Determination of the Effect of Different Ground Mustard Seeds on Quality Characteristics of Meatballs

Muhammed Yusuf ?a?lar,Veli G?k,Oktay Tomar,G?khan Akarca 한국축산식품학회 2018 한국축산식품학회지 Vol.38 No.3

This study investigated the effect of yellow, black, and brown mustard seeds on color, lipid oxidation (thiobarbituric acid-reactive substances [TBARS]), and microbiological and sensory qualities of meatballs during storage. Heat treatment of mustard seeds affected the TBARS value of meatball samples (p<0.0001). The addition of mustard seeds decreased TBARS value of meatball samples (p<0.0001). Heat treatment of mustard seeds decreased the L*, a* and b* values of meatball samples (p<0.0001). The meatball samples with mustard seeds increased b* value of meatball samples however it decreased a* value of meatball samples (p<0.0001). The addition of mustard seeds decreased aerobic mesophilic bacteria count (p<0.0001), Enterobacteriaceae count (p<0.0001), psychrophilic bacteria count (p<0.0001) and yeast and mold count of meatball samples (p<0.0001). On a given storage day, the yellow mustard added meatballs sample was given higher color, appearance, flavor, acceptability ratings than those added black and brown mustard. Regarding sensory and microbiological properties, mustard seed contributed to microbiological quality and sensorial properties of meatball samples.

Two-Phase Interleaved Buck Converter with a new Digital Self-Oscillating Modulator

Lars T. Jakobsen,Michael A. E. Andersen 전력전자학회 2007 ICPE(ISPE)논문집 Vol.- No.-

This paper presents a new Digital Self-Oscillating Modulator (DiSOM) for DC/DC converters. The DiSOM modulator alllows the digital control algorithm to sample the output voltage at a sampling frequency higher than the converter switching frequency. This enables higher control loop bandwidth than for traditional digital PWM modulators given a certain switching frequency. A synchronised version of the DiSOM modulator is derived for interleaved converters. A prototype interleaved Buck converter for Point of Load applications has been designed and built to test the performance of DiSOM modulator. The DiSOM modulator and a digital control algorithm have been implemented in an FPGA. Experimental results show that the converter has a very fast transient response when a loadstep is applied to the output. For a loadstep of 50% of nominal output current the output voltage overshoot is less than 2.5% of the nominal output voltage and the settling time is just 8 switching periods.

A gravimetric method to determine horizontal stress field due to flow in the mantle in Fennoscandia

Nureldin A.A. Gido,Mohammad Bagherbandi,Lars E. Sjöberg 한국지질과학협의회 2019 Geosciences Journal Vol.23 No.3

Mass changes and flow in the Earth’s mantle causes the Earth’s crust not only to move vertically, but also horizontally and to tilt, and produce a major stress in the lithosphere. Here we use a gravimetric approach to model sub-lithosphere horizontal stress in the Earth’s mantle and its temporal changes caused by geodynamical movements like mantle convection in Fennoscandia. The flow in the mantle is inferred from tectonics and convection currents carrying heat from the interior of the Earth to the crust. The result is useful in studying how changes of the stress influence the stability of crust. The outcome of this study is an alternative approach to studying the stress and its change using forward modelling and the Earth’s viscoelastic models. We show that the determined horizontal stress using a gravimetric method is consistent with tectonics and seismic activities. In addition, the secular rate of change of the horizontal stress, which is within 95 kPa/year, is larger outside the uplift dome than inside.

Concordance of Endoscopic Ultrasonography-Guided Fine Needle Aspiration Diagnosis with the Final Diagnosis in Subepithelial Lesions

Erkan Çağlar,İbrahim Hatemi,Deniz Atasoy,Gürhan Şişman,Hakan Şentürk 대한소화기내시경학회 2013 Clinical Endoscopy Vol.46 No.4

Background/Aims: In this study we aimed to determine the rate of concordance of endoscopic ultrasonography (EUS)-guided fine needle aspiration (FNA) diagnosis with the final diagnosis obtained by surgery or endoscopic resection and follow-up in upper gastrointestinal subepithelial lesions. Methods: We retrospectively studied patients with subepithelial lesions who underwent EUS at our center from 2007 to 2011. Results: We had a final diagnosis in 67 patients (mean age±SD, 51.23±12.48 years, 34.3% [23] female, 65.6% [44] male). EUS-FNA was performed in all of the patients. On-site pathology was not performed. In nine of the patients, the obtained material which was obtained was insufficient. The cytologic examination was benign in 31 and malignant in 27 of the patients. Based on the final diagnosis, the EUS-FNA had a sensitivity of 96%, a specificity of 100%, and a diagnostic yield of 85%. Conclusions: The diagnostic yield of EUS-FNA, in the absence of the on-site cytopathologist, is feasible for the diagnosis of subepithelial lesions of the upper gastrointestinal system.

The Effect of Tonsillectomy and Adenoidectomy on Right Ventricle Function and Pulmonary Artery Pressure by Using Doppler Echocardiography in Children

Onur Çağlar Acar,Abdurrahman Üner,Mehmet Fatih Garça,İbrahim Ece,Serdar Epçaçan,Mahfuz Turan,Ferhat Kalkan 대한이비인후과학회 2016 Clinical and Experimental Otorhinolaryngology Vol.9 No.2

Objectives. The purpose of the present study is to emphasize the efficacy of the myocardial performance index and tricuspid annular plane systolic excursion (TAPSE) in the determination of impaired cardiac functions and recovery period following the treatment in children with adenoid and/or tonsillar hypertrophy. Methods. Fifty-three healthy children after routine laboratory, imaging and clinical examinations, with adenoid and/or tonsillar hypertrophy were evaluated before and 3 months after adenotonsillectomy for cardiac functions using M mode and Doppler echocardiography. Results. The mean age of cases was 6.4±3.0 years, 34 (65%) were male, and 19 (35%) were female. Pulmonary hypertension was observed to be mild in 3 patients and moderate in 1 patient preoperatively. When the preoperative and postoperative echocardiographic measurements of the patients were compared, the tricuspid valve E wave velocity, the E/A ratio (E, early diastolic flow rate; A, late diastolic flow rate), and the TAPSE values were determined to be significantly higher postoperatively (P<0.05). The tricuspid valve deceleration time, the isovolumetric relaxation time and the systolic pulmonary artery pressure were found to be significantly lower compared to the preoperative values (P<0.05). Conclusion. Adenoidectomy and/or tonsillectomy may prevent cardiac dysfunctions that can develop in the later periods due to adenoid and/or tonsil hypertrophy in children, before the appearance of the clinical findings of cardiac failure.

Expression analyses of human cleft palate tissue suggest a role for osteopontin and immune related factors in palatal development

Linda P. Jakobsen,Rehannah Borup,Janni Vestergaard,Lars A. Larsen,Kasper Lage,Lisa Leth Maroun,Inger Kjaer,Carsten U. Niemann,Mikael Andersen,Mary A. Knudsen,Kjeld Møllgård,Niels Tommerup 생화학분자생물학회 2009 Experimental and molecular medicine Vol.41 No.2

Cleft lip and/or palate (CL/P) is a common congenital malformation with a complex etiology which is not fully elucidated yet. Epidemiological studies point to different etiologies in the cleft lip and palate subgroups, isolated cleft lip (CL), isolated cleft palate (CP) and combined cleft lip and palate (CLP). In order to understand the biological basis in these cleft lip and palate subgroups better we studied the expression profiles in human tissue from patients with CL/P. In each of the CL/P subgroups, samples were obtained from three patients and gene expression analysis was performed. Moreover, selected differentially expressed genes were analyzed by quantitative RT-PCR, and by immunohistochemical staining of craniofacial tissue from human embryos. Osteopontin (SPP1) and other immune related genes were significantly higher expressed in palate tissue from patients with CLP compared to CP and immunostaining in palatal shelves against SPP1, chemokine receptor 4 (CXCR4) and serglycin (PRG1) in human embryonic craniofacial tissue were positive, supporting a role for these genes in palatal development. However, gene expression profiles are subject to variations during growth and therefore we recommend that future gene expression in CL/P studies should use tissue from the correct embryonic time and place if possible, to overcome the biases in the presented study. Cleft lip and/or palate (CL/P) is a common congenital malformation with a complex etiology which is not fully elucidated yet. Epidemiological studies point to different etiologies in the cleft lip and palate subgroups, isolated cleft lip (CL), isolated cleft palate (CP) and combined cleft lip and palate (CLP). In order to understand the biological basis in these cleft lip and palate subgroups better we studied the expression profiles in human tissue from patients with CL/P. In each of the CL/P subgroups, samples were obtained from three patients and gene expression analysis was performed. Moreover, selected differentially expressed genes were analyzed by quantitative RT-PCR, and by immunohistochemical staining of craniofacial tissue from human embryos. Osteopontin (SPP1) and other immune related genes were significantly higher expressed in palate tissue from patients with CLP compared to CP and immunostaining in palatal shelves against SPP1, chemokine receptor 4 (CXCR4) and serglycin (PRG1) in human embryonic craniofacial tissue were positive, supporting a role for these genes in palatal development. However, gene expression profiles are subject to variations during growth and therefore we recommend that future gene expression in CL/P studies should use tissue from the correct embryonic time and place if possible, to overcome the biases in the presented study.

스웨덴의 에너지와 환경

Bern Lars A. 한국에너지협의회 1989 에너지協議會報 Vol.10 No.-

An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

Liu, Jianfang,Lichtenberg, Tara,Hoadley, Katherine A.,Poisson, Laila M.,Lazar, Alexander J.,Cherniack, Andrew D.,Kovatich, Albert J.,Benz, Christopher C.,Levine, Douglas A.,Lee, Adrian V.,Omberg, Lars Elsevier 2018 Cell Vol.173 No.2

<P><B>Summary</B></P> <P>For a decade, The Cancer Genome Atlas (TCGA) program collected clinicopathologic annotation data along with multi-platform molecular profiles of more than 11,000 human tumors across 33 different cancer types. TCGA clinical data contain key features representing the democratized nature of the data collection process. To ensure proper use of this large clinical dataset associated with genomic features, we developed a standardized dataset named the TCGA Pan-Cancer Clinical Data Resource (TCGA-CDR), which includes four major clinical outcome endpoints. In addition to detailing major challenges and statistical limitations encountered during the effort of integrating the acquired clinical data, we present a summary that includes endpoint usage recommendations for each cancer type. These TCGA-CDR findings appear to be consistent with cancer genomics studies independent of the TCGA effort and provide opportunities for investigating cancer biology using clinical correlates at an unprecedented scale.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Generation of TCGA Clinical Data Resource for 11,160 patients over 33 cancer types </LI> <LI> Analysis of clinical outcome endpoints with usage recommendations for each cancer </LI> <LI> Demonstration of data validity and utility for large-scale translational research </LI> </UL> </P> <P><B>Graphical Abstract</B></P> <P>[DISPLAY OMISSION]</P>

Effectiveness of active video games in overweight and obese adolescents: a systematic review and meta-analysis of randomized controlled trials

Erçelik Zübeyde Ezgi,Çağlar Seda 대한소아내분비학회 2022 Apem Vol.27 No.2

Purpose: The purpose of this review was to assess the effect of active video games among overweight and obese adolescents.Methods: A systematic review and meta-analysis were conducted using records from the English-language electronic databases MEDLINE, the Web of Science, and PubMed. These databases were searched from January 2010 to December 2020 using the keywords (adolescent*) AND (overweight OR obese *) AND (active video games OR exergaming * OR video game*).Results: Five articles met the inclusion criteria. Four studies were conducted in the United States of America and 1 study was conducted in Canada. In addition, all included articles had a randomized controlled trial study design. It was determined that the sample size of the studies was 30–46 participants and there were a total of 195 overweight and obese adolescents across the included studies. Active video gaming was negatively associated with changes in body mass index percentile (mean difference [MD], -1.77; 95% confidence interval [CI], -2.55 to -0.99; p<0.001) and total cholesterol (MD, -11.16; 95% CI, -16.64 to -5.68; p<0.001).Conclusion: Playing active video games can reduce both the body mass index percentile and total cholesterol in overweight and obese adolescents. Active video games can provide a different method for combating childhood obesity. High-quality randomized controlled trials are recommended to assess the impact of game-based interventions.

An investigation of reaction progression through the catalyst bed inmethanol autothermal reformation

김형만,최갑승,윤형철,J. Lars Dorr,Paul A. Erickson 대한기계학회 2008 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.22 No.2

This study investigates autothermal reforming of fuel cell-grade methanol as a method for producing hydrogen for transportation applications. A previous study on the effects of oxygen-to-carbon ratio on ATR reactor performance showed that the optimum of O2/CH3OH=0.30 found in the experimental tests is 30% higher than the theoretical optimum of 0.23. In this study, the influence of catalyst bed length is investigated to give insight into the reaction progression through the catalyst bed in methanol autothermal reformation. The effect of reaction progression through the catalyst bed is experimentally investigated in relation to reactor output parameters of fuel conversion, temperature profile, and reactor efficiency. The results from this study serve as a baseline for future research of autothermal reforming of hydrocarbon fuels as a method for producing hydrogen.