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김규식(Kyoo Sik Kim),정무혁(Moo Hyeok Chung) 대한구강악안면외과학회 1989 대한구강악안면외과학회지 Vol.15 No.2
The purpose of this report is to describe the clinical, radiographic, and histopathological findings of 41 cases of postoperative maxillary cyst(P.O.M.C.). The surgical ciliated cyst of the maxillary sinus originally reported by Gregory and Shafer in 1958 is a cyst which develops after surgical entry into the maxillary sinus, especially Caldwell-Luc operation. Besides the etiology of the P.O.M.C., its clinical course and treatment is not particular, but each cyst has various epithelial lining which reveals etiology in relation to its origin. We reviewed 41 patients diagnosed as P.O.M.C. at Dept. of Oral and maxillofacial Surgery, Seoul National University Hospital during the period from Jan. 1981 to Mar. 1989, and following results were obtained. 1. The incidence of P.O.M.C. was the highest between the age of 30 and 49 and affected 32 men and 9 women, suggesting the possibility of high incidence in men. 2. The most frequent time period between the radical operation on the maxillary sinus and the visit to hospital were from 10 to 19 year (34.1%) and 20 to 29 year (34.1%). 3. There is no significant difference in the number of each sinus involvement. The number of right sinus involvement was 22 cases(53.7%). 4. The most frequent chief complaint was the facial swelling and tenderness on the buccal cheek area. 5. Radiography showed unilocular(67.9%) and multilocular radiolucency(32.1%). 6. Histopathologically, the lining epithelium of cysts were ciliated columnar epithelium (78.0%), squamous epithelium(31.7%), cuboidal epithelium(4.9%) and columnar epithelium (4.9%). The main epithelium was ciliated columnar epithelium. 7. The surgical treatment method were Caldwll-Luc operation(28cases, 68.3%), modified Caldwell-Luc operation(8 cases, 19.5%), and cyst enucleation and primary closure 4 cases, 9.6%).
김규식(Kyoo Sik Kim),김성민(Soung Min Kim) 대한구강악안면외과학회 1997 대한구강악안면외과학회지 Vol.23 No.2
A statistical data of salivary gland tumor classification and treatment and their individual prognosis were analyzed, and their clinical, pathological characteristics were reviewed Especially malignant tumors, their individual survival rate was calculated and would like to contribute in early diagnosis and enhancement of future treatment plan. The results are as follows 1. Based on 1992 year WHO classification, salivary gland tumors were classified with 74 cases; of benign tumors(41.81%), 91 cases of malignant tumors(51.41%) and 12 cases of inflammation diseases(6.78%) as sialadenitis, necrotizing sialometaplasia. 2. In a total of 177 cases, 108 cases of female showed higher gender ratio by 1 : 156, and age distribution was 7 to 93 years with mean age was 45. The most predilected decade was 5th with 45 cases (25.42%). 3. The chief complaint diagnosed as salivary gland tumors was pain, and the sublective duration was vaned from 5 days to 20 years, with mean 10 weeks. 4. The lesion size of salivary gland tumors was vaned from superfical lesion to deep invasive lesion and their mean size was 2.18 cm. 5. The predilection site of salivary gland tumors was minor salivary gland on palate with 83 cases(46.89%), and 37 cases(20.90%) were on the parotid, 13 cases(7.3%) were on the submandibular gland 6. The five year survival rate using Kaplan-Meier product limit method ot salivary gland tumors was 61.23% and eight year survival rate was 29.12% According to stage, the five and eight year survival rate of stage I was 89.70%, 61.23%, stage II was 83.27%, 72.82%, stage III was 62.75%, 38.42%, stage IV was 54.21%, 24.31%, respectively. 7. In stage IV patients of salivary gland tumors, five and eight year survival rate of the patients with neck dissection was 62.49%, 30.28%, respectively, and this is superior to that of the patients without neck dissection with 54.39%, 26.39%. 8. The five year survival rate of the patients with cervical metastasis was 53.24% and that of the patients without cervical metastasis was 72.48 and 34.28% was that of the patients with distant metastasis. 9 According to the classifications of malignant tumors, their individual treatment and prognosis were analyzed.
抗癌劑投與가 口腔粘膜에 미치는 影響에 關한 實驗的 硏究
Kyoo Sik Kim(金圭植) 대한구강악안면외과학회 1976 대한구강악안면외과학회지 Vol.2 No.1
The purpose of this study was to evaluate the effects of Cyclophosphamide to the soft tissues of the rabbit oral cavity, especially such as palatal, buccal and tongue mucous membranes, and palatal tonsil. Nineteen yonng mile adult rabbits were used and divided into two groups like control group were injected 1 cc. normal saline solution as placebo, and experimental group were injected 30mg. Cyclophosphamide per 500Gm. body weight. Thereafter body weight and temperature were measured on 1st, 3rd, 5th, 7th, 10th, and 14th day after injections of placebo and Cyclophosphamide, and sacrificed in order to make preparations and observed histopathalogical findings. The results were drawn as follows: 1. Slightly keratinization and atrophy of oral mucosa were followed by the injection of Cyclophosphamide. 2. The administration of Cyclophosphamide caused tongue papilla atrophies such as circumvallate, fungiform and filiform papillae. 3. The lymphocytic infiltration was more prominent in the control group than that in experimental group injected Cyclophosphamide. 4. Decreasing body weight and dropping body temperature were followed in experimental group injected Cyclophosphamide.