박하의 항알레르기 활성

김대근,신태용,Kim, Dae-Keun,Shin, Tae-Yong 한국생약학회 1998 생약학회지 Vol.29 No.3

Antiallergic activity of the aqueous extract of Menthae herba (MHAE) was investigated in mice and rats. MHAE inhibited systemic anaphylaxis induced by compound 48/80 in mice. Especially, MHAE inhibited compound 48/80 induced systemic anaphylaxis 100% with a dose of 500 mg/kg body weight. MHAE significantly inhibited serum histamine levels induced by compound 48/80. MHAE inhibited histamine release from the rat peritoneal mast cells activated by compound 48/80 or anti-DNP IgE. Our studies provide evidence that MHAE will be beneficial in the treatment of anaphylaxis.

3.4급 알칼로이드의 검출에 의한 현호색의 확인

김대근,김기덕,엄동옥,Kim, Dae-Keun,Kim, Ki-Duck,Eom, Dong-Ok 한국생약학회 1999 생약학회지 Vol.30 No.1

A method using coloric and spectrophotometric detection have been developed for the identification of the tertiary or quaternary alkaloids contained in Corydalis tuber and its preparations. The principle is based on the formation or decomposition of complex compounds. The complex compound of the tertiary and quaternary alkaloids have been formed by adding tetrathiocyanatocobaltate [II] ion to the test soln. Diverse crude drugs were screened using this method and the results indicated that isoquinoline, aconitine-type alkaloids in crude drugs can be readily detected. The method is simple, convenient, reproducible and applicable to the verification of the crude drug Corydalis tuber and its preparations.

진범의 식물화학적 성분

김대근,곽종환,송기원,권학철,지옥표,이강노,Kim, Dae-Keun,Kwak, Jong-Hwan,Song, Ki-Won,Kwon, Hack-Cheol,Zee, Ok-Pyo,Lee, Kang-Ro 한국생약학회 1996 생약학회지 Vol.27 No.1

Four steroids and one flavonol glycoside were isolated from the ethanol extract of the whole plant of Aconitum pseudolaeve var. erectum. Their structures were identified as ${\beta}-sitost-4-en-3-one$, 22-dihydro-stigmast-4-en-3,6-dione, ${\beta}-sitosterol$, ${\beta}-sitosterol-3-O-{\beta}-D-glucopyranoside$ and $kaempferol-3-O-{\beta}-D-glucopyranoside(astragalin)$ on the basis of spectral data.

산수유의 반응성 산소종 생성 증진 성분

김대근,곽종환,류정희,권학철,송기원,강삼식,이성행,이은아,권년수,이강노,지옥표,Kim, Dae-Keun,Kwak, Jong-Hwan,Ryu, Jung-Hee,Kwon, Hak-Chul,Song, Ki-Won,Kang, Sam-Sik,Lee, Sung-Haeng,Lee, Eun-Ah,Kwon, Nyoyn-Soo,Lee, Kang-Ro,Zee, Ok-Pyo 한국생약학회 1996 생약학회지 Vol.27 No.2

Hydrogen peroxide is one of major chemicals mediating antitumor and antimicrobial activities of macrophages. We searched natural products enhancing hydrogen peroxide generation from murine macrophage-like cell line J774. Among 21 methanol extracts of Korean medicinal plants, the extract from Cornus officinalis was the most effective. The active component from the fractions was searched by activity guided fractionation, and identified as ursolic acid by spectral data.

관리회계관점에서 EVA의 활용에 관한 연구

김대근(Dae-Keun Kim),정창모(Chang-Mo Jung) 숭실대학교 사회과학연구소 2005 사회과학논총 Vol.7 No.-

기업의 가치측정 또는 경영자 및 사업부 성과를 평가하기 위하여 당기순이익, 주당순이익(EPS), 자기자본이익률(ROE) 등을 주로 사용하고 있다. 그러나 이러한 지표들은 회계가 갖는 고유한 문제점으로부터 자유롭지 못하며 기업의 자금조달 방법이나 회계처리의 방법에 따라 달라질 수 있기 때문에 기업이나 사업부의 진정한 부(wealth)의 창출규모를 파악하는데 한계가 있다. 전통적인 회계처리를 통해 구한 이익위주의 지표가 갖는 한계점을 인식한 미국의 경영컨설팅 회사인 Stern Stewart & Co.는 경제적부가가치(EVA : Economic Value Added)라는 지표를 개발하여 기업과 학계로부터 많은 관심을 받고 있다. 현행 손익계산서의 당기순이익은 자본비용 중 타인자본에 대한 이자비용만을 차감한 수치임에 반하여 EVA는 자기자본비용까지 차감함으로써 효과적인 기업평가와 경영진의 의사결정시 자기자본에 대한 기회비용까지 포함하고 있다. 최근 국내기업들도 대기업을 중심으로 앞다투어 EVA를 도입하고 있으며 증권거래소에서는 매년 상장기업의 EVA를 계산하여 공표하고 있다. 그러나 국내기업의 EVA 활용실태나 연구는 주로 재무회계적 관점에서 이루어지고 있다. 이 연구는 EVA의 본질을 주로 관리회계의 관점에서 다루고 있으며 우리나라의 EVA관련 연구의 검토 및 EVA의 활용실태를 조사하고 국내기업의 EVA 유용성 제고를 위한 활용상의 방안을 제시하고 있다. 국내기업의 EVA 활용상의 특징을 관리회계적 관점에서 살펴보면 구조조정수단으로의 활용, 내부경영성과평가 및 보수결정에의 활용, 경영혁신 및 원가절감수단으로의 활용 등을 들 수 있다. 국내기업이 EVA를 성공적으로 도입하기 위해서는 성과평가지표로서 EVA의 한계를 정확히 인식하고, 임직원들에게 기초적 재무개념의 이해와 EVA 도입을 위한 교육 및 훈련이 필요하며, 사업부 업적평가를 위한 세후영업이익(NOPAT)과 사업부문별 자본비용의 결정방법을 명확히 하여야 한다. 또한 EVA는 ABC, BSC와 동일한 조직 안에서 함께 사용함으로써 성과측정 및 가치창조경영을 위한 유인을 제공할 수 있다. Traditionally, we have used net income, earnings per share (EPS) and return on equity (ROE) as tools for the valuation of a company as a whole or for the performance evaluation of CEOs or business units. However, these measures have its own limitations in showing how much wealth was produced by an enterprise or a business unit since the measures are not free from the embedded problems of financial accounting itself and are subject to change by the financing methods or accounting practices of a company. Recently, a US consulting firm, Stem Stewart & Co. attracted attentions from many companies and academics when the firm developed a new measure called 'Economic Value Added' (EVA). While the traditional net income (NI) in the income statement is considering only the cost of the borrowed capital, the EVA enables managers to consider also the opportunity cost of equity capital when they measure the ultimate performance of a company or a business unit. Now, many of Korean companies are in the boom of adopting the EVA and the Korea Stock Exchange (KSE) announces the EVA of listed companies annually. While the applications of EVA by Korean companies and researches are primarily related with financial accounting perspectives, the major purposes of this study are introducing the nature of the EVA in terms of the managerial accounting perspective and providing suggestion to enhance the applicability of EVA for Korean companies. The characteristics in the utilization of EVA by Korean companies in terms of the managerial accounting perspectives can be summarized as follows; utilization as a tool for corporate restructuring, as a performance measure for business-units and incentive compensation, as an instrument for management innovation and cost reductions. In the process of employing the EVA system for managerial purpose, it is essential for Korean companies to consider the limitations of EVA as a performance measure. Korean companies also need to educate the employees so that they can understand the basic concepts of financial management and EVA. It is also critical for the purpose of performance evaluation of business-units to clearly define the method of determining the net operating profit after taxes (NOPAT) and the cost of capital. By adopting with activity-based accounting (ABC) and the balanced scorecards (BSC) at the same time in an organization, EVA system can provide the incentives for the true value creation and appropriate performance measure.

신종금융사기범죄의 실태 분석과 형사정책적 대응방안 연구

김대근(Kim, Dae-keun),임석순(Im, Seok-soon),강상욱(Kang, Sang-wook),김기범(Kim, Ki-bom) 한국형사법무정책연구원 2016 형사정책연구원 연구총서 Vol.- No.-

법경제학의 학적 필연성과 개념화에 대한 고찰

김대근 ( Dae Keun Kim ) 안암법학회 2011 안암 법학 Vol.0 No.34

Law and economics have been basic structure of human and society for a long time from Aristotles to many comtemporary researchers. Especially Luhmann, Habermas and Marx made an exercise to analyze and explain the structure of society in terms of law and economics. In modern times, individual came to be a central one in history compared with medieval times, and rationality has been divided into the political from the economic things. In this research, I try to show how individual came into being and rationality developed in a way that has been typed in a literary work such as the Odyssey(Homeros) and Robinson Crusoe(Daniel Defoe). The former shows us how individual be freed from nature and the latter how individual come to be economized. This typological Approach to character in literary works can help us to understand the meaning and function of law. In this perspective, law is an incentive to individual by inducing them to behave in specific ways. Law and Economics is a kind of interdisciplinary research using economic method to analyze and explain the legal things. Actually, economics has been considered to obtain the advantage over other social sciences of precision in analyzing human behavior and no other social sciences has a comparable objective basis for assessing individual subjective values and analyzing their behavior in the world. Anyway, it is true that law and economics have the same ultimate goal-to maximize social welfare-but disagreement arises with the effort to define and measure social welfare. Therefore it needs some steps to consider Law and Economic as a department of jurisprudence. For law, economic feasibility such as efficiency never acts as the sole determinant of social welfare. In order to take Law and Economic as a department of jurisprudence, economic feasibility should function to criticize legal theory and also to guarantee validity of law.

쉬땅나무 지상부의 Lignan

김대근(Dae Keun Kim),은재순(Jae Soon Eun),임종필(Jong Pil Lim),이강노(Kang Ro Lee),지옥표(Ok Pyo Zee) 대한약학회 1999 약학회지 Vol.43 No.3

Two lignans, (+)-8-hydroxypinoresinol (compound 1) and (-)-Olivil (compound 2), were isolated together with betulin (compound 3) from the aerial parts of Sorbaria sorbifolia var. stellipila Max. (Rosaceae). Their structures were characterized by physicochenlical and spectral means.

한국 코미디영화 형성기의 담론분석

김대근(Kim, Dae-Keun) 동국대학교 영상미디어센터 2016 씨네포럼 Vol.0 No.25

본 논문은 1950년대 후반 한국 코미디영화의 형성기에 등장한 코미디영화인 〈청춘쌍곡선〉(1957), 〈오부자〉(1958), 〈자유결혼〉(1958), 〈백만장자가 되면〉(1959), 〈여사장〉(1959), 〈홀쭉이 뚱뚱이 논산 훈련소에 가다〉(1959)에 대한 담론분석이다. 분석방법은 푸코가 제시한 담론분석방법을 사용하였다. 분석을 위해 각 영화가 드러내고 있는 담론을 추출하였고 그러한 담론이 만들어지는 외재적인 조건에 대하여 탐구하였다. 이를 통해 ‘대립적 관계의 반영과 결혼을 통한 갈등의 해소’, ‘미국으로 상징화된 서구화의 욕망’, ‘반공으로 표현된 국가체제의 완성’이라는 담론을 내포하고 있는 것으로 나타났다. 이러한 담론은 1950년대 한국사회의 역사적 상황을 반영하고 있으며, 일부는 당대의 권력의지와 지배이데올로기를 담아내고 있음을 알 수 있었다. 그럼으로써 코미디 영화의 현실 전복적 성격이 매우 제한되어 있음을 보게 되었다. This article attempts to critically analyze the discourses of six Korean comedy films 〈Hyperbolae of Youth〉 (1956), 〈Obuja〉 (1958), 〈The Love Marriage〉 (1958), 〈To be a millionaire〉 (1959), 〈A female boss〉 (1959), 〈A dry-bones and a fatty go to the Nonsan training station〉 (1959) produced during the late 1950s. By applying Foucauldian discourse methodology to the films, the selected comedy films are analyzed as discursive formation, which emerged within the existing social context of the concerned era; the actors’ dialogues are analyzed as statement which justified the Cold War ideology. It is demonstrated that the comedy films are forms of representation, which implies ‘the reflection of hostile relationship and the settlement of conflict through marriage’, ‘the desire for westernization represented by Americanism’, and ‘the completion of state system supported by anticommunism’ of the time. This discourse reflect historical situation of 1950s" Korean society, and also shows the contemporary will to power and the ruling ideology.

소아 급성위장염 환아의 Rotavirus감염에 관한 연구

김대근 ( Dae Keun Kim ),이주섭 ( Joo Sup Lee ),박기순 ( Ki Sun Park ),윤현정 ( Hyun Jung Yun ) 대한임상검사과학회 1984 대한임상검사과학회지(KJCLS) Vol.16 No.1

Rotavirus was detected in 357(30.5%) of 1, 170 Pediatric inpatients with acute gastroenteritis during the study performed from March 1982 to December 1983. The incidence of rotavirus gastroenteritis was highest in November (63.0%) and was lowest in June (9.4%). The seasonal variation of rotavirus gastroenteritis was significantly high in Autumn (44.4%). The most prevalent age group was 6 to 24 months (88.3%), while the age over 36 months showed the lowest rate (3.8%). The ELISA was as sensitive as electron microscopy for detection of rotavirus.