제42차 춘계학술대회 : 포스터 연제 ; 피하화농성 육아종

곽호,전수일 대한피부과학회 1990 초록집 Vol.28 No.20

노인복지시설의 동절기 실내 온열환경 평가에 관한 연구 : 대구광역시 소재 노인복지시설을 중심으로 focused in the welfare facilities for the aged in taegu

곽호,추연희,홍원화,이무진 대한건축학회 2001 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.21 No.1

뇌실외 배액 후 출혈한 수아세포종 : 증례보고 Report of 2 Cases

곽호신,정영섭,왕규창,조병규,한대희 대한신경외과학회 1994 Journal of Korean neurosurgical society Vol.23 No.4

The authors experienced 2 cases of medulloblastoma in which active hemorrhage occurred after external ventricular drainage(EVD). A 5 yeardd girl suffered from cerebellar fit and brain CT Scan showed severe hydrocephalus. So EVD was performed and the pressure was measured about 80cm H2O. After a gradual reduction of EVD pressure for 15 minutes, fresh blood gushed out through the EXD catheter. The other case was a 7 year-old girl whose tumor bled after intraoperative EVD, just before dural incision. Both tumors were highly vascular in operative field. The first case was ;)ed-ridden at 5 months after surgery and the second case was on postoperative chemotherapy in a good general condition with minimal neurological deficits. Previous reports in the literatures including 2 cases of hemorrhage associated with EVD in medulloblastoma were reviewed The relatively high incidence of tumor hemorrhage in medulloblastoma and its detrimental influence on the outcome are emphasized

장기 생존한 교모세포종 환자의 예후인자 분석

곽호신,황승균,김정은,백선하,김동규,정희원 대한신경외과학회 2002 Journal of Korean neurosurgical society Vol.31 No.1

Objectives:The authors analyze the clinical characteristics of the long-term survivors and elucidate the biological factors responsible for long-term survival. Methods:The 166 cases of histologically confirmed glioblastoma from Jan 1983 to Aug 1999 were included. Medical records and radiological findings were reviewed to analyze age, performance status, location and number of the tumor, the amount of peri-tumoral edema, the extent of surgical resection and history of radiation and/or chemotherapy. The overall survival was 13.6 months and the 1-year survival rate was 59%. The thirteen patients(6.9%), lived more than three years after diagnosis, defined as the long-term survivors. Results:Performance status(KPS≥70), number of masses(single with no CSF seeding), and hemispheric location(not involving basal ganglia and/or brain stem) showed favorable influence on the patient survival in univariate analysis. Also post-operative radiation and chemotherapy resulted in significant improvement of the survival. However, in multivariate analysis, age(under 40 years) was the most significant prognostic factor. All the other factors which was significant in univariate analysis except the location of the tumor, also verified as significant prognostic factors in multivariate analysis. The long-term survivors had at least more than five out of seven significant prognostic factors in multivariate analysis. And these factors occurred more frequently and showed significances in the long-term survivors than the other patient group except the debulking surgery. Conclusion:The age at the diagnosis and invasiveness resulted in multiple tumor and/or CSF seeding were the most significant prognostic factors. Key words:Glioblastoma;Long-term survivor;Age;Multifocal tumors.

시상부위에 발생한 단일성 뇌농양 : 증례 보고 및 문헌고찰 Report of Two Cases and Review of the Literature

곽호신,김동규,이상형,정희원,이현구,김현집,한대희 대한신경외과학회 1992 Journal of Korean neurosurgical society Vol.21 No.12

The authors present two cases of solitary thalamic abscess which were intially diagnosed as malignant thalamic glioma. After treatment with steroids and osmotic agents, the patients' clinical conditions improved after two to three days. However, sudden deterioration of consciousness level developed and the CT scan showed acute hydrocephalus with increment of thalamic low-density lesions. We performed extraventricular drainage and obtained CSF containing numerous inflammatory cells. This suggested the possibility that the lesion was a pyogenic abscess. which progressed to ventriculitis, rather than a malignant glioma. Stereotactic aspiration of the lesion confirmed thalamic abscess. These findings and review of previous reports of thalamic abscess suggested that early diagnosis and stereotactic drainage of the thalamic abscess is of primary importance.

Recent Advancements of Treatment for Leptomeningeal Carcinomatosis

곽호신,Sang Hyun Lee,박원서,Sang Hoon Shin,유헌,이승훈 대한신경외과학회 2015 Journal of Korean neurosurgical society Vol.58 No.1

Treatment of Leptomeningeal carcinomatosis (LMC) from solid cancers has not advanced noticeably since the introduction of intra-cerebrospinal fluid (CSF) chemotherapy in the 1970’s. The marginal survival benefit and difficulty of intrathecal chemotherapy injection has hindered its wide spread use. Even after the introduction of intraventricular chemotherapy with Ommaya reservoir, frequent development of CSF flow disturbance, manifested as increased intracranial pressure (ICP), made injected drug to be distributed unevenly and thus, the therapy became ineffective. Systemic chemotherapy for LMC has been limited as effective CSF concentration can hardly be achieved except high dose methotrexate (MTX) intravenous administration. However, the introduction of small molecular weight target inhibitors for primary cancer treatment has changed the old concept of ‘blood-brain barrier’ as the ultimate barrier to systemically administered drugs. Conventional oral administration achieves an effective concentration at the nanomolar level. Furthermore, many studies report that a combined treatment of target inhibitor and intra-CSF chemotherapy significantly prolongs patient survival. Ventriculolumbar perfusion (VLP) chemotherapy has sought to increase drug delivery to the subarachnoid CSF space even in patients with disturbed CSF flow. Recently authors performed phase 1 and 2 clinical trial of VLP chemotherapy with MTX, and 3/4th of patients with increased ICP got controlled ICP and the survival was prolonged. Further trials are required with newly available drugs for CSF chemotherapy. Additionally, new LMC biologic/pharmacodynamic markers for early diagnosis and monitoring of the treatment response are to be identified with the help of advanced molecular biology techniques.

老人福祉施設의 冬.夏節期 室內 溫熱環境 測定 및 溫熱感 評價

곽호,류우동,황광일,홍원화,Kwak, Ho,Ryoo, Woo-Dong,Hwang, Kwang-Il,Hong, Won-Hwa 한국주거학회 2003 한국주거학회 논문집 Vol.14 No.1

This study aims to survey the living spaces of the welfare facilities for the aged to get the objective relationships between the physical thermal environment and the users' subjective responses. The surveys were made twice in winter and once in summer during 2001 and 2002. An ambient temperature, relative humidity, air velocity, globe temperature were measured as physical elements of thermal environment and the ASHRAE Psychophysical Voting Scale were used as an evaluation index for subjective responses. As the results, the aged respond thermally comfortable, in spite of the differences among important factors such as thermal sensations, humidity sensations and air velocity sensations. Also the physical thermal environmental elements and the subjective responses indices exceed thermal comfort range calculated by PMV(Predicted Mean Vote) and PPD(Predicted Percentage Dissatisfied). It shows that the insulation of walls of the facilities is not enough for heating and cooling seasons, and the indoor environmental control is necessary.

Analyzing Activity for Estrus Detection in Korean Native Cattle

곽호,김기영,김동균,이상정 한국지식정보기술학회 2015 한국지식정보기술학회 논문지 Vol.10 No.2

Existing estrus detection products operation inconvenience, due to the reliability of the device degradation problems estrus detection probability is lower. In addition, most existing studies was the study of estrus detection of milk cows in large-scale farms studies on Korean Native Cattle farms was not realized. In this paper, discerned using a 3-axis accelerometer to determine the estrus state of Korean Native Cattle. The Korea Native Cattle estrus detection system proposed in this paper consists of these, the three-axis acceleration sensor, sensor network uses Zigbee communication, a base station, field server and database servers. When there is no movement the value of the three-axis acceleration sensor is 1000 due to gravity, the acceleration sensor attached to the cattle’s neck causes a feeble change even though there is no movement of cattle. In this paper, due to the no activity of Korean Native Cattle, censed weak values of sensor are filtered out. In the experiment the sensor data acquisition activities that occur during the actual targeting Cattles at the Cattle farmer by the three-axis acceleration sensor X, Y, Z-axis values analyzed through SVM algorithm output’s one representative value and ISVM algorithm which output integral average. In addition, to determine Korean Native Cattle’s estrus time, activity data collected and compared by 3 hours, 6 hours integral. ISVM algorithm was validated by experimental results that the appropriate algorithm for the Korean Native Cattle’s activity analysis.

음성 데이타 처리를 위한 데이타베이스 검색 언어의 설계 및 구현

곽호신,박영배 명지대학교 공학기술연구소 1990 공학기술연구소 논문집 Vol.5 No.-

Various problems of speech database system were discussed and a new logical structure of speech database was presented. To handle the speech data, variable length data must be processed as well as fixed length data. A new retrieval language for speech data was presented. This query style language can be used to analyze speech, and the embedded retrieval language retrieve phonemes of arbitary speech pattern. The tool was implemented using C Language on IBM-PC/386 and could be used for speech data retrieval.

삼차신경통과 반측 안면 경련에 대한 미세혈관 감압술의 단기성적

곽호신,정천기,김현집,오창환,정영섭,김동규,정희원,최길수,한대희 대한신경외과학회 1994 Journal of Korean neurosurgical society Vol.23 No.4

The result of microvascular decompression (MVD) in 105 consecutive cases is presented. The symptomatic vasculoneural compressions including tumor, vascular malformation, or aneurysm are excluded in this study group. The 41 patients with trigeminal neuralgia (TN) were all treated by posterior fossa exploration (PFE). Eighteen of them were treated with MVD only, another 14 with partial sensory rhizotomy (PSR) only, and in the other 9 patients, MVD and PSR were performed together. Sixty-two of 64 hemifacial spasm (HFS) cases were treated succesfully with MVD via PFE. However in one case of which the offending vessel was not identified, neurolysis was camed out. The other case who had both TN and HFS, died due to intraoperative cardiac arrest The result of operation was evaluated at one month after the operation. In TN, among thirty-nine (98%) patients who resulted in pain-improvement, 32 (82%) experienced complete resohition of the pain.,The rate of complete pain-relief was higher in the 'MVD only group' than in 'group with PSR': Amomg 62 (94%) cases of HFS, 29 (47%) patients obtained 'complete cure' and 'improvement-only' respectively only 4 (6%) patients had no change of the spasm. The preoperative clinical characteristics, intraoperative surgical fingdings and postoperative outcomes were itemized and analyzed to find out the prognostic factors. The our results are compared with others in the literature.