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박재용,황승민,임민규,오영규,박재용,한석영 한국공작기계학회 2009 한국공작기계학회 춘계학술대회논문집 Vol.2009 No.-
This paper presents a reliability-based topology optimization (RBTO) using bi-directional evolutionary structural optimization (BESO). An actual design involves uncertain conditions such as material property, operational load and dimensional variation. Deterministic topology optimization (DTO) is obtained without considering of uncertainties related to the uncertainty parameters. However, the RBTO can consider the uncertainty variables because it has the probabilistic constraints. In this paper, the reliability index approach (RIA) is adopted to evaluate the probabilistic constraint. RBTO based on BESO starting from various design domains produces a similar optimal topology each other. Numerical examples are presented to compare the DTO with the RBTO.
박재용,임민규,오영규,박재용,한석영,Park, Jae-Yong,Im, Min-Kyu,Oh, Young-Kyu,Park, Jae-Yong,Han, Seog-Young 한국생산제조학회 2010 한국생산제조학회지 Vol.25 No.5
Reliability-based topology optimization (RBTO) is to get an optimal topology satisfying uncertainties of design variables. In this study, reliability-based topology optimization method is applied to the inner reinforcement of vehicle's hood based on BESO. A multi-objective topology optimization technique was implemented to obtain optimal topology of the inner reinforcement of the hood. considering the static stiffness of bending and torsion as well as natural frequency. Performance measure approach (PMA), which has probabilistic constraints that are formulated in terms of the reliability index, is adopted to evaluate the probabilistic constraints. To evaluate the obtained optimal topology by RBTO, it is compared with that of DTO of the inner reinforcement of the hood. It is found that the more suitable topology is obtained through RBTO than DTO even though the final volume of RBTO is a little bit larger than that of DTO. From the result, multiobjective optimization technique based on the BESO can be applied very effectively in topology optimization for vehicle's hood reinforcement considering the static stiffness of bending and torsion as well as natural frequency.
박재용,송영주 한국웰니스학회 2017 한국웰니스학회지 Vol.12 No.3
Purpose: The purpose of this study was to assess the hip and ankle muscle function of the involved and the non-involved (unaffected) sides in Hapkido practitioners with chronic ankle instability. Subjects and Methods: Hapkido practitioners was conducted in males (n=8) with unilateral chronic ankle instability, who were aged in their 20s. Mann-Whitney were used to analyse the differences between the non-injured and the injured side in Hapkido practitioners with chronic ankle instability. A statistical significance level (α) of .05 was used. Results: The hip adductor muscle function of the involved side was significantly poorer than that of the non-involved side 30°/sec [peak torque% body weight (p <.05)] and 180°/sec [peak torque and peak torque% body weight (p <.01)]. The ankle evertor muscle function of the involved side compared to the non-involved side in all variables (peak torque, peak torque% body weight, and total work) were significantly less on 30°/sec and 120°/sec (p <.01). The ankle invertor muscle function of the involved side compared to the non-involved side in peak torque% body weight were significantly less on 30°/sec (p <.01). In addition, the ankle plantar flexor muscle function of the involved side was significantly worse than that of the non-involved side at 30°/sec (peak torque, peak torque% body weight, and total work [p <.01)] and 120°/sec [total work (p <.01)]. Conclusions: This study provides evidence that chronic ankle instability needs a comprehensive therapeutic approach to help prevent recurrence by addressing mechanical and functional instability.
박재용 대한상부위장관ㆍ헬리코박터학회 2020 Korean Journal of Helicobacter Upper Gastrointesti Vol.20 No.1
Recently, many studies have reported the potential association of Helicobacter pylori (H. pylori) with various extragastric diseases. H. pylori, a major component of the gastric microbiota, is in symbiosis with humans. It is, therefore, assumed to potentially influence immune homeostasis in humans to some extent. There are several reports highlighting the possible association of H. pylori with allergic diseases. However, these were mainly based on cross-sectional or epidemiological studies. With a greater emphasis on the effects of human microbiota on host immunity and disease development, studies have attempted to explain the association between H. pylori infection and allergic diseases. Nevertheless, no concrete evidence for a causal relationship has been clearly demonstrated yet. The association of H. pylori infection with autoimmune disorders has also been reported in the literature. It has been hypothesized that environmental triggers act on genetically vulnerable hosts, leading to autoimmune disorders. The role of H. pylori infection as one of the triggers in autoimmune diseases has been explored previously. However, the results were conflicting and indistinct with respect to most autoimmune diseases. Similar findings were also detected in skin disorders where H. pylori infection was deemed to be a causative factor. The role of H. pylori in majority of the immune-mediated disorders or skin disorders remains controversial. In this review, the association of H. pylori with various immune-mediated disorders and skin disorders is discussed. The epidemiological, serological, and experimental evidences relevant to the aforementioned association are also addressed.