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김대근,황건,Kim, Dae-Geun,Hwang, Gun 한국수자원학회 2012 한국수자원학회논문집 Vol.45 No.3
댐 붕괴 직후에 댐 붕괴 근역에서의 댐 붕괴파 및 댐 붕괴파로 인한 하상변동을 추적하기 위하여 RANS를 지배방정식으로 하는 FLOW-3D를 이용한 3차원 수치모의를 수행하였다. 특히 이동상에서의 하상변동과 그 하상변동으로 인한 홍수파의 변동을 고정상에서의 해석결과와 비교하였다. 그 해석 결과를 정리하면 다음과 같다. 첫째, L자형 실험수로에서의 홍수파 해석 및 이동상 실험수로에서의 홍수파와 하상변동 해석 결과는 해당 수리실험을 만족스럽게 재현하고 있다. 둘째, 부유사의 농도는 홍수파의 전면에서 가장 높은 값을 보이며, 하상침식은 흐름이 급변하는 댐 직하류 지점에서 가장 크게 발생한다. 수로의 상류에서 발생하는 부유사로 인해 하류에서는 침식과 퇴적이 번갈아서 발생한다. 홍수파가 도달하는 초기에는 L자형 만곡부의 내측에서 침식이 우세하게 발생하나, 시간이 지나며 침식은 점차 만곡부의 외측으로 이동하는 양상을 보인다. 셋째, L자형 이동상에서의 홍수파는 하상의 침식 및 퇴적으로 인해 고정상에서의 홍수파에 비해 그 전파가 지체되며 홍수위가 크게 상승한다. We conducted a three-dimensional numerical simulation by using the FLOW-3D, with RANS as the governing equation, in an effort to track the dam-break wave.immediately after a dam break.in areas surrounding where the dam break took place as well as the bed change caused by the dam-break wave. In particular, we computed the bed change in the movable bed and compared the variation in flood wave induced by the bed change with our analysis results in the fixed bed. The analysis results can be summarized as follows: First, the analysis results on the flood wave in the L-shaped channel and on the flood wave and bed change in the movable-bed channel successfully reproduce the findings of the hydraulic experiment. Second, the concentration of suspended sediment is the highest in the front of the flood wave, and the greatest bed change is observed in the direct downstream of the dam where the water flow changes tremendously. Generated in the upstream of the channel, suspended sediment results in erosion and sedimentation alternately in the downstream region. With the arrival of the flood wave, erosion initially prove predominant in the inner side of the L-shaped bend, but over time, it tends to move gradually toward the outer side of the bend. Third, the flood wave in the L-shaped channel with a movable bed propagates at a slower pace than that in the fixed bed due to the erosion and sedimentation of the bed, leading to a remarkable increase in flood water level.
김대근,곽종환,류정희,권학철,송기원,강삼식,이성행,이은아,권년수,이강노,지옥표,Kim, Dae-Keun,Kwak, Jong-Hwan,Ryu, Jung-Hee,Kwon, Hak-Chul,Song, Ki-Won,Kang, Sam-Sik,Lee, Sung-Haeng,Lee, Eun-Ah,Kwon, Nyoyn-Soo,Lee, Kang-Ro,Zee, Ok-Pyo 한국생약학회 1996 생약학회지 Vol.27 No.2
Hydrogen peroxide is one of major chemicals mediating antitumor and antimicrobial activities of macrophages. We searched natural products enhancing hydrogen peroxide generation from murine macrophage-like cell line J774. Among 21 methanol extracts of Korean medicinal plants, the extract from Cornus officinalis was the most effective. The active component from the fractions was searched by activity guided fractionation, and identified as ursolic acid by spectral data.
김대근,곽종환,송기원,권학철,지옥표,이강노,Kim, Dae-Keun,Kwak, Jong-Hwan,Song, Ki-Won,Kwon, Hack-Cheol,Zee, Ok-Pyo,Lee, Kang-Ro 한국생약학회 1996 생약학회지 Vol.27 No.1
Four steroids and one flavonol glycoside were isolated from the ethanol extract of the whole plant of Aconitum pseudolaeve var. erectum. Their structures were identified as ${\beta}-sitost-4-en-3-one$, 22-dihydro-stigmast-4-en-3,6-dione, ${\beta}-sitosterol$, ${\beta}-sitosterol-3-O-{\beta}-D-glucopyranoside$ and $kaempferol-3-O-{\beta}-D-glucopyranoside(astragalin)$ on the basis of spectral data.
김대근,신태용,Kim, Dae-Keun,Shin, Tae-Yong 한국생약학회 1998 생약학회지 Vol.29 No.3
Antiallergic activity of the aqueous extract of Menthae herba (MHAE) was investigated in mice and rats. MHAE inhibited systemic anaphylaxis induced by compound 48/80 in mice. Especially, MHAE inhibited compound 48/80 induced systemic anaphylaxis 100% with a dose of 500 mg/kg body weight. MHAE significantly inhibited serum histamine levels induced by compound 48/80. MHAE inhibited histamine release from the rat peritoneal mast cells activated by compound 48/80 or anti-DNP IgE. Our studies provide evidence that MHAE will be beneficial in the treatment of anaphylaxis.
김대근,김기덕,엄동옥,Kim, Dae-Keun,Kim, Ki-Duck,Eom, Dong-Ok 한국생약학회 1999 생약학회지 Vol.30 No.1
A method using coloric and spectrophotometric detection have been developed for the identification of the tertiary or quaternary alkaloids contained in Corydalis tuber and its preparations. The principle is based on the formation or decomposition of complex compounds. The complex compound of the tertiary and quaternary alkaloids have been formed by adding tetrathiocyanatocobaltate [II] ion to the test soln. Diverse crude drugs were screened using this method and the results indicated that isoquinoline, aconitine-type alkaloids in crude drugs can be readily detected. The method is simple, convenient, reproducible and applicable to the verification of the crude drug Corydalis tuber and its preparations.
버뮤다그래스 페어웨이에 퍼레니얼라이그래스 오버시딩에 따른 두 초종의 밀도 및 품질 변화와 Trifloxysulfuron-sodium 처리에 의한 전이시기 조정
김대근,전재만,오상익,심규열,Kim, Dae-Gun,Jen, Jae-Man,Oh, Sang-Ik,Shim, Gyu-Yul 한국잔디학회 2012 한국잔디학회지 Vol.26 No.2
When perennial ryegrass was overseeded in bermudagrass fairway, shoot density of perennial ryegrass was gradually increased to $88,000/m^2$ at the end of May, however dramatically decreased to 0 in September over the rainy season. On the other hand, that of bermudagrass increased from $2,000/m^2$ in March to $20,000/m^2$ in early June, and then decreased to $4,000/m^2$ at the end of July, after the rainy season, rapidly increased to $50,000/m^2$ in early September. Overseeding bermudagrass fairway with perennial ryegrass was maintained a good quality from mid-April to mid-June and decreased the quality over the rainy season from late June to July, and then turf quality was decrease to the worst level at the end of July. After the rainy season fairway quality was improved gradually and was the highest-level during September and early October. Trifloxysulfuron-sodium was treated to minimize the deterioration in turf quality due to early bermudgrass transition time in spring. Consequently, transition was started in mid-May and shoot density of bermudagrass treated by trifloxysulfuron-sodium was $70,000/m^2$ in mid-June. Even in the rainy season it was sustained as $30,000/m^2$, approximately three times higher than that of untreated overseeding fairway. 버뮤다그래스에 퍼레니얼라이그래스를 오버시딩 했을 때 퍼레니얼라이그래스의 밀도는 3월부터 점차적으로 증가하여 5월 말에는 88,000주/$m^2$를 유지하였다. 그러나 장마기를 거치면서 급격히 줄어들어 9월 초순경에는 0주/$m^2$가 되었다. 반면에 버뮤다그래스의 밀도는 3월경에 2,000주/$m^2$에서 온도가 증가함에 따라 점차 증가하여 5월 중순경에 10,000주/$m^2$, 6월 초순경에는 20,000주/$m^2$로 증가하였으며, 장마기를 거치면서 일조량 부족으로 7월 중순경에는 4,000주/$m^2$로 떨어졌다. 장마 후에는 밀도가 급격히 증가하여 9월 초순경에는 50,000주/$m^2$ 정도를 유지하였다. 퍼레니얼라이그래스로 오버시딩한 버뮤래스 페어웨이의 품질은 4월 중순부터 6월 중순까지 좋은 품질이 유지되다가 장마기이후 7월말에 가장 나빴으나 이후 점차 향상되어 9월 초순부터 10월 초순까지 좋은 품질을 나타내었다. 봄철 버뮤다그래스의 전이시기를 앞당겨 장마기의 품질저하를 최소화하기 위하여 trifloxysulfuron-sodium을 처리한 결과, 5월중순경부터 버뮤다그래스로 전이가 이루어져 6월 중순경에는 70,000주/$m^2$ 정도의 밀도를 보였으며 장마기에도 약 30,000주/$m^2$를 유지하여 무처리구에 비하여 약 3배 이상의 높은 밀도를 유지하였다.