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      • SCIEKCI등재

        대두 Bowman - Birk 형 Protease Inhibitor 들의 품종간 비교

        김수일,이홍석,노범섭 한국농화학회 1989 Applied Biological Chemistry (Appl Biol Chem) Vol.32 No.2

        Bowman-Birk type protease inhibitors of soybeans were purified with gel filtration on Sephadex G-75. Significant differences were found in the content and in the electrophoretic patterns of the purified protease inhibitors. Ten among fourteen electrophoretic bands appeared as protease inhibitors. The chymotrypsin and trypsin inhibiting activities in soybeans showed three and four fold variation respectively. And the cultivars with higher chymotrypsin inhibiting activities seemed to have higher cysteine contents.

      • KCI우수등재

        FWD에 의한 4층 아스팔트 포장 구조체의 층별 탄성계수 추정

        김수일,유지형,Kim, Soo Il,Yoo, Ji Hyeung 대한토목학회 1990 대한토목학회논문집 Vol.10 No.2

        본 연구에서는 합리적이고 과학적인 포장 구조체의 유지 관리를 위하여 포장체의 구조적 상태를 평가하는데 중요하게 사용되는 포장체 각 층의 탄성계수 추정 방법에 대하여 연구하였다. 차량하중에 의한 포장체의 구조적 거동을 측정하는 비파괴시험 방법으로 Falling Weight Deflectometer(FWD)를 택하였으며, 측정 결과를 합리적으로 해석하기 위하여 다층탄성이론에 근거한 해석 프로그램을 사용하였다. 국내에서 널리 사용되고 있는 고속도로 단면 모델에 요인배치법(factorial design)을 적용하여 쇄석과 안정처리기층을 갖는 경우 각각에 대한 이론적 처짐특성을 분석하고, 이로부터 각 경우의 층별 탄성계수 추정식을 제안하였다. 처짐 변화율에 따른 탄성계수 변화율에 과한 상관식을 4층 구조체 층별로 개발함으로써 FWD시험의 처짐으로부터 포장체 각 층의 탄성계수를 추정할 수 있는 보다 효율적이며 정도가 높은 역산방법을 제안하고 이를 전산화하였다. 또한 4층 아스팔트 포장체의 실제 가능한 수치 모델에 대한 검증을 통하여 본 연구에서 제안한 역산 방법의 신뢰성 및 타당성을 입증하였다. An inverse self-iterative procedure is developed to determine layer moduli which are significant for the structural evaluation of pavements in developing rational and analytical rehabilitation technique. Falling weight deflectometer(FWD) is adopted as a non-destructive testing(NDT)device. The layer elastic theory is used to interpret NDT data. The theoretical deflection basins of pavement structures obtained by full factorial design are used for a parametric study on the characteristics of deflection basins and regression analyses. Regression equations to estimate layer moduli of flexible pavements are proposed through the regression analyses of theoretical deflection basins. The relationships between the rate of change of moduli and deflections are developed for the efficient iteration. An inverse self-iterative procedure to ensure the accuracy of the layer moduli is proposed. Validity and applicability of the developed procedure are verified through various numerical model tests.

      • KCI우수등재

        가상암반층의 깊이를 고려한 아스팔트 포장체의 층별 탄성계수 추정기법의 개발

        김수일,이광호,Kim, Soo Il,Lee, Kwang Ho 대한토목학회 1993 대한토목학회논문집 Vol.13 No.4

        본 연구에서는 비파괴 시험장비인 FWD를 사용하여 아스팔트 콘크리트 포장체 각 층의 탄성계수를 추정할 때 고려하여야 하는 가상암반층의 깊이를 FWD의 충격지속시간과 충격하중에 의한 포장체내의 압축과 속도로부터 산정할 수 있는 알고리즘을 제시하였다. 또한 FWD 시험자료를 입력치로하여 포장체 각 층의 탄성계수를 추정하는 전산 프로그램인 MFPD에 본연구에서 제시한 알고리즘을 적용 보완하였다. 보완된 MFPD의 탄성계수 추정결과에 대한 타당성을 살피기 위하여 FWD를 제작하여 현장시험을 실시하였으며 아울러 검증시험을 병행 실시하였다. 검증시험으로는 FWD 시험위치에서의 평판재하시험, 채취시료의 실내시험(마샬안정도시험, 압축시험), 표면파시험을 실시하였다. 이들 시험성과를 비교분석한 결과 가상암반층을 고려할 수 있도록 보완한 MFPD의 역산결과가 충분히 신뢰성 있음을 알 수 있었다. The computer program, MFPD, which is used to backcalculate the layer moduli of asphalt concrete pavement system is modified by contemplating the depth to virtual bedrock in this study. An algorithm to estimate the depth to virtual bedrock is developed through the analysis of FWD impulse load duration and the compression wave velocity of ground. For verification of the modified MFPD, FWD is fabricated and then FWD field tests and verification tests are carried out at the test sites. Plate loading tests and surface wave propagation tests are performed at FWD test sites. Laboratory tests (Marshall stability tests, unconfined compression tests) for sampled asphalt concrete specimens are also carried out. From comparison analysis, the validity and applicability of the modified MFPD are verified.

      • KCI등재후보

        Cultural Component in the Content of Korean Studies and Language Education in Kazakhstan

        김수일,라리오노바 한국글로벌문화학회 2018 글로벌문화연구 Vol.9 No.4

        The study relevance both by the needs of methodical science in theoretical development of socio-cultural component in teaching a foreign language in general, and the needs of Kazakhstan higher education institutions for textbooks with a focus on "dialogue of cultures", providing for interconnected communicative and socio-cultural development of future professionals. The paper assesses the content of national-cultural component structure in teaching the Korean language to Kazakhstan University students. This study is determined both by the needs of methodical science in theoretical development of socio-cultural component of teaching a foreign language in general, and Kazakhstan higher education institutions’ needs for textbooks with a focus on "dialogue of cultures", providing for interconnected communicative and socio-cultural development of future professionals. The need to address the problem of the socio-cultural and national-cultural component in the content is caused by the new goal of teaching the Korean language, understood as developing students' ability of intercultural communication. The problem of creating an image of Korea, as a native Korean speaker’s country, as well as that of Kazakhstan, has a political sound, since its solution is connected with overcoming a possible barrier between the two peoples, the destruction of obstacles between Korean and Kazakhstan linguistic cultures. Intensification of an adult communicator’s social connections, expansion of his field of activity as a subject of the “cultural dialogue” makes the processes of communication increasingly diverse and intense. This requires improving the structure of a future Korean teacher’s thesaurus (model of consciousness) at all levels of his professional communicative activities.

      • Retinoic acid가 배양중인 백서 구개 내측연상피세포에 미치는 영향

        김수일,이영호,김원식 충남대학교 의과대학 지역사회의학연구소 1995 충남의대잡지 Vol.22 No.1

        For the study on the effect of retinoic acid on the medial edge epithelial cells of fetal rat palate in vitro, the GD 15 fetal palatal shelves of Sprague-Dawley rats were cultured. Excised palatal shelves were placed on the milipore filter, and cultured in organ culture dish(Falcon 3037). Retinoic acid was dissolved in 0.1% DMSO and used at concentration of 10^-5M. The media were changed every 24hrs, and the palatal shelves were harvested after 24, 48, 72 hrs after culture. The palatal MEE cells were observed with LM & TEM. The results were as follows ; 1. The palatogenesis of rat in vitro was delayed more or less compared with in vivo. 2. In LM photographs, the palatogenesis was delayed in the retinoic acid-treated group significantly. 3. In TEM photographs, the number of hemidesmosomes and desmosomes were increased in the retinoic acid-treated group. The basal lamina in the retinoic acid-treated group was intact, but not in control group. Cytoplasmic condensations, nuclear fragmentations, and apoptotic bodies were found in the control group. According to the above results, it is considered that retinoic acid inhibits programmed cell death and enhances proliferation of cells of the medial edge epithelium of rat palate. However, the exact action mechanism of retinoic acid on programmed cell death of MEE cells are still unclear.

      • KCI등재

        Management of Laryngopharyngeal Reflux in Asia

        김수일,Jerome R. Lechien,Tareck Ayad,Huan Jia,Seyyedeh Maryam Khoddami,Necati Enver,Sampath Kumar Raghunandhan,Abdul Latif Hamdan,은영규 대한이비인후과학회 2020 Clinical and Experimental Otorhinolaryngology Vol.13 No.3

        Objectives. This study was conducted to investigate the current practices of Asian otolaryngologists for laryngopharyngeal reflux (LPR). Methods. An online survey about LPR was sent to 2,000 members of Asian otolaryngological societies, and a subgroup analysis was performed between Western and Eastern Asian otolaryngologists. The survey was conducted by the Laryngopharyngeal Reflux Study Group of Young Otolaryngologists of the International Federation of Oto-rhino-laryngological Societies. Results. Among approximately 1,600 Asian otolaryngologists, 146 completed the survey (62 from Western Asian countries, 84 from Eastern Asian countries). A substantial majority (73.3%) of the otolaryngologists considered LPR and gastroesophageal reflux disease to be different diseases. The symptoms thought to be closely related to LPR were coughing after lying down, throat clearing, and globus sensation. The findings thought to be closely related to LPR were posterior commissure granulations and hypertrophy, arytenoids, and laryngeal erythema. The respondents indicated that they mostly diagnosed LPR (70%) after an empirical therapeutic trial of proton pump inhibitors (PPIs). Although multichannel intraluminal impedance-pH (MII-pH) monitoring is a useful tool for diagnosing nonacid or mixed LPR, 78% of Asian otolaryngologists never or very rarely used MII-pH. Eastern Asian otolaryngologists more frequently used once-daily PPIs (64.3% vs. 45.2%, P=0.021), whereas Western Asian otolaryngologists preferred to use twice-daily PPIs (58.1% vs. 39.3%, P=0.025). The poor dietary habits of patients were considered to be the main reason for therapeutic failure by Asian otolaryngologists (53.8%). Only 48.6% of Asian otolaryngologists considered themselves to be adequately knowledgeable and skilled regarding LPR. Conclusion. Significant differences exist between Western and Eastern Asian otolaryngologists in the diagnosis and treatment of LPR. Future consensus statements are needed to establish diagnostic criteria and therapeutic regimens.

      • KCI등재

        과호흡부활법이 간질환자의 뇌파학적 진단에 미치는 영향

        김수일 大韓神經精神醫學會 1980 신경정신의학 Vol.19 No.3

        In this study, it was attempted to reveal the characteristic effects of hyperventilation on EEG in epileptic s. Two hundred and forty-one idiopathic epileptics who had visited our neuro-psychiatric department from June 1975 to December 1979 at the Seoul Red Cross Hospital were included in this study. The results of this study were as follows. 1. Among the 241 idiopathic epileptics, 57.3%(138) showed abnoraal EEG findings in routine EEG examination. 2. During hyperventilation and routine EEG examination in 241 cases of the idiopathic epileptics, 69.3%(167) showed abnormal EEG findings. It was revealed that there was an increase of abnorml EEG findings during EEG with hyperventilation from 57.3% to 69.3%. 3. In age distribution, diagnostically meaningful abnormal EEG findings were observed in 60% of the cases in the age group of 5-19 years, 23% of the cases in the age group of 20-39 years, and none of the age group of more than 50 years old. 4. In clinical type distriburion, it was revealed that 35.7% of Petit mal seizure, 18.4% of other focal sejzure, 11.1% of Jacksonian seizure, 10.1% of Grand mal seizure, 9.7% of Psychomotor seizure, and 4.5% of Adversive seizure, showed abnormal EEG findings in EEG with hyperventilation technique. From this results, it was concluded that hyperventilation technique was most significantly useful in EEG diagnosis of Petit mal epilepsy and of less significance in other type of seizure. 5. In sex distribution, 9.5% of male Patients and 16.0% of female Patients showed abnormal EEG findings in EEG with hyperventilation technique. From this results, it was concluded that hyperventilation technique was more significantly useful for EEG diagnosis of female epileptics.

      • 쑥가루와 밀가루 복합분의 이화학적 특성

        김수일 東國專門大學 1994 金龜論叢 Vol.2 No.1

        쑥을 유용식물자원으로 활용하기 위하여 밀가루와 쑥가루복합분을 amylograph와 farinograph를 이용하여 이화학적 특성을 조사한 결과는 다음과 같다. 1. 일반성분은 밀가루보다 쑥가루가 조단백질의 경우 1.8배, 조지방의 경우 4배 정도 함량이 높았다. 2. Amylogram 특성에서 호화온도는 복합분이 약간 높았으나 유의적인 차이는 없었고 최고점도는 쑥가루 5% 첨가한 경우가 가장 높았으며 복합분의 색도는 첨가비율이 높을수록 밝기가 떨어졌다. 3. Farinogram 특성에서는 수분흡수율이 밀가루에 비해 쑥가루 첨가비율이 증가할수록 3∼14%증가하였으며 반죽의 안정도도 증가하였으나 쑥가루 5% 첨가의 경우가 가장 높았다.

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