用水供給 最大化를 爲한 Rule curve 開發事例

權五憲,朴容根 忠南大學校 産業技術硏究所 1986 산업기술연구논문집 Vol.1 No.1

The rule curve is comparatively suitable to real time operation in reservoir operation. In this paper, the rule curve for the monthly operation of the Soyang which is one of the largest reservoirs in the Han river was developed as a case study. As a result, the firm water supply by the developed rule curves reached 93.9% of the optimal values and it shows the reservoir operation by this rule curve could be positive in efficiency.

외국인고용법상 사업장변경제한에 대한 헌법과 국제법상의 문제점 및 법적 개선방안

박용근 전북대학교 동북아법연구소 2012 동북아법연구 Vol.5 No.3

국내 Human Immunodeficiency Virus(HIV) 감염자와 정상인의 면역학적 표지인자 비교연구

신영오,류재천,최병선,박용근 THE KOREAN SOCIETY FOR BIOMEDICAL LABORATORY SCINE 1995 Journal of biomedical laboratory sciences Vol.1 No.1

HIV감염자는 질병의 진전에 무관하게 감염 후의 경과시기에 따라서 CD4 T림프세포등 각종 면역상태를 나타내는 표지가 변한다. 따라서 HIV감염자의 질병진전을 예보하기 위하여서는 정기적으로 CD4등 각종표지를 측정하여 감염자의 질병상태를 monitoring하게 된다. 그러나 이러한 수치를 감염자관리에 적용하기 위하여서는 우리나라 일반인의 정상치를 파악하여 이를 지표로 해야하므로 국내정상인의 각종면역치에 대한 조사가 요구된다. 현재의 기준으로는 500이하로 떨어질 때에는 예방차원에서 AZT를 복용하게 되며 200이하로 떨어지면 질병의 유무에 관계없이 환자로 관리하게 된다. 본연구에서는 한국인 185명의 감염자와 140명의 비감염자에 대하여 정기적으로 CD4 및 CD8T 림프세포와 CD4/CD8비를 측정하였다. 시험은 Flow cytometer(Facstar)를 이용하여 각각의 CD 분자에 대한 모노크로날 항체를 이용하여 2중혈광색소염색방법으로 측정하였다. HIV감염자의 CD4-T림프세로 절대수 및 백분율은 각각 462 및 18.2%이었는 반면, CD8의 수치는 1,170 및 47.0%이었다. 또한 CD4/CD8비는 0.43이었다. 이와는 대조적으로 비감염자의 경우, 한국인의 CD4의 평균세포수는 886, 백분율은 32.9%이었으며, CD8 세포수는 730, 백분율은 26.8 그리고 CD4/CD8비는 1.31이었다. 외국인과 한국인과의 면역지표수치를 비교하였을 때에 CD4세포수와 백분율, CD8의 백분율에서는 현저한 차이가 없었으나 외국인 비감염자의 경우 CD4백분율이 43.6%, CD8 T림프세포의 절대수가 560으로 한국인과 약간의 차이가 있었다. 따라서 HIV감염자관리를 위한 면역지표측정시험에서의 각종수치의 정확한 해석을 위하여서는 한국인 비감염자수치를 고려해야할 것으로 판단된다. Several studies showed that the immunological factors such as CD4+ cell number, CD4%, CD8+ cell number and CD4/CD8 ratio and the serological factors such as β²-microglobulin(β²-MG), neopterin, soluble CD4, and soluble CD8 are related to the risk of development of AIDS. Especially, the CD4+ cell counts have been used to monitor progresson of HIV disease, to stratify, and to follow patients in clinical trials. Recently, the Centers for Disease Control and Prevention(CDCP) in USA has made the CD4+ cell count as a part of the classification of HIV disease. It is composed of 3 categories such as 1, 2, and 3 which asr ≥500/㎣, 200/㎣ ≥and <500/㎣, and < 200/㎣, respectively. In this study, to estimate the differences of immunological factors between HIV-infected and normal human groups in Korea, CD4+ T and CD8+ T cells, and the CD4/CD8 ratio were measured in 185 HIV-infected subjects and 140 healthy adult subjects. The lymphocyte subsets such as CD4+ T and CD8+ T were analysed by flow cytometer(FACStar) with two-color immunofluorescent stain using monoclonal antibodies such as anti-CD4 and anti-CD8 antibodies. The absolute numbers and percentages of CD4+ T and CD8+ T and the CD4/CD8 ratio of HIV infected persons were 462±277/㎣, 18.2±7.7%, 1,170±534/㎣, 47.0±10.6% and 0.43±0.26 whereas those of uninfected persons were 886±299/㎣, 32.9±7.0%, 730± 259/㎣, 26.8±6.4% and l.31±0.46(P<0.01). In addition, estimating the reference values of peripheral blood lymphocyte subsets of Korean, the absolute numbers and percentages of CD4+ T and CD8+ T and the CD4/CD8 ratio of 140 healthy adults persons were measured and compared with those of foreigners. The reference ranges of CD4+ T cells, CD8+ T cells, CD4%, CD8%, and the CD4/CD8 ratio and 1.31t0.46, respectively. The significant differences were not observed when compared with those of foreigners. However a little difference was observed in the percentages of CD4+ T and the absolute numbers of CD8+ T between the normal values of Korean and those of foreigners were 43.6±8.9%, 560±230/㎣. This result can also be useful as a basic data for the treatment and surveillance of HIV-infected patients in Korea.

자발성 뇌출혈 환자에서의 다중도관을 이용한 뇌정위적 수술의 평가

박용근,안영민,안영환,윤수한,조기홍,조경기 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.10

The treatment modality of patients with spontaneous intracerebral hematoma is still controversial. With remarkable development of CT-guided stereotactic techniques. stereotactic evacuation is preferable to conventional craniotomy due to local anesthesia and minimal brain damage. We reviewed 60 patients with hypertensive intracerebral hematoma. treated with CT-guided stereotactic aspiration and conventional craniotomy from Jan. 1995 to Dec. 1995. The patients were divided into three groups. Group I included the patients who had hematoma less than 30cc in volume and treated stereotactically using a single catheter. Group Ⅱ was consisted of patients who had hematoma more than 30cc and treated stereotactically using 2 or more catheters. Group Ⅲ was composed of the patients who showed neurologically rapid progression and treated with conventional craniotomy. We compared the results of the three groups of therapeutic modalities and made conclusions. Most of the spontaneous intracranial hematomas were removed completely within 5 days by the stereotactic method. This method was feasible to the patients. who had large volume of hematomas using multiple catheters.

<재정분권 실현을 위한 지방세 부과 , 징수의 법적문제>에 대한 토론문

박용근 한국지방자치법학회 2019 한국지방자치법학회 학술대회 자료집 Vol.70 No.-

진주 가호동유적

박용근,이주영,성원순 한국고고학회 2009 한국고고학전국대회 발표문 Vol.- No.33

고형지질마이크로스피어를 이용한 방출제어형 국소마취주사제의 제제설계 및 평가

박용근,이종화,김동우,윤재남,전일순,이은미,이계원,지웅길 대한약학회 2003 약학회지 Vol.47 No.2

Local anesthetics are used to reduce pain, but they are so frequently injected to patients. So, we prepared lidocaine solid lipid microspheres (SLM) as long acting abdominal injection using spray drying method and evaluated drug entrapment, particle size, SEM, zeta potential and in vitro and in vivo drug release pattern, The particle sizes of SLM were 30∼100$\mu$m and it is enough to inject into abdominal tissue. The entrapment efficiency of SLM was over 95% as spray drying method. Surfactant and PC decreased the burst effect by 20∼30%. In in vivo test, C-6 showed controlled release concentration profile in plasma for 8 days and C-5 sustained longer than we expected.

[기술발표] 2구 일체 투입구형 계량 기반 RFID 음식물 쓰레기 종량제 시스템

박용근 한국폐기물자원순환학회 2011 한국폐기물자원순환학회 학술대회 Vol.2011 No.1

척수병증을 유발한 경추부 활액성 낭종 1례

박용근,전병윤,김영수 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.7

Synovial cysts occur typically in periphsral joints and tendon sheaths Thsy rarely occur intraspinally Recently we have experie'iced a case of extradural synovial cyst in the cervical spine. causing a mysiopathy which results in pTogressive motor weakness and sensory change The case is therefore presented with rview of literatures

Improvement of Osteoporosis Medication after Multimodal Intervention in Patients with Hip Fracture: Prospective Multicenter Study

박용근,남광우,김상림,박민석,김상재,하용찬 대한골대사학회 2018 대한골대사학회지 Vol.25 No.2

Background: The authors had earlier conducted a retrospective cohort study from 2008 to 2011 in Jeju Island, among 945 hip fracture patients above 50 years of age. Of these 945 patients, 344 patients (36.4%) underwent a bone mineral density test and 218 patients (23.1%) received treatment for osteoporosis. The purpose of this study was to determine whether a patient education program could improve osteoporosis management after hip fracture. The data of the previous study was used for comparison. Methods: From November 1, 2014 to September 30, 2015, 190 patients above 50 years of age who were admitted for hip fractures at six different hospitals, were enrolled in the present study. During the hospitalization period, patients underwent education sessions and were provided brochures. Patients were evaluated for diagnosis and treatment of osteoporosis at six months after discharge and were followed-up for at least a year. Results: Of the 222 patients with hip fractures, 190 patients (37 men, 153 women) were enrolled at six hospitals in 2015. Dual energy X-ray absorptiometry was performed on 115 patients (60.5%) and 92 patients (48.4%) were prescribed medication for osteoporosis at the time of discharge. A total of 43.7% and 40.2% of the patients were found to be compliant with osteoporosis medication at 6 months and 12 months follow-up respectively. Conclusions: This interventional multicenter study demonstrated that a patient education program in patients with hip fractures can improve compliance to osteoporosis medication up to 12 months of follow-up.