난독증을 주소로 내원한 한국인 환자들의 임상양상: 얼렌증후군과의 연관성

김승현,조윤애,Seung-Hyun Kim,Yoonae A Cho 대한안과학회 2010 대한안과학회지 Vol.51 No.12

Purpose: To evaluate the main symptoms and associated ocular diseases in patients with dyslexia (reading difficulty) in Korean subjects. Methods: A total of 16 patients were enrolled in the present study. Eleven of the patients with Meares-Irlen syndrome whose symptoms improved with tinted lenses comprised Group 1. The other 5 patients whose reading difficulty improved with other ocular therapy and did not require tinted lenses comprised Group 2. The main symptoms causing dyslexia and associated ocular diseases were evaluated. Results: The mean age was 18.9 ± 8.9 years in Group 1, and 20.4 ± 12.3 years in Group 2. In Group 1, the most common symptoms while reading were doubling (72%), difficulty to move lines (46%), letter reversal (27%) and blurring or ocular pain (27%). On the other hand, blurring (100%) with fatigue or pain (20%) was documented in Group 2. The associated ocular diseases in Group 1 and Group 2 were refractive error (63% and 20%), dry eye (18% and 60%), and exophoria (18% and 60%), respectively. Conclusions: Doubling and difficulty to move lines while reading were the main specific symptoms in Meares-Irlen syndrome in the present study. Refractive error, dry eye, and exophoria were commonly associated in patients with dyslexia. J Korean Ophthalmol Soc 2010;51(12):1639-1642

정신분열증환자에서 Haloperidol 투여에 따른 임상효과와 혈장 Homovanillic Acid의 농도 및 혈장 5-Hydroxyindoleacetic Acid 농도와의 관계

김승현,이민수,곽동일,Kim, Seung Hyun,Lee, Min Soo,Kwak, Dong Il 대한생물정신의학회 1995 생물정신의학 Vol.2 No.1

The Purposes of this study were to examine plasma homovanillic acid(pHVA) levels and 5-hydroxyindoleacetic acid(pHIAA) levels in schizophrenics during haloperidol treatment, and to assess the association of pHVA and pHIM levels with their psychopathology and treatment responses. Fourteen patients entered the study and pHVA, pHIAA levels were measured at baseline, first week, second week and fourth week during treatment. Also, plasma haloperidol levels were measured at first week, second week and fourth week. Psychopathology was evaluated with Brief Psychiatric Rating Scale(BPRS) at baseline, 1st week, 2nd week and 4th week. 1) There were significant differences on the duration of illness and total BPRS scores at baseline between higher pHVA group(baseline pHVA level >7.72ng/mL) and lower pHVA group(baseline pHVA level <7.72ng/mL). 2) There was no significant difference on the duration of illness between higher pHIM group(baseline pHIAA level >3.18ng/mL). and lower pHIAA group(baseline pHIAA level <3.18ng/mL). 3) The Means of pHVA levels at 1 st week and 2nd week after treatment decreased significantly in the higher pHVA group and did not change in the lower pHVA group. 4) In the higher pHIAA group, the mean of pHIAA levels at 4th week after treatment decreased significantly, but did not change in the lower pHIAA group. 5) Between the higher pHIVA group and lower pHVA group, the response rates(percentile improvement) after treatment were not different from each other, but there was significant difference on the response rate between the lower pHIAA group and higher pHIM group at 2nd week. 6) There was significant correlation between total BPRS scores and pHVA levels in the higher pHVA group during treatment. The results suggest that repeated measurement of pHVA levels and pHIAA levels following antipsychotic treatment have prognostic significance for response. Also, shcizophrenics whose have relatively nigh levels of pHVA, or relatively low levels of pHIAA before treatment will show a favorable early responses to antipsychotics.

도시생태계 건전성 증진을 위한 녹지총량 평가법 개발과 적용

김승현,공학양,김태규,Kim, Seung-Hyun,Kong, Hak-Yang,Kim, Tae-Kyu 응용생태공학회 2015 Ecology and resilient infrastructure Vol.2 No.4

본 연구는 도시생태계 건전성 증진을 위한 녹지총량제 도입을 위해 국내 법규를 토대로 녹지총량의 정의와 유형을 분류하고, 전국단위의 녹지총량 평가지표를 도출하여 산정하였으며, 이를 토대로 전국 시도별 녹지총량을 지수화 하였다. 결과는 다음과 같다. 첫째, 녹지총량은 "도시공원 및 녹지 등에 관한 법률", "토의 계획 및 이용에 관한 법률" 등에서 정의하는 '녹지', '공원녹지', '녹지지역' 등을 포함하는 포괄적 의미의 녹지이다. 둘째, 녹지총량 산정을 위한 녹지의 유형은 도시공원과 완충녹지, 경관녹지, 연결녹지 등의 시설녹지를 포함하는 공원녹지, 보전녹지지역, 생산녹지지역, 자연녹지지역을 포함하는 녹지지역, 교목, 관목, 지피 등의 식생으로 점유된 산림, 초지, 습지를 포함하는 녹피지로 분류할 수 있다. 셋째, 1인당 공원녹지, 공원녹지율, 1인당 녹지지역, 녹지지역율, 1인당 녹피면적, 녹피율 등 6가지 평가지표를 적용하여 전국 시도별 녹지총량을 산정하였으며, 이를 토대로 시도별 녹지총량을 지수화한 결과에 따르면 특별 광역시에서는 세종특별시가 가장 높았고 서울특별시와 대구광역시가 가장 낮았으며, 도 지역에서는 충청북도가 가장 높았고 경기도와 제주특별자치도가 가장 낮았다. This study defined and classified no-net-loss-of-greenness (NNLG) based on the law, and then assessed the NNLG index by metropolitan cities and provinces in Korea after estimating NNLG evaluation indicators for the introduction of NNLG for health improvement of urban ecosystems. The results are as follows. First, NNLG was the comprehensive meaning that was included in the greenbelt and park greenbelt and the green area which was defined by the Act on Urban Parks, Greenbelts, etc. and the National Land Planning and Utilization Act respectively. Second, NNLG was classified as a park greenbelt which was included urban parks and greenbelts such as buffer greenbelts, scenic greenbelts, and connecting greenbelts, green areas which was included in green conservation areas, green production areas, green natural areas, and green coverage which is included forests, grasslands, and wetlands that were occupied by vegetation such as trees, shrubs, and plants. Third, NNLG index by cities and provinces was assessed based on the estimation of NNLG evaluation indicators, which included parks and greenbelt areas per capita, green areas per capita, green coverage per capita, ratio of parks and greenbelts, ratio of green areas, and ratio of green coverage. As a result, Sejong city got the highest point of NNLG index and Seoul and Daegu got lowest points of NNLG index among metropolitan cities in Korea. Chungbuk got the highest point of NNLG index and Kyonggi and Jeju got lowest points of NNLG index among provinces in Korea.

블록체인 기반 접근제어 기술 동향

김승현,김수형,Kim, Seung-Hyun,Kim, Soohyung 한국전자통신연구원 2019 전자통신동향분석 Vol.34 No.4

As companies use increasing amounts of data more and more, people are more concerned about protecting their privacy. Many researches studies have been conducted with a to securely view of manage managing and share sharing private information securely using the Bblockchain technology. These studies have suggested a Bblockchain-based approaches to provide efficiency, scalability, data ownership, and systematic data lifecycles that were are the limitations of lacking in traditional access controls. More Sspecifically, these studies have introduced a new access control models, distributed hash tables, trusted execution environments, and hierarchical ID-based cryptographic mechanisms to provide reliable access control even in complex environments such as IoT Internet of Things. In this paperstudy, we present the criteria to for classifying the functional characteristics of the Bblockchain-based access control methods and derive the differentiateion between of each the several methods.

학습과 기억에서 NMDA 수용체의 역할

김승현,신경호,Kim, Seung-Hyun,Shin, Kyung-Ho 대한수면의학회 2000 수면·정신생리 Vol.7 No.1

To investigate the neurobiological bases of learning and memory is one of the ambitious goals of modern neuroscience. The progress in this field of recent years has not only brought us closer to understanding the molecular mechanism underlying long-lasting changes in synaptic strength, but it has also provided further evidence that these mechanisms are required for memory formation. Since twenty years ago, several studies for the tests of the hypothesis that NMDA-dependent hippocampal long-term potentiation(LTP) underlies learning have been reported. Also, in the recent year, data from mutant mice showed that a potential role for NMDA-dependent LTP in hippocampal CA1 and spatial learning. Although the current evidence for the role of NMDA receptor in learning and memory is not still obvious, NMDA receptor seems to act as a critical switch for activation of a cascade of events that underlie synaptic plasticity.

감정평가업에 있어서 서비스 요인과 고객만족의 관계에 대한 고찰

김승현,민규식,Kim, Seung-Hyun,Min, Gu-Sik 한국전자통신학회 2012 한국전자통신학회 논문지 Vol.7 No.3

The future of appraisal industry looks negative in the reality of change of the property market and over-competition of the field. Unless Constituent members of appraisal industry cope actively with the changing circumstances the profit structure of their company will get worse and they will finally fall behind in the competition. The best policy to survive from the changing circumstances in the limited appraisal market is to provide better service and improve its structure in order to have differential competitiveness. The purpose of this study is to describe the relation between the service factors of appraisal industry and customer satisfaction for providing more effective and high quality appraisal service. 감정평가업계도 근래 부동산 시장의 장기침체와 더불어 평가시장의 축소 및 그에 따른 과당경쟁이 심화되고 있다. 감정평가업에 있어 서비스 요인은 공정성, 객관성, 충실성, 공시업무 수행능력, 연구개발 기여도 등이 있으며 평가업계는 최상의 감정평가를 통하여 고객의 만족도를 높이고 이러한 노력은 고객의 평가를 통하여 감정평가 산업이 지속적으로 발전할 수 있게 할 것이다.

빅데이터 환경에서 분석 자원이 기업 성과에 미치는 영향

김승현,박주석,박재홍,김인현,Kim, Seung-Hyun,Park, Jooseok,Park, Jea-Hong,Kim, Inhyun 한국빅데이터학회 2016 한국빅데이터학회 학회지 Vol.1 No.1

정보기술 발전은 기업이 보유하고 있는 다양한 구조 및 비구조 데이터를 관리할 수 있게 하였다. 이러한 빅데이터 활용은 기업의 새로운 비즈니스 핵심가치로 평가 받고 있다. 본 연구에서는 빅데이터로 인해 더욱 중요하게 평가받는 데이터 자원이 기업 분석 활용에 미치는 영향을 연구하고자 한다. 최신 해외 보고서들을 살펴보면, 빅데이터 활용성과에 대한 실증 연구를 보여주고 있다. 이러한 해외 실증 연구와 비교하여 국내 기업의 빅데이터 활용 특성을 분석하고자 한다. 본 연구 결과는 향후 빅데이터 활용 기업에 적용 가능한 성숙모형 개발에 도움을 줄 수 있을 것이다. With the rapid development of information technology, we can manage not only structured data but also unstructured data. Big data environments drive new business values. This study examines the effect of analytic resources to business performance under big data environments. Recent worldwide reports showed empirical performance results of big data applications. Compared to these reports, we attempt to analyze resources of big data applications to companies in Korea. This study results in current status of big data use in Korea. and will help to develop a maturity model of big data applications.

사면붕괴 피해 예방을 위한 낙석신호등 설치 사례 연구

김승현,구호본,이종현,백용,Kim, Seung-Hyun,Koo, Ho-Bon,Rhee, Jong-Hyun,Baek, Yong 대한지질공학회 2007 지질공학 Vol.17 No.2

집중강우에 의해 주로 발생되는 절토사면 붕괴는 인적, 물적 피해를 초래한다. 한국건설기술연구원은 예방 수단으로서 위험사면을 집중관리하고 있다. 지속적인 사면관리에도 불구하고 지구환경의 변화로 절토사면의 붕괴발생 빈도는 점차적으로 증가하고 있다. 이에 대책공법 적용이 어려운 절토사면에 대하여 상시계측시스템을 설치하고 있다. 상시계측시스템의 운용은 대인 대물 피해에 대한 조치로서 활용될 수 있으나, 강우시 절토사면의 붕괴 징후를 인지하더라도 관리자가 현장관리 작업을 수행함에 있어서 시공간적 제약으로 인한 한계가 있다. 낙석신호등은 상시계측시스템을 통하여 사면 위험 징후가 발견될 시, 도로이용자에게 낙석발생에 대한 위험을 주지시키고, 붕괴시 도로관리자의 현장 도착 전까지 자동적으로 또는 수동적으로 도로를 차단시킴으로서 사면붕괴에 의한 피해를 예방하는 관리시스템의 일종이다. The failure of the road cut-slope due to heavy rains brings about lots of injuries and damage on national properties. KICT has developed CSMS system by means of prevention to manage the dangerous cut slopes. In spite of the continuous management the frequency of cut-slopes failure is increasing the past due to changes of earth-environment. KICT has installed the "Real-Time Monitoring System" on dangerous slopes. The operation of Real-Time Monitoring System is used as a positive system to reduce injuries and damages. However, Although the slope manager is aware of the signs collapsed in advance, it has temporal and spatial limits until the slope manager performs the works which are preventing the accidents. When real time monitoring system finds out an indication of slope collapse, the Rock-fall Signal Lamp System makes road-users indicated the risk of cut slopes. It is a kind of prevention system that it will minimize the damages of the properties as suspension of traffic automatically or passively.

언양-밀양 간 국도24호선 석남고개 주변부 절토사면 지반특성

김승현,구호본,이종현,김승희,Kim. Seung-Hyun,Koo. Ho-Bon,Rhee. Jong-Hyun,Kim. Seung-Hee,Kim. Jin-Hwan,Son. Young-Jin 한국방재학회 2008 한국방재학회 학술발표대회논문집 Vol.2008 No.1

울산광역시 울주군 상북면에서 경상남도 밀양시 산내면을 잇는 국도 24호선은 왕복 2차선으로 기존 도로의 선형이 매우 불량하고, 위험절토사면이 집중적으로 분포되어 있다. 2002년에는 관련기관과의 연계로 울주-밀양 간 국도 24호선의 도로절토사면에 대한 현황조사가 실시되었으며, 그 중 57개소 현장은 위험절토사면으로 분류하여 추가적인 상세 현장조사가 실시되었으며, 불연속면의 방향에 관한 다양한 정보들이 취득되었다. 2002년에는 관련기관과의 연계로 울주-밀양 간 국도 24호선의 도로절토사면에 대한 현황조사가 실시되었으며, 그 중 57개소 현장은 위험절토사면으로 분류하여 추가적인 상세 현장조사가 실시되었으며, 불연속면의 방향에 관한 다양한 정보들이 되었으며, 이에 대한 길이별, 경사별 분포현황, 불연속면 발달상태 등 여러제반 특성을 살펴 보았다. National Road No.24 connects Ulju-gun in Ulsan Metropolitan City and Milyang city in south Gyongsang Province. The width of the road is small and narrow and many of the dangerous cut slopes are distributed along the way. In 2002, the government officer carried on the brief exploration about road cut slopes, and KICT conduct a detailed additionally investigations 57 dangerous cut slope sites of them. We gained a variety of information of the each slope such as length, slope, discontinuites et al.

정신과약물의 혈중농도 측정방법 및 임상적 적용 : 항우울제를 중심으로

김승현,이민수,Kim, Seung Hyun,Lee, Min Soo 대한생물정신의학회 1995 생물정신의학 Vol.2 No.1

Therapeutic montitoring of drugs is a well established clinical 1001. However, the state of art is somewhat less advanced for psychotrpoic agents than it is for other classes of drugs, for several reasons. Most psychotropics have large volumes of distribution and achieve relatively low plasma concentrations following therapeutic doses. Many have one or more active metabolites. As a consequene, the analytical methodologies are often complex and not always reliable; well-controlled clinical studies are difficult to perform; and therapeutic ranges have been difficult to establish. Despite these limitations, prudent and selective monitoring of serum drug concentrations, particularly of the tricyclic antidepressants can be helpful in clinical management. This paper presents an overview of clinical and mothodological issues surrounding the utility of blood level measurement.