농촌 주민들의 심전도 소견에 관하여

서석권,윤능기,이성관 대한보건협회 1985 대한보건연구 Vol.11 No.2

SJAS로 측정한 A 형행동양상과 사회인구학적인 변수

서석권 啓明大學校 醫科大學 1988 계명의대학술지 Vol.7 No.2

To investigate the sociodemographic variables to enhance and maintain the Type A behavior Pattern (TABP) socially by comparing the differences of sociodemographic variables of the A-B Behavior Pattern measured by the Student Jekins Sctivity Survey(SJAS, short form), the authors conducted a questionnaire survey using a medical school undergraduated(413) as a study population April to May, 1988. The cut-off point which divides into A-B Behavior Pattern was ±1 standard deviation of the total score of the SJAS(≤3, ≥10), resulting in 61 TABP & 82 Type B Behavior Pattern (TBBP). The reliability coefficient of the total score of the SJAS measured by Cronbach's alpha was 0.72. In the family environments, there were no difference in the place raised, deceased father, age of father between TABP and TBBP. The Hollingshead's socioeconomic status index which was dichotomized by median value showed a statistically significant difference; The high index group was 47.4% in TABP and 65.8% in TBBP(P=0.03). TABP showed little difference in age, sex, and proportion of those who have a religion compared with the TBBP. The proportion of those who suffered a failure more than once academically after entering the medical school was 19.7% in TABP and 35.4 in TBBP which was statistically significant(P=0.04). TABP was not different from TBBP in the habits of smoking and alcohol consumptions. The smaller proportion of failure suffered in TABP than TBBP could explain the competitive and hard-driving aspects of the TABP and the socioeconomic status may exert a different influence on the socialization pressure leading to the formation of the TABP in the early life from the American's.

말초혈액 벽혈구수와 관상동맥 질환의 위험요인과의 관계

서석권,이무식,박종원,전종찬,윤능기,이충원 啓明大學校 醫科大學 1994 계명의대학술지 Vol.13 No.1

This study was attempted to assess the relationship between peripheral leukocyte count and cardio-vascular risk factors in 2,883 male(66.4%) and 1,460 female(33.6%) visitors to a health examination center of a university hospital located in Taegu March to December 1992. Mean age of male was 43.6 and female 45.5 Average leukocyte count was 7.5×10³/ ㎕(S. D. 2.1) in male and 6.5×10³/㎕(S.D. 1.7) in female, respectively. Statistically significant differences by sex were noted in age, triglyceride, hige-density lipoprotein cholesterol, and leukocyte count(P<0.001,respectively). The distribution of leukocyte count was approximately lognormal. Leukocyte count was higher in male than in female in all age groups and increased with age in both sexes. Strong positive correlation between leukocyte count and triglyceride was found in both sexes. Total cholesterol, body mass index, age and low-density lipoprotein cholesterol had positive correlation while high-density lipoprotein cholesterol had negative correlation with leukocyte count in male. And a similar pattern was also found in female, but the magnitude of correlation was stronger than in male particularly triglyceride. Linear trend test showed dose-response relationships with body mass index, total cholesterol, low-density lipoprotein cholesterol, triglyceride and high-density lipoprotein cholesterol in both sexes(P<0.01). Stepwise multiple regression of leukocyte count selected triglyceride, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, age and body mass index in male, while it did triglyceride and body mass index in female. These results suggested that there be associations between leukocyte count and conventional risk factors of coronary heart disease and leukocyte count may play an indirect role in the pathogenesis of coronary heart disease.

Epidemiological survey of Paragonimus westermani among residents in Ulchin county, Kyungpook Province, Korea

徐錫權,朱鍾潤 啓明大學校 醫科大學 1990 계명의대학술지 Vol.9 No.2

肺吸蟲 浸潤地로 알려진 慶北 蔚珍郡 住民들에 있어서 肺흡蟲 最近 感染狀을 알아보기위해 1989年 3月부터 1990年 6月까지 蔚珍郡內 10個面 43個部落 住民 1.262名을 調査對象으로 皮內反應을 調査함과 同時에 調査地域에서 採集한 가재에서 本蟲 被襄幼蟲 感染狀을 調査하였다. 調査마을 43個 가운데 22個마을 住民들에 있어서 肺吸蟲 陽性者가 檢出되었으며, 그 率은 最高 29.8%, 最低 1.3%로 마을마다 큰 差異를 나타내었다. 住民 1.262名中 皮內反應 陽性者는 146名, 그 率은 10.2%였으며, 性別感染率에 있어서는 男性에서는 12.4%, 女性에서는 10.2%로 兩者間에 有意的 差를 認定할 수 없었다. 皮內反應 陽性者 146名 가운데 18名은 喀痰儉査에서 蟲卵을 檢出할 수 있었으며, 3名은 大便檢査에서만 蟲卵을 檢出할 수 있었고, 9名은 喀痰 및 大便檢査 모두에서 蟲卵을 發見할 수 있었다. 年令群別 感染率에 있어서는 0-9歲群에서는 6.4%였으며, 年令이 많이질수록 그 率도 增加하여 30-39歲群에서는 最高値 31.7%를 나타내었다. 調査地域에서 授集한 가재에서 肺吸蟲 被襄幼蟲 檢出率은 地域에 따라 큰 差異를 나타내었고, 가재 部位別 寄生狀은 頭胸部(69.1%), 아가미(25.2%), 및 肝(5.5%) 順이었으며, 가재 한마라當 肺吸蟲 皮襄幼蟲數는 1.8個였다. 調査地域 住民들에 있어서 肺吸蟲에 對한 保建知識 및 中間宿主 攝取에 關한 設問書 調査에서는 皮內反應 陽性者와 陰性者사이에 뚜렷한 差를 認定할 수 없었으며, 肺吸蟲 感染에 關한 知識을 얻을 수 있었던 保建敎育 媒體의 種類는 學校敎育을 통하여 알게 되는 경우가 41.5%로 가장 높았으며, 다음은 라디오 텔레비젼(25.5%), 保建所(13.4%) 및 病院(12.5) 順이었다. 以上의 成績으로 미루어보아 慶北 蔚珍郡은 肺吸蟲 流行地域으로 남아 있을뿐만 아니라 住民들에서의 肺吸蟲 感染率은 아직도 높음을 알았다.

산업장 흡연자 관리를 위한 행동의 단계적 변화론 모델의 적용 방안

서석권,이승훈 啓明大學校 醫科大學 1998 계명의대학술지 Vol.17 No.2

흡연은 폐암, 만성 호흡기 질환 및 심혈관계 질환 등 인체에 많은 영향을 일으킨다고 보고되고 있다. 산업장내 근로자들은 분진, 유기 용제, 중금속 등과 같은 수많은 직업성독성 물질에 폭로되고 있기 때문에 이들 중 흡연자 관리는 예방의학적 및 산업 의학적으로 매우 중요한 의미를 지니고 있다. Prochaska가 개발한 행동의 단계적 변화론(transtheoretical model)은 흡연 습관의 단계에 따라 총 6단계 (계획전, 계획, 준비, 실천, 유지 및 완료 단계)로 구분되어 있고, 행동양상의 변화 과정 (processes of change)에는 의식 증가, 자극 조절, 자기 및 환경 재평가 등이 있다고 한다. 산업장 보건 관리 사업은 1981년 산업 안전 보건법에 의해 의사 및 간호사들이 직접 한 달에 한 번씩 정기적으로 산업현장을 방문하여 일차 의료를 제공하는 보건 의료 서비스이다. 흡연자들의 지속적인 추적관리가 가능하다는 점에서 의사 및 간호사가 단계별 행동 변화론 모델을 산업장 흡연자들에게 적용할 경우, 차 후에 보다 포괄적이고도 지속적인 보건의료 서비스를 제공할 수 있을 것으로 사료되어진다. Cigarette smoking is causally associated with the development of lung cancer, chronic obstructive pulmonary disease, and several kinds of cardiovascular disease. Not a few smokers are aware of the influence of smoking on their health, but they can not easily stop. Smokers at the industrial settings are of great concern because they are simultaneously exposed to a variety of workplace hazards such as dusts, metal fumes, and solvent vapors. In compliance with the 1981 Korean Industrial Safety and Health Act, the Ministry of Labor designated Occupational Health Centers to provide periodic health care services to the employees of companies. To achieve more systematic interventions for smokers, we suggest occupational health professionals in these centers conduct team approaches with an application of the transtheoretical model. The transtheoretical model that has been developed from the psychotherapy literatures conceives behavioral changes as a process involving progress through a series of six changes: precontemplation, contemplation, preparation, action, maintenance, and termination. Based on this model, we recommend each center uses the stage-matched strategies with the team approaches between occupational health nurses. To improve the efficacy of the intervention, the company should also try to work cooperatively with Occupational Health Centers. The reduction of smoking rates in workplaces would lead to increased productivity as well as workers' health promotion in the future. In this regard, we would like to present a proper way of applying the transtheoretical model to smokers in workplaces.

농촌 노인에서의 농부증과 우울정도와의 관련성

서석권,양선희,이미영,신동훈,이무식 啓明大學校 醫科大學 1998 계명의대학술지 Vol.17 No.3

농부증은 그 자체로서 하나의 질병은 아니나, 우리 나라 농촌 지역에서 농부증의 유병율이 20∼40%에 이르는 것으로 보고되면서, 농부증의 원인에 대한 여려 조사 연구가 있어 왔다. 과거에는 농부증이 농촌 지역에 국한되어 발생하는 특수한 농부들의 질환이라고 하였으나 최근에는 농부증의 원인으로는 스트레스가 지목되고 있으며, 정신적인 스트레스가 증가할수록 농부증의 위험도 증가되는 것을 h보고되고 잇다. 이에 본 연구는 경상북도 김천시 조마면에 거주하는 60세 이상의 농업협동조합 조합원 및 그 가족을 대상으로 농부증에 영항을 주는 요인 및 농부증과 우울 성향과의 관련성을 밝혀 보고자 하였다. 60세 이상을 대상으로 한 본 연구의 결과에서 농부증에 영향을 주는 요인으로는 성별과 우울 성향 뿐이었으며, 성별보다는 우울 성향이 더 큰 영향을 미치는 것으로 평가되었다. 또 한 농부증의 가장 빈도가 높은 증상인 요통, 손발저림, 어깨결림 중 어깨결림, 요통이 우울 성향과 유의한 관련을 보여주었으며, 그 외 농부증의 증상 중 호흡곤란과 어지러움이 우울 성향과 밀접한 상관관계를 가지는 것으로 나타났다. 따라서, 본 연구결과는 농부증에 영향을 미치는 요인으로 성별을 제외하면 우울 성향뿐이며, 농부증의 증상 항목 중에서 네 가지 항목이 우울성향과 밀접한 관련성이 있음을 보여줌으로서 농부증이 농촌 지역에 국한된 특수한 질환이라기보다는 정신적 우울 성향에 의한 복합적인 증상일 가능성을 제시해 준다. Farmers' syndrome is so important health problem of rural areas in recent years. The study was conducted to elucidate the relationship between farmer's syndrome and the depth level of depression in rural elderly. This study was done in the selected 4 villages in Kimchun County of Kyungbuk Province. The subject was the resident that 202 adults above 60 years of age. The Questionnaire of interview included sociodemographic data, 8 components of farmer' syndrome and 21 items of Beck Depression Inventory(BDI). The data was interpreted by frequency analysis, chi-square test, t-test, oneway ANOVA, correlation analysis, and multiple regression. The results were as followed : 1. The total score of farmer's syndrome was evidently higher in the female elderly and the total BDI score was higher in small family size. 2. Among the eight symptoms of farmer's syndrome, lumbago, shoulder stiffness and numbness of limb were most common symptoms of farmer's syndrome. Among the most common three symptoms, two symptoms were related with BDI score tightly. 3. Except sex difference, farmer's syndrome was significantly correlated with BDI score and four symptoms had statistically significant relationship with BDI score. Therefore, depressions is most important cause of farmer's syndrome.

A형행동양상과 사회적인 지지 및 혈청 총콜레스테롤과의 상관성

서석권,구은수,이충원 啓明大學校 醫科大學 1991 계명의대학술지 Vol.10 No.1

The objective of the study was to determine whether there are relationships of type A behavior pattern(TABP) and social support to serum total cholesterol and interaction between TABP and social support. The sample(N=389) was accrued by the author's convenience from those who had visited the depatment of family medicine of the Dongsan Medical Center to take a periodic medical examination by a preventive program of medical insurance for the public officials and private school teachers and employees, from whom 24 excluded due to missing questionnaire items and drugs or conditions which can influence the serum total cholesterol abnormally. Male were 235(64.4%) and mean ages were 40.1(males) and 29.1(females). After inclusion of the control variables, body mass index(Quetelet index), age and subjective ratings of dietary fat intake in stepwise multiple linear regression models by gender, TABP measured by Framingham Type A Scale(FTA) was not related to serum total cholesterol in both sexes. Of the 3 scoial support indices measured by Hanson's avilability of material and informational support(MIS), adequacy of Framingham Type A Scale(FTA) was not related to serum total cholesterol in both sexes. Of the 3 social support indices measured by Hanson's availability of material and informational support(MIS), adequacy of emotional support and total score summed up 3 indices were selected in males(R2= 0.164, 0.161, 0.171, respectively, P<0.001), but none of the indices were selected in females. The only interaction term selected was between TABP and MIS whcih was help in females(R2=0.190, P<0.11).

일부 인쇄공들의 혈중 및 모발증 연함량

서석권,윤능기 啓明大學校 醫科大學 1989 계명의대학술지 Vol.8 No.2

For the purpose of obtaining on effective biological data, study to evaluate the health consequence of lead absorptioin was conducted using printing industry workers in Taegu City from July 1 to 31, 1989. The study population was the 64 lead-exposed workers and 31 non-exposed workers who were working in the printing industry. The lead indices subjected to this study were as follows;p blood lead(PbB0, Hemoglobin(Hb), lead in hair(PbH). Blood lead(PbB) and hair lead(PbH) concentrations were estimated using the Atomic Absorption Spectrophotometer(IL 551) equipped with furnace Atomizer(IL 755). The results obtain were as follows: The mean value of blood lead level were 25.58±7.21㎍/100ml and 22.95±4.80㎍/100ml in lead-exposed workers and controls, respectively and was statisically significant difference(p<0.05). The mean value of lead level in hair were 15.01±6.31㎍/g and 11.41±5.74㎍/g in lead-exposed workers and controls, respectively(p<0.01). The mean value of hemoglobin were 15.10±0.93 g/100ml and 14.67±1.03g/100ml in lead-exposed workers and controls, respectively(p<0.01). In lead-exposed workder, the correlation between PbB and PbH (r=0.0953), Hb(r=-0.2108) was no statistically significant difference, respectively and there was staatistically significant correlation between PbH and Hb (r=-0.3064), work duration(r=0.3658), respectively(p<0.01).

농업종사자(農業從事者)의 혈장(血漿) Cholinesterase 치(値) 변화(變化)에 관(關)한 연구(硏究)

서석권,황인담,Suh, Suk-Kweon,Hwang, In-Dam 한국농촌의학지역보건학회 1983 농촌의학·지역보건 Vol.8 No.1

살충제(殺蟲劑)의 주종(主宗)을 이루는 유기인제(有機憐劑)에 의한 만성중독(慢性中毒)의 예방(豫防)을 위(爲)한 기초자료(基礎資料)를 얻고, 또한 농업종사자(農業從事者)의 혈장(血漿) cholinesterase의 정상치(正常植)를 추정(推定)하고저 전라북도(全羅北道) 정읍군(井邑郡)의 일부(一部) 농업종사자(農業從事者)에 대(對)한 혈장(血漿) cholinesterase 치(植)를 Takahashi의 Micro- method로 측정분석(測定分析)한바 다음과 같이 요약(要約)된다. 1) 농약살포전군(農藥澈布前群)의 혈장(血漿) cholinesterase 치(植)는 $7.60{\pm}1.74{\mu}M/20{\mu}{\ell}$/hr.였고, 살포후군(撒布後群)에서는 $6.23{\pm}1.59{\mu}/20{\mu}{\ell}$/hr.로서 살포전군(澈布前群)보다 $1.37{\mu}M/20{\mu}{\ell}$/hr.가 낮게 나타났다 (P < 0.01). 2) 농업종사자(農業從事者)의 정상(正常) 혈장(血漿) cholinesterase 치(植)의 95% 신뢰구간(信賴區間)은 $7.30-7.90{\mu}M/20{\mu}{\ell}$/hr.이었다. This study was carried out to obtain the basic data for the prevention of chronic poisoning by organic phosphorous pesticides and to estimate the normal range of plasma cholinesterase activity level for Korean agricultural workers. The 285 agricultural workers were randomly selected for the study in Jungup Gun, Jeonbug Province, 135 persons of them were tested in the period of pre-exposure of organophosphorous pesticides (April 1981) and rest of them were tested after exposure(August 1981). Cholinesterase activity levels were measured by the Micro-method of Takahashi Hiroshi. Major findings are as following: 1) There is significant difference in plasma cholinesterase activity levels between the pro-exposed and post exposed group(p > 0.01). Mean values of plasma cholinesterase activity levels were $7.60{\pm}1.74{\mu}M/20{\mu}{\ell}$/hr. in the pre-exposed group and $6.23{\pm}1.59{\mu}M/20{\mu}{\ell}$/hr. in the post-exposed group. 2) Plasma cholinesterase activity in Korean agricultural worker could be estimated $7.30-7.90{\mu}M/20{\mu}{\ell}$/hr. with 95% confidence interval.

톨루엔 취급자들의 면역기능에 관한 조사

서석권,이종영,이승훈,Suh, Suk-Kwon,Lee, Jong-Young,Lee, Seoung-Hoon 대한예방의학회 1992 예방의학회지 Vol.25 No.2

톨루엔의 폭로가 인체의 면역기능에 미치는 영향에 대해 알아 보기 위하여 톨루엔 취급자 21명과 일반 사무직 근로자 12명에 대하여 혈액 및 말초혈액 림프구의 subpopulation에 대하여 조사하였다. 혈액소견은 두 군 모두 정상범위로 통계적으로 유의한 차이가 없었다. CD4 림프구 세포의 비율은 두 군에서 유사하였으며 T와 B림프구 및 CD8 림프구 세포의 비율은 폭로군에서 약간 낮았으나, 두 군 모두 정상 범위로 통계적으로 유의한 차이가 없었다. 폭로군에서 T 림프구 및 CD4 세포의 비율은 근무기간이 길수록 통계적으로 유의하게 증가하였다(P<0.05). 본 연구의 폭로군에서 림프구의 subpopulation은 전반적으로 비폭로군보다 약간 낮은 경향은 있었지만, 정상범위에 해당하였으므로 톨루엔에 폭로되었을 때 인체에 대한 면역기능은 큰 영향이 없는 것으로 생각되어진다. 그러나 폭로기간에 따라 면역기능이 변동하는 것으로 보아 톨루엔이 인체의 면역기능에 미치는 영향에 관한 지속적인 연구가 이루어져야 하겠다. To assess the immunological function of toluene exposed group, the proportions of T lymphocyte, B lymphocyte, CD4 cell, CD8 cell, the ratio of CD4 to CD8(CD4/CD8) in peripheral blood were measured on twenty-one toluene exposed workers and twelve healthy workers who did not have previous history of toluene exposure. In addition, to evaluate the present status of toluene exposure, urinary hippuric acid concenturations were measured in exposed group. The mean concenturation of urinary hippuric acid was 2.84 g/creatinine g in exposed group. The proportions of T lymphocyte, B lymphocyte, CD8 cell and CD4/CD8 of exposed group were slightly lower than non-exposed group except the proportion of CD4 cell which was similar in both groups. But these differences were not statistically different in both groups. The proportions of T lymphocyte and CD4 cell were significantly correlated with the length of duration in exposed group(P<0.05).