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      • SCOPUSKCI등재

        Promotional Strategies of Local Drugstores

        Kim,Seung-Mi,Lee,Sang-Yoon,Kim,Pan-Jin,Kim,Nam-Myun,Youn,Myoung-Kil 한국유통과학회 1999 유통과학연구 Vol.1 No.1

        The retail business of drugstore was introduced to Korea for the first time 10 years ago. Since Olive Young introduced a retail store in the name of drugstore in 1999 for the first time in Korea, new distribution channel combining drugstore, cosmetic products and dairy products, etc has been made. At initial stage, the new distribution channel grew up slowly because of low specialty and economic stagnation. However, the three big distribution channels, that is to say, Olive Young (CJ), Watsons (GS) and W Store (Kolon Well Care), etc, were established to produce new distribution system following large-scaled discount stores as well as convenience stores. The purpose of the study is to investigate ways making Korean style drugstore be new retail business in addition to traditional markets, department stores, E-Mart and other general super markets and to examine problems preventing the drugstore from being promoted and to find out solutions. The speciality retailers that is called a category killer attacking department stores as well as marts is expanding market quickly. New consumption trend that gives priority to wellbeing is being expanded in accordance with high level of standards of living life: The drugstore is thought to be new alternative of distribution because it keeps special products. Young ladies who are main customers of drugstores respond to the trend sensitively to have more buying power that is thought to be promising. And, consumers' desire has become concrete and special. This is because consumers want not only convenient shopping but also special shopping system that is current trend. These days, so called Multi-shop and Total shop and other special shops have been recently opened. Special multi-shop has been concentrated on fashion product and miscellaneous goods so far: Health total wellbeing shop shall be popular in accordance with wellbeing trends. Drugstores can play an important role. Drugstores were opened for the first time ten years ago. In

      • 용융 AI-10Si 합금의 산화피막강도 및 표면 미세조직에 미치는 Mg첨가의 효과에 관한 연구

        김길수,양중식,김기주,백영남 慶熙大學校 材料科學技術硏究所 1992 材料科學技術硏究論集 Vol.5 No.-

        This study was carried out to determine the strength of oxide skins of Al-10Si alloy melts and the effect of Mg addition on the morphology of oxide skins as the practical alloy for automobile piston. This has been observed by Rotational Die Movement Equipment for the temperature range from 600℃ to 720℃, the oxidation time range from 2 min. to 60 min. and the Mg weight percent(wt %) range from 1% to 5%. As the surface temperature and the surface oxide time of alloy melts increased, the crystalization of oxide layer and the creation of oxides were verified.

      • 대황황련해독탕의 사염화탄소 유발 간장해 보호효과 미치 급성독성

        김영석,정은아,장종철,양형길,김남재,조기호,배형섭,이경섭,김동현 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2002 東西醫學硏究所 論文集 Vol.2002 No.-

        ABSTRACT - This study was performed to evaluate hepatoprotective effect of daewhang-whangryunhaedok-Tang(DWT) on liver injured rats induced by CCI_4 and the acute oral toxicity of it in mice. The activities of serum transaminase(ALT/AST), alkaline phosphatase(ALP) and lactic dehydrogenase(LDH), the levels of serum total cholesterol(TC) and triglyceride(TG), change of liver enlargement, and inhibitory activities of lipid perotidation, catalase and glutathione-S-transfrease(GST) in liver microsome were determined in hepatotoxic rats induced by CCI_4. DWT was significantly reduced the serum ALT, AST, ALP, LDH. TC and TG lecels. And, the increase of lipid peroxidation, decrease of catalase and GST activities in the liver microsome of CCI_4-intoxicated rat were significantly improved by the treatment of DWT. Male and female mice were administered maximum dosages of 5.000 mg/kg b.w. of DWT. After single oral administration of DWT to mice, we observed them daily for 2 weeks.DWT did not induce any toxic signs in the mortalitie, clinical signs, body weight changes, and gross necropsy finfings of mice. Based in these results. It is concluded that DWT may have the hepatoprotective effect on CCI_4 induced hepatotoxicity in rats. Also. DWT may have no side effect and its LD_50 value may be over 5.000mg/kg b.w. in mice.

      • KCI등재

        스모그 챔버에서 수분 반응에 의한 대기 에어로졸의 생성 및 성장

        김민철,배귀남,문길주,박주연 한국대기환경학회 2004 한국대기환경학회지 Vol.20 No.2

        Aerosol formation and growth by water vapor reactions were investigated in a 2.5-㎥ indoor smog chamber filled with the unfiltered ambient air. The relative humidity of test ambient air was elevated at 59~64% or 84~88% by adding water vapor. The aerosol number size distribution and the concentrations of O₃, NO, NO₂, and SO₂ were measured during the experiments. The O₃, and NO₂ gases were well reacted with the water vapor at high relative humidity of 84~88%, and the reaction rates of these gases seemed to be decreased at low relative humidity of 59~64%. The formation and condensational growth phenomena of ambient aerosols by water vapor reactions were observed in a Teflon bag, depending strongly on the initial particle size distribution. The water vapor reactions might be affected by the contents of oxidants produced by photochemical reactions under sunlight.

      • 고콜레스테롤 식이에 있어 제주산 해조 식이섬유 섭취에 따른 지질대사 및 항산화효소에 미치는 영향

        김길남,전유진 제주대학교 해양과환경연구소 2004 해양과환경연구소 연구논문집 Vol.28 No.2

        본 연구는 고콜레스테롤 식이 군에 제주산 해조 식이섬유의 첨가 수준을 달리한 식이가 흰쥐의 지방대사에 미치는 영향을 알아보고자 하였다. 체중이 132.3±7.34 g인 Sparague-Dawley종 수컷 흰쥐에게 고콜레스테롤혈증을 유발시키기 위하여 콜레스테롤를 식이 사료의 0.5%가 되도록 첨가하고 제주산 해조 식이섬유 분말은 식이 사료의 각각 1.0% 및 2.5%가 되도록 첨가하여 총 3군으로 나누어 4주간 사육하였다. 체중 증가량과 식이효율은 식이에 의한 영향은 없었다. 혈중 중성지방, 총콜레스테롤, LDL-콜레스테롤은 고콜레스테롤 식이에 비해 제주산 해조 식이섬유를 첨가한 군이 크게 감소하였으며 유의적 차이를 나타냈다. HDL-콜레스테롤은 고콜레스테롤 식이 쥐에 비해 제주산 해조 식이섬유를 첨가한 군이 증가하는 경향을 보였으나 유의적인 차이를 보이지 않았다. 총 콜레스테롤 함량에 대한 HDL-를레스테롤 함량의 비는 제주산 해조 식이섬유를 첨가하였을 때 유의적인 차이를 보이며 증가하였다. GPT, GOT활성의 경우 GPT활성은 군간에 비슷한 경향을 보였으며, GOT활성은 제주산 해조 식이섬유를 첨가한 군이 유의적인 차이를 보이며 감소하였다. 항산화효소인 SOD 및 catalase 활성은 식이에 의한 영향은 없었다. 이상의 결과를 볼 때 제주산 해조 식이섬유의 체내 지방대사에 있어 총 콜레스테롤과 LDL-콜레스테롤, 중성지방 및 GOT 활성을 낮추고 HDL-콜레스테롤/총 콜레스테롤 비는 높이는 효과를 나타냈다. 따라서 제주산 해조 식이섬유는 생체내 항고클레스테롤 및 고콜레스테롤에 의한 스트레스로부터 간을 보호하는 것을 알 수 있었다. This study was conducted to investigate hypocholesterolemia effect of dietary fiber from seaweed in Jeju in rats supplemented with hish cholesterol diet. Seaweed dietary fiber was produced by water extraction of the mixed main red algae including Gracilaria verrucosa, Gelidium amansii, Gigartina tenella, Gloiopeltis furcata and Campylaephora hypnaeoides. Thirty male Sprague Dawley rats weighing 132.3±7.34 were divide into high cholesterol diet and high cholesterol diet plus seaweed dietary fiber 1.0% or 2.5% for 4 weeks. Dietary fiber supplement could significantly decreased serum total cholesterol (TC), triacylglyceride (TG), LDL-cholesterol (LDL-C) and GOT than in high cholesterol diet. HDL-cholesterol level and HDL-cholesterol/total cholesterol ratio in the two groups of seaweed dietary fiber supplement significantly increased comparing to those in high cholesterol diet without dietary fiber. These results suggest that the seaweed dietary fiber may reduce elevated levels of serum cholesterol concentrations.

      • 대황황련해독탕의 항고지혈증 작용

        김영석,정은아,장종철,양형길,김남재,조기호,배형섭,이경섭,김동현 경희대학교 동서의학연구소 2001 東西醫學硏究所 論文集 Vol.2001 No.-

        Whangryunhaedok-Tang (WT) is formulated with Coptidis Rhizoma, Phellodendri Cortex, Scutellariae Radix and Gardeniae Fructus, and Daewhang-whangryunhaedok-Tang (DWT) is made by the combination of Rhei Rhizoma, a wellknown anticostipation drug in WT. Therefore, DWT has been evaluated for antihyperlipidemic effects on experimental hyperlipidemic rats and mice induced by corn oil and high cholesterol-diet. Oral administration of DWT significantly inhibited the increase of serum triglyceride and LDL-cholesterol levels, and the decrease of serum HDL-cholesterol levels in hyperlipidemic rats induced by corn oil. Also, oral administration of DWT significantly prevented the increase of serum total cholesterol, triglyceride and LDL-cholesterol, and liver total cholesterol and triglyceride in 1% cholesterol-diet fed mice. These results suggest that DWT is effective for the treatment of hyperlipidemia.

      • KCI등재

        실내 스모그 챔버의 설계 및 성능평가

        배귀남,김민철,이승복,송기범,진현철,문길주 한국대기환경학회 2003 한국대기환경학회지 Vol.19 No.4

        A multi-functional indoor smog chamber was designed and evaluated lo investigate photochenical or water vapor reaction mechanisms of air pollutants. Various smog chamber experiments could be conducted using ambient air or purified air in this smog chamber. The smog chamber consisted of a housing, a Teflon bag, blacklights, injection ports, sampling ports, and utility facilities. The characteristics of light source, the wall losses of air pollutants, and the quality of purified air were experimentally investigated. The maximum NO₂ photolysis rate was 1.10min^(-1). In a 2.5-m³ Teflon bag, the wall losses of ambient O₃, NO, and NO₂were 1.2~2.4×10^(-3)min^(-1), 0.7~2.0×10^(-3)min^(-1), and 0.4-2.0×10^(-3)min^(-1), respectively. The wall loss of ambient particles ranging 0.05 to 0.2㎛ was 1.8~5.4×10^(-3)min^(-1), which was slightly higher than those of ambient gaseous species. The purified air supply system provided high quality of air with NO₂, < 1 ppb, and total hydrocarbons <5 ppb.

      • 제주지방에 있어서 파종기에 따른 겨울작물의 풋베기 생산성

        강영길,조남기,김용찬 濟州大學校 亞熱帶農業硏究所 1999 亞熱帶農業硏究 Vol.16 No.-

        제주지방에서 파종기가 몇 종류의 겨울작물의 풋베기 수량에 미치는 영향을 조사하여 파종기에 알맞은 작물을 선발하고자 1998-1999년에 제주에서 이탈리안 라이그라스(Bamultra), 귀리(올귀리), 유채(Akela), 헤어리 베치(제주수집종), 완두(제주수집증)을 1998년 9월 1일, 10월 3일, 11월 5일에 파종하여 건물, 조단백질, TDN수량 등을 조사한 결과를 요약하면 다음과 같다. 파종기별 ha당 건물, 조단백질, TDN 수량은 9월 1일 파종구에서는 유채가 각각 13,500, 2,656, 8,423kg으로 가장 많았고 이탈리안 라이그라스(9,685, 1,168, 5,945kg), 헤어리 베치(4,706, 904, 2,763, 완두(4,063, 824, 2716kg), 귀리(2,469, 377, 1,618kg)순이었다. 10월 3일 파종구의 건물 및 TDN수량은 이탈리안 라이그라스가 각각 10,028, 6,156kg으로 가장 많았고 유채, 귀리, 헤어리 베치, 완두 순이었으나 조단백질 수량은 유채가 1,475kg으로 가장 많았고 이탈리안 라이그라스, 헤어리 베치, 귀리, 완두 순이었다. 11월 5일 파종구의 경우 이탈리안 라이그라스가 각각 10,115, 1,220, 6,209kg으로 가장 많았으나 귀리, 유채, 헤어리 베치, 완두 순이었다. 이탈리안 라이그라스는 파종기간 건물, 조단백질, TDN수량 등이 별차이가 없었으나, 파종이 늦을수록 귀리의 수량이 많아졌고 유채, 헤어리 베치, 완두의 수량은 적어졌다. 제주지방에 있어서 9월 상순까지 파종할 경우 유채가 유리하고 10월이후에는 이탈리안 라이그라스가 유망할 것이다. A cultivar of Italian ryegrass ('Bamultra'), oat('Olgwiri'), rape ('Akela'), hairy vetch (local collection) and pea (local collection) was seeded on September 1, October 3 and November 5, 1998 at Cheju to evaluate the effects of seeding date on dry forage (DF), crude protein (CP), and total digestible nutrient (TDN) yields of five cool season crops. At September 1 seeding rape produced the greatest DF (13,500 kg/ha), CF (2,656 kg/ha), and TDN (8,423 kg/ha), followed by Italian ryegrass (9,685, 1,168, 5,945 kg/ha), hairy vetch (4,706, 904, 2,763 kg/ha), pea (4,063, 824, 2763 kg/ha), and oat (2,469, 377, 1,618 kg/ha). At October 1 seeding Italian ryegrass yielded the greatest DF (10,028 kg/ha) and TDN (6,156 kg/ha), followed by rape, oat, hairy vetch, and pea while rape had the greatest CF yield (1,475 kg/ha), followed by Italian ryegrass, hairy vetch, oat, and pea. At November 5 seeding Italia ryegrass yielded the greatest DF (10,115 kg/ha), CF (1,220 kg/ha), and TDN (6,209 kg/ha), followed by rape, oat, hairy vetch, and pea. Dry forage, CP and TDN yields of Italian ryegrass were not significantly affected by seeding date. As seeding was delayed, DF, CP and TDN yields of oat increased while those of rape, hairy vetch, and pea decreased. These results suggest that rape can be a suitable forage crop for early seeding (until early September) and Italian ryegrass for late planting (after early October) in Cheju area.

      • 식물체로부터 추출한 물질이 상추 종자의 발아 및 생장에 미치는 영향

        박건남,이민경,황선주,김학윤,이인중,신동현,김길웅 경북대학교 농업과학기술연구소 1999 慶北大農學誌 Vol.17 No.-

        This study was conducted to detect the allelopathic effect of water and ethanol extracts from 4 plant species (Lactuca sativa L., Ambrosia elatior L., Oenothenra odorata Jasp., Ginkgo biloba L.) on germination and growth of lettuce seeds. A little bit higher inhibitory effect was obtained in ethanol extracts rather than water extracts. Allelopathic effects varied in the source of extracts and concentrations of 4 plant species and the highest allelopathic effect appeared in 10% solution, regardless of plant species.

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