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Effect of Exercise on Cystatin C as a Risk Factor for Renal Failure and Hypertension
권유찬,박상갑,박현태,김은희,박진기,장재희 한국운동영양학회 2012 Physical Activity and Nutrition (Phys Act Nutr) Vol.16 No.1
This study was conducted to investigate the effect of a 24-week combined exercise training program in older women with hypertension. Women with hypertension who were 70 years and older were randomized into two groups: combined exercise group (CE; n = 15) and a control group (n = 15). The CE group performed a combined exercise training program four times per week for 24 weeks and the control group did not. Five factors, including body composition (percent body fat and skeletal muscle mass), health-related physical fitness, adipocytokines (interleukin-6 [IL-6] and tumor necrosis factor-alpha [TNF-α]), kidney risk factors (glomerular filtration rate [GFR] and cystatin C), and systolic and diastolic blood pressure were measured before and after the program. The findings showed that total muscle mass, health-related physical fitness factors, and GFR increased significantly in the CE group compared to those in the control. Additionally, systolic and diastolic blood pressure and IL-6, TNF-α, and cystatin C levels in the CE group decreased significantly after the intervention. In contrast, total muscle mass decreased significantly and blood pressure remained unchanged in the control group. These results suggest that CE training may positively impact circulating levels of adipocytokines and cystatin C and improve physical fitness levels in elderly women with hypertension. Therefore, CE training helps to prevent renal disease and improve health-related physical fitness, eventually leading to a better quality of life.
권유찬,김은희,곽병철,서정민,박상갑 東亞大學校附設스포츠科學硏究所 2003 스포츠科學硏究論文集 Vol.21 No.-
이처럼 면역과 관련되는 다양한 연구가 진행되어 왔지만 연구자들의 공통된 내용은 면역기능을 강화하기 위해서는 적절한 휴식이 들어가느 중등도의 운동을 지속적으로 하는 것이 가장 좋은 방법으로 알려지고 있다. 현재 사람들의 평균 수명이 점차고 증가하고 있으며, 저마다 well-bing 신드롬이 일고 있다. 이처럼 인간은 각자 삶의 질(QOL)을 높이기 위해서 노력하고 있으며, 앞으로 지속적인 운동과 면역에 관련한 연구가 진행되어 인류의 삶의 질을 높이는데 효과적인 운동처방이 이루어져야 할 것이다.
운동심리학 : 유산소와 근저항의 복합트레이닝이 비만 청소년의 림프구 및 TNF-a 농도에 미치는 영향
권유찬(KwonYoo-Chan),윤미숙(YounMi-Suk),박상갑(ParkSang-Kab) 한국체육학회 2003 한국체육학회지 Vol.42 No.2
The effects of exercise on immune function unclear. The purpose of this study was to investigate the changes of lymphocyte proliferation, NK cell and TNF-a concentration after 16weeks combined training. Subjects were composed of fourteen obese middle-school students. The training program was separated treadmill running and muscular resistance training. The treadmill running was composed of 60%HRmax, 30 minutes per day, 4 days per week. The muscular resistance training was composed of 60% of 1RM, 40 minutes per day, 4 days per week, 2-way repeated ANOVA was used to evaluate the difference among group and pre and post 16 weeks. The 0.05 level of significance was as critical level for the study.The body weight and %body fat were significantly decreased. And lean body mass and VO<sub>2</sub>max(㎖/㎏/min)was significantly increased after combined training. Also, lymphocyte proliferation and NK-cell were significantly increased after combined training. Both of TNF-α and IL-6 concentration were decreased. And insulin concentration were decreased after combined training.In conclusion, combined training was shown to positive influence on body composition, lymphocyte proliferation and NK cell. In particularly, decreased TNF-α and IL-6 concentration was affect insulin concentration. Therefore, it is maybe thought that combined training was important role for obesity treatment.