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        목표물질 스크리닝을 위한 피이크 인식 알고리즘

        민홍기,홍승홍,Min, Hong-Kee,Hong, Seung-Hong 대한의용생체공학회 1993 의공학회지 Vol.14 No.2

        In this paper, the peak detection algorithm was developed for the purpose of screening of the target compounds. Algorithm is divided into searching the characteristic ion and peak detection. The heuristic knowledge about analytical chemistry was applied for the searching the characteristic ion. Peak detection was accomplished in comparison with the peak identification strings and pattern strings around the retention time. Pattern strings are composed with the number which generated by pattern identification function. The variables of pattern identification function are the codes which represent the difference of two adjacent abundances Some of the free steroids were selected to demonstrate the proposed algorithm.

      • KCI등재

        하이브리드 셋업을 이용한 에너지 효율적 센서 네트워크 클러스터링

        민홍기,Min, Hong-Ki 한국융합신호처리학회 2011 융합신호처리학회 논문지 (JISPS) Vol.12 No.1

        센서 네트워크에서 사용되는 동적 클러스터링 방식은 주기적으로 클러스터 구조가 바뀌는 셋업과정으로 인한 에너지 소모가 크다. 셋업과정은 보안적용을 해야 할 경우 보안 키가 주기적으로 재 생성되는 등 클러스터 구성 이외에 추가적인 에너지 낭비가 발생한다. 본 논문은 최초에 구성된 클러스터 알고리즘과 이후 반복적으로 발생되는 클러스터 재셋업 알고리즘을 달리하는 하이브리드 방식을 제안한다. 재 셋업에서는 고정된 클러스터 내에서 순환적으로 클러스터 헤드노드를 선출하는 순환적 클러스터 헤드선정(RRCH: Round-Robin Cluster Header)방식을 이용하여 에너지 소모를 줄인다. 보안키 생성 및 적용으로 추가되는 에너지 소모는 클러스터가 지속적으로 고정되기 때문에 최초 클러스터 형성 때 사전 배포하는 방식으로 해결된다. 본 논문에서 제안한 방식의 타당성을 확인하기 위해 모의실험을 실시하였다. 라운드 구간을 100번 반복하여 클러스터 구성과 데이터 전송을 포함한 전체 에너지 소모량을 측정하였다. 결과는 제안한 방식이 LEACH방식보다 평균 26.5%, HEED방식보다 평균 20% 적게 소모되는 것을 확인하였다. Cluster-based routing is high energy consumption of cluster head nodes. A recent approach to resolving the problem is the dynamic cluster technique that periodically re-selects cluster head nodes to distribute energy consumption of the sensor nodes. However, the dynamic clustering technique has a problem that repetitive construction of clustering consumes the more energies. This paper proposes a solution to the problems described above from the energy efficiency perspective. The round-robin cluster header(RRCH) technique, which fixes the initially structured cluster and sequentially selects cluster head nodes, is suggested for solving the energy consumption problem regarding repetitive cluster construction. A simulation result were compared with the performances of two of the most widely used conventional techniques, the LEACH(Low Energy Adaptive Clustering Hierarchy) and HEED(Hybrid, Energy Efficient, Distributed Clustering) algorithms, based on energy consumption, remaining energy for each node and uniform distribution. The evaluation confirmed that in terms of energy consumption, the technique proposed in this paper was 26.5% and 20% more efficient than LEACH and HEED, respectively.

      • 肉芽腫內 犬蛔蟲 幼蟲의 感染性에 關한 硏究

        閔弘基 梨花女子大學校 醫科大學 醫科學硏究所 1981 EMJ (Ewha medical journal) Vol.4 No.3

        The objective of this paper is to test the reinfectivity of Toxocara canis larvae in mice that are fed with rat's liver tissue containing larvae in granuloma formed by administration of infective eggs of dog ascarid. A serial experiment was carried out with 10 non-pregnant mice to observe the pattern of granuloma formation and with 10 pregnant mice to establish the intrauterine and the intramammary migrations. Digestion method using Baermann apparatus and histological examination of the tissues of the tissues were applied as required. The results are summarized as follows: 1) Typical granulomas were formed in the liver of white rats. 2) In mice fed with liver tissue of white rats, granulomas were formed more or less rapidly and necrotic change was observed in the center of the granuloma. 3) Some larvae were recovered from the uterus and placenta at the 15th day of pregnancy, but not in the fetus. 4) A few larvae were deteced in mammary gland at the first day after parturition. However, larva disappeared from the unterus after parturition.

      • 개蛔蟲 幼蟲의 마우스 腦組織內 移行 分布樣相

        閔弘基 梨花女子大學校 醫科大學 醫科學硏究所 1982 EMJ (Ewha medical journal) Vol.5 No.4

        The present study was undertaken to get further information on the migratory gehavior of Toxocara canis larvae in the central nervous system in eperimentally infected mice. Mice were infected with approximately 500 of infective eggs of T.canins. Accor-ding to the schedule, mice, 5 males and 5 females, were sacrificed at 2,3,5,7,14,21,28 and 56 days after injection and the brain tissue was extracted from each mouse and devided into six parts ; cerebrum, cerebellum, medulla oblongata, olfactory bulb, potuitary and spinal cord. Number of the larvae was counted qu0alitatively and quantitatively. The results are summarized as follows : 1. Total recovery rate(in average) of the larvae in the brain at the various in-tervals gradually inceased from 0.4% to 10.6% with the highest rate on the 28th day of post-infection. 2. Total recoery rates(in average) of the larvae obtained throughout the study were 54.2% in male and 45.8% in female, out of 504 larvae. 3. Distribution rates of the larvae were revealed as high as 57.5% in cerebrum and 32.5% in cerebellum, and 4.4% in medulla oblongata, 2.8% in spinal cord, 2.0% in olfactory bulb and 1.6% in pituitary in decreasing order. 4. Number of the larvae per mg of wet weight of the brain found was 0.06 in cerebrum and cerebellum, 0.03 in olfactory bulb and pituitary, 0.02 in medulla oblongata and 0.01 in spinal cord, respectively.

      • 江華郡內 肺吸蟲症 濃厚蔓延地域에 있어서의 疫學的 樣相의 變化

        閔弘基,田桂植 梨花女子大學校 醫科大學 醫科學硏究所 1987 EMJ (Ewha medical journal) Vol.10 No.4

        In Korea, paragonimiasis is one of the most important endemic parasitic diseases with significant clinical relvance. Since 1917 when Kobayashi has reported a high infection rate(88.0%) of paragonimus metacercariae among crayfish, an important intermediate host, Kanghwa-gun has been known to be a hyperendemic region of paragonimiasis. The present authors carried out an epidemiologic studies to obtain some current informations on the change in epidemiologic aspects of paragonimiasis in Giljeong-ri, Yangdo-myun, Kanghwa-gun, the most hyperendemic region. The infection status of Paragonimus metacercariae in crayfish have been examined. And a total of 392 students of Kangnam Middle School was examined by the intradermal test with Paragonimus antigen. In order to detect Paragonumus egg from the positive reactors, the fecal and sputum examinations were performed. As shown in Tables 1 and 2, there are marked reducing tendencies in the infection rate in crayfish and in the average number of metacercariae per crayfixh examined; 66.2% and 17.2 in 1981, 59.6% and 8.4 in 1984 and 20.0% and 0.6% in 1987, respectively. According to Table 3, 7.1% of the students showed positive reaction to Paragonimus autigeu with the sexual distribution of 8.0% in male and 6.0% in female. However, no Paragonimus eggs were found from the positive reactors by the fecal and sputum examinations.

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