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손승현,이상우,Ji-hoon Jung,Choon-Young Kim,김도훈,정신영,안병철,이재태 대한핵의학회 2015 핵의학 분자영상 Vol.49 No.4
Purpose To determine the optimal levels of thyroidstimulating hormone (TSH) levels after administration of recombinant human TSH (rhTSH) to patients with differentiated thyroid cancer (DTC), we have analyzed the clinical parameters that affected the degree of the increase in serum levels of TSH. Methods We retrospectively analyzed 276 patients with differentiated thyroid cancer (DTC), post-thyroidectomy and remnant ablation. Pearson’s correlation coefficient test was used to evaluate the correlation between serum levels of TSH after rhTSH stimulation and various clinical factors, including age, sex, height, weight, body mass index (BMI), body surface area (BSA), serum blood urea nitrogen, creatinine, and estimated glomerular filtration rate (GFR). Linear regression analysis was used to determine the predictors of the degree of increase in serum TSH level after rhTSH stimulation. Results After the rhTSH injections, all subjects achieved TSH levels of >30 μU/mL, with a mean of 203.8±83.4 μU/mL. On univariate analysis, age (r=0.255) and serum creatinine (r= 0.169) level were positive predictors for higher levels of serum TSH after rhTSH stimulation, while weight (r=–0.239), BMI (r=–0.223), BSA (r=–0.217), and estimated GFR (r=– 0.199) were negative predictors. Multiple linear regression analysis revealed that serum creatinine was the most powerful independent predictor for serum levels of TSH, followed by age, BSA, and BMI. Conclusions An increment in serum TSH after rhTSH stimulation was significantly affected by age, BSA, BMI, and creatinine, with creatinine being the most powerful predictor. By understanding the difference in the increased levels of TSH in various subjects, their dose of rhTSH can be adjusted during scheduling for radioiodine ablation, or during follow-up (recurrence surveillance) after surgery and ablation.
읽기장애위험군 학생들의 교육을 위한 중재반응모델(RTI) 적용 가능성 탐색: 어휘중재 적용 효과 분석을 바탕으로
손승현,강옥려,김소희,양민화 한국학습장애학회 2016 학습장애연구 Vol.13 No.1
본 연구는 초등학교 읽기장애위험군 학생들에게 RTI를 적용한 어휘중재의 효과를 알아보기 위한 것이다. 4주간 Tier 1에서 2개 학교 98명 학생에게 CBM 어휘력 평가를 실시하고, 검사 결과 하위 30%에 해당하는 학생들 16명을 읽기장애위험군 학생으로 선별하여 Tier 2 어휘중재를 6주간 시행하였다. 어휘중재교수를 하기 위해 2학년 국어 교과서에서 중요단어를 선정하였고, 선정한 단어를 1주일에 2회기 동안 어휘의 정의를 명시적으로 가르치고 어휘가 사용된 문장을 만드는 등의 활동을 직접교수의 단계에 따라 하였다. Tier 1과 Tier 2 중재를 시행하는 동안 모든 학생들을 대상으로 측정한 CBM 어휘력 평가 결과를 분석하여 어휘중재의 효과를 보고하였다. 연구의 결과 Tier 2중재를 받은 읽기장애위험군 학생들이 통제집단 학생들보다 통계적으로 높은 어휘성취를 보여주었다. 연구의 결과를 바탕으로 본 연구의 제한점과 추후 연구에 대한 제안점을 논의하였다. The purpose of current study was to examine the effects of tiered vocabulary intervention for students who are at-risk for reading failure. Students who received Tier 2 intervention were those whose scores were below 30 percentile on CBM vocabulary tests during 4-week Tier 1 intervention. Sixteen at-risk students received Tier 2 intervention involving two classrooms across two schools. Another 16 at-risk students received the general language art instruction(Tier 1 intervention) composing the control group. The Tier 2 intervention was implemented for six weeks. Vocabulary intervention was implemented using direct instruction for experimental group students, targeting vocabularies selected from Korean textbook about definitions and sentences using target words. Findings from this study reported the results from CBM vocabulary tests to examine the effects of Tier 2 intervention. Results indicated that students who received Tier 2 intervention made significantly higher achievement on CBM vocabulary tests than the students in the control group. Limitations and future research suggestions were discussed based on the results of the study.
기록사진을 통한 ‘탈식민 온라인사진전’ 구축하기 - ‘70년만의 귀향’ 온라인 전시구성을 중심으로-
손승현 한국사진학회 2023 AURA Vol.- No.51
This study is about the process of establishing an online photo exhibition platform for documentary photographs of the remains and return of victims of forced labor in Hokkaido during the Japanese colonial period with the participation of Korean and Japanese citizens in the context of the times in East Asia. In addition, through this, the method of delivering messages in records through exhibition composition was studied from an visual anthropology perspective amid the characteristics and limitations of the medium called photography. The photos that triggered the exhibition were taken directly on the spot as researchers participated in the "Joint Workshop in East Asia," a civic group between Korea and Japan that carried out the discovery and return of victims of forced labor. Based on these recorded photos, the online photo exhibition was intended to be built as an "online virtual space photo exhibition" containing a "decolonial perspective." Starting with the study of the online exhibition composition process of "70 years homecoming." it is hoped that meaningful discussions will continue on the use of documentary photos in East Asia's history research and the possibility of new values and spectra.
생체 in-vivo 측정용 실리콘 압저항형 압력센서의 제조와 그 특성
손승현,최시영,배혜진 한국센서학회 2001 센서학회지 Vol.10 No.3
A pressure sensor on the tip of a catheter which is utilized to measure the in-vivo pressure in a human body was fabricated and the characteristic of the pressure sensor was measured. To fit into a catheter with 1 mm caliber, samples of 150 ㎛(thickness) x (600, 700, 800, 900, 1000) ㎛(width) x 2 mm(length) was fabricated. The thicker face with 450 ㎛ thickness of SDB wafer was made thin to 134 ㎛ thickness using KOH etchant and it made possible to fabricate sensor cell with the width shorter than 1 mm. Different to the whitstone bridge sensor, we formed one piezoresistor and one reference resistor in sensor. Therefore there are possibilities of reduction of the sensitivity, then by using the simulation tool ANSYS 5.5.1, the location and the type of the piezoresistor was optimized. Another piezoresistar type of sensor which contain one longitudinal and one transverse piezoresistor was fabricated at the same time, but the sensitivity was not improved very much. To get the output versus the pressure, a constant current source and a implementation amplifier was used. As a result, the maximum sensitivity of the sensor with one piezoresistor was 1.6 ㎶/V/mmHg
가스누출 감지용 실리콘 압저항형 절대압센서의 제조 및 온도보상
손승현,김우정,최시영 ( Seung Hyun Son,Woo Jeong Kim,Sie Young Choi ) 한국센서학회 1998 센서학회지 Vol.7 No.3
Silicon piezoresistive absolute pressure sensor for gas leakage alarm system was developed. This sensor must operate normally in the range of 0∼600 mmH₂O pressure, and 100 temperature. To make the most of this sensor for gas leakage alarm system, gas must not leak from the sensor itself when the diaphragm of the sensor fractures. Thus, the sealed diaphragm cavity was anodically bonded to Pyrex 7740 glass under the condition of 10^(-4) torr at 400 ℃. The sensitivity of developed sensor was 4.06 ㎶/VmmH₂O for 600 mmH₂O full-scale pressure range. And temperature compensation method of this sensor is to change bridge-input-voltage linearly in proportion to the temperature variation by using diode(YXIN4001) or Al thin film resistor. By these methods the temperature effect in the range of 0∼100℃ was compensated over 80% for offset drift, 95% for sensitivity.