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      • SCIEKCI등재

        경기도 농촌지역 음료수의 미생물학적 조사연구

        박연희 한국농화학회 1979 Applied Biological Chemistry (Appl Biol Chem) Vol.22 No.3

        To investigate the potability of water from rural area of Kyung-Gi-Do, the bacteriological examination of water samples from Yong-In Gun and Hwa-Sung Gun were carried out. The results obtained can be summarized as follows: 1. The total viable cell count showed great difference between the samples; 3 samples included less than 1×10² per ㎖ and 6 samples more than 1×10⁴ per ㎖. The maximum count arrived at 1×10^5 per ㎖. 2. The existence of faecal Streptococcus was confirmed in the samples of 4 areas. 3. For the potability, only one sample was remarked as positive and all the others were judged as negative or suspect.

      • KCI등재

        Feasibility and Efficacy of Eribulin Mesilate in Korean Patients with Metastatic Breast Cancer: Korean Multi-center Phase IV Clinical Study Results

        박연희,김태용,임용혁,이근석,박인혜,손주혁,이수현,임석아,김지현,김세현,이수정,고수진,이기형,최윤지,조은경,이수이,강석윤,서재홍,김성배,정경해 대한암학회 2017 Cancer Research and Treatment Vol.49 No.2

        Purpose Eribulin mesilate was approved for the treatment of patients with locally advanced or metastatic breast cancer (MBC), who had received at least two chemotherapeutic regimens, including anthracycline and taxane. On the other hand, the efficacy and safety information of eribulin in Korean patients is limited by the lack of clinical trials. Materials and Methods In this multicenter, open-label, single-arm, phase IV study, locally advanced or MBC patients were enrolled between June 2013 and April 2014 from 14 centers in Korea. One point four mg/m2 dose of eribulin was administered on days 1 and 8 of every 21 days. The primary endpoint was the frequency and intensity of the treatment emergent adverse event. The secondary endpoint was the disease control rate, which included the rate of complete responses, partial responses, and stable disease. Results A total of 101 patients received at least one dose of eribulin and were included in the safety set. The patients received a total of 543 treatment cycles, with a median of three cycles (range, 1 to 31 cycles). The most common adverse event was neutropenia (91.1% of patients, 48.3% of cycles). The frequent non-hematological adverse events included alopecia, decrease in appetite, fatigue/asthenia, and myalgia/arthralgia. The peripheral neuropathy of any grade occurred in 27 patients (26.7%), including grade 3 in two patients. Disease control rate was 52.7% and 51.3% of patients in the full analysis set and per-protocol set, respectively. Conclusion This study demonstrated the feasible safety profile and activity of eribulin in Korean patients with MBC.

      • SCIEKCI등재

        김치의 Pediococci 에 존재하는 Plasmid DNA 분리

        박연희,조도현,류욱상 한국농화학회 1988 Applied Biological Chemistry (Appl Biol Chem) Vol.31 No.1

        Three species of Pediococci, Pediococcus pentosaceus, Pedioeoccus acidilactici and Pediococcus halophilus were isolated from Kimchi. P. pentosaceus and P. acidilactici showed inhibitory activity against Streptococcus faecalis, Pseudomonas sp., P20 and Vibrio parahaemolyticus. However, the growth of all test organisms was not inhibited by P. halophilus. Ten strains contained one to seven plasmids, ranging in size from 1 to 60 megadaltons.

      • KCI등재

        여성노인의 외모관심이 생활만족과 우울에 미치는 영향

        박연희,박미정,전선복 한국피부과학연구원 2013 대한피부미용학회지 Vol.11 No.2

        This study has investigated elderly women’s interest in appearance, life satisfaction and depression and causal relations among them. For this, data on 286 aged women living in Gwangju have been analyzed using SPSS 15.0 and AMOS 7.0. The following results were obtained. First, elderly women’s interest in appearance was high when they were young, practiced a religion and had a spouse. Second, elderly women’s life satisfaction was high when they were young, practiced a religion and had a spouse, or if they were getting financial aid from their child or the government when they were living alone. Third, a statistically significant difference has been observed in elderly women’s depression in terms of age, educational background, religion, existence of spouse, type of residence and how to raise money to meet living expenses. Among the target subjects, 35.3% were suffering from depression. Fourth, elderly women’s interest in appearance had a positive effect on life satisfaction but negative effect on depression. In addition, their life satisfaction had a negative effect on depression. Fifth, life satisfaction had a mediating effect on the relationship between interest in appearance and depression. Therefore, reducing elderly women’s depression with diverse appearance change programs which are designed to respond to their interest in appearance and improve their mental health is suggested.

      • KCI등재

        『청맥』의 제3세계적 시각과 김수영의 민족문학론

        박연희 동국대학교 한국문학연구소 2017 한국문학연구 Vol.0 No.53

        At the time of sudden rise of Nationalism in 1960s as a counter- ideology, what kind of status did the ideological category of National Literature which Kim Soo-young(金洙暎) had referred have in the circle of progressive intellectuals of 1960s, and with which perspective was it able to band together? The purpose of this paper is to examine the historical meanings of and limits to the Theory of National Literature by Kim, Soo-young in the middle of re-contextualizing Kim Soo-young as an intellectual of Cheong-maek(靑脈). The discourse of Nationalism in Cheong-maek, above all, is of great importance since it not only revealed that the treaty between Korea and Japan was the consequence according to the Asian policy of the Cold War but paid attention to the neutral project proposed in the Third World after the Bandung Conference. Kim Soo-young, one of major writers of Cheong-maek, demonstrated the aspect of a critical liberalist who resisted common ideas of Nationalism of his age by appropriating the discourse of the Third World Nationalism. 1960년대 민족주의가 대항이념으로 급부상하게 된 시기에, 김수영이 언급한 민족문학의 이념과 범주는 과연 1960년대 진보적 지식인의 좌표 속에서 어떤 위상을 차지하고 있으며, 또 어떤 시각과 연대 가능했던 것일까. 이 글은 김수영을 『청맥』의 지식인으로 재맥락화하는 가운데 그의 민족문학론이 지닌 역사적 의미와 한계를 살펴보고자 한다. 『청맥』의 민족주의 담론은 무엇보다 한일협정이 미국의 냉전아시아 정책에 따른 결과임을 밝힘과 동시에 반둥회의 이후 제3세계 지역에서 제기된 중립 프로젝트에 주목했다는 점에서 중요하다. 『청맥』의 주요 필자 중 하나였던 김수영은 『청맥』의 ‘제3세계적 민족주의’ 담론을 전유함으로써 당대 내셔널리즘의 통념에 저항한 비판적 자유주의자 면모를 보여준다.

      • KCI등재

        ‘분실된 年代’의 자기표상 - 해방기 박인환과 김수영을 중심으로

        박연희 상허학회 2009 상허학보 Vol.27 No.-

        이 논문은 해방기 모더니스트 박인환과 김수영의 문학적 성격을 2차대전 이후 냉전인식과 관련하여 재고찰하는 데 목적을 두었다. 2차대전 이후 미소의 아시아 구상에 따른 미소공동위 개최, 분단 등 냉전의 메커니즘은 정치적 영역뿐 아니라 다른 일상 영역, 특히 문학 텍스트에 반영되었다. 가령 2차 미소공동위의 재개와 결렬이 진행되었던 1947년 이후 시에서 ‘8월 15일’이 지닌 상징적 의미가 변모하는 현상을 쉽게 찾을 수 있었다. 이처럼 해방기 문학을 고찰할 때 좌우 이념적 좌표뿐 아니라 냉전 인식에 연쇄적으로 반응하는 문학자들의 내면을 주요하게 살펴볼 필요가 있다. 그것은 김기림의 경우처럼 <문학가동맹> 소속의 활동 이력을 통해 획일화하기 어려운 그의 해방기 문학적 궤적을 재검토할 여지를 준다. 김수영과 박인환은 좌우 문단의 대표적인 신세대 문학인, 곧 청록파나 전위시인군처럼 신인 계열에 해당한다. 그러나 해방 이전에 어떤 문학 활동을 하지 않았던 이들 8.15 세대들은 해방 직후 이념적 소속 집단으로부터 상대적인 자율성을 지녔다. 예컨대 김수영과 박인환은 당대 좌파 시인처럼 새로운 제국(미국)을 의식하면서도 이들과 달리 인민 주체가 아닌 실존적 자아를 통해 보다 역동적으로 냉전현실을 표현했다. 이들의 실존의 감각은 남한의 단정수립 이후 냉전의 정치적 지형이 예각화되고 한국전쟁이 암시되는 상황에서 좀더 적극적으로 드러났다. 김수영의 「웃음」과 「토끼」의 시편에서 외부 세계에 반응하는 시적 주체는 실존적 행동을 계속해서 지속적으로 보여주었고, 한국전쟁 직전 발표된 박인환의 「1950년대의 만가」와 김기림의 「문화의 운명」 등은 정치적 위기의식을 가시화하면서 실존적 자아를 내세웠다. 즉, 해방기 모더니스트들은 현대 문명을 예민하게 감지하는 그 특유의 감각으로 식민지 시대와 분단 시대, 분단과 전쟁 사이의 긴장감을 좌우 민족 표상이 아닌 실존의 감수성을 통해 해소하고 표현하였다. This thesis is an attempt to study the characteristic of modernists in Korea after World War Ⅱ. Cold War played an important role in not only political realm but everyday life including literature. For example, as Joint Committee(美蘇共同委員會) had been broken off in 1947, so changed the symbolic meaning of 8. 15 in poetry. The literature in Liberation Period was consequent upon the chain of change occurred in korean author' mentality under the impact of Cold War. It were Kim Su-Young, Bark In-hwan and Kim ki-rim who criticized the new emperial America like left wing writers but presented existentialistic subject unlike them. In short, the modernists in Liberation Period were very exceptional writers to try for dissolving the tension of colonial period/division or division/Korean War, especially by existentialism instead of the ideologies.

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