만성 중이염 175명 환자의 고실성형술에 의한 청력 결과

정용수,곽희붕,이여진,박문수,김재명,신정은,박홍주 대한이비인후과학회 2009 대한이비인후과학회지 두경부외과학 Vol.52 No.11

Background and Objectives To report the hearing results of tympanoplasty for chronic otitis media with or without cholesteatoma. Subjects and Method One hundred and seventy-five patients presenting chronic otitis media with or without cholesteatoma were involved in a retrospective study. Tympanoplasties were performed by the same surgeon over a 30-month period. Audiometric results were reviewed. Audiometric results according to the following techniques were measured: tympanoplasty type 1 (T1), interposition (Si) and/or columella (Sc) over stapedial head, and interposition or columella (Fic) over footplate. The follow-up period ranged from 6 to 32 months. Audiological parameters using the average of four frequencies were assessed pre- and post-operatively. Results Overall hearing results showed postoperative air-bone gaps (ABG) ≤20 dB in 69% of cases. ABG was closed to within 20 dB in 89% for T1, 67% for Sc, 58% for Si, and 30% for Fic. ABG was closed to within 30 dB in 95% for T1, 67% for Sc, 83% for Si, and 70% for Fic. There was a significant improvement between preoperative and postoperative ABGs. The overall improvement of the air-bone gap was 8±13 dB. There was no significant functional difference between different surgical techniques. Conclusion Our hearing results after tympanoplasties were similar to those from other studies. The hearing results observed in this study confirmed that successful results can be obtained by applying the current principles and approach to ossicular reconstruction.

보행시 이명이 유발되는 상반고리관피열증후군 1예

박가현,박홍주,곽희붕,이여진,문원진 대한이비인후과학회 2008 대한이비인후과학회지 두경부외과학 Vol.51 No.8

The superior canal dehiscence syndrome (SCDS) is a rare disorder caused by the dehiscence of the temporal bone overlying the superior semicircular canal. It has become apparent that SCDS can lead to a variety of clinical manifestations, vestibular and/or auditory, in contrast to the typical symptoms, as initially described. We recently examined a 54-year-old woman with unilateral stepsynchronous tinnitus without any vestibular symptoms. Tinnitus is a quite unremarkable finding among variable symptoms of the syndrome; however, it can be one of the clues to identify SCDS when it is accompanied by low-frequency conductive hearing loss. Therefore, in diagnosing SCDS, attention must be also paid to those patients with nonspecific complaints, for example, stepsynchronous tinnitus. (Korean J Otorhinolaryngol-Head Neck Surg 2008;51:738-41)

Tympanometry and CT Measurement of Middle Ear Volumes in Patients with Unilateral Chronic Otitis Media

안재윤,박홍주,박가현,정용수,곽희붕,이여진,신정은,문원진 대한이비인후과학회 2008 Clinical and Experimental Otorhinolaryngology Vol.1 No.3

Objectives. The goals of the study were to compare the middle ear (ME) volumes from both normal and lesioned ears, and these ME volumes were measured by a digital image processing computed tomography (CT) program in patients with unilateral chronic otitis media, and we wanted to compare the ME volumes of the lesioned ears by comparing the ME volumes obtained by tympanometry with those ME volumes measured by the digital image processing CT program. Methods. Forty-four patients who had unilateral chronic otitis media (COM) and contralateral normal tympanic membranes (TM) and 100 subjects with normal TMs were included in the study. The normal volumes of the external auditory canal (EAC) were measured in the normal group. The tympanometric ME volumes in the ears with a perforated TM were calculated as the difference of the tympanometric volumes measured from the both ears in patients with unilateral COM. The CT ME volumes were measured by a digital image processing program. Results. The tympanometric volumes of the EACs in the ears with normal TMs were 1.4±0.3 mL. There were no significant differences according to gender, age and the side of the face the ear was on. The tympanometric volumes of the EAC in the normal-side ear of the patients with unilateral COM showed no significant differences when compared with those from the normal group. The ME volumes of the intact ears, as measured by CT, showed significantly higher values than those ME volumes of the lesioned ears. The ME volumes of the lesioned ears, as measured by tympanometry, showed a strong, significant linear correlation with those ME volumes calculated by CT; however, the ME volumes of the lesioned ears, as measured by tympanometry (1.5±1.4 mL), were significantly larger than those ME volumes measured by CT (1.1±0.8 mL). Conclusion. Our results show that chronic otitis media causes reduced ME volumes compared to those ME volumes of the contralateral normal ears. Tympanometry can provide a valuable estimation of the ME volumes in chronic ears, although it tends to overestimate the ME volumes, and especially for the ears with a larger ME volume. Objectives. The goals of the study were to compare the middle ear (ME) volumes from both normal and lesioned ears, and these ME volumes were measured by a digital image processing computed tomography (CT) program in patients with unilateral chronic otitis media, and we wanted to compare the ME volumes of the lesioned ears by comparing the ME volumes obtained by tympanometry with those ME volumes measured by the digital image processing CT program. Methods. Forty-four patients who had unilateral chronic otitis media (COM) and contralateral normal tympanic membranes (TM) and 100 subjects with normal TMs were included in the study. The normal volumes of the external auditory canal (EAC) were measured in the normal group. The tympanometric ME volumes in the ears with a perforated TM were calculated as the difference of the tympanometric volumes measured from the both ears in patients with unilateral COM. The CT ME volumes were measured by a digital image processing program. Results. The tympanometric volumes of the EACs in the ears with normal TMs were 1.4±0.3 mL. There were no significant differences according to gender, age and the side of the face the ear was on. The tympanometric volumes of the EAC in the normal-side ear of the patients with unilateral COM showed no significant differences when compared with those from the normal group. The ME volumes of the intact ears, as measured by CT, showed significantly higher values than those ME volumes of the lesioned ears. The ME volumes of the lesioned ears, as measured by tympanometry, showed a strong, significant linear correlation with those ME volumes calculated by CT; however, the ME volumes of the lesioned ears, as measured by tympanometry (1.5±1.4 mL), were significantly larger than those ME volumes measured by CT (1.1±0.8 mL). Conclusion. Our results show that chronic otitis media causes reduced ME volumes compared to those ME volumes of the contralateral normal ears. Tympanometry can provide a valuable estimation of the ME volumes in chronic ears, although it tends to overestimate the ME volumes, and especially for the ears with a larger ME volume.

사골포 골점막 피판을 이용한 안와 내벽 골절의경비강 내시경적 정복술에 대한 임상적 고찰

조형철,김성윤,강무현,장민희,곽희붕,백준,이종원,최정섭 대한이비인후과학회 2006 대한이비인후과학회지 두경부외과학 Vol.49 No.7

Background and Objectives:Various surgical approaches have been employed to treat fractures of the medial orbital wall. Among them, the transnasal endoscopic approach provides the chance to avoid external scars and to observe the fracture site clearly. These approaches mostly require the use of grafts or splints. Authors carried out a retrospective study on the blowout fractures repaired by bulla ethmoidalis osteomucosal flap (BOMF) and compared them with the groups that were treated with silastic sheet only and with Med-pore to investigate the merits of BOMF with respect to results and complications. Subjects and Method: We reviewed 62 cases (64 sides) of medial wall fractures that were treated surgically. They were diagnosed with 3 mm facial CT scans and treated according to the authors’ indications from February 1998 to March 2004 at Namgwang Hospital, Seonam University. The surgical treatment consisted of the reconstruction of the fractures and the repair of the remaining bone defects by graft and splint, and the type of graft was selected according to the size of the defect. For minor defects, silastic sheet was used alone, whereas major defects were repaired with BOMF or Med-pore. All patients were evaluated regularly for at least six months postoperatively. Results:There were no differences in the aspects of the final treatment results of diplopia and enopthalmos. Butin the aspects of postoperative crust formation and granulation, the cases that were repaired with BOMF showed better results as well as the economic merits. In the BOMF cases, the average duration of silastic sheet stenting was 12.5 days and it could reduce the follow up period. Conclusion:BOMF demonstrated better results in the respects of duration of silastic sheet stenting, postoperative crust formation, granulation and economic cost. (Korean J Otolaryngol 2006;49:699-705)

Plateau 및 Rise/Fall 시간의 변화에 따른 안구전정유발근전위의 변화

이여진,한수희,하은정,정용수,곽희붕,박문수,신정은,박홍주 대한평형의학회 2008 Research in Vestibular Science Vol.7 No.2

Background and Objectives: The ocular vestibular evoked myogenic potential (OVEMP) is a recently discovered test of labyrinthine function, analogous to the cervical VEMP. Recent works have demonstrated the existence of OVEMPs, which likely reflect otolith-ocular reflex. The purpose of this study was to identify the optimal plateau and rise/fall times of short tone bursts to detect OVEMPs in healthy subjects. Materials and Methods: Thirteen healthy subjects (26 ears) were included in this study. Surface electromyographic activity was recorded from active electrodes placed inferior to each eye. Stimulation with 500 Hz short tone bursts was used. We used a variety of plateau and rise/fall times. Three different plateau times (1, 2, and 3 ms) and rise/fall times (0.5, 1, and 2 ms) were used. The incidence, amplitudes and latencies were compared. Results: VEMP responses were clearly observed in all 26 ears at the plateau time of 2 ms and two rise/fall times (0.5 and 1 ms). The amplitudes in the individual ears tested were lower at the rise/fall time of 2 ms than at the other conditions. The amplitudes were lower at the plateau time of 3 ms compared to the other conditions. When the rise/fall time was prolonged from 0.5 to 2 ms, the n1 and p1 latencies were prolonged in parallel. However, there was no such change in latencies according to the plateau times. Conclusions: Our findings show that the ideal stimulation pattern for evoking OVEMP is at the rise/fall times of 0.5 or 1 ms and the plateau time of 2 ms. The waveform morphology of the VEMP responses observed with this stimulation pattern was simultaneously the most constant and marked. Background and Objectives: The ocular vestibular evoked myogenic potential (OVEMP) is a recently discovered test of labyrinthine function, analogous to the cervical VEMP. Recent works have demonstrated the existence of OVEMPs, which likely reflect otolith-ocular reflex. The purpose of this study was to identify the optimal plateau and rise/fall times of short tone bursts to detect OVEMPs in healthy subjects. Materials and Methods: Thirteen healthy subjects (26 ears) were included in this study. Surface electromyographic activity was recorded from active electrodes placed inferior to each eye. Stimulation with 500 Hz short tone bursts was used. We used a variety of plateau and rise/fall times. Three different plateau times (1, 2, and 3 ms) and rise/fall times (0.5, 1, and 2 ms) were used. The incidence, amplitudes and latencies were compared. Results: VEMP responses were clearly observed in all 26 ears at the plateau time of 2 ms and two rise/fall times (0.5 and 1 ms). The amplitudes in the individual ears tested were lower at the rise/fall time of 2 ms than at the other conditions. The amplitudes were lower at the plateau time of 3 ms compared to the other conditions. When the rise/fall time was prolonged from 0.5 to 2 ms, the n1 and p1 latencies were prolonged in parallel. However, there was no such change in latencies according to the plateau times. Conclusions: Our findings show that the ideal stimulation pattern for evoking OVEMP is at the rise/fall times of 0.5 or 1 ms and the plateau time of 2 ms. The waveform morphology of the VEMP responses observed with this stimulation pattern was simultaneously the most constant and marked.

주시 방향에 따른 안구전정유발근전위의 변화 양상

이여진,한수희,하은정,안재윤,박가현,정용수,곽희붕,박문수,신정은,박홍주 대한이비인후과학회 2009 대한이비인후과학회지 두경부외과학 Vol.52 No.3

Background and Objectives:Recent works have demonstrated the existence of ocular vestibular evoked myogenic potentials (OVEMPs), which reflects otolith-ocular reflex. The purpose of this study was to identify an appropriate gaze position to detect OVEMPs produced by air-conducted sound stimulation in healthy subjects. Subjects and Method:Twenty four healthy subjects (35 ears) were included in this study. Surface electromyographic activity was recorded from active electrodes placed inferior to each eye. Stimulation with 500 Hz short tone bursts was used to activate the vestibular end-organs. Results:Sound stimulation evoked negative-positive biphasic responses on both ipsilateral and contralateral eyes, while responses were contralateral eye-dominant. Contralateral eye responses had higher response incidence and larger amplitudes. Altering the direction of gaze generally changed the incidence and size of the inter-peak amplitudes. The higher incidence and larger amplitudes were recorded when the eyes are directed to the superior and ipsilateral side to the sound stimulation. In that gaze position, the amplitude was 5.3 μV, the first negative peak latency was 10.5 ms and the following positive peak latency was 15.4 ms on the average. Conclusion: OVEMPs can be evoked using an air-conducted 500 Hz tone burst and are best recorded contralaterally with a upward gaze towards the source of sound stimulation. Further changes of the test parameters are needed for higher and consistent responses.

Results of Air Caloric and Other Vestibular Tests in Patients with Chronic Otitis Media

이인식,신정은,이여진,박홍주,정용수,곽희붕 대한이비인후과학회 2009 Clinical and Experimental Otorhinolaryngology Vol.2 No.3

Objectives. Air caloric results are supposed to be influenced by anatomic changes of the middle ear. The aims of our study were to evaluate the incidence and characteristics of abnormal air caloric results in patients with unilateral chronic otitis media and without any history of vertigo, and to compare caloric results with there of other vestibular function tests (VFTs). Methods. Twenty five patients with unilateral chronic otitis media (COM) who were scheduled for surgery underwent VFTs preoperatively. Hearing was assessed using pure-tone audiometry and vestibular function was assessed using a set of VFTs: air caloric, head-shaking nystagmus (HSN), vibration-induced nystagmus (VIN), and subjective visual vertical (SVV) tests. Results. Six patients (24%) showed pathologic canal paresis (CP) on COM-sided ears. Two patients showed pathologic CP on the contralateral side. However, both of the two showed inverted nystagmus to warm air stimulation on the COM-side and hyperactive nystagmus to cold air stimulation on the COM-side, which means that the COM-sided ear was stimulated too much. There was pathologic HSN in 12 patients (48%), pathologic VIN in 7 (28%), and pathologic SVV in 5 (20%). Overall, 20 (80%) patients showed abnormal findings through a set of VFTs. Patients with an interaural difference of bone-conduction hearing thresholds ≥10 dB tended to show more abnormal VFT results than those for whom the interaural difference of bone-conduction hearing thresholds was <10 dB. Conclusion. Our data show that one-fourth of patients with unilateral COM show abnormal caloric results on the COM side. However, subclinical latent vestibular imbalances were found to be common, which might be related to the gradual vestibular involvement in inflammatory processes, regardless of the caloric results. Results of a set of VFTs should be referred to when determining vestibular imbalance in patients with COM. Objectives. Air caloric results are supposed to be influenced by anatomic changes of the middle ear. The aims of our study were to evaluate the incidence and characteristics of abnormal air caloric results in patients with unilateral chronic otitis media and without any history of vertigo, and to compare caloric results with there of other vestibular function tests (VFTs). Methods. Twenty five patients with unilateral chronic otitis media (COM) who were scheduled for surgery underwent VFTs preoperatively. Hearing was assessed using pure-tone audiometry and vestibular function was assessed using a set of VFTs: air caloric, head-shaking nystagmus (HSN), vibration-induced nystagmus (VIN), and subjective visual vertical (SVV) tests. Results. Six patients (24%) showed pathologic canal paresis (CP) on COM-sided ears. Two patients showed pathologic CP on the contralateral side. However, both of the two showed inverted nystagmus to warm air stimulation on the COM-side and hyperactive nystagmus to cold air stimulation on the COM-side, which means that the COM-sided ear was stimulated too much. There was pathologic HSN in 12 patients (48%), pathologic VIN in 7 (28%), and pathologic SVV in 5 (20%). Overall, 20 (80%) patients showed abnormal findings through a set of VFTs. Patients with an interaural difference of bone-conduction hearing thresholds ≥10 dB tended to show more abnormal VFT results than those for whom the interaural difference of bone-conduction hearing thresholds was <10 dB. Conclusion. Our data show that one-fourth of patients with unilateral COM show abnormal caloric results on the COM side. However, subclinical latent vestibular imbalances were found to be common, which might be related to the gradual vestibular involvement in inflammatory processes, regardless of the caloric results. Results of a set of VFTs should be referred to when determining vestibular imbalance in patients with COM.