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김경욱,김종우,황의완,김현택,박순권,이정륜 대한한방신경정신과학회 2000 동의신경정신과학회지 Vol.11 No.2
Background : The aim of this study was to evaluate the effect of Punsimgieumgamibang on insomnia and anxiety. which is widely used in mental diseases. Method : We admitted Punsimgieumgamibang into rats which illumination of the sleeping periodhas been reversed, and measured its activity rate during the sleeping period. Also we studied the effect of Punsimgieumgamibang on anxiety using analyses of Punsimgieumgamibang on anxiety using analyses of behavior of rats submitted to the elevated plus-maze test. Result : 1) The sleeping ratio of the Pusimgieumgamibang group was higher than the control group on the whole, and the difference of the groups in the third time block was significant statistically. 2) We could not find any statistical information in all of the 4 anxiety related behavior of the elevated plus-maze experiment. and there was a tendency to a higher measurement in the Punsimgieumgamibang group animals in the total arms visitation in the elevated plus-maze, open arms visitation, and the amount of time of stay in arms. Conclusion : It is suggested that Pusimgieumgamibang has effects on insomnia. 1