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조직확장법,술중 조직확장법 및 술전 봉합법의 임상적 응용에 관한 비교 연구
오석준,하지운,김응춘,서인석,조세흠 大韓成形外科學會 1993 Archives of Plastic Surgery Vol.20 No.3
The purpose of soft tissue defect reconstruction is minimal scar with aesthetic and functional good results. Reconstruction of head and neck, upper extremity, chest, and lower extremity defects has been reported with standard available tissue expansions. Various surgical methods have been used in an attempt to achieve a normallooking skin color, texture, sensation, thickness and same skin adenexa. Therefore, in accordance with defect size and location, the operative method was considered so we select adequate method. Authors achieved good results from 48 cases of tissue expansion, 18 cases of ISLE (intraoperative sustained limited expansion), and 35 cases of presuturing technique. 1)The most common cause of reconstruction for soft tissue defect was post grafted scar 51cases(51%), next was tattoo 20 cases(19.6%), traumatic soft tissue defect 16cases(15.7% ) and nevus 8 cases(7.8%)in order. 2)Males(55.9%)were affected more often than females(44.1%)in the ratio 1, 3 : 1 and the most frequently affected group was the age of 20 to 30 years as 36% . 3)The distribution of incidence and location were as follow : face(39.2%), upper extremity(25.5%), scalp(17.6%), lower extremity(9.8%) and trunk(7.8%). 4)The cause and distribution were scalp in 20 cases(39.2%), face in 40 cases(29.4%) in the post grafted scar, upper extremity 18 cases(90.0%) in the tattoo, upper extremity 4 cases(50.0%), face 2 cases(25.0%) in the nevus and even distribution in the traumatic soft tissue defects. 5)The presuturing technique was best recommended method for soft tissue defect in 4cm diameter lesion on extremity, but ISLE method was used in the open traumatic soft tissue defect. Over 9cm wide scar was resurfaced by expanded skin using tissue expander.
Development of Prototype Multi-channel Digital EIT System with Radially Symmetric Architecture
Oh, Tong-In,Baek, Sang-Min,Lee, Jae-Sang,Woo, Eung-Je,Park, Chun-Jae The Korean Society of Medical and Biological Engin 2005 의공학회지 Vol.26 No.4
We describe the development of a prototype multi-channel electrical impedance tomography (EIT) system. The EIT system can be equipped with either a single-ended current source or a balanced current source. Each current source can inject current between any chosen pair of electrodes. In order to reduce the data acquisition time, we implemented multiple digital voltmeters simultaneously acquiring and demodulating voltage signals. Each voltmeter measures a differential voltage between a fixed pair of adjacent electrodes. All voltmeters are configured in a radially symmetric architecture to optimize the routing of wires and minimize cross-talks. To maximize the signal-to-noise ratio, we implemented techniques such as digital waveform generation, Howland current pump circuit with a generalized impedance converter, digital phase-sensitive demodulation, tri-axial cables with both grounded and driven shields, and others. The performance of the EIT system was evaluated in terms of common-mode rejection ratio, signal-to-noise ratio, and reciprocity error. Future design of a more innovative EIT system including battery operation, miniaturization, and wireless techniques is suggested.
Effects of aqueous extracts from Lonicera japonica and Tussilago farfara on RAW 264.7 Macrophages
( Eung Seok Lee ),( Su Young Yang ),( Yang Chun Park ),( Young Seon Oh ),( Jin Woo Lee ),( Yong Koo Lee ) 대전대학교 한의학연구소 2010 한의학연구소 논문집 Vol.19 No.1
Inhalational drug is an attractive modality for local therapy of pulmonary diseases as well as systemic drug delivery. Flower of Lonicera japonica (FLJ) and flower of Tussilag farfara (FTP) are medicinal herbs for respiratory disease in traditional Korean medicine. As a preliminary study for effective inhalable formulation of FLJ and FTP, this study was to provide the toxicity and anti-inflammatory effect on murine macrophages. The dried FLJ and FTF were extracted with distilled water, filtered and freeze-dried. After treatment with FLJ and FTF extract on RAW 264.7 cells, the cell viabilities were measured by MTT assay. FLJ and FTF did not show cytotoxicity on RAW 264.7 cells. LPS stimulated RAW 264.7 cells were treated with 3 and 30 μg/ml of FLJ or FTF. FLJ and FTF did not inhibit TNT-a and IL-6 secretion in both concentration of treatment. We suggest that FLJ and FTF may be useful drugs for respiratory disease. Future work will focus on the physical characteristics for inhalable formulation.
256-Channel Trans-Admittance Scanner with Lesion Estimation Algorithm for Breast Cancer Detection
Oh, Tong-In,Kim, Kyu-Sik,Lee, Jae-Sang,Woo, Eung-Je,Park, Chun-Jae The Korean Society of Medical and Biological Engin 2005 의공학회지 Vol.26 No.4
Breast cancer detection using electrical impedance techniques is based on numerous experimental findings that cancerous tissues have higher electrical conductivity values than normal tissues. Lately, by taking advantage of the structure of current flows underneath a planar probe of array electrodes, a mathematical formula to find lesions from a measured transadmittance map has been derived. In order to experimentally validate its mathematical analysis and the suggested lesion estimation algorithm, we developed a 256-channel trans-admittance scanner (TAS) for probing anomalies underneath a planar array of electrodes. In this paper, we describe the design and implementation of the TAS. Its performance together with the lesion estimation algorithm was evaluated using saline phantoms. Further studies are proposed to validate the system on human subjects.
Effects of aqueous extracts from Lonicera japonica and Tussilago farfara on RAW 264.7 Macrophages
Lee, Eung-Seok,Yang, Su-Young,Park, Yang-Chun,Oh, Young-Seon,Lee, Jin-Woo,Lee, Yong-Koo Research Institute of Korean Medicine 2010 한의학연구소 논문집 Vol.19 No.1
Inhalational drug is an attractive modality for local therapy of pulmonary diseases as well as systemic drug delivery. Flower of Lonicera japonica (FLJ) and flower of Tussilag farfara (FTF) are medicinal herbs for respiratory disease in traditional Korean medicine. As a preliminary study for effective inhalable formulation of FLJ and FTF, this study was to provide the toxicity and anti-inflammatory effect on murine macrophages. The dried FLJ and FTF were extracted with distilled water, filtered and freeze-dried. After treatment with FLJ and FTF extract on RAW 264.7 cells, the cell viabilities were measured by MTT assay. FLJ and FTF did not show cytotoxicity on RAW 264.7 cells. LPS stimulated RAW 264.7 cells were treated with 3 and $30\;{\mu}g/ml$ of FLJ or FTF. FLJ and FTF did not inhibit TNF-a and IL-6 secretion in both concentration of treatment. We suggest that FLJ and FTF may be useful drugs for respiratory disease. Future work will focus on the physical characteristics for inhalable formulation.
주응식(Eung Sik Ju),김일규(Il Gyu Kim),오영은(Young Eun Oh),이현정(Hyun Jung Lee),이택후(Taek Hu Lee),전상식(Sang Sik Chun) 대한산부인과학회 2001 Obstetrics & Gynecology Science Vol.44 No.2
본원 산부인과에서 최근 10년간 각종 질환으로 수술적 자궁경술을 시행받은 163명을 분석하여 이들 중에서 불임을 주소로하는 자궁내 유착 환자 98명을 대상으로 수술 후의 reproductive outcome을 조사 분석하였다. 자궁내 유착의 정도는 미국불임학회의 기준을 따라 분류하였고 분류에 의하면 자궁내 유착 환자 98명은 각각 mild 29.6%, moderate 43.9%, severe 26.5%의 빈도를 보였다. 자궁내 유착 경우 선행 원인으로는 인공 혹은 자연 임신중절이 대부분을 차지하고 그외에 제왕절개술, 포도상 기태, 골반결핵 등이 있었으나 원인을 정확히 밝힐 수 없는 경우도 일부 있었다. 유착제거술 후 임신율은 전체로는 53.3%, mild, moderate, severe의 경우 각각 84.6%, 45.0%, 33.3%의 임신율을 보였다. 환자에 따라서는 자궁내막증이나 난관폐쇄 등 다른 불임인자를 포함하는 경우도 있어 그 결과의 분석이 어렵고 또한 많은 환자가 추적에서 이탈되어 45.9%(45/98명)만이 추적 조사가 가능하였다. 추적기간은 1.0년 이상을 대상으로 하였고 최장 8.8년간 추적이 가능하였다. 합병증으로는 자궁천공 5례, 호흡곤란 내지 폐부종 2례, 출혈과 방광손상 각각 1례 등으로 나타났다. One hundred sixty three patients were hysteroscoped for various reasons at our department over 10 year period. Ninety eight patients out of 163 who were diagnosed and treated for their intrauterine adhesions(IUAs) by hysteroscopy were analysed retrospectively. Patients were classified as having mild, moderate or severe stage of IUAs according to American Fertility Society classification. Twenty nine patients(29.6%) had mild IUAs, 43 patients (43.9%) had moderate IUAs, and 26 patients(26.5%) were classified as having severe stage IUAs. The predisposing causal factors of IUAs were abortion, full-term delivery, H. mole, pelvic tuberculosis and myomectomy in order of frequency but in eight cases no cause was identified. After hysteroscopic surgery, although high rate(83.9%) of restoration of normal menstruation was attained but term pregnancy rate was only 53.3% and rather high rate (32%) of preterm or abortion were identified and those pregnancy outcomes were correlated with the stage of IUAs. Complications of surgery consisted of uterine or bladder perforation, pulmonary edema and hemorrhage.