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조민정,기세국,황윤진,윤영국,이수경 대한외과학회 2003 Annals of Surgical Treatment and Research Vol.65 No.4
Heterotopic mesenteric ossification is a very uncommon disorder that is characterized by new bone formation in the mesentery, which does not normally undergo ossification. A 52-year-old female experienced a small bowel obstruction 12 days after a segmental resection of the small bowel following a trauma. A laparotomy was performed 16 days after the initial operation, and a 2 cm hard mass was detected in the small bowel mesentery, with severe fibrous adhesions around the mass, involving the jejunum, which required resection. Postoperatively, the patient developed an intraabdominal abscess, followed by intestinal fistulation. The patient gradually recovered by conservative management, and left hospital 70 days after the first operation. Microscopic examination of the mass showed well oriented trabeculae of the osseous tissue, osteoid formation, with fine calcification and osteoblastic activity, but there was no formation of mature lamellar bone or clear evidence of the "zone phenomenon" that is classically described in heterotopic ossification. These findings appeared consistent with an early stage of heterotopic ossification. The etiology and pathogenesis are unknown; the heterotopic mesenteric ossification was thought to be associated with the trauma (intraabdominal surgery). The previous literature on heterotopic mesenteric ossification is reviewed, and a new case reported. (J Korean Surg Soc 2003;65:361-365)
버거씨 병 환자에서 Lipo-prostaglandin E1 정맥 주사의 치료 효과
김영욱,기세국 대한혈관외과학회 1998 Vascular Specialist International Vol.14 No.2
To observe the therapeutic effects of iv Lipo-prostaglandin E1 for the patients with Buerger's disease, 16 patients presenting severe peripheral ischemic symptom were enrolled and prospectively assessed the efficacy of Lipo-PGE1 after 4 weeks of iv bolus injection of Lipo-PGE1. Pain relief, reduction of ulcer size, change of ankle brachial index and change of toe pressure measured with photoplethysmography were assessed as end points of therapeutic efficacy. After 4 weeks of treatment, 69.2% of patients revealed pain relief, 33.3% revealed reduction of ulcer size (>50%), 18.8% revealed increased ankle brachial index (>0.15), and 18.8% revealed increased toe pressure. The side effects of iv bolus Lipo-prostaglandin E therapy was minimal.