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      • KCI등재

        Fully Automated Molecular Diagnosis by a Novel Cartridge-based Platform

        권오원,이강호,곽봉섭,윤종수,정기수,이동규 한국정밀공학회 2016 International Journal of Precision Engineering and Vol.17 No.5

        A novel cartridge-based platform was developed to perform fully automated sample preparation, amplification, and analysis of nucleic acids. The cartridge consists of three layers: multiple reagent chambers, a mixing reservoir, and elutes and waste chambers. The fluidic manipulation and solution mixing inside the cartridge were controlled by motor systems. After loading a sample specimen, each reagent solution in the chambers of the cartridge was sequentially injected into the mixing reservoir. Extracted nucleic acids were captured by magnetic beads and transferred into a small eluates chamber. Automated sample preparation and isothermal amplification of nucleic acids for pathogenic bacteria were demonstrated in this all-in one cartridge platform. This cartridge system provides rapid and reproducible sample preparation in comparison with manual methods. In addition, real-time detection of isothermal amplification using the implemented photometric system was compared with that of using a commercial polymerase chain reaction (PCR) device. This system has the potential to become a more reliable diagnostic tool for fast detection of contagious, foodborne, and emergency point-of-care (POC) diseases.

      • SCOPUSSCIEKCI등재

        Direct-bonding bracket의 引張强度

        權五源 대한치과교정학회 1982 대한치과교정학회지 Vol.12 No.2

        As adhesive systems were improved, a great variety of bracket bases were available. The purpose of this study was to evaluate the adhesive properties of 3 types of direct-bonding brackets by testing the tensile strength. 60 noncarious premolars extracted for orthodontic treatment were used. The tensile strength was tested by Tensilon/UTM-1-10000C after 24 hours from bonding. Following results were obtained; There was no difference between the tensile strength of foil-mesh base bracket and photoetched base bracket statisstically. However, the accurate test result of plastic bracket could not be obtained due to the distortion of bracket wing during testing. Of the failure in fail-mesh base bracket and photo-etched base bracket, the combination type of failure, where part of the adhesive remained on the tooth and part on the bracket was the most common type (50%, 50%), The second type of failure occured at the bracket-adhesive interface (30%, 35%) and the last type of failure occured at the adhesive-tooth interface (20%, 15).

      • SCOPUSSCIEKCI등재

        矯正用 接着劑의 引張强度

        權五源 대한치과교정학회 1982 대한치과교정학회지 Vol.12 No.1

        The requirement of ideal orthodontic direct bonding adhesive should include longevity of bond, ability to withstand a variety of forces, resistance to the degrading effects of the oral environment, and ability to be easily removed without affecting the integrity of the enamel. The purpose of this study was to evaluate the adhesive properties of recently developed 3 orthodontic directbonding adhesives by testing the tensile strength. 75 premolars extracted for orthodontic treatment were used. The tensile strength was tested by Tensilon/UTM-1-10000C after 24 hours from bonding. Following results were obtained; The mean tensile strength of each product was higher than the maximum force (29kg/㎠) exerted on a bracket during orthodontic treatment. The tensile strength of Mono-Lok was statistically higher than Concise and Dyna-Bond, although there was no difference between the tensile strength of Concise and Dyna-Bond statistically. Of the filure, the combination type of failure (68%), where part of the adhesive remained on the tooth and part on the bracket was the most common type. The second type of failure (22.7%) occurred at the toothadhesive interface and the last type of failure (9.3%) occurred at the adhesive-bracket interface.

      • KCI등재

        저령차전자탕(猪苓車前子湯)의 기원(基源), 변천과정(變遷過程) 및 구조원리(構成原理)

        권오원,김배수,이지원,신승원,이의주,Kwon, Oh-Won,Kim, Bae-Su,Lee, Ji-Won,Shin, Seung-Won,Lee, Eui-Ju 사상체질의학회 2016 사상체질의학회지 Vol.28 No.2

        Objectives This paper investigates the origin, the progressive changes and the constructive principles of Jeoryoungchajeonja-tang(猪苓車前子湯).Methods Jeoryoungchajeonja-tang and other related prescriptions were analyzed in terms of their pathological indications, based on previous literature including 『Sanghannon(傷寒論)』, 『Keumkuaeyoryak(金匱要略)』, 『Donguibogam(東醫寶鑑)』, 『Donguisusebowon‧Sasangchobongwon(東醫壽世保元‧四象草本卷)』, 『Donguisusebowon‧Gabogubon(東醫壽世保元‧甲午舊本)』, 『Donguisusebowon‧Sinchukbon(東醫壽世保元‧辛丑本)』Results and Conclusions 1) The origin of Jeoryoungchajeonja-tang is discovered in the prescriptions for Lee-su(利水), that is, Jeoryoung-tang(猪苓湯). 2) Ohryoung-san(五苓散) introduced in 『Donguisusebowon‧Sasangchobongwon(東醫壽世保元‧四象草本卷)』progressively transformed into Shihosaryoung-san(柴胡四苓散)(『Donguisusebowon‧Gabogubon(東醫壽世保元 ‧甲午舊本)』) and ultimately into Jeoryoungchajeonja-tang(『Donguisusebowon‧Sinchukbon(東醫壽世保元‧辛丑本)』), a prescription appropriate for usage in the Mangeum symptomatology(亡陰證). 3) The Jeoryoungchajeonja-tang is composed of 10 herbs. Of these, Notopterygium incisum Ting(羌活), Aralia cordata Thunb.(獨活), Schizonepeta tenuifolia Briq.(荊芥), Saposhnikovia divaricata Schischk.(防風) make the Pyoeum(表陰) drop, and Anemarrhena asphodeloides Bge.(知母), Gypsum fibrosum(石膏) scatter the uihwa(胃火), and Poria cocos Wolf.(茯苓), Alisma canaliculatum(澤瀉), Polyporus umbellatus Fr.(猪苓), Plantago asiatica L.(車前子) facilitate urination.

      • SCOPUSSCIEKCI등재

        정상교합자의 안이평면에 대한 개개 치아의 순, 협설측경사와 근원심경사

        황해상,권오원 대한치과교정학회 1998 대한치과교정학회지 Vol.28 No.5

        교합기에 거상된 정상교합자 31명의 진단모형에서 치아FACC의 경사도를 측정하기 위해 약간 변형시킨 T.A.R.G.를 이용하여 안이평면에 대한 간 치아 FACC의 순, 협설측경사와 근원심경사를 측정하여 분석한 결과 다음과 같은 결론을 얻었다. ·상, 하악 각 치아의 FACC의 순, 협설측경사와 근원심경사를 측정하여 각각의 기준치를 얻었다. ·치아 FACC의 순, 협설측경사는 상, 하악 치열 모두에서 전방치아에서 후방치아로 갈수록 점점 설측으로 경사되는 경향을 보였다. ·치아 FACC의 근원심경사는 상악치열에서 중절치와 측절치는 거의 비슷한 경사도를 가지고 견치부위에서 후방치아로 갈수록 점점 원심으로 경사되는 양상을 보였고, 하악 치열에서는 전방치아에서 후방치아로 갈수록 점점 근심으로 경사되는 경향을 보였다. ·상, 하악 모든 치아에서 어느 한 치아의 치관 근원심경사와 순, 협설측경사는 인접치아들의 치관 근원심경사와 순, 협설측경사와 높은 순상관관계를 보였다. The purpose of this study was to obtain the angulation and inclination of FACC of all teeth to FH plane. Study models of 31 persons with normal occlusion were selected and mounted on the semiadjustable articulator for this study. Using T.A.R.G. with a little modified method, the angulation and inclination of FACC of all teeth to FH plane were measured and then the measurements were analyzed statistically. The obtained results were as follows. ·Mean, standard deviation, maximum value, and minimum value of the angulation and inclination of FACC of upper and lower teeth were obtained. ·The FACC in both upper and lower arch was progressively lingually-inclined from anterior teeth to posterior teeth. ·In the angulations of FACC of upper teeth, central and lateral incisor showed similar value. Yet, the FACC of the rest was progressively distally-angulated from the canine to posterior teeth. The FACC in lower arch was progressively mesially-angulated from anterior teeth to posterior teeth. ·The angulation and inclination of FACC of any tooth in both upper and lower teeth correlated strongly and positively with the angulation and inclination of FACC of adjacent tooth.

      • Ni-Ti矯正用線材의 超彈性에 관한 硏究

        權五源,徐惠敬,李基大 慶北大學校 齒科大學 1987 慶北齒大論文集 Vol.4 No.1

        According to the development of the techniques for tooth movement, the research on the orthodontic wires has advanced and the Ni-Ti wire is highlighted these days. The Superelasticity of Ni-Ti wires was studied in tension. The wires were tested by universal testing machine. The elastic modulus was 20×10 exp (3)kg/㎟ in Cr-Ni wires, 21∼25×10(3)kg/㎟ in Co-Cr wires and 5∼6×10 exp (3)kg/㎟ in Ni-Ti wires. The elastic modulus of Ni-Ti wires was opproximately 1/4 of Cr-Ni wires and Co-Cr wires, and the elastic limit of Ni-Ti wires was approximately 4 times of Cr-Ni wires and Co-Cr wires. The permanent strain was approximately 0.5% in stress-strain curve of Ni-Ti wires.

      • 골격성 Ⅲ급 부정교합자의 O.M.A을 이용한 상악 전방 견인 치료 효과의 장기 관찰

        권오원 慶北大學校 齒科大學 1988 慶北齒大論文集 Vol.5 No.1

        Author evaluated the effect of O.M.A. on 5 skeletal class Ⅲ malocclusion cases. The results might be as follows; 1. In all cases, forward growth of maxillary complex was accomplished. 2. In almost cases, there were rebound tendencies in maxillary and mandibular basal bone and denture relationships. 3. To minimize the relapse, it is necessary to overcorrection and stabilization after anterior traction.

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