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      • KCI등재후보

        관성/확산필터를 이용한 나노입자의 분류기술 연구

        김용구,이상열,김한나,노학재,봉춘근,김대성,Kim, Yonggu,Lee, Sangyul,Kim, Hannah,Noh, Hakjae,Bong, Choonkeun,Kim, Daesung 한국입자에어로졸학회 2015 Particle and Aerosol Research Vol.11 No.2

        The purpose of this research is to find out the collection property of nanoparticle in diffusion filter to know particle size dispersion of nanomaterial using inertial force and principle of Brownian diffusion motion. We used inertial filters which are two different type and diffusion filters made by various kinds of Wiremesh and the different pieces of filter to compare with particle size distribution using NaCl particles. Finally, We made a conclusion as follows : (1) the bigger available charging volume is and the larger specific surface area of inertial filter is, the better collection efficiency is. (2) The higher wire-mesh number of filter is, the more collection efficiency of small particle is increasing because the wire of the higher Wiremesh number filter is thinner and denser. (3) The more pieces of wire-mesh filter, the more collection efficiency is increasing because it makes the residence time longer.

      • SCOPUSKCI등재

        A Statistical Thermodynamic Study on the Conformational Transition of Oligopeptide Multimer

        김용구,박형석,Kim, Yong Gu,Park, Hyeong Seok Korean Chemical Society 1996 Bulletin of the Korean Chemical Society Vol.17 No.2

        The conformational transition of oligopeptide multimer,-(HPPHPPP)n-, is studied (H:hydrophobic amino acid, P:hydrophilic amino acid). The helix/coil transitions are detected in the multimer. The transition depends on the number of amino acid in the sequence, the concentration of the oligopeptide, and temperature which affects helix stability constant (${\xi}$) and hydrophobic interaction parameter (wj). In the thermodynamic equilibrium system jA${\rightarrow}$Aj (where A stands for oligopeptide monomer), Skolnick et al., explained helix/coil transition of dimer by the matrix method using Zimm-Bragg parameters ${\xi}$ and $\sigma$ (helix initiation constant). But the matrix method do not fully explain dangling H-bond effects which are important in oligopeptide systems. In this study we propose a general theory of conformational transitions of oligopeptides in which dimer, trimer, or higher multimer coexists. The partition of trimer is derived by using zipper model which account for dangling H-bond effects. The transitions of multimers which have cross-linked S-S bonds or long chains do not occur, because they keep always helical structures. The transitions due to the concentration of the oligopeptides are steeper than those due to the chain length or temperature.

      • KCI등재

        정신분열증 환자에서 혈장 HVA 및 5-HIAA 농도와 정신병리와의 상관성

        김용구,박성근,김인,이민수,Kim, Yong-Ku,Park, Sung-Geun,Kim, Leen,Lee, Min-Soo 대한생물정신의학회 1997 생물정신의학 Vol.4 No.1

        The recent hypothesis about the pathophysiology of schizophrenia has been centered mainly on two theories, i.e. dopamine hypothesis and serotonin hypothesis. We investigate the correlations between plasma monoamine metabolite concentrations and clinical symptoms in schizophrenic patients. The first purpose of our study was to examine whether the plasma levels of HVA(homovanillic acid) and 5-HIAA(hydroxyindoleacetic acid) are significantly different in schizophrenics, compared to normal controls. And, with the intention of clarifying the interaction between dopaminergic system and serotoninergic system, the ratio of HVA/5-HIAA also was measured. The second purpose was whether the basal(pre-treatment) levels of these metabolites show the correlation with clinical symptoms. Finally, third purpose was whether basal HVA and 5-HIAA levels can be held as a predictor of treatment response. We used Scale for the Assessment of Positive Symptoms(SAPS) and Scale for the Assessment of Negative Symptoms(SANS) as the clinical symptom rating scales. Our results were as followed, 1) only the level of basal plasma HVA was significantly differ in schizophrenics. 5-HIAA and HVA/5-HIAA were not. 2) basal HVA showed significant correlation with SAPS score, especially delusion subscale. 3) the higher was the basal HVA level, the more improvement in clinical symptoms was observed. The basal 5-HIAA level and the HVA/5-HIAA ratio did not show any significant findings. These results support the dopamine hypothesis of schizophrenia, but fail to examine on the possible involvement of serotonin in schizophrenia.

      • KCI등재

        번역의 국제정치학 : 마틴과 휘튼

        김용구 한림대학교 한림과학원 2008 개념과 소통 Vol.1 No.1

        이질 문명권 사이의 번역에는 오해,굴절,선택이 동반된다. 이런 현상에 관해서는 여러 원론적인 견해나 초보적인 이론 구성을 위한 노력들이 있다. 그러나 그런 현상을 번역의 역사적 현장에서 분석한 업적은 그리 흔하지 않다. 이 논문은 1864년 마틴(W.A.P. Martin)이 휘튼{H. Wheaton)의 국제법 저서를 한역하면서 나타난 위의 현상들을 분석한 글이다. 이 과정에서 휘튼의 저서를 사대질서의 회전(會典)으로 오해 했다. 이것은 유럽 국제사회와 사대질서를 혼동한 결과이다. 휘튼의 저서는 실증법적인 연구인데,마틴이 자연법적인 색채를 가미해 굴절하여 번역했다. 자연법적인 전통을 지닌 조선과 중국의 지식인들에게 크게 영항을 미치게 된 원인이다. 휘튼의 저서는 유럽 공법의 지식이 없던 동양의 지식인에게는 난해했기 때문에 선택이 뒤따르게 되었다. 결과적으로 독립,균세, 자주와 같이 필요한 개념만을 수용하게 되었다. 이처럼 오해,굴절,선택을 동반한 번역으로는 유럽 국제정치의 본질을 파악할 수는 없다. 오늘날 한국의 국제정치학은 기본적으로 이런 번역의 국제정치학 수준에 머물고 있다. As a specific case of communication across heterogeneous civilizations, translation entails unique cultural phenomena, characterized as misunderstanding, distortion, and selection. While various perspectives and studies have attempted to theorize such phenomena, they have remained largely at an abstract level. We need to move beyond general discussions, so that, by placing the issue in the context of concrete history, and employing textual analysis, we may trace the processes and the consequences of translation. Focusing on W.A.P. Martin's 1864 Chinese translation of H. Wheaton's Elements of International Law, this paper, therefore, analyzes the phenomena of misunderstanding, distortion, and selection that originated in cross-civilization translation. Wheaton's work was written from a thoroughly positivistic viewpoint, the dominant paradigm of international law in Europe, at the time. In the absence of any knowledge of European public law, however, it was difficult for Choso˘n intellectuals, or for their Chinese counterparts, to understand various key concepts of international law that Wheaton presented. Knowing this when he translated Wheaton's work into Chinese, Martin altered the nature of the original text by adding natural law elements, which were familiar to Choso˘n and Chinese intellectuals. As such, this translated Chinese version greatly influenced East Asian intellectuals, who were deeply entrenched in the natural law tradition. Yet, this sort of distortion in translation resulted in misunderstanding and selection, Viewing their subject-matter through the distorted lens of translation, Choso˘n and Chinese intellectuals failed to identify the essential differences between European public law and Sadae order, as shown by the fact that they treated Wheaton's work as if it were the statute of Sadae order. Moreover, due to the ensuing selection of ideas, Choso˘n and Chinese intellectuals accepted only the concepts they needed, such as independence, balance of power, and autonomy, a reaction which sheds light on one important lesson: that translation accompanied by the phenomena of misunderstanding, distortion, and selection inhibited a proper appreciation of the fundamental nature of Euro-centric international politics.

      • KCI등재

        Bayesian estimation in the generalized half logistic distribution under progressively type-II censoring

        김용구,강석복,서정인 한국데이터정보과학회 2011 한국데이터정보과학회지 Vol.22 No.5

        The half logistic distribution has been used intensively in reliability and survival analysis especially when the data is censored. In this paper, we provide Bayesian estimation of the shape parameter and reliability function in the generalized half logistic distribution based on progressively Type-II censored data under various loss functions. We here consider conjugate prior and noninformative prior and corresponding posterior distributions are obtained. As an illustration, we examine the validity of our estimation using real data and simulated data.

      • KCI등재

        Bayesian estimations on the exponentiated half triangle distribution under Type-I hybrid censoring

        김용구,강석복,서정인 한국데이터정보과학회 2011 한국데이터정보과학회지 Vol.22 No.3

        The exponenetiated distribution has been used in reliability and survival analysis especially when the data is censored. In this paper, we derive Bayesian estimation of shape parameter and reliability function in the exponenetiated half triangle distribution based on Type-I hybrid censored data. Here we consider conjugate prior and nonin-formative prior and obtained corresponding posterior distributions. As an illustration, the mean square errors of the estimates are computed. Comparisons are made between these estimators using Monte Carlo simulation study.

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