Spike Train Decoding에 기반한 인공와우 어음처리기의 음성시작점 정보 전달특성 평가

김두희,김진호,김경환,Kim, Doo-Hee,Kim, Jin-Ho,Kim, Kyung-Hwan 대한의용생체공학회 2007 의공학회지 Vol.28 No.5

The adaptation effect originating from the chemical synapse between auditory nerve and inner hair cell gives advantage in accurate representation of temporal cues of incoming speech such as speech onset. Thus it is expected that the modification of conventional speech processing strategies of cochlear implant(CI) by incorporating the adaptation effect will result in considerable improvement of speech perception performance such as consonant perception score. Our purpose in this paper was to evaluate our new CI speech processing strategy incorporating the adaptation effect by the observation of auditory nerve responses. By classifying the presence or absence of speech from the auditory nerve responses, i. e. spike trains, we could quantitatively compare speech onset detection performances of conventional and improved strategies. We could verify the effectiveness of the adaptation effect in improving the speech onset representation characteristics.

Neural Spike Train Decoding에 기반한 인공와우 어음처리방식 성능평가

김두희,김진호,김경환,Kim, Doo-Hee,Kim, Jin-Ho,Kim, Kyung-Hwan 대한의용생체공학회 2007 의공학회지 Vol.28 No.2

We suggest a novel method for the evaluation of cochlear implant (CI) speech processing strategy based on neural spike train decoding. From formant trajectories of input speech and auditory nerve responses responding to the electrical pulse trains generated from a specific CI speech processing strategy, optimal linear decoding filter was obtained, and used to estimate formant trajectory of incoming speech. Performance of a specific strategy is evaluated by comparing true and estimated formant trajectories. We compared a newly-developed strategy rooted from a closer mimicking of auditory periphery using nonlinear time-varying filter, with a conventional linear-filter-based strategy. It was shown that the formant trajectories could be estimated more exactly in the case of the nonlinear time-varying strategy. The superiority was more prominent when background noise level is high, and the spectral characteristic of the background noise was close to that of speech signals. This confirms the superiority observed from other evaluation methods, such as acoustic simulation and spectral analysis.

상수도(上水道) 페놀오염으로 인한 노출-비노출(露出-比露出) 지역주민(地域住民)의 호소증상(呼訴症狀) 비교(比較)

김두희,이성국,천병렬,이덕희,홍성철,장봉기,Kim, Doo-Hie,Lee, Sung-Kook,Chun, Byung-Yeol,Lee, Duk-Hee,Hong, Sung-Chul,Jang, Bong-Ki 대한예방의학회 1993 예방의학회지 Vol.26 No.2

A accidental spills of phenol(100%) to the river Nakdong with subsequent contamination of the tap water fer about two million consumers in Taegu city of Korea were occurred in March 1991. A historical cohort study of 6,913 individuals was undertaken to determine the associated with illness. Population subjects were divided into two groups of exposed and unexposed. Exposed subjects were reported to be phenol associated symptoms significantly higher than those in a nearby unexposed area(39.6% vs 9.4%, p<0.01). Especially, in the related symptoms, highly significant differences were noted in the number of subjects reporting gastrointestinal illness such as nausea, vomiting, diarrhea, or abdominal pain. During the accident, study subjects who experienced peculiar taste or odor in the tap water were significantly higher in the exposed areas(92% vs 34.3%). Chlorophenols formed from chlorination of water may have aggravated the problem. 지난 1991년 3월 16일 대구지역에서 발생한 상수도 페놀오염이 인체에 미치는 영향을 조사하기 위해 대구지역의 상수도 공급분포와 초 중 고등학교 지역적 분포를 비교하여 대상학교 10개교를 선정하여 이를 폭로군과 비폭로군으로 나누어 학생들의 가족구성원 전체를 대상으로 하여 설문지를 통하여 자기기입법으로 조사하였다. 분석내용은 노출지역과 비노출지역에서의 증상호소의 차이, 음용수 유형의 변화형태 등이다. 노출지역과 비노출지역에서 수도물만 먹은 사람을 비교하였을 때 페놀의 영향으로 볼 수 있는 증상으로 노출지역에서 3배 이상의 호소율을 나타낸 증상은 구역질, 구토, 설사, 복통, 두통, 입 목이 따끔거림, 피부증상으로 나타났다. 유관증상을 한가지 이상 호소한 경우는 노출군이 비노출군보다 약 3.5배(39 9% 대 9.4%)였으며 의료기관 이용율은 노출군에서 18.5%인 반면 비노출군에서는 4.7%로 약 4배의 차이를 보였다. 유관증상은 노출정도가 심할 수록 호소율이 높아지는 용량-반응 현상을 나타내었다. 그리고 이번 사건이후 생수. 혹은 약수를 찾거나 정수기를 설치하는 가구가 늘어났음을 관찰할 수 있었다. 노출지역에서 사건 전에 65.4%를 차지하던 수도물 사용이 페놀확인 후 32.2%로 떨어졌으나 비노출군에서는 57%에서 46.2%로 떨어졌다.

두발중 미량 중금속과 필수금속의 과다 또는 과소의 불균형과 폭력범죄 행동과의 관련성 연구

김두희,장봉기,이덕희,홍성철,김병희,Kim, Doo-Hie,Jang, Bon-Ki,Lee, Duk-Hee,Hong, Sung-Chul,Kim, Byung-Hie 대한예방의학회 1994 예방의학회지 Vol.27 No.1

To estimate the factors to the inclination of the criminal violence, the content of trace minerals and toxic metals in the scalp hair were measured during the period from May 1992 to October 1992. One hundred eleven violent and 89 nonviolent criminal inmates of Taegu Correctional Institute were selected. The inmates of violent criminals were imprisoned by murder, robber, rape, injury and violent acts. Those of nonviolent criminals were swindle, larceny, and adultery and had no history of institutional violence. The contents of two toxic metals (cadmium, lead) and five trace minerals (Cu, Fe, Zn, Mg, Na) were determined by an atomic absorption spectrophotometer (IL. 551). The contents of cadmium and lead in hair of violent criminals were significantly higher as $0.56{\pm}0.14ppm,\;11.53{\pm}3.32ppm$, respectively, than $0.42{\pm}0.20ppm,\;9.63{\pm}4.31ppm$ of nonviolent group (p<0.01). But the level of copper was significantly lower than nonviolent group (p<0.05). The factors that had a significant correlation with the inclination of violence in multiple logistic regression analysis were cadmium (odds ratio=98.09), unmarried (odds ratio=0.39), many times of criminal history(odds ratio=1.57) and residence of rural area (odds ratio=0.44). The results suggest that the sub-toxic contents of cadmium and lead in the hair may be of potential effect on behavior, and the mineral analysis may be an important adjunctive diagnostic procedure. Further studies into this problem are necessary. 어떤 금속성분의 과다 또는 과소가 폭력성향에 영향을 미치는 지를 분석하고자 1992년 5월부터 1992년 10월까지 대구교도소에 수감된 사람중 형이 확정된 남자 재소자로서 폭력범죄자(살인, 강도, 강간, 상해, 폭력 행위 등과 같은 폭력범죄로 구형 받은 사람 또는 이와 같은 폭력범죄의 전과가 있는 사람) 111 명과 비폭력 범죄자(사기, 절도, 도로교통법 위반, 간통 등과 같은 범죄로 구형받은 사람이면서 폭력범죄의 전과가 없는 사람) 89명, 총 200명을 대상으로 두발중 독성 중금속인 카드뮴 및 납과 필수금속인 아연, 구리, 철, 마그네슘 및 나트륨 함량을 원자흡광분광광도계 (IL, 551)로 분석하였다. 두발중 카드뮴과 납 함량은 폭력범죄자군에서 각각 $0.56{\pm}0.14ppm,\;11.53{\pm}3.32ppm$으로 비폭력범죄자군의 $0.42{\pm}0.20ppm,\;9.63{\pm}4.31ppm$보다 유의하게 높은 함량을 나타냈으나(각각, p<0.01), 구리 함량은 폭력군이 $9.07{\pm}3.85ppm$으로 비폭력군의 $10.53{\pm}5.82ppm$ 보다 유의하게 낮았다 (p<0.05). 다중지수형 회귀분석 결과 폭력성향과 관련되는 요인으로 카드뮴 함량(odds ratio=98.09)이 높을 수록, 미혼인 경우(odds ratio=0.39), 전과(odds ratio=1.57)가 많을 수록, 거주지역(odds ratio=0.44)이 농촌인 경우에 더 폭력적인 성향을 보이는 것으로 나타났다.

페놀오염사건 이후의 낙동강수 오염평가

김두희,장봉기,홍성철,문효정,이덕희,오혜주,Kim, Doo-Hie,Jang, Bong-Ki,Hong, Sung-Chul,Moon, Hyo-Jung,Lee, Duck-Hee,Oh, Hae-Ju 대한예방의학회 1993 예방의학회지 Vol.26 No.2

The aquatic quality of the Naktong river after two or three months in June, 1991 with phenol spillage from a electrical factory in Kumi was investigated. The samples were collected at six sites of the Naktong river basin and Kachang and Kongsan lakes. Phenol was not detected from all water samples. Turbidity was very much increased to the down stream in the Naktong river. The BOD and COD values exceeded the 2nd grade(3mg/l) of the Korean standard quality of Environmenal Water Act at the all sampling sites of the Naktong river. Especially, the value of COD at Kaejin (12.5mg/l) was poorly classified as to the 5th grade of water class for the environmental quality standards. Organophosphorous pesticides such as parathion, malathion, fenitrothion and diazinon were investigated but not detected. Diazinon was only detected at the Ilsan bridge(1.42ppb), Okkye stream(6.95ppb), Waekwan bridge(0.32ppb), Gangjung reservior(0.13ppb), Kaejin (0.05ppb). Of the carbamates such as carbanyl, isoprocarb and cabofuran, the carbofuran was detected all sites except tap water, and Kachang and Kongsan lakes. The content of heavy metals such as Cd, Pb, Zn, Fe, Mn, Hg were not exceeding for drinking water standards at the all sampling region, but only mecury was detected from Okkye stream(0.018ppb) and Kaejin (0.09ppb). In the regions of Kachang and Kongsan lakes, the content of heavy meatals were lower than that of reservior of Naktong river.

해독요법 중 커피관장을 적용한 죽상경화증의 치험 1례

김두희 ( Doo Hee Kim ),신우석 ( Woo Suk Shin ),정현우 ( Hyun Woo Jung ),정준교 ( Jun Kyo Jung ),이진원 ( Jin Won Lee ),박원형 ( Won Hyung Park ),차윤엽 ( Yun Yeop Cha ) 한방재활의학과학회 2013 한방재활의학과학회지 Vol.23 No.2

This study was performed to report the effect of coffee enema among detoxification Therapy on atherosclerosis.Russian patient was treated by coffee enema, acupuncture, herbal medicines, exercise, cupping, korean physical therapy, chuna manipulation treatment and moxibustion. The state of patient was measured by Infrared Thermography, Blood Vessel Stasis Test and Minnesota Nicotine Withdrawal Scale.After treatments, both feet temperature were increased. And index of indicating the occlusion of the lower body was improved. Also, Minnesota Nicotine Withdrawal Scale scores were improved. It means the patient was successful at non-smoking during hospitalization. These results suggests that atherosclerosis was improved. According to above results, coffee enema was effective to improve the atherosclerosis. More studies should be followed.

일본인의 모 한방병원 체험에 관한 분석

김두희(Doo Hee Kim),이동은(Dong Eun Lee),김형길(Hyung Kil Kim),조웅희(Woong Hee Cho),홍선기(Sun Gi Hong),최은주(Eun Ju Choi),유준상(Jun Sang Yoo),박원형(Won Hyung Park),차윤엽(Yun Yeop Cha),이선구(Seon Goo Lee),이우천(의료경영학과) 한의병리학회 2011 동의생리병리학회지 Vol.25 No.5

만성 요통 임상연구에 사용된 설문지 현황 고찰

김두희 ( Doo Hee Kim ),신우석 ( Woo Suk Shin ),이진원 ( Jin Won Lee ),박원형 ( Won Hyung Park ),차윤엽 ( Yun Yeop Cha ),고연석 ( Youn Seok Ko ),이정한 ( Jung Han Lee ),정원석 ( Won Suk Chung ),신병철 ( Byung Cheul Shin ),송윤경 ( 한방재활의학과학회 2013 한방재활의학과학회지 Vol.23 No.4

ObjectivesThe aim of this review is to provide fundamental data for low back pain scales which can be used in clinical trial.MethodsWe investigated the latest studies on chronic low back pain via PubMed. And we also investigated domestic studies through “http://oasis.kiom.re.kr”. 95 research pa-pers were analyzed. Scales were classified into pain scale, function scale, generic health status scale and psychological scale.Results1) According to foreign clinical studies, Visual Analog Scale (VAS) and Numerical Rating Scale (NRS) were used 18 times as pain scale. Oswestry Disability Index (ODI) was used 20 times as function scale, Roland-Morris Disability Questionnaire (RMDQ) was 17, and Hannover Functional Ability Questionnaire (HFAQ) was used 3 times. 36-item Short Form Health Survey (SF-36) was used 13 times as generic health status scale, Euroqol-5 Dimentions Questionnaire (EQ-5D) was 11, and 12-item Short Form Health Survey (SF-12) was used 3 times. Fear-Avoidance Beliefs Questionnaire (FABQ) was used 9 times as psy-chological scale, Pain Catastrophizing Scale (PCS) and Tampa Scale for Kinesiophobia (TSK-R) both were used 3 times. 2) According to domestic clinical studies, VAS was used 37 times as pain scale, NRS was 11, and Short Form McGill Pain Questionnaire (SF-MPQ) was used 6 times. ODI was used 30 times as function scale, RMDQ was 2 times only. SF-36 was used once as generic health status scale and Beck’s Depression Inventory (BDI) was used 3 times as psychological scale.ConclusionsWe recommend VAS or NRS as a measure to evaluate pain, and ODI as a measure to evaluate functional disability. And we also recommend SF-36 or SF-12 and EQ-5D as a measure to evaluate generic health status. Finally, we recommend FABQ for use in measuring psychological scale. (J Korean Med Rehab 2013;23(4):95-115)

비만 치료 한약 무작위 대조 임상시험에서의 음식 섭취량과 운동량 실태분석

김두희 ( Doo Hee Kim ),신우석 ( Woo Suk Shin ),박원형 ( Won Hyung Park ),차윤엽 ( Yun Yeop Cha ),송윤경 ( Yun Kyung Song ),안민윤 ( Min Youn Ahn ),고성규 ( Seong Gyu Ko ) 한방비만학회 2013 한방비만학회지 Vol.13 No.2

The objective of this study was to analyse the methods being used to control food intake and physical activity in RCTs of human obesity. Methods: A total of 21 randomized controlled trials (RCTs) were investigated. Nine of which were domestic studies from "http://oasis.kiom.re.kr" and the other of which were foreign studies from systematic reviews of RCTs on herbal medicine for treatment of human obesity. Results: According to domestic studies, "low calorie diet" were recommended in five cases of the domestic studies , "maintain current dietary habit" were recommended in two and no information on diet was two. Considering the seven cases where the information on diet was available, patients`` food intake were checked at every visit in six cases. Only two cases among the six had been dropped owing to the violation of dietary habit by patients. Exercises were prohibited in two cases, "maintain current level of phisical activity" were recommended in three cases and, from the rest, no information was available. The level of physical activity were not strictly controlled by any means hence no drop out. According to foreign studies, "low calorie diet" were recommended in two cases, "very low calorie diet (less than 700 kcal/day)" in one case, "maintain current dietary habit" in two cases, "do not eat fat" in two cases and no information was available in the rest five cases. Exercises which concerns spending about 300 kcal/day was recommended in one case, "moderate exercise" were recommended in three cases, "maintain current level of physical activity" were recommended in three cases and no information available in the rest five cases. Conclusions: In order to improve the accuracy of RCT, for the dietary side, researchers should record patient food intake at every visit by means of 24-hour dietary recall methods. This can be supplemented by multiple choice survey that are designed to help patients to diagnose themselves more accurately leading to less bias. For the exercise side, it is highly recommended to confine the exercises to walking only so as to quantify the amount of physical activity more easily by using pedometer.

자연재해저감종합계획 비구조적 대책의 안전취약계층도 작성방안에 관한 연구

김두희(Doo Hee Kim),송인재(In Jae Song),김병식(Byung-Sik Kim) 한국방재안전학회 2023 한국방재안전학회 논문집 Vol.16 No.1

방재분야의 최상위 계획인 자연재해저감종합계획은 지방자치단체별 시행하여 현재 2차계획이 수립중이며, 인명 및 재산피해를 최소화 하고자 9개 재해유형별 구조적 대책과 비구조적 대책을 수립하여 10년간 시행하는 계획이다. 구조적대책은 공학적근거와 정략적 분석기법으로 저감대책의 판단기준이 명확한 반면, 비구조적 대책의 판단기준은 미비된 실정이며, 재난 및 안전관리 기본법에서는 2018년 안전취약계층을 포함하였고, 자연재해저감종합계획 세부수립기준의 안전취약계층은 어린이, 노인, 장애인을 포함하여 수립 중이나 지자체의 자료확보 및 DB구축의 미비등 저감대책 수립을 위한 위치도 작성에 어려움을 초래하고 있다. 따라서, 본 연구에서는 안전취약계층의 오픈API 자료를 수집하여 통계지리정보서비스의 통계정보와 GIS를 활용하여 시범지역인 강원도 삼척시의 안전취약계층의 위치도를 작성하였고, 삼척시 근덕면의 집계구 단위 위치도를 작성하였다. The comprehensive natural disaster reduction plan, the highest plan in the disaster prevention field, was implemented by local governments. second plan is currently being formulated. In order to minimize human and property damage, structural and non-structural measures for each of the nine disaster types are established and implemented for 10 years. Structural measures are based on engineering and quantitative analysis, and the criteria for setting reduction measures are clear. Non-structural measures, however, currently lack the set criteria. the basic disaster and safety management law included the safety vulnerable class in 2018. Currently, the safety vulnerable class of the detailed establishment criteria of the comprehensive natural disaster reduction plan is being established, including children, the elderly, and the disabled. However, due to the lack of data securing and database construction by local governments, it is difficult to prepare a location map for establishing reduction measures for the safety vulnerable. Therefore, in this study, OPEN API data of the safety vulnerable class were collected and statistical information and GIS of SGIS information services were used. The distribution diagram of the safety vulnerable class in Samcheok, Gangwon-do, which is a sample area, and the distribution diagram of the safety vulnerable class in units of the output area (OA) in Geundeok-myeon were prepared.