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광화학적 허혈성 뇌졸중 모델에서 사심탕(瀉心湯)의 뇌세포 손상 보호효과
강백규,윤종민,문병순,Kang, Baek-Gyu,Yun, Jong-Min,Moon, Byung-Soon 대한한방내과학회 2012 大韓韓方內科學會誌 Vol.33 No.4
Objectives : This study was designed to investigate the effects of Sasim-tang (SST) on proinflammatory cytokine production in a photothrombotic ischemia mouse model. Methods : Photothrombotic ischemia was induced in stereotactically held male Balb/c mice using rose bengal (10 mg/kg) and cold light. The target of photothrombotic ischemic lesion was 1 mm anterior to bregma and 3 mm lateral to midline with 2 mm in diameter, which are decreased by oral administration of SST. Results : SST protected ischemic death of brain cells through inhibition of pro-inflammatory cytokines production and catalytic activation of caspase-3 protease in photothrombotic ischemia mouse model. Conclusions : The results of this study suggest that SST can have protective effects on brain cell damage in a photothrombotic ischemia mouse model.
식적(食積) 및 음허(陰虛)로 인한 해수 환자의 임상적 특성 분석
이정욱,박상무,강백규,한덕진,나란희,방창호,장석오,손지우,이시형,Lee, Jung-Wook,Park, Sang-Moo,Kang, Baek-Gyu,Han, Deok-Jin,Na, Ran-Hee,Bang, Chang-Ho,Jang, Seak-Oh,Son, Ji-Woo,Lee, Si-Hyeong 대한한방내과학회 2009 大韓韓方內科學會誌 Vol.30 No.1
Cough is a common clinical problem to which various etiologies are attributable. In Korean medicine there are differentiations in etiology such as food-accumulation and Yin-deficiency. This study was aimed to analyze the relations between the time of cough and Korean syndrome differentiations and to compare the symptoms of Korean syndrome differentiations (food-accumulation and Yin-deficiency). Sixty-two cough patients were analyzed and classified into one of two syndrome differentiations by etiology. We compared the time of coughing and symptomatic characteristics of two: such as symptom differences and change of severity after treatment. Patients with food-accumulation were more prevalent than patients with Yin-deficiency. Among symptoms, anorexia, dyspepsia, nausea and nasal discharge were more prevalent in food-accumulation while pruritus of throat was prevalent in Yin-deficiency. Coughing at night was prevalent in Yin-deficiency and coughing at rising hour was prevalent in food-accumulation.
중풍 환자의 사상체질 유형별 혈중지질 분포에 대한 상관성 연구
이민구,박세욱,손지우,김대중,강백규,박상무,이인,문병순,이선우,Lee, Min-Goo,Park, Sae-Wook,Son, Ji-Woo,Kim, Dae-Joong,Kang, Baek-Gyu,Park, Sang-Moo,Lee, In,Moon, Byung-Soon,Lee, Sun-Woo 대한한방내과학회 2006 大韓韓方內科學會誌 Vol.27 No.2
Objectives : This study was executed in order to examine relationship between Sasang constitution and serum lipids in CVA patients. Method and Results : This study was done with 104 cases of stroke patients who admitted to department of the internal medicine Wonkwang university oriental hospital from September in 2004 to August in 2005. A study on the relationship among serum lipids : In T-cholesterol and triglyceride, T-cholesterol and HDL-cholesterol, LDL-cholesterol and HDL-cholesterol. T-cholesterol and LDL-cholesterol, they had positive correlation each other. Between triglyceride and HDL-cholesterol, they had negative correlation each other. Distribution of serum lipids which it follows in stroke type : T-cholesterol, HDL-cholesterol and LDL-cholesterol average of cerebral hemorrhage is higher than cerebral infarction. Distribution of serum lipids which it follows in Sasang constitution : T-cholesterol, triglyceride and LDL-cholesterol average of Taeyumin was higher than different types of Sasang constitution But it didn't have no statistically consideration Conclusions : The relationship between Sasang constitution and Serum lipids was not proven.
뇌졸중 환자의 하지 강직에 대한 음양경락별 전침의 효과
박세욱,이민구,이선우,강백규,손지우,박상무,이인,문병순,Park, Sae-Wook,Lee, Min-Goo,Lee, Sun-Woo,Kang, Baek- Gyu,Son, Ji-Woo,Park, Sang-Moo,Lee, In,Moon, Byung-Soon 대한한방내과학회 2006 大韓韓方內科學會誌 Vol.27 No.2
Objectives : The aim of this study is to review the effects of acupuncture on lower limb spasticity control in stroke patients. Methods: H-reflex/M-response ratio and Modified Ashworth Scale was used for evaluation of spasticity control before acupuncture, within one hours after acupuncture , at twenty-four hours, and four weeks. We divided two groups. One is the yin meridian acupunctured goup and the other is the yang meridian acupunctured group. Results: H/M ratio is declined within 1 or 24 hours after acupuncture for poststroke spasticity patients. The yin meridian acupunctured group is a bit more efficient than the yang meridian acupunctured goup. But there is no meaning in the statistics because of small patient pool. Conclusions: We need more patients group to decide the effect of electro- acupuncture on leg spasticity of stroke patients.