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      • 한의진단명과 진단요건의 표준화 연구 III : 3차년도 연구결과 보고

        최선미,양기상,최승훈,박경모,박종현,심범상,김성우,노석선,이인선,정진홍,이진용,김달래,임형호,김윤범,박성식,송태원,김종우,이승기,최윤정,신순식 한국한의학연구원 1997 한국한의학연구원논문집 Vol.3 No.1

        The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the third year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows : - analyzing and differentiating of epidemic febrile disease - analyzing and differentiating in accordance with the Sasang constitution medicine based on four-type recognition - differentiation of disease according to pathological changes of Chong and Ren channels - standards for diagnosis of women's disease - standards for diagnosis of children's disease - standards for diagnosis of motor and sensor disturbance (-muscle. born, joint, etc.) - standards for diagnosis of neuropsychiatric disease - standards for diagnosis of five sense organ disease - standards for diagnosis of external disease The indivisual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name, notion of diagnosis pattern, index of differentiation of symptoms and signs, the main point of diagnosis, analysis of diagnosis pattern, discrimination of diagnosis pattern, prognosis, a way of curing a disease, prescription, herbs in common use, disease appearing the diagnosis pattern, documents. The standards for diagnosis of each disease was arranged by the diagnostic requirements in the following order : another name, notion of disease, the main point of diagnosis, analyzing and differentiating of disease, analysis of disease, discrimination of disease, prognosis, a way of curing and prescription of disease, disease in western medicine appearing the disease in oriental medicine, documents.

      • KCI등재

        경도인지장애 환자에서 복합-일상활동의 제한

        홍지혜,정한용,김양래,이소영,김진만 大韓神經精神醫學會 2008 신경정신의학 Vol.47 No.4

        Objectives : Mild cognitive impairment (MCI) is distinguished from mild dementia by an absence of global intellectual deterioration and the preservation of activities of daily living (ADL). Recently, however, it became apparent that impairment of instrumental activities of daily living (IADL) is present before the threshold of dementia is reached. Thus, we want to examine whether IADL are impaired in patients with MCI, and which items of IADL are particularly involved. We divided the MCI group into amnestic (aMCI) and non-amnestic MCI (naMCI), and compared to the cognitively nonnal controls. In this study, we focused on the instrumental activities of daily living (IADL). Methods : The sample consisted of 69 community-dwelling older adults from a welfare center for the aged in Korea. The subjects were divided into three diagnostic groups; aMCI [N=19, memory domains below -1.5 standard deviation (SD)], naMCI (N= 19, other cognitive domains below -1.5 SD, except memory domains) and cognitive normal controls (N=31). Subjects were assessed both on IADL and the cognitive function. In order to assess the IADL, we used the Seoul -Instrumental Activities of Daily Living (S-IADL). Included measures of cognitive tests are as follows ; Seoul Verbal Learning Test (SVLT), Rey Complex Figure Test (RCFT), Korean-Boston Naming Test (K-BNT), Stroop test, and Korean-Mini Mental Status Examination (K-MMSE). Groups were compared on the S-IADL and the cognitive tests. Results : The three groups did not differ in the mean age, gender distribution and years of education. S-IADL were shown to be different between the groups in this study. Suects with aMCI were significantly more impaired in S-IADL in comparison to the controls [F (2,50) = 4.251, P=0.020]. And on four items ofS-IADL (shopping, transportation, medication and talking about recent events), subjects with aMCI showed higher impairment compared to the controls. However, the S-IADL did not differ between the subjects with naMCI and controls. Conclusion : In this study, impairment of S-IADL was shown in subjects with aMCI. And S-IADL ofnaMCI was not Significantly differed from aMCI and controls. The results suggest that naMCI would be distinguished from aMCI in characteristics and prognosis.

      • SCOPUSKCI등재

        The Efficacy of 0.2% Brimonidine for Preventing Intraocular Pressure Rise Following Argon Laser Trabeculoplasty

        Yang Rae Ma,Byung Hyun Lee,Kun Jin Yang,Yeoung Geol Park 대한안과학회 1999 Korean Journal of Ophthalmology Vol.13 No.2

        Brimonidine tartrate of 0.5% was identified as the most effective and safe dose for acute intraocular pressure (IOP) lowering. The efficacy of brimonidine tartrate 0.2% in preventing IOP elevation after an argon laser trabeculoplasty (ALT) was evaluated. Eighty patients were selected for a randomized, prospective study. Each patient was assigned to one of four treatment regimens: (1) brimonidine before and after ALT(B/B), (2) brimonidine before and placebo after ALT(B/P), (3) placebo before and brimonidine after ALT(P/B), (4) placebo before and after ALT(P/P). IOP elevation of 5 mmHg or greater occurred in 3.3% (2/60) of brimonidine-treated patients and in 30% (6/20) of placebo-treated patients. There was a mean decrease of IOP from baseline during the first 3 hours after ALT in all brimonidine-treated groups (7.1±3.4, 6.2±4.4, 3.5±2.9 mmHg for the B/B, B/P, P/B groups), but no change of mean IOP in the Placebo-treated group. Only one drop of brimonidine tartrate of 0.2% installed either before or after ALT was sufficient to prevent post-ALT IOP spike and minimize the undesired systemic adverse effects that two drop installation can produce.

      • Attraction Effect and Electrophysiological Response of Spearmint Oil against Lantern Fly, Lycorma delicatula

        Jin-Won Jeong,Sang-Rae Moon,Jeong-Oh Yang,Gil-Hah Kim 한국응용곤충학회 2010 한국응용곤충학회 학술대회논문집 Vol.2010 No.05

        This study was performed to investigate attraction effect of six plant essential oils and to confirm their electrophysiological response against Lycorma delicatula. Among the tested oils, spearmint oil (94.1%) significantly attracted L. delicatula at a dose of 1.25㎕/cm2 by using an olfactometer. In dose response to spearmint oil, a dose of 2.5㎕/cm2 was very effective. GC-MS analysis revealed that the active components responsible for the effective attraction effect of spearmint oil were carvone (70.6%) and limonene (54.8%). Of the two active components, carvone was more significant than limonene with reference to attraction activity against L. delicatula. Analysis by GC-EAD showed, major components of spearmint oil that elicited response in L. delicatula antennae, indicating the potential role of the essential oil as attractant that determine the choice of the attraction material. In the field test, spearmint oil exhibited attraction effect up to 5 days. This effect was different in accordance with test places and treatment dose.

      • KCI등재후보

        Factors Impacting Initial Trust and Purchase Intention in Internet Shopping Malls

        Rae-jin Yang(양래진),Hyoung-gil Kim(김형길),In-am Song(송인암),Dong-cheol Lee(이동철),Jung-kyun Kim(김정균) 한국인터넷전자상거래학회 2007 인터넷전자상거래연구 Vol.7 No.4

        인터넷 쇼핑몰에서 소비자들의 초기신뢰는 재방문이나 회원가입, 개인정보 제공, 구매행동과 같은 신뢰의 후속적인 행동과 연계되어있어 인터넷 쇼핑몰 연구의 중요한 주제로 다루어져 왔다. 특히 인터넷 쇼핑몰은 대면 접촉이 없이 인터넷상에서 업체가 보여주는 정보에만 의존해야 하며 거래를 위해서는 신용카드와 같은 자신의 개인정보를 제공해야만 하므로 오프라인 환경에서보다 신뢰가 훨씬 중요한 의미를 가진다. 본 연구는 한국과 중국의 소비자들을 대상으로 인터넷 쇼핑몰을 처음으로 방문하여 형성되는 초기신뢰의 영향요인과 구매의도에 관한 내용을 중심으로 연구하였다. 실증 분석결과 한국과 중국 소비자 모두 기업의 프로파일과 웹사이트 품질이 인터넷쇼핑몰 초기신뢰에 영향을 미치는 것으로 나타났으며, 개인적 특성에 있어서는 한국에서는 소비자의 신뢰성향이, 중국에서는 개인의 혁신성향이 초기신뢰에 영향을 미치는것으로 나타났다. 또한 한국과 중국 소비자 모두 지각된 기술적 기반이 초기신뢰에 영향을 미치는것으로 분석되었다. 이상의 연구결과를 바탕으로 하여, 인터넷 쇼핑몰 업체들의 고객의 초기신뢰를 구축하기 위한 마케팅 시사점을 제시하였다.

      • Attractants and trap development for Ussur brown katydid, Paratlanticus ussuriensis (Orthoptera: Tettigoniidae)

        Doo-Jin Noh,Jung-Oh Yang,Sang-Rae Moon,Changmann Yoon,Shin-Ho Kang,Ki-Su Ahn,Gil-Hah Kim 한국응용곤충학회 2008 한국응용곤충학회 학술대회논문집 Vol.2008 No.10

        Recently, Ussur brown katydid outbreaks caused a serious pest problem in areas of Yeongdong, Chungbuk. This study was performed to control the pest with environment-friendly method. Trap was made of PET plastic bottles that easily found near farmhouse. Attractant materials such as oak (Quercus acutissima) leaf, fruits (peach, apple, grapefruit and pear) sarcocarp or its juices, rice wine (makgeolli) and fish meal were directly applied into the manufactured trap and investigated for the attraction efficacy compared with the funnel trap. During one day, manufactured trap (fish trap) attracted the Ussur brown katydid more than funnel trap. The efficacy of attractant materials were as follows: peach juice (32.7 adults)> rice wine+fish meal (31.3 adults) > rice wine (27.0 adults) > pear juice (19.0 adults) > apple juice (17.2 adults) > fish meal (16.7 adults) > grapefruit juice (14.4 adults) > oak leaf (2.3 adults). The attractive efficacy of fruit juices to ussur brown katydid was more than fruit carcocarps, and the trap hangover 1m in height more than that on ground. The composition of rice wine and fish meal prolonged its efficacy when treated with disinfectant.

      • Seasonal Occurrence and Developmental Characteristics of Ussur Brown Katydid, Paratlanticus ussuriensis (Orthoptera: Tettigoniidae)

        Sang-Rae Moon,Doo-Jin Noh,Jeong-Oh Yang,Changmann Yoon,Ki-Su Ahn,Gil-Hah Kim 한국응용곤충학회 2009 한국응용곤충학회 학술대회논문집 Vol.2009 No.05

        This study was performed to investigate the seasonal occurrence, developmental characteristics of each nymphal stages with different temperatures (20, 25, 30℃), longevity and fecundity of ussur brown katydid, Paratlanticus ussuriensis, damaging by outbreaks in the orchard areas of Bitan-ri, Yeongdong, Chungbuk. Paratlanticus ussuriensis occurred from late-March to late-August with peak of mid-May. Newly emerged nymphs appeared from March and do damaged fruit orchards with peak of mid-May when P. ussuriensis existed as 4th and 5th nymphal stages. P. ussuriensis adult occurred from early-June to mid-Aug. with peak of mid-July. Total density of P. ussuriensis was showed highest in mid-May. P. ussuriensis goes through nymphal stages to 7th nymph, the ovipositor began exposed to outside from the 4th instar and the body weight increased heavily from this stage and the wings were observed from 6th instar. Developmental period was longer as increased the nymphal stages. Sex ratio of collected insect was showed as 0.57; females more than males. As increased the temperature, developmental period was to be short. Preoviposition was also to be short as 5.0, 4.3, and 3.4 days at 20, 25, 30℃, respectively, and fecundity increased as 69.0, 87.1, and 104.3 at 20, 25, 30℃, respectively. Longevity of male and female at 25℃ was showed the longest with 35.7, and 32.9 days and showed the shortest with 30.1 and 28.1 days at 30℃, respectively. The difference of developmental period in male and female were showed longer in female without relation of temperature. The eggs laid were frequently distributed 3 to 4 cm from soil surface, and showed the behavior laying eggs intensively when early oviposition period.

      • Optimization of EasyBac systemfor high-throughput expression of recombinant proteins

        Jae Young Choi,Yang-Su Kim,Hee Jin Shim,Yong Wang,Jong Yul Roh,Soo Dong Woo,Byung Rae Jin,Yeon Ho Je 한국응용곤충학회 2008 한국응용곤충학회 학술대회논문집 Vol.2008 No.10

        Recently, we constructed a novel recombinant baculovirus genome, bEasyBac, enabling easy and fast generation of pure recombinant baculovirus without any purification step. In the bEasyBac, bacteriophage lambda site-specific attachment (att) sites were introduced to facilitate the generation of recombinant viral genome by in vitro transposition. Moreover, extracellular RNase gene from Bacillus amyloliquefaciens, barnase, was expressed under the control of Cotesia plutellae bracovirus (CpBV) ORF3005 early promoter to negatively select against non-recombinant background. The bEasyBac could replicate in host insect cells only when the barnase gene was replaced to gene of interest by in vitro transposition. When the bEasyBac was transposed with pDualBac-EGFP and the EGFP expression efficiency along passage was investigated, the resulting recombinant virus, EasyBac-EGFP, showed comparable level of EGFP expression efficiency with the plaque-purified recombinant virus, AcEGFP, which was constructed using bAcGOZA system, whereas, the non-purified AcEGFP showed quite reduced level of EGFP along passages. Moreover, no non-recombinant backgrounds were detected from unpurified EasyBac-EGFP stocks. Based on these results, high-throughput condition for generation of multiple recombinant viruses in a time was established. These results suggest that the bEasyBac has an effective benefit enabling for high-throughput baculovirus expression vector without purifying recombinant virus.

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