Antibiotic amoxicillin removal from aqueous solution using magnetically modified graphene nanoplatelets

O¨zge Kerkez-Kuyumcu,Sahika Sena Bayazit,Mohamed Abdel Salam 한국공업화학회 2016 Journal of Industrial and Engineering Chemistry Vol.36 No.-

The removal of antibiotic amoxicillin (AA) from aqueous solution was investigated using magneticallymodified graphene nanoplatelets (M-GNPs). M-GNPs were prepared by mixing GNPs with freshlyprepared magnetite nanopartilcles, and characterized using TEM, and XRD. The characterization resultsrevealed the homogenous distribution of the magnetite nanopartilcles over the surface of transparentplatelet-like graphene platlets. The M-GNPs proved to possess superior adsorption capacity comparedwith the pristine GNPs and the magnetite nanopartilces. The effects of different operational parameterswhich affect the removal process were explored; adsorbent amounts, contact time, initial pH,temperature, and the initial concentration of AA. The results showed the great affinity of the M-GNPstoward the AA and the maximum adsorption capacity was found to be 14.10 mg g 1. The adsorptionmechanism of AA by the M-GNPs involved p–p stacking and electrostatic interaction. The adsorptionwas studied kinetically and thermodynamically, and was found to mainly follow pseudo-second-orderkinetic model, and was spontaneous and exothermic in nature.

A Comparative Study of Hedges between ES and KS in Two Fields of Study: English Education vs. Biology

Hoe Kyeung Kim,Ö,zge Yol,Sang-Geun Lee 한국영어학학회 2020 영어학연구 Vol.26 No.1

The appropriate use of hedges in scientific fields indicates that the writer/speaker is aware of the conventions of academic writing. Korean EFL learners have been known to experience difficulties in correctly using hedging devices due to the L1 conventions of writing. Studies on their use of hedges, however, have relied mostly on a single genre or discipline. This study compared uses of hedges between Korean EFL learners (KS) and English speakers (ES) in two academic fields, English Education and Biology, to reveal how the KS group employs English hedges differently from the ES in dissertation writing. Adopting Salager-Meyer’s (1994) taxonomy, we analyzed the discussion sections of 80 doctoral dissertations, 40 by KS and 40 by ES, in two fields, showing that the KS group used hedges noticeably less than the ES, especially, in Biology. These findings imply that Korean EFL learners should fully understand the positive functions of hedges in academic writing as well as the importance of distinctive writing conventions in different disciplines. No over-generalization of conservative perception of hedging devices to the fields of science should be encouraged.

Segmenting women fashion magazine readers based on reasons of buying, fashion involvement and age: a study in the Turkish market

Oylum Korkut Altuna,O¨ zge Sig˘ irci,F. Mu¨ge Arslan 한국마케팅과학회 2013 Journal of Global Fashion Marketing Vol.4 No.3

The objective of this study is to understand why women buy fashion magazines and tocluster them accordingly. Hence fashion magazine consumers are clustered into groupsbased on why they buy fashion magazines, their fashion involvement levels, and theirages. According to the findings of the study, the reasons why women buy fashionmagazines may be defined under 13 dimensions. Moreover, three distinct clusters arefound and labeled as “Young occasional buyers interested in being informed ondifferent styles and brands”; “Elder deal-prone low-fashion-involved buyers interestedin current events and assessments on current events”; and “Settled high-fashioninvolvedregular magazine buyers interested both in trends and in content, design andvisuality of magazines.” All three clusters are distinct and thus should be subject todifferent marketing strategies. The study is significant because although fashionmagazines are one of the most important distribution channels for fashion marketing,research on them is very limited. Moreover, this research will offer insight both forfashion magazine marketers, who will be able to determine marketing strategiesaccording to the varying clusters formed, and for academicians who are interested infashion marketing.

Effects of orthodontic force on root surface damage caused by contact with temporary anchorage devices and on the repair process

Özge Çelik Güler,Sıddık Malkoç 대한치과교정학회 2019 대한치과교정학회지 Vol.49 No.2

Objective: This study aimed to evaluate the effects of force loading on root damage caused by contact with temporary anchorage devices (TADs) during orthodontic treatment and to examine the repair process 4, 8, and 12 weeks after TAD contact by micro-computed tomography (CT). Methods: We enrolled 42 volunteers who required bilateral upper first premolar extractions. The experimental study design was as follows. For both first premolars, cantilever springs were placed, and then TADs were immediately inserted between the premolars of all volunteers. According to the removal order of the appliances, the participants were divided into the TAD group (Group T: n = 21, only TAD removal) and the spring group (Group S: n = 21, only spring removal). A splitmouth design was adopted in both groups as follows. For each volunteer, the left premolars were extracted 4, 8, or 12 weeks after TAD–root contact. The right premolars were extracted immediately after contact in both groups (Groups T-C and S-C) and used as positive controls. Resorption volumes and numbers of craters were determined by micro-CT. Results: The numbers of resorption craters were higher in Group T than in Group S at 8 and 12 weeks (p < 0.01). Crater volumes were higher in Group T than in Group S at 4 and 12 weeks (p < 0.01, both). Conclusions: Root injury was not completely repaired 12 weeks after root–TAD contact, even when the TADs were removed in cases of continuous force application.

Applying nano-HA in addition to scaling and root planing increases clinical attachment gain

Özge Uysal,Gülbahar Ustaoğlu,Mustafa Behçet,Önder Albayrak,Mustafa Tunalı 대한치주과학회 2022 Journal of Periodontal & Implant Science Vol.52 No.2

Purpose: This study evaluated the efficacy of treating periodontitis using subgingival nanohydroxyapatite powder with an air abrasion device (NHAPA) combined with scaling and root planing (SRP). Methods: A total of 28 patients with stage III periodontitis (grade B) were included in this study, although 1 was lost during follow-up and 3 used antibiotics. The patients were divided into a test group and a control group. All patients first received whole-mouth SRP using hand instruments, and a split-mouth approach was used for the second treatment. In the test group, the teeth were treated with NHAPA for 15 seconds at 70% power per pocket. Subgingival plaque samples were obtained from the 2 deepest pockets at the test and control sites before treatment (baseline) and 3 months after treatment. The full-mouth plaque index (PI), gingival index (GI), papillary bleeding index (PBI), bleeding on probing (BOP), probing depth (PD) and clinical attachment level (CAL) were recorded at baseline and at 1- and 3-month post-treatment. Real-time polymerase chain reaction was used to determine the colonisation of Treponema denticola (Td), Porphyromonas gingivalis (Pg), and Aggregatibacter actinomycetemcomitans in the subgingival plaque. Results: From baseline to the first month, the test group showed significantly larger changes in BOP and CAL (43.705%±27.495% and 1.160±0.747 mm, respectively) than the control group (36.311%±27.599% and 0.947±0.635 mm, respectively). Periodontal parameters had improved in both groups at 3 months. The reductions of PI, GI, BOP, PD, and CAL in the test group at 3 months were greater and statistically significant. The total bacterial count and Td and Pg species had decreased significantly by the third month in both groups (P<0.05). Conclusions: Applying NHAPA in addition to SRP improves clinical periodontal parameters more than SRP alone. Subgingival NHAPA may encourage clot adhesion to tooth surfaces by increasing surface wettability.

The Relationship between Quality of Life and Cognitive Functions, Anxiety and Depression among Hospitalized Elderly Patients

Özge Saraçlı,Ayşe Semra Demir Akca,Nuray Atasoy,Özde Önder,Ömer Şenormanc,İsmet Kaygisız,Levent Atik 대한정신약물학회 2015 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.13 No.2

Objective: Older people seek not only a longer life, but also a better quality of life (QOL). Our aim was to find out the relationship between QOL and socio-demographic factors, social activities, cognitive status, depression and anxiety symptoms among medically ill and hospitalized elderly people in Turkey. Methods: Two hundred forty three patients age 65 years or older were examined. The Socio-demographic Data Survey, the Mini Mental State Examination (MMSE), the Geriatric Depression Scale-short form (GDS-15), the Beck Anxiety Inventory (BAI) and the World Health Organization Quality of Life Instrument-Older Adults Module (WHOQOL-OLD) were applied to participants. The independent samples t-test and analysis of variance (ANOVA) were used to analyze quantitative data. Pearson’s correlation and linear regression analysis were performed. Results: The total score for QOL was significantly higher for those who saw their family members and relatives frequently rather than rarely (p=0.002), who were always busy with social activities rather than rarely or never (p<0.001), who had more years of education (p=0.003), and who were frequently exercising (p=0.023). According to linear regression analysis, the WHOQOL-OLD total score increased by 0.295 and −0.936 units, while MMSE and GDS-15 scale scores increased one unit respectively (β=0.295, t=1.979, p=0.04; β=−0.936, t=−4.881, p<0.001). Conclusion: Cognitive disabilities, depression, and other psychiatric problems along with medical disease negatively affect the QOL of elderly patients. While performing medical assessment regarding elders, detecting and treating cognitive disabilities and depression is very valuable in improving the QOL of elderly patients.

Vibration response of rotating carbon nanotube reinforced composites in thermal environment

Özge Özdemir,Iİsmail Esen,Hüseyin Ural 국제구조공학회 2023 Steel and Composite Structures, An International J Vol.47 No.1

This paper deals with the free vibration behavior of rotating composite beams reinforced with carbon nanotubes (CNTs) under uniform thermal loads. The temperature-dependent beam material is assumed to be a mixture of single-walled carbon nanotubes (SWCNTs) in an isotropic matrix and five different functionally graded (FG) distributions of CNTs are considered according to the variation along the thickness, namely the UD-uniform, FG-O, FG-V, FG-Λ and FG-X distributions where FG-V and FG-Λ are unsymmetrical patterns. Considering the Timoshenko beam theory (TBT), a new finite element formulation of functionally graded carbon nanotube reinforced composite (FGCNTRC) beam is created for the first time. And the effects of several essential parameters including rotational speed, hub radius, effective material properties, slenderness ratio, boundary conditions, thermal force and moments due to temperature variation are considered in the formulation. By implementing different boundary conditions, some new results of both symmetric and non-symmetrical distribution patterns are presented in tables and figures to be used as benchmark for further validation. In addition, as an alternative advanced composite application for rotating systems exposed to thermal load, the positive effects of CNT addition in improving the dynamic performance of the system have been observed and the results are presented in several tables and figures.

CRISPR/Cas systems and anti-repeat sequences of Lactobacillus curvatus, Lactobacillus graminis, Lactobacillus fuchuensis, and Lactobacillus sakei genomes

Ilıkkan Özge Kahraman 한국미생물학회 2021 미생물학회지 Vol.57 No.1

CRISPR/Cas system (Clustered regularly interspaced short palindromic repeats–CRISPR associated genes) helps the bacteria or the archaea to gain immunity against phage or plasmid invasions. Lactobacillus curvatus has been known to be phylogenetically related to Lactobacillus fuchuensis, Lactobacillus graminis, and Lactobacillus sakei. In this study, this relationship has been investigated in terms of CRISPR/Cas systems, Cas1, Cas2 amino acid sequences, protospacers, and anti-repeat sequences. A total of 54 genomes (34 whole-genome and 20 draft genome) were investigated, 25 genomes had CRISPR/Cas system, namely, 23 type II-A, 2 II-C, and 2 I-E. The pairwise identity of anti-repeat sequences was 77.4%. Phylogeny analysis and alignment of Cas1 and Cas2 amino acid sequences were carried out to evaluate the relationship among CRISPR subtypes and four species. The phylogenetic tree tended to split into branches corresponding to the CRISPR/Cas subtype II-A, II-C, and I-E. According to protospacer analysis, common invaders of strains were Pediococcus damnosus, Pediococcus claussenii, Lactobacillus brevis, Lactobacillus backii, Lactobacillus plantarum, and Lactobacillus sakei. The secondary structure of seven different repeat sequences was depicted. Recently, although detection of CRISPR/Cas systems has been highly attractive for genotyping, this intention has also been used for endogenous genome editing to improve the industrial benefits of lactic acid bacteria. This detailed study will provide a perspective on these approaches.

Potentially Inappropriate Medication Use among Nursing Home Residents: Medication Errors Associated with Pro re nata Medications and the Importance of Pill Burden

Fatma Özge Kayhan Koçak,Emin Taşkıran,Zehra Kosuva Öztürk,Sevnaz Şahin 대한노인병학회 2022 Annals of geriatric medicine and research Vol.26 No.3

Background: The use of potentially inappropriate medications (PIM) has become more common among nursing home residents (NHR). This study focused on drugs initially prescribed as pro re nata (PRN) medications and pill burden in association with PIM among NHR. Methods: This observational cross-sectional study was conducted between March and April 2019 on 225 adult NHR aged ≥60 years. Results: The prevalence of PIM was 47.6% among NHR according to the Screening Tool of Older Persons' Prescriptions (STOPP) criteria version 2. The most frequent PIM was the use of any drug prescribed without evidence-based clinical indication; most medication errors were associated with PRN medications. The prevalence rates of PRN in non-PIM and PIM users were 12% and 62.4%, respectively. PRN medications that most commonly caused PIM were non-steroidal anti-inflammatory drugs and proton pump inhibitors. The cut-off value for both medications and pills to correctly identify participants with PIM was 5.5. Pill burden had a similar sensitivity to polypharmacy in identifying individuals with PIM. Conclusion: Medication errors associated with PRN medications were overlooked as factors that increased the risk of PIMs. The most common error related to PRN medications was the continued daily use despite symptom resolution.

Predictability of Metabolic Syndrome Diagnosed by Body Mass Index for Cardiovascular Risk in Older Patients Treated with Levothyroxine

Fatma Özge Kayhan Koçak,Sumru Savas,Zeliha Fulden Saraç 대한노인병학회 2022 Annals of geriatric medicine and research Vol.26 No.2

Background: We investigated the prevalence and metabolic features of two definitions of metabolic syndrome (MS) between older patients with chronic thyroiditis treated with levothyroxine (LT4) and controls. We also assessed the ability of both criteria to predict cardiovascular (CV) risk. Methods: This cross-sectional, retrospective study included individuals aged ≥60 years who attended a geriatric outpatient clinic between January 2015 and December 2018. The LT4 treatment group was classified as having high or low CV risk based on the Framingham score. Results: This study enrolled 111 patients with chronic thyroiditis treated with LT4 and 131 patients without thyroid disease as the control group. The prevalence of MS according to the World Health Organization (WHO) criteria and American Association of Clinical (AACE) criteria was similar in the LT4 treatment (21.6% and 26.1%, respectively) and the control (30.5% and 34.4%, respectively) groups (p>0.05). While the prevalence of MS and CV risk did not differ significantly between the control and LT4 treatment groups, the prevalence of MS with both definitions was higher among individuals with high CV risk in the LT4 treatment group (p<0.05). For the prediction of CV risk, the sensitivity and specificity of the AACE criteria were higher than those of the WHO criteria in the LT4 treatment group. Conclusions: The prevalence of MS in euthyroid patients treated with LT4 was similar to that of patients without thyroid disease. When the LT4 treatment group was classified based on CV risk, MS was more common in those with a high CV risk.