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S&T Policy for SMEs: Lessons Learned and Implications from Korea
박영일 아시아기술혁신학회 2019 Asian Journal of Innovation and Policy Vol.8 No.3
This article puts forward the opinion of a policy expert, who had been involved in Korea's science and technology policy for 30 years, about technology policy for SMEs. This article first explains why technology policies for SMEs are needed, and from what point of view. The next section looks at the current problems facing Korean SMEs, followed by the introduction of past and current polices to support SMEs. The comparison between current issues facing SMEs and past and current policies leads to lessons that can be learned. There are four lessons for the policy itself and three for the implementation of these policies. As for policy, the first four are about stages of development, concentration, R&D and diffusion, and policy mix. The latter three are policymakers, institutional building, and cooperation between ministries. This article makes four suggestions for future policy: the importance of startups’ culture, cooperation with others, infrastructure to reduce uncertainty, and policy monitoring and evaluation.
박영일,임경순,한재용,남경우,황규춘,박화춘 한국동물번식학회 1996 Reproductive & developmental biology Vol.20 No.2
The purpose of this study was to develop the diagnosis techniques for sex determination of rabbit embryos at preimplantation stage. To detect male specific sequences using polymerase chain reaction, two genes functional on sex determination including SRY and ZFX/Y genes were targeted using multiple oligonucleotide primer sets. Three of them for conserved SRY gene were used for appropriate amplification pattern, and then only one primer set #3 proved to be most efficient, showing male-specific strong signal ofamplified sequences. Using this male specific bandsfrom human, cattle, pig and mouse, the gender of rabbit was determined. As an another system for sex determination system, amplified 910bp fragment from ZFX/Y was digested with several restriction endonuclease and showed gender specific restriction fragments only by Hinf I. Using two different system for sex identification of rabbit in this study, blind tests for 17 samples was conducted and showed identical results from two different methods. And then, amplification limit of PCR reaction for template DNA was estimated using various amounts of DNA for both SRY and ZFX/Y systems, resulted as 20pg and 800pg, respectively. With this results, test for gender identification of rabbit embryos were performed using SRY derived amplification system. From total 22 embryos selected for its developmental state 18 were identified as male embryos, showing significant difference from expected sex ratio 1:1. This biased sex ratio was interpreted as to have been caused by the fact, reported by the fact, reported by several researchers, that male embryos develop more rapidly and are more resistant against the in vitro manipulation than female embryos.
박영일,조성진,김석태,Piao, Yong-Ri,Cho, Sung-Jin,Kim, Seok-Tae 한국정보통신학회 2009 한국정보통신학회논문지 Vol.13 No.10
In this paper, we propose a novel Image Encryption using MLCA (Maximum Length Cellular Automata) and CAT (Cellular Automata Transform). Firstly, we use the Wolfram rule matrix to generate MLCA state transition matrix T. Then the state transition matrix T changes pixel value of original image according to pixel position. Next, we obtain Gateway Values to generate 2D CAT basis function. Lastly, the basis function encrypts the MLCA encrypted image into cellular automata space. The experimental results and security analysis show that the proposed method guarantees better security and non-lossy encryption. 본 논문에서는 MLCA (Maximum Length Cellular Automata)와 CAT (Cellular Automata Transform)을 이용한 새로운 영상 암호화 방법을 제안한다. 먼저 Wolfram 규칙을 선택하여 규칙행렬을 구성하고 규칙행렬에 의하여 MLCA의 상태 전이행렬 T를 만든 후 암호화 하려는 영상의 픽셀 위치에 따라 전이행렬을 곱하여 픽셀의 값을 변환한다. 다음 게이트웨이 값의 설정에 따라 2D CAT 기저함수를 생성하여 MLCA 암호화한 영상을 CAT 암호화를 한다. 실험결과와 안정성 분석을 통하여 제안한 방법은 높은 암호화 수준과 무손실 암호화의 성질을 가졌음을 확인한다.
Y 염색체 특이성 DNA 분리와 단일 H-Y 항체 개발에 의한 토끼의 수정란 성 감별에 관한 연구 I. 정소를 항원으로 한 H-Y 항혈청에 의한 토끼 수정란의 성 판별
박영일,임경순,한재용,남경우,황규춘,박화춘 한국동물번식학회 1996 Reproductive & developmental biology Vol.20 No.1
This study was carried out to determine effectively the sex of rabbit embryos using H-Y antiserum. H-Y antiserum was obtained from inbred SD strain female rat which was immunized by injection of testis cell of inbred SD strain male rate into its spleen. The titer of antiserum was identified by sperm cytotoxicity test and culture of rabbit embryos with antiserum. The developed or undeveloped embryos were separated by exposure the embryos to the antiserum with H-Y antibody. Developed embryo were transferred to the recipients and sex of offspring were examined. 1. In the sperm cytotoxicity test, the rate of dead sperm showed no difference between two antisera from spleen and testis cell as antigens. It is confirmed that H-Y antibody in antiserum was absorbed by H-Y antigen in male rat spleen cells. 2. When rabbit morulae were exposed to antiserum and complement, the rate of embryos developed or arrested was 51 and 49% respectively and the rate was closely same as natural sex ratio of 50:50%. 3. When rabbit morulae were cultured for 12h in the medium containing antiserum produced by antigen of testis cell, the rate of embryos developed or arrested was 48 and 52% respectively and the rate was closely same as natural sex ratio of 50:50%. 4. Eighty rabbit embryos which were not affected by H-Y antiserum were transferred to four recipients. Two recipients were pregnant and born 13 pups among which 2 (14%) were male and 11 (86%) were female. In conclusion, existence of H-Y antibody in the serum from female rat immunized by injecting testis cell from newborn male rat to the spleen of the female rat was confirmed. When rabbitmorulae were exposed to H-Y antiserum and complement, about a half of embryos were developed to blastocysts. When the rabbit embryos not affected by H-Y antiserum were transferred, the rate of female offspring was 86%. Therefore, it was identified that most of embryos which were not affected by H-Y antiserum were female.