognized the noble women specially and this is the special quality of Chosun. The Confucianism which was the existense thought of Chosun, discriminated between men and women. But women studied secretly and wrote poems pouring their thoughts and emotions. Maechang wrote many Shijo (Korean verse) with the delicacy description and the real expression. The reason Chosun woman Maechang could wrote Shijo which is free from the feudal limitations is that she was Kisaeng, She had a love as a Kisaeng who had to play with the intellectual men. But she loved Yu hee-kyoung. So she preserved chastity for him and waited only him. This is the love of both body and soul. And love with Hu kyoon friendship which is far from love. The limited love because of the spatial parting and the discrepancy of the social position is the most sorrowful. 10 years love with the intellectual men such as Hu kyoon is a friendship with poems. It was not love, so they had to temperate, So they love each other as a literary friend. We can see the feminist Hu kyoon, and see Hu kyoon who loved the literature and assert the renovation. Maechang was free from the chastity but she preserved it because of her proud. She dreamed the fairyland as Hunansulhun. Because she couldn't realize love. She ended her literature and Kisaeng life at 38 years old. There are literature of nansulhun as a noble woman and of maschang as a Kisaeng in Chosun Dynasty.

의식 없는 말기환자 가족의 연명치료 중단 결정 경험

김명희,강은희,김미영,Kim, Myung-Hee,Kang, Eun-Hee,Kim, Mi-Young 한국호스피스완화의료학회 2012 한국호스피스.완화의료학회지 Vol.15 No.3

Purpose: The purpose of this study is to understand family members' experience of deciding to withdraw life-sustaining treatments for terminally-ill patients in an unconscious state. Methods: Data were collected by performing an in-depth interview with eight terminally-ill patients' family members who decided to withdraw life-sustaining treatments. Colaizzi's phenomenological method was used for data analysis. Results: Questions were classified into 12 groups and finally into five categories. The five categories were about family members' frustration with patient's condition, emotional preparation for the patient's death upon medical professionals' recommendation, patient's wishes, exhaustion due to caring and past experiences related to life-sustaining treatment. Conclusion: Using the five categories, hospice and palliative professionals could better understand family members' decision making experience of withdrawing life-sustaining treatments for terminally-ill patients. Based on that, the family members could be provided with appropriate counseling and care, which in turn could improve hospice and palliative care intervention. 목적: 본 연구의 목적은 의식 없는 말기환자 가족의 연명치료 중단 결정 경험을 이해하기 위함이다. 방법: 자료는 의 없는 말기환자의 연명치료 중단 결정을 한 8명의 가족으로부터 심층면담을 통해 수집하였다. Colaizzi의 현상학적 분석 방법이 자료 분석을 위해 사용되었다. 결과: 주제는 12개의 주제모음으로 분류되었고, 12개의 주제모음은 마침내 5개의 범주로 통합되었다. 5개의 범주는 환자상태로 인한 절망감, 의료진의 권고에 마음을 비움, 환자의 바램, 돌봄으로 인한 가족의 소진, 연명치료와 관련된 과거의 경험이었다. 결론: 다섯 개의 범주를 통하여 의식 없는 말기환자 가족의 연명치료 중단 결정 과정에서 발생할 수 있는 현상들을 이해함으로써 적절한 상담과 간호를 제공하여 보다 바람직한 호스피스 완화의료 중재가 필요하다고 본다.

금산 폐탄광지역의 오염이 하천수에 미치는 영향

김명희,민일식,송석환 ( Myung Hee Kim,Ell Sik Min,Suck Hwan Song ) 한국산림과학회 1997 한국산림과학회지 Vol.86 No.4

The research was carried out to investigate the contamination of stream water by the acid mine drainage originated from the abandoned coal mines and coal waste rock in Keumsan, Chungnam. The pH, sulfate and chemical compositions in the stream water were analyzed. At the polluted sites, the pH of stream water was the strong acid, ranging from 3.46 to 4.29. The pH shows negative correlations with sulfate, manganese, copper, zinc, iron and magnesium concentrations. Sulfate concentrations of the polluted stream water, 236.73 - 310.53㎎/ℓ, had 10 times more than those of the non-polluted stream water. The concentrations of heavy metals, Mn and Fe, in the polluted water were 0.56 - 0.83㎎/ℓ and 5.89 - 10.58㎎/ℓ, respectively. The Mn concentrations were 20 times higher than those of the non-polluted stream water. Compared with those in the non-polluted stream water, the Mg and Ca concentrations in the polluted stream water were high because of leaching from rock and soil to water by the acidifications. Calculated AMDI(Acid Mine Drainage Index) values are low in the polluted stream water, relative to those of the non-polluted water.

실행기능장애 아동에 대한 감각통합치료 캠프의 효과 - 사례보고

김명희,김미선,Kim, Myung-Hee,Kim, Mi-Sun 대한감각통합치료학회 2004 대한감각통합치료학회지 Vol.2 No.1

Objective : To identify the effect of intensive sensory integration therapy through 5 days camp programs for children with dyspraxia Methods : A comparison of quantitative date and qualitative description between before and after sensory integration therapy camp described adaptative response of children and individual home-based program was designed and therapist educated parents about it. Results : The problem of control and apraxia which children have was improved rather than before camp and adaptive response increased. Conclusion : Follow-up study is needed to observe and investigate the effect of continuous treatment after camp participation.

${\gamma}-Cyclodextrin$ Glycosyltransferase 생산균주의 분리, 동정 및 효소 생산조건

김명희,임영희,배경숙,오태광,손천배,Kim, Myung-Hee,Lim, Young-Hee,Bae, Kyung-Sook,Oh, Tae-Kwang,Sohn, Cheon-Bae 한국응용생명화학회 1997 Applied Biological Chemistry (Appl Biol Chem) Vol.44 No.4

A cyclodextrin glycosyltransferase-producing bacterium was newly isolated from soil using alkaline pH medium containing 1% $Na_2CO_3$. The isolated strain was identified as Bacillus brevis by morphological and biochemical characteristics, and fatty acid composition and designated Bacillus brevis CD162. The strain showed the best enzyme production of 0.9 unit/ml after 96 hrs of culture at $30^{\circ}C$ in a medium of 2.0% soluble starch, 0.75% yeast extract, 0.5% bacto peptone, 0.2% $K_2HPO_4$ 0.05% $MgSO_4{\cdot}7H_2O$, and 1.5% $Na_2CO_3$ at initial pH 10.2. Cyclodextrin glycosyltransferase 생산균주를 토양으로부터 분리하여 형태학적, 생화학적 그리고 균주의 세포벽 지방산 조성분석에 의해 Bacillus brevis로 동정하였고, Bacillus brevis CD162로 명명하였다. 또한 배지조성에 따른 cyclodextrin glycosyltransferase의 최적생산조건을 검토한 결과, 2.0% soluble starch, 0.75% yeast extract, 0.5% bacto peptone, 0.2% $K_2HPO_4$, 0.05% $MgSO_4{\cdot}7H_2O$, 1.5% $Na_2CO_3$ (pH 10.2)의 배지 조건에서 $30^{\circ}C$에서 96시간 배양하였을 때 가장 높은 효소생산인 0.9 unit/ml을 얻을 수 있었다.

실시간 태스크의 마감시간 만족을 위한 캐쉬 최적 분할 형태의 분석

김명희,주수종,Kim, Myung-Hee,Joo, Su-Chong 한국정보처리학회 1997 정보처리논문지 Vol.4 No.11

This paper presents an analysis on the optimal partitioning configuration of cache (memory) for meeting deadlines of periodic and aperiodic real-time task set. Our goal is not only to decrease the deadline missing ratio of each task by minimizing the task utilization, but also to allocate another tasks to idle spaces of cache. For this reason, we suggest an algorithm so that tasks could be allocated to cache segments. Here, the set of cache segments allocated tasks is called a cache partitioning configuration. Based on how tasks allocate to cache segments, we can get various cache partitioning configurations. From these configurations, we obtain the boundary of task utilization that tasks are possible to schedule, and analyze the cache optimal partitioning configuration that can be executed to minimize the task utilization. 본 논문은 실시간 시스템에서 주기 및 비주기적 태스크들의 마감시간 만족을 위한 캐쉬(캐쉬 메모리)의 최적 분할 형태를 분석한다. 연구 목적은 태스크들의 가용비용을 최소화하여 태스크들의 마감시간 위반율을 줄일 뿐 아니라 캐쉬의 유휴공간을 다른 태스크에게 할당시키기 위함이다. 이를 위해 캐쉬의 분할공간에 태스크들을 할당시키기 위한 캐쉬 분할공간 할당 알고리즘을 제시한다. 여기에서 태스크들이 할당된 캐쉬 분할공간들의 집합을 캐쉬 분할 형태라고 한다. 태스크들이 분할공간에 어떻게 할당되는가에 따라 다양한 캐쉬 분할 형태들을 얻을 수 있다. 이러한 캐쉬 분할 형태들로부터 스케쥴링 가능한 태스크들의 가용비용의 한계범위와 태스크들이 최소 가용비용으로 실행 할 수 있는 캐쉬의 최 적 분할 형태를 분석한다.

요양병원 입원 노인의 우울 관련요인

김명희,김윤경,Kim, Myung-Hee,Kim, Yun-Kyung 대한예방한의학회 2012 대한예방한의학회지 Vol.16 No.3

Objective : The study was designed to identify the factors related to depression of the elderly patients in geriatric hospital. Method : The subjects consisted of 198 old people who admitted in three geriatric hospital located in Daegu City. The Data was collected through interview with questionnaire from July 16 to August 16, 2012. Results : The general characteristics which significantly affected depression was perceived health status(F=18.158, p=.000). There was a slightly negative correlation between activity daily living & depression(r=-.378,p=.000) and strongly negative correlation between life satisfaction & depression(r=-.573, p=.000). Among the factors related to depression of the subjects, life satisfaction had highest expanatory power of 32.8%. Conclusion : The finding of this study provide useful information for constructing an intervention program and care for the elderly patients in geriatric hospital with depression.

Partial Purification and Properties of Invertase from Jerusalem Artichoke Tuber

김명희,전덕영,Kim, Myung-Hee,Jhon, Deok-Young 생화학분자생물학회 1988 한국생화학회지 Vol.21 No.4

돼지감자에서 sucrose의 가수분해를 촉매하는 invertase(EC 3.2.1.26)를 71배로 부분 정제하였다. 전기 영동을 한 결과 순수효소는 한개의 polypeptide chain으로 구성되어 있었고, 그 분자량은 86,000이었다. 효소활성에 필요한 적정 pH와 적정온도는 각각 pH 7.0, $40^{\circ}C$였다. 이 효소는 sucrose에 대하여 높은 가수분해 활성도를 보였으나, inulin에 대해서는 전혀 작용하지 않았다. Sucrose에 대한 이 효소의 Km값은 24.7 mM이었다. The invertase (EC 3.2.1.26), which catalyzes the hydrolysis of sucrose, has been purified 71-fold from Jerusalem artichoke tuber. Electrophoresis showed that the native enzyme is consisted of single polypeptide chain of 86,000 daltons. Optimum pH and temperature for the enzyme action were pH 7.0 and $40^{\circ}C$, respectively. The enzyme exhibited high hydrolytic activity to sucrose, but no activity on inulin. The enzyme had an apparent Km of 24.7 mM for sucrose.

뇌혈관 환자에 대한 간호진단 적용 분석

김명희 대구보건대학 1996 대구보건대학 論文集 Vol.16 No.-

간호진단의 실무적용을 증진시키고 간호의 질을 높이기 위해 대구시내에 소재한 Y의료원 신경계 변동에 입원한 환자 102명에게 적용된 간호진단수 총 109개를 NANDA회의에서 채택된 간호진단명 105개에 준하여 분석한 결과 환자 1인당 평균1개를 사용하였으며 총 사용 NANDA 간호진단명은 9개로 대상자 102명중 가장 많이 사용된 간호 진단은 안위의 변화 44.0%, 불안 19.3%, 부적절한 개인적 대응 12.8%로서 높게 나타났다. 본 연구의 결과 적용된 간호진단의 종류 및 빈도가 매우 낮았으며 간호진단에 대한 사정도구개발의 연구와 간호사들에게 지속적인 보수교육이 강화되어야 한다고 생각한다. This research was done for the improvement of practical appliance of Ng. diagnosis and for the elevation of nursing guality(level). I analized the Ng. diagnosis with 109 diagnosis used by NANDA conference from 102 patients who were admitted for Neuro Surgery Ward of Y medical Center which is in Taegu. Ther general characteristics of the patients are as follows ; by sex, men were 57 cases(55.9%) and women were 45 cases(45.1%). In age, 26~29 were I case(1.0%), 30~39 were 10 cases(9.8%), 40~49 were 30 cases(29.4%), 50~59 were 32 cases(31.4%), 60~69 were 26 cases(25.5%), and over 70 were 3 cases (2.9%). In diagnosis of the patients, Cerebral Infarction were 52 cases(50.9%), Intracerebral Hemorrhage were 20 cases(19.6%), Subarachnoid Hemorrhage were 12 cases(11.8%), Epidural Hemorrhage were 7 cases(6.9%), Subdural Hemorrhage were 5 cases(4.9%), Aneurysm were 4 cases(3.9%), Cerebrovascular Accident were 2 cases(2.0%). I used all 109 Ng. diagnoses which means one person used about 1.0 of NANDA'S diagnoses. All used NANDA'S was 9 diagnoses. The most popular diagnoses were alteration in Comfort(44.0%), Anxiety(19,3%), Ineffective individual Coping(12.8%) in 102 cases. Bae showed ineffective air way clearance(48.4%), impaired Physical mobility, ineffective Breathing pattern, Knowledge deficit, All of them were 41.9% in her diagnosis analysis research of Open Heart Surgery Patients. Kang showed self care deficit(27.7%), skin integrity(23.4%), tissue perfusion, alteration in cerebral area(16.4%), and high risk for infection(0.6%), in her diagnosis analysis research of brain disease patients. Park(1987) showed the representative diagnosis of high risk for injury, altered nutrition less than body reguirements, knowledge dificit, sleep pattern disturbance, and fluid volume excess, in her evaluations, of the original and revealational research rate of five diagnosis in patients with CAAH or CAVH. When we consider the specifics of each patient we can determine how the Ng assessment reveals that patients problems differ according to their disease. Signs and symptoms are one thing, and nursing requests are another. As the specific response-formal analysis of 9 Ng. Diagnoses in which the most popular diagnoses were Emotion(33.4%), Exchanging(22.2%), Moving(12.0%), choosing(11.1%) Knowing(11.1%) but Communicating and Relating, Valuing, Perceiving were not applied.