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김만중,강현수,Kim, Man-Joung,Kang, Hyun-Soo 한국정보통신학회 2014 한국정보통신학회논문지 Vol.18 No.3
본 논문은 사용자의 입력, 색상 및 깊이 정보를 이용한 의미론적 물체 분할 방법을 제안한다. 의미있는 영역을 깊이영상에서 유사한 깊이 정보와 사용자 스트로크 입력의 중심에 위치한다고 가정한다. 제안된 방법은 스트로크 입력을 이용하여 관심 영역을 설정하고, 색상과 깊이 정보를 이용하여 의미있는 영역을 검출한다. 구체적으로 제안방법은 관심영역에 대해 색상과 깊이 정보를 이용한 과분할 과정과 과분할 영역에 대해 깊이 정보를 이용한 의미론적 물체 추출과정으로 구성되어 있다. 과분할 과정에서 적응적 임계값 적용 및 형태학적 기울기에 대한 적응적인 가중치 적용을 통한 마커 추출 방법을 제안하였다. 의미론적 물체 추출과정에서는 관심영역의 가장자리 영역에서 내부 영역으로의 순서대로 전체 깊이의 평균과 차이를 이용하여 추출하고자 하는 물체 영역인지 아닌지를 결정하도록 하였다. 실험 결과에서 제안한 방법이 효과적으로 의미있는 물체 추출 결과를 얻을 수 있음을 보인다. This paper presents a semantic object extraction method using user's stroke input, color, and depth information. It is supposed that a semantically meaningful object is surrounded with a few strokes from a user, and has similar depths all over the object. In the proposed method, deciding the region of interest (ROI) is based on the stroke input, and the semantically meaningful object is extracted by using color and depth information. Specifically, the proposed method consists of two steps. The first step is over-segmentation inside the ROI using color and depth information. The second step is semantically meaningful object extraction where over-segmented regions are classified into the object region and the background region according to the depth of each region. In the over-segmentation step, we propose a new marker extraction method where there are two propositions, i.e. an adaptive thresholding scheme to maximize the number of the segmented regions and an adaptive weighting scheme for color and depth components in computation of the morphological gradients that is required in the marker extraction. In the semantically meaningful object extraction, we classify over-segmented regions into the object region and the background region in order of the boundary regions to the inner regions, the average depth of each region being compared to the average depth of all regions classified into the object region. In experimental results, we demonstrate that the proposed method yields reasonable object extraction results.
신증후출혈열환자의 한탄 및 서울바이러스에 대한 중화항체 형성
김만중 고려대학교 의과대학 1986 고려대 의대 잡지 Vol.23 No.3
The production of neutralizing antibodies against Hantaan and Seoul viruses in sera of five patients diagnosed as typical Korean hemorrhagic fever were investigated using plaque reduction neutralization test. Cross reactivity of sera of the patients to Hantaan and Seoul viruses which are related but distinct antigenically were also studied. The patients with Korean hemorrhagic fever have been bled by weekly intervals from 3 days to 66 days after the onset of illness and sera were prepared and stored in -65℃ until use. Neutralizing antibody titers against Hantaan and Seoul viruses mere determined by a serum dilution-plaque reduction neutralization (PRN) method employing immunoperoxidase staining. In gerneral, the antibodies were detected from as early as 3 days after the onset of disease. The peak titers were reached at around 2 weeks after the onset of illness and the antibodies were persisted up to 66 days although the titers were decreased slowly. All sera used were neutralized Hantaan viruses in higher titers in contrast with lower titers with Seoul viruses. It can be concluded that HFRS patients in this study were infected with Hantaan virus in rural areas of Korea.
김만중,조승렬,노순백,채종구,정춘해,홍순표,조건국 朝鮮大學校 附設 醫學硏究所 1986 The Medical Journal of Chosun University Vol.11 No.1
Clinical observation on 127 cases of aplastic anemia at diagnosed at Chosun University Hospital from January, 1976 to December, 1985 were reviewed. 1. The annual distribution of aplastic anemia showed no significant annual change during this Priod. The highest incidence were observed on second decade, 75 cases (59.1%) were observed below 30 years old and male to female sex ratio was 1.4 : 1. 2. Exposure to possible toxic agent were in 3o cases(27.6%), among which chloramphenicol was counted in 8 cases (6.3%), herb agent 6 cases (4.7%), analgesics 5 cases (3.9%), heavy metal 4 cases (3.1%), benzene 3 cases (2.4%), insecticides 3 cases (2.4%), parathion 3 cases (2.4%), and other various agents. The unknown causes are largely distributed 92 cases (72.4%). 3. Initial symptoms and signs on admission were anemia and pallor in 79 cases(62.2%), dizxness and weakness in 61 cases (48.0%), bleeding in 57 cases (44.9%), fever in 30 cases (23.6%), Petechia and ecchymosis in 22 cases (17.3%), hepatomegaly in 21 cases (16.5%), splenomegaly in 12 cases (9.5%), headache in 7 cases (0.5%) and other symptoms and signs in 13 casea (10.2%). 4. Among the laboratory findings, severe anemia with hemoglobin level of 5.0gm/㎗, or less were noted in 58 cases (45.7%). Neutrophil count of less than 2,000/㎣ found in 51 cases (10.2%) and platelet count of less than 50,000/㎣ in 68 cases (53.5%). Findings of bone marrow aspiration and biopsy were revealed hypercellularity in 4 cases (3.2%), normocellularity in 13 cases (10.2%), hypocellularty in 93 cases (73.2%) and dry tap in 17 cases (13.4%). 5. On the 95 cases which were follow-up for evaluation of prognosis, remission in 19 cases (15.0%), steady states in 58 cases (45.7%) and death in 18 cases (14.2%) were noted, So, Prognosis was not favorable in 32 cases (25.2,%). The causes of death of 18 cases by follow-up evaluation revealed infection in 7 cases (38.9%). bleeding in 5 cases (27.8%) and progressive anemia in 4 cases (22.2%), The unknown causes were counted in 2 cases (1.1%). 6. The treatment of aplaatic anemia consisted of blood transfusion, anabolic-androgenic steroid, adrenal corticosteroid hormone, and conservative or symptomatic management.