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      • KCI등재

        Two new b-carboline alkaloids from the stems of Picrasma quassioides

        권현숙,이한나,이진수,이기준,최정혜,장대식 대한약학회 2018 Archives of Pharmacal Research Vol.41 No.5

        Two new b-carboline alkaloids, 1-acetyl-4-methoxy-8-hydroxy-b-carboline (1) and 1-acetyl-4,8-dimethoxy-b-carboline (2), together with 10 known compounds;seven b-carboline alkaloids (3–9), two canthin-6-one alkaloids (10 and 11), and one quassinoid (12) wereisolated from the stems of Picrasma quassioides. Thestructure of the new compounds 1 and 2 were determinedby spectroscopic analyses including 1D- and 2D-NMR andHRMS interpretation. All the isolates (1–12) were evaluatedfor their cytotoxicity against human ovarian carcinomaA2780 and SKOV3 cell lines using MTT assays. Ofthe isolates, compounds 5–7 exhibited the most potentcytotoxicity on both A2780 and SKOV3 cell lines in vitro.

      • KCI등재

        청소년 인터넷 게임 관여와 중독 차원에 따른 중독의 발달단계 연구: 잠재계층 분석을 통한 단계구분과 관련 변인의 역할

        권현숙,권경인 한국청소년상담복지개발원 2017 청소년상담연구 Vol.25 No.1

        본 연구는 청소년의 인터넷 게임사용에서 일반적인 과다사용이 점진적으로 어떻게 중독 행위로 진행되는지를 탐색하고, 그 과정에서 심리적 보호요인과 위험요인은 무엇인지를 확인하고자 하였다. 이를 위해 인터넷 게임 이용자들의 병리적이지 않은 긍정적 측면과 병리적인 요인을 각각 분리하고 관여와 중독으로 정의하였다. 자료는 서울, 경기 일부지 역의 PC방에서 인터넷 게임을 이용하는 청소년 207명을 대상으로 표적 표집한 것이다. 연구 결과, 인터넷 게임 중독의 변화 양상이 심각도를 반영하여 6개 잠재계층으로 분류 되었다. 분류된 잠재계층에서 중관여-고중독 집단은 병리적 수준의 중독집단이고, 고관 여-저중독, 고관여-중중독, 고관여-고중독 집단은 중독의 심각도가 반영된 인터넷 게임 과다사용 집단임을 변별하였다. 그리고 관여와 중독의 경향성 분석을 통해서 일반적인 과다사용이 중독으로 진행되는 과정을 제시하고, 그 과정에서 병리적 수준의 중독을 진 단하는 변별점을 확인하였다. 각 잠재계층과의 영향요인을 검증한 결과, 충동성은 중독 집단을 가장 잘 설명하는 위험요인이고 기본심리욕구의 자율성은 인터넷 게임 중독의 치료적 개입을 위한 보호요인으로 평가하였다. 본 연구의 내용은 DSM-5에서 추가 연구 가 필요하다고 분류된 인터넷게임장애(Internet addition disorder)에 대한 것이다. The purpose of this study was to explore how adolescents' internet gaming addictive behavior had been gradually developed and what the protective factors and risk factors were during the process. For the study, the non-pathological online gamers is defined as engagement; their pathological factors are defined as addiction. The data were collected from 207 adolescents, who played online games at PC room in Seoul and Gyeong-gi areas. Which were consist of target sample. The major results of analysis were as follows. The groups of online game users including the researchers were categorized into 6 latent classes. Among the 6 latent classes, the intermediate engagement-high addiction can be interpreted as the group in need of clinical treatment; high engagement-low addiction, high engagement-intermediate addiction and high engagement-high addiction can be viewed as the group of internet game over-users based on the severity of addiction. And it was confirmed the boundary point between the internet gaming over-use and internet gaming disorder The finding of this study is meaningful in that it explored the process of internet gaming over-use proceeding to internet gaming disorder, which was identified as a condition warranting more clinical research and experience according to DSM-5.

      • 직업유무에 따른 여성의 화장만족에 관한 연구

        권현숙 경산대학교 보건복지연구소 2000 保健福祉硏究 Vol.5 No.-

        A study on mid-aged women's mental satisfaction with face make-up in Taegu area was conducted in order to figure out health-related factors on the psycho-social approach to face make-up culture, such as acquisition of social support, degree of self-esteem, obsessiveness caused by face make-up culture, self-directed assertiveness through face make-up behavior, mobile activeness after face make-up, dependence on face make-up and fashion sensitivity in face make-up, and in order to signify these factors with respect to health promotion concept so that Face Make-up Behavior can be related into factors for Health Promotion Model Theory recently issued and enlightened worldwide. In this study, the vocational status of mid-aged women was mainly focused and a comparison of mental satisfaction factors above-stated between career women vs housewives was made and reviewed Five hundred and seven (507) women who were aged between 30 to 45 had been selected randomly and questionnaires were exposed for collecting the related information. The questionnaire also included general characteristics survey, to which added were questions on self-estimated health state, and dieting status. 1. Both parts in the age group of 30's and 40's were commonly high in the factors of dependence on face make-up, mobile activeness after face make-up, and self-directed assertiveness through face make-up behavior. 2. Make-up behavior on the part of career women was related more with body shape, health status, and degree of self-esteem. 3. Make-up behavior on the part of housewives was related more with self-directed assertiveness through face make-up behavior, and obssessiveness caused by face make-up culture. The research show that the career women tend to be health-promoted by face make-up behavior more in physical way than in psychological way. On the other hand, the housewives tend to be health-promoted more in psychological way such as make-up fashion obssessiveness and self-directed assertiveness. Further studies on make-up culture and the related fashion effect on the health promotion in mid-aged women's make-up behavior are thought to be necessary and better to be conducted with each group separately.

      • KCI등재

        플라톤의 『국가론』에 나타난 ‘자기다움’의 청소년교육적 의미 고찰

        권현숙,이광호 한국청소년학회 2015 청소년학연구 Vol.22 No.12

        Today the teenagers lose sight of the significance of 'selfhood', largely because of a tendency to believe that others would be their own self images. The crisis of education begins with the failure to recognize the central role of selfhood in adolescent education. This research aims at filling the gap the absence of selfhood, through elucidating the connection between 'selfhood' and happy life in Plato's Republic. This research will bring light on the role of selfhood in adolescent education through an hermeneutic interpretation of Plato's Republic. Plato argues that the union of the soul which is divided into appetite, spirit, and reason should be harmonized to keep life happy. The harmony of the soul can be achieved by being kept in balance temperance, courage, and wisdom. To obtain such stability, contends Plato, learning justice or righteousness becomes central along with search for selfhood. Who am I? What makes us happy? The answer to these questions depends on knowing what would be worthwhile for life. Knowing about his or her self can be served as the basis for selfhood which is in turn rooted in concern for solicitude. It is my conclusion in the research that the search for selfhood in Plato's philosophy will provide an opportunity to re-think our school systems which concentrate on competition and lack of personality. My contention implied here is that contemporary education should be paid attention to selfhood which focuses on the development of their own potentiality through the liberation of their own prejudices. It should be based on an anthropological project for finding out our hidden capabilities for human happiness. 오늘날 청소년들은 ‘자기다움’의 의미를 상실한 채 학업성취에 따라 타인을 ‘자기화’시키는 경향이 많다. 청소년교육의 위기는 ‘자기다움’을 찾아야 하는 교육의 부재에서 기인한다고 볼 수 있다. 본 연구는 플라톤의 『국가론』에 나타나는 조화로운 삶을 위한 ‘자기다움’의 교육과 행복한 삶의 연관성을 밝히고, ‘자기다움’의 현대적 청소년교육의 의미를 텍스트 해석학적 방법을 통해 분석해 이를 해석하고자 한다. 플라톤이 주장하는 ‘조화로운 삶’은 욕망, 기개, 이성 등 세 부분의 영혼이 절제, 용기, 지혜의 탁월함을 갖추어 화합을 이루는 것이다. 조화로운 영혼을 위한 교육은 ‘올바름’의 교육이며, ‘자기다움’의 교육이다. ‘자기다움’을 알기 위해서 필요한 것은 내가 누구인지, 무엇을 할 때 행복한지를, 그리고 내가 가치 있게 생각하는 것이 무엇인지를 아는 것이다. 결국 ‘자기다움’은 ‘자기인식’과 연결되며, ‘자기인식’은 ‘자기배려’와 관련이 있다는 점에서 행복한 삶과 연관성이 있다. 이런 의미에서 플라톤의 ‘자기다움’을 찾는 교육은 서로의 경쟁을 부추기는 파편화된 개인을 양산하는 현대 학교교육이 지향해야하는 방향을 제시해준다. ‘자기다움’을 찾는 현대 청소년교육은 인간 영혼의 해방이며, 행복한 삶을 살기 위해 자신의 자질을 찾는 ‘인간학적’과정이다.

      • KCI등재

        Research on the Quality of Life of the Parents by Functions, Activities, Participation, and Environmental Factors of Children with Cerebral Palsy Using ICF-CY Checklist

        권현숙,손성민 대한물리치료학회 2018 대한물리치료학회지 Vol.30 No.1

        Purpose: This study examined whether the quality of life of parents of children with cerebral palsy is affected by the functions, activities, participation, and environmental factors using an ICF-CY check list. Methods: This study recruited in 26 parents of children with cerebral palsy. The functions, activities, participation, and environmental factors of the children were evaluated using ICF-CY checklist. To measure the quality of life of parents, this study used world health organization quality of life (WHOQOL-BREF), which was composed of a total of 26 questions. The GMFCS (gross motor function classification system) was used to assess the degree of disability in the children. Multiple regression analysis was performed to examine the effects of the ICF-CY checklist on the quality of life. Correlation analysis was performed to examine the correlation between GMFCS and WHOQOL. Results: The functions, activities, participation, and environmental factors were significantly different from WHOQOL-BREF. On the other hand, the contextual factor showed a significant difference in the neuromusculoskeletal and movement-related functions (b7), and service, systems, and policies (e5)(p<0.05). Conclusion: This study suggests that the functions and environmental factors affect the quality of life of parents of children with cerebral palsy. Therefore, these findings suggest that contextual factors, such as neuromusculoskeletal and movement-related functions (b7), and service, systems and policies (e5), which can be facilitators, should be considered for improving the quality of life of parents of children with cerebral palsy.

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