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장무환 대한안과학회 2014 대한안과학회지 Vol.55 No.2
Purpose: To report a case of streptoococcus gordonii endophthalmitis after pneumaic retinopexy in a patient with rhegmatogenous retinal detachment. Case summary: A 40-year-old man presented with a right eye macula-on retinal detachment extending from 9 to 1 o’clock with one-clock-hour hole at 11 o’clock. After sterilizing with a Betadine solution, 0.6 cc 100% SF6 gas was injected into the vitreous through the pars plana at 11 o’clock. Two days after the injection, eyeball pain, cell and flare, and pupillary membrane developed. Under the diagnosis of endophthalmitis, vitreous tap and intravitreous vancomycin (1.0 mg/0.1 cc) and ceftazime (2.0 mg/0.1 cc) were administered. However the symptoms and signs worsened, so vitrectomy was performed, and intravitrous injections of silicone, vancomycin and ceftazime were administered. Streptococcus gordonii was identified from the excised vitreous. Visual acuity was light perception due to severe retinal necrosis. Conclusions: In cases of endophthalmitis after pneumatic retinopexy even with meticulous sterilization, a prompt operation is necessary to prevent extensive retinal damage and visual loss due to the possibility of pathogen growth other than conjunctival normal flora. J Korean Ophthalmol Soc 2014;55(2):309-311
이황화탄소 중독으로 진단받은 환자의 망막증에 대한 분석
장무환 동국대학교 경주대학 1993 東國論集 Vol.12 No.-
In order to clarify carbon disulfide retinopathy in Korea, we anlazed fluorescein angiograms of 42 patients diagnosed as CS₂ poisoning. Retinal abnormality characterized by microaneurysm was found in 66.7% of patients diagnosed as CS₂poisoning. Microaneurysms were located at posterior pole of retina and all microaneurysms were saccular microaneurysms. There was a significant correlation between prevalence of microaneurysm and CS₂ concentration(P<0.05) but, no significant correlation of prevalence of microaneurysm with CS₂ exposure duration and age was found(P>0.05).
가토안에서 녹내장 여과 수술 전 Mitomycin-C 결막하 주사가 수술 후 안압 하강에 미치는 영향
이종훈,장무환 단국대학교 1998 論文集 Vol.33 No.-
The authors measured mitomycin-C(MMC) concentration in rabbit ocular tissue with high performance liquid chromatography. The MMC concentration of conjunctiva 30 minute after a single subconjunctival injection of 0.2㎖ of 0.02㎎/㎖ MMC is similar to that after 0.4㎎/㎖ soaking method. The MMC concentraction showed a rapid decrease after a subconjunctival injection. Twenty white rabbits underwent filtration surgery, with randome allocation to one of two treatments; filtration surgery 12 hour after 20㎖ subconjuctival injection of 0.02㎎/㎖ MMC or filtration surgery with intraoperative 3 minute subconjuctival soaking of 0.4㎎/㎖ MC. Rabbits were examined at set intervals for up to 8 weeks after surgery. There were no differences in bleb area and intraocular pressure between two groups. This result suggests that the antiproliferative effect of MMC persists at least within 12hours after subconjunctival injection. If this is true, the preperative subconjunctival injection method can be a quantitative application method of MMC which reduces the possibility of ischemic filtering bleb related complications.
이창연,장무환 동국대학교 경주대학 1993 東國論集 Vol.12 No.-
It is known that meningoencephalitis is the disease usually characterized by a hstory of headache, high fever and disturbance of consciousness. Its cause is usually virus. In most cases, inflammatory reaction involve the brain diffusely, but occasionally involve brain locally. In those cases in whom inflammatory reaction involved brain locally, specific symptoms appear according to the location involved. Clinically, we can suspect the site of brain where inflammatory reaction involved, according to clinical symptoms. We experienced a case of meningoencephalitis with downbeat nystagmus implying that the inflammatory lesion involve pontomedullary junction. It was confirmed by MRI. So, we report it with review of literatures.