精神分裂症으로 移行한 Gilles de la Tourette氏 病의 1例 報告

황익근 中央醫學社 1975 中央醫學 Vol.29 No.6

A case of Gilles de la Tourette's disease transformed to schizophrenic psychosis is reported in this paper. The patient has been suffered from Gilles de la Tourette's disease for 17 years without any reasonable treatment. He has not any history of Rheumatic fever or Encephalitis in his earlier life. E. E. G. , Skull X-Ray, and other neurological examinations do not reveal any abnormalities. The disease seems to be psychogenic in its origin in the light of the free neurological findings. During the course of his illness lasting 17 years, his personality has become gradually changed and destroyed resulting in schizophrenic psychoses. The anther also suggested the psychodynamic formulation about the cause of schizo?phrenic personality change and Gilles de la Tourette's disease in this case. It seems to be ambiguous that the Gilles de la Tourette's disease has really become transformed to schizophrenic psychoses or they have different origins in their process progressing respectively.

Mescaline에 依한 Clonidine 效果의 中樞性 抉抗

黃翼根 전북대학교 의과학연구소 1980 全北醫大論文集 Vol.4 No.1

1. Antagonism of the intraventricular clonidine effect on blood pressure and heart rate by intraventricular mescaline was investigated in urethane-anesthetized rabbits. 2. Mescaline produced little effect on blood pressure, and produced slight decrease in heart rate. Clonidine produced distinct depressor and bradycardiac effects. 3. After mescaline administration, the depressor and bradycardiac effects of clonidine were markedly diminished and not observed, respectively. 4. The lowered blood pressure and the slowed heart rate by clonidine were heightened and temporalily increased by mescaline, respectively. 5. Intraventricular regitine did not affect the blood pressure response to mescaline but po-tentiated the decrease in heart rate by mescaline. 6. Methylatropine did not affect the decrease in heart rate by mescaline. 7. The results indicate that mescaline acts as an antagonist for the central α-adrenergic receptors. In addition mescaline may exert pulse-slowing effect of central origin

Introduction of Biofeedback

황익근 圓光大學校 醫科大學 神經精神科學敎室 1987 圓光精神醫學 Vol.3 No.2

정신분열증 환자의 친척에서 보인 표출된 감정

정영철,정애자,황익근 大韓神經精神醫學會 1988 신경정신의학 Vol.27 No.3

It has been reported that expressed emotion, a measure of family attitude toward psychiatric patients, is closely related to the relapse of schizophrenics. To test the above mentioned relationship, the authors evaluated expressed emotion of schizophrenic's relatives with six component scales; critical comment, hostility, dissatisfaction, warmth, emotional overinvolvement and guilt. The subjects consisted of three different groups ; relatives of 15 chronic schizophrenia, relatives of 15 subchronic schizophrenia and relatives of 15 neuroses who were admitted to the department of neuropsychiatry of Chonbuk Notional University Hospital. The results were as follows ; 1) 3 Groups were significantly different in frequencies of critical comment. In comparison of other expressed emotion, intensity of hostility and warmth also showed significant difference in all of the compared groups(Table 7). 2) Critical comment was positively correlated to hostility(r=0.93). But hostility was negatively related to warmth (r--0.49). 3) Comparing the high expressed emotion group with the similar studies of other countries, Korea vs California was significantly different at p<.05 X²and British vs California was also different with the statistical significance at p<.01. In addition the mean frequencies of critical comment was lowest in Korea among them.

한 작품에 나타난 주인공들의 Oedipus Complex : 유기수의 "끝나지 않는 처녀"를 중심으로 Focused on a Novel "Endless Virgin"

황익근 원광대학교 채문연구소 1996 역사와 사회 Vol.17 No.-

小兒 精神科 患者의 臨床的 硏究

黃翼根 전북대학교 의과학연구소 1981 全北醫大論文集 Vol.5 No.1

Clinical study was done for the child psychiatric patients who had been treated in the department of psychiatry, Jeonbug Medical School Hospital from 1975 to 1980. The results were as followings; 1. 14 percent of total psychiatric patients consisted of child psychiatric patients 2. Absolute number of child psychiatric patients has increased every year. 3. 75.2 percent of the total psychiatric patients belong to the age group between 12 and 16 years old. 4. Sex ratio for male and female was 1.6:1 5. 22.9 percent of the out-patients was neurosis, which was the highest among all of the disorders. 6. Neurosis(56.3%) psychosis(28.8%) and epilepsy(7.5%) were the major diseases in admitted patients. 7. 88.8 percent of the admitted patients belong to the puberty and early adolescent age group, and few patients were admitted under the age of 6.

Tridione 服用後 發生한 骨髓不全症의 1例

黃翼根 전북대학교 의과학연구소 1977 全北醫大論文集 Vol.1 No.-

An interesting case of bone marrow failure, which was caused by tridione, one of anti-epileptic drugs, has been reported in this paper. The changes of cellular elements in bone marrow and peripheral blood in relation to the toxicity of tridione on hematopoietic system have been reviewed briefly. Additionally, the effectiveness of combined therapy of testosterone and steroid to the case of bone marrow failure caused by tridione has been implied, and the clinical importance of regular blood examination to whom tridione is given has also been suggested.

일측 흑질체 및 복측피개 파괴 백서에서 도파민D₁ 효현제 및 도파민 D₂효현제가 회전운동에 미치는 영향

은홍배,유상은,임현규,황익근 大韓神經精神醫學會 1995 신경정신의학 Vol.34 No.5

To investigate the role dopamine D₁ and D₂ recepters on circling behavior, effects of SKF 38393 and LY 171555 were examined in rats with 6-OHDA-lesioned substantia nigra or in rats with 6-OHDA-lesioned ventral tegmentum. 1) In the rats with 6-OHDA-lesioned substantia nigra, SKF 38393, dopamine D₁ agonist, elicited contralatral rotation in a fraction of the lesioned animals(60)%, while LY 171555, dopamine D₂ agonist, elicited contralatral rotation in the entire animals. 2) In the rats with 6-OHDA-lesioned ventral tegmentum, SKF 38393 elicited contralatral rotation in a fraction of the lesioned animals, while LY 171555 elicited contralatral rotation in the entire animals. 3) In the rats which SKF 38393 induced contralatral rotation, circling offects of dopamine D₁ agonist and D₂ agonist in rats with 6-OHDA-lesioned substantia nigra were not different from those in rats with 6-OHDA-lesioned ventral tegmentum. 4) In the rats which SKF 38393 failed to induced contralateral rotation, the influence of dopamine D₁ agonist and dopamine D₂ agonist on the circling behavior in the rats with 6-OHDA-lesioned ventral tegmentum was signiricantly lower than that in the rats with 6-OHDA-lesioned substantia nigra. 5) In the rats which DKF 38393 failed to induce contralatral rotation, there was not priming effect in rats with 6-ODDA-lesioned ventral tegmentum but in rats with 6-OHDA-lesioned substantia nigra. From the above results, it is concluded that both dopamine D₁ agonist and D₂ agonist can elicit contralateral ratation in rats with 6-OHDA-lesioned ventral tegmentum as well as in rats with 6-OHDA-lesioned substantia nigra and that anatomical location of lesioned area is important for development of priming effect.

간질환자의 MMPI 반응

배철,황익근 大韓神經精神醫學會 1983 신경정신의학 Vol.22 No.4

저자는 간질환자의 MMPI반응을 알아 보고자 1982년 10월 1일부터 1983년 2월 28일 사이에 전북의대 부속병원 신경정신과의 시내 개인신경정신과의원에서 항경령제를 투여 치료받고 있는 외래환자 90명중 61명에게 MMPI를 실시하였던 바 다음과 같은 결론을 얻었다. 1. 환자군과 대조군에서 각 척도별 T-점수의 평균값은 정상범위 안에 있었다. 2. 전체 환자군과 대조군의 비교검증상에서 척도 F, Hs, D, Hy, Pa, Pt, Sc은 p<.01이고 척도 Pd, Ma은 p<.05로서 유의한 차이가 관찰되었다. 3. 형태분석 상에서 환자군 중 33.9%에서 정신과적진단을 붙일 수 있었고 대조군에선 1.6%에 정신과적 진단을 붙일 수 있었다. 4. 성별 비교에서 남녀 공히 신경증 척도(Hs, D, Hy)와 척도 Pt, Sc에서 유의하게 나타났으나 척도 F, Pa, Ma에서는 남자군에서 만이 유의한 차이가 관찰되었다. 5. 병력기간 별 비교에서는 5년 이하와 6년에서 10년 사이의 비교에서는 척도 F, Sc에서 유의한 차이가 관찰되었고 5년 이하와 11년 이상의 비교에서는 각각 척도Hy에서 유의한 차이가 관찰되었다. 6. 청소년기에 해당하는 환자군과 대조군의 비교에서는 척도 D에서 유의한 차이가 있었던 반면 초기성년기는 전 신경증 척도와 정신증 척도, 그리고 척도 F, Si에서 유의한 차이가 관찰되었다. 중기성년기에서 전 신경증 척도, 척도 F, Pt, Sc에서 유의한 차이가 관찰되었다. A clinical study was done on 61 epileptic patients to investigate MMPI responses of the patients, 126healthy subjects were used as control group. The results were as followings 1. Mean value of T-scores on each scale was within normal range in both patient and control group. 2. Pattern analysis indicated that psychiatric problems were recognized in 33.9% of patient group and in 1.6% of control group. 3. In patient group, scales of F, Hs, D, Hy, Pa, Pt and Se (p<. 01) as well as scale of Pd and Ma (p<. 05) were significantly higher than in control group. 4. In male group, scales of F, Pa, Ma were statically significant, but not in female group. 5. When the illness had lasted 6-10 years, scales of F & Sc were significantly higher (p<. 05) than the patients under 5 years of illness. When the illness lasted over 11 years, Hy scale was significantly higher (p<. 05) than the patients under 5 years of illiness. When the illiness lasted over 11 year, Hy scale was significantly higher(p<. 05) than the patients with 6-10 years of the illiness. 6. In adolescent group, D scale was significantly higher(p<. 05) than in control group. In early adulthood group, scales of Hs, D, Hy, Pt, Sc and Ma (p<. 01) as well as scales of F, Pa, & Si (p<. 05) were significantly higher than in control group. In middle adulthood group, scales of Hs, D, Hy & sC (P. 01) as well as scales of F & Pt (p<. 05) were significantly higher than in control group.

불임여성에서 스트레스 지각, 대처방식, 우울 및 불안

조행신,정상근,류철희,황익근 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.3

목 적 : 불임여성에서 불임에 의한 스트레스 때문에 심리적 후유증이 발생할 수 있다. 이러한 심리적 영향을 평가하여 정신과적 중재의 필요성을 파악하고자 하였다. 방 법 : 환자군은 전북대학병원 산부인과 불임클리닉에 내원한 불임으로 확직된 34명을 대상으로 하였다. 대조군은 환자군과 연령 및 학력수준이 대등한 1명 이상의 자녀를 둔 34명의 건강한 기혼여성으로 선정하였다. 양군모두 인구통계학적 특성 및 불임관련사항에 관한 반구조화된 설문지, 스트레스 지각검사, 대처방식 체크 리스트, Beck Depression Inventory, Hamilton Anxiety Scale, Hamilton Rating Scale for Depression, SCL-90-R 그리고 상태-특성불안 검사를 이용하여 평가하였다. 결 과 : 불임여성은 대조군에 비해 다음과 같은 결과를 보였다. 1) 스트레스 지각검사 중 금전적인 문제에 스트레스를 더 많이 지각하고 있었으며 (p=0.026), 최근 1년간의 부정적 사건 및 중성적 사건의 빈도가 유의하게 더 높았다.(p〈0.05). 2) 스트레스 대처방식중 정서완화적 대처가 주가되는 소극적 대처의 빈도가 유의하게 높았다(p〈0.05). 3) Hamilton 우울척도수준, Hamilton 불안척도수준 그리고 특성불안수준이 유의하게 더 높았다(p〈0.05). 4) Beck 우울수준, SCL-90-R의 우울수준 그리고 상태-특성 불안수준이 높을수록 일주일간의 스트레스 지각점수가 더 높았으며(p〈0.05), Beck 우울수준, Hamilton 불안수준 그리고 상태-특성 불안 수준이 높을수록 소극적 대처의 빈도가 더 높았다(p〈0.05). 결 론 : 상기 결과로 미루어 불임여성들이 소극적 대처방식과 높은 수준의 우울, 불안을 보이는 바, 이에 대한 정신과적 중재가 필요할 것으로 생각한다. Objective : The purpose of this study was to investigate psychological impacts of infertility related stress in Korean infertile women. Methods : Both the 34 infertile women group and the control group(34 married women) were evaluated by using Semistructured Questionnaire, Stress Perception Scale, Coping Behavior checklist, Beck Depression Inventory(BDI), Hamilton Anxiety Scale(HAS), Hamilton Rating Scale for Depression(HRSD), SCL-90-R and State Trait Anxiety Inventory(STAT). Results : Perceived financial stress of negative and neutral life events and frequency of passive coping(especially, emotion-focused coping) were significantly higher in infertile women than control group. In infertile women, totally perceived stress was positively correlated with BDI, SCL-90-R(depression) and STAI. Passive coping behavior was positively correlated with EDI, HAS and STAI. Conclusion : Above results suggest that infertile women would have a tendency to passive coping and high level of depression and anxiety, and should be considered for psychiatric intervention.