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大腸粘膜 病變의 CEA表現 및 조직비반세포 出現에 關한 硏究
朴新一,元南熙,金世民 고려대학교 의과대학 1983 고려대 의대 잡지 Vol.20 No.1
Extensive studies to detect carcinoembryonic antigen(CEA) in the blood and tissues have been reported with the slight variations according to the CEA used and various conditions. And in colonic lesions or in normal colonic mucosa, CEA positivities upto 100% were well known. The author performed an experiment to define the pattern, and intensity of CEA in colonic mucosa. Paraffin-embedded blocks of adenocarcinoma(7 endoscopy, 9 resection), nonspecific colitis(9 endoscopy), adenomatous polyp(2 endoscopy), and normal colon(9 resection) were selected. The sections were stained with peroxidase-conjugated anti-CEA antibody after deparaffin and blocking of endogenous peroxidase with 0.3% hydrogen peroxide-methanol. And to observe the mast cell and stromal metachromasia in tumor and adjacent region, toluidine blue stain was performed on resected specimens of cases of normal colon tissues and 9 cases of colonic tissue with adenocarcinoma. The results obtained are as following : 1. CEA positive reaction to anti-CEA antibody was noted in all of 9 cases of normal colon tissue(100%), 3 out of 9 cases of non-specific colitis(33.3%). 2 adenomatous polyps(100%), and 15 out of 16 cases of adenocarcinomas(93.8%). 2. Patterns of positive reaction to anti-CEA antibody of normal colon tissue, non-specific colitis and adenomatous polyps were similar; exhibiting linear positivity along the luminal borders of surface epithelium. And in adenocarcinoma, positive reaction to anti-CEA antibody were linear along the luminal border or granular in the cytoplasm in moderate(2+) intensity. 3. Distribution of the mast cells in normal colon were few in the mucosa and many in the submucosa. In carcinoma, mast cells were absent or few in cancer cell nest, but the colon tissue adjacent to cancer cell nest showed many mast cells. 4. Stromal metachromasia was evident in the zone along the host-tumor interaction in 6 out of 9 adenocarcinomas in contrast to no stromal metachromasia in 9 normal colonic tissues. And 2 out of 3 regional lymph nodes with tumor involvement showed stromal metachromasia to the contrary all of 9 cases of regional lymph nodes without metastatic lesion revealed no stromal metachromasia. The above findings suggest that CEA posisivity in colonic lesions should be expressed by pattern and intensity of the reaction, and tissue mast cell and stromal metachromasia. seems to have close relation with malignant lesion of the colon.
박신일(Park, Shin-Il),동재욱(Dong, Jae-Uk),최명진(Choi, Myung-Jin),김용수(Kim, Yong-Su) 대한건축학회 2023 대한건축학회 학술발표대회 논문집 Vol.43 No.2
The importance of constructability is required while carrying out Building projects. However, a survey found that small buildings without supervisors do not apply well constructability in the field, And suggest a checklist for project management and review to improve constructionability. The draft checklist was applied to the project being carried out by this researcher, and the final checklist was suggested. As a result, by maximizing the improvement of construction performance through project progress inspection, the orderer was able to inspect and check construction sites by stage and construction type, and its verification and impact evaluation were conducted.
成人의 先天性 巨大結腸 : Soave 術法 Soave Procedures
李勝鎭,朴新一,李泰薰,朴京鎭 中央醫學社 1975 中央醫學 Vol.29 No.6
Two typical cases of Hirschsprung's disease in a 13 year old boy and 23 year old adult who were admitted to Dept. of surgery, Korea University and treated by Soave procedure is reported. In the adult the signs and symptoms of mechanical obstruction of the small intestine and Hirschsprung's disease are virtually identical. Unnecessary exploration of adult with Hirschsprung's disease with mistaken dia?gnosis of obstruction of the small intestine can be avoided by a barium enema examination. Rectal biopsy offers the only way of making an accurate diagnosis of Hirschprung's disease. Recommended emergency treatment consists of colostomy as soon as diagnosis is established. Experience with the Soave intramural anocolostomy procedure has demonstrated that it is a safe land effective surgical treatment for Hirschprung's disease. A review of the literature in regard to cause and treatment of congenital megacolon is made.
인바운드 도시관광을 위한 성공전략: 대구광역시를 중심으로
김동준,박신일 한국엔터테인먼트산업학회 2019 한국엔터테인먼트산업학회논문지 Vol.13 No.2
This study conducted individual in-depth interviews of tourists from Taiwan, Hong Kong and Thailand who visited Daegu. According to the analysis, Taiwan's target audience conducted an interview at the Chimac Festival in July 2018 at Duryu Park and was a university student as an individual female tourist. She got the information through SNS. The accommodation was guest house and medium and low cost hotel. The main tourist attractions included Seomun Market Night Market, Eworld and Dongseongno. The meals were Anjirang Gopchang and Galbijim in Dongin-dong. Next, the Hong Kong tourist interview was held in May 2018 at the Kwandeung Festival in Duryu Park, and was an individual tourist as a man. Lastly, an interview with a Thai tourist was held in April 2018 at the Donghwa Temple Cherry Blossom Festival in Palgongsan Mountain, and he purchased a travel agent product as a man. Participants of the tour in Daegu were interested in unusual experiences such as beauty, wedding, theme parks, and restaurants that are unique to Korea. What was disappointing was that there were not enough shopping facilities, such as duty free shops, and that the table in the restaurant was inconvenient, and that there were not enough signboards by language for foreigners.