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Kinetic Models for Growth and Product Formation on Multiple Substrates
권윤중,Cady R. Engler 한국생물공학회 2005 Biotechnology and Bioprocess Engineering Vol.10 No.6
Hydrolyzates from lignocellulosic biomass contain a mixture of simple sugars; the predominant ones being glucose, cellobiose and xylose. The fermentation of such mixtures to ethanol or other chemicals requires an understanding of how each of these substrates is utilized. Candida lusitaniae can efficiently produce ethanol from both glucose and cellobiose and is an attractive organism for ethanol production. Experiments were performed to obtain kinetic data for ethanol production from glucose, cellobiose and xylose. Various combinations were tested in order to determine kinetic behavior with multiple carbon sources. Glucose was shown to repress the utilization of cellobiose and xylose. However, cellobiose and xylose were simultaneously utilized after glucose depletion. Maximum volumetric ethanol production rates were 0.56, 0.33, and 0.003 g/L·h from glucose, cellobiose and xylose, respectively. A kinetic model based on cAMP mediated catabolite repression was developed. This model adequately described the growth and ethanol production from a mixture of sugars in a batch culture.
Kinetic Models for Growth and Product Formation on Multiple Substrates
Kwon, Yun-Joong,Engler, Cady R. The Korean Society for Biotechnology and Bioengine 2005 Biotechnology and Bioprocess Engineering Vol.10 No.6
Hydrolyzates from lignocellulosic biomass contain a mixture of simple sugars; the predominant ones being glucose, cellobiose and xylose. The fermentation of such mixtures to ethanol or other chemicals requires an understanding of how each of these substrates is utilized. Candida lusitaniae can efficiently produce ethanol from both glucose and cellobiose and is an attractive organism for ethanol production. Experiments were performed to obtain kinetic data for ethanol production from glucose, cellobiose and xylose. Various combinations were tested in order to determine kinetic behavior with multiple carbon sources. Glucose was shown to repress the utilization of cellobiose and xylose. However, cellobiose and xylose were simultaneously utilized after glucose depletion. Maximum volumetric ethanol production rates were 0.56, 0.33, and 0.003 g/L h from glucose, cellobiose and xylose, respectively. A kinetic model based on cAMP mediated catabolite repression was developed. This model adequately described the growth and ethanol production from a mixture of sugars in a batch culture.
Stack,James P.,Engler,Cady R.,Albert,Carcia Ⅲ,Koh,Jeong-Sam 濟州大學校 亞熱帶農業硏究所 1990 亞熱帶農業硏究 Vol.7 No.-
땅콩에서 分離한 곰팡이를 사용하여 免疫抑制活性을 갖는 抗菌性代謝産物의 生産을 위한 振揚培地條件을 檢討하였다. 耐熱性인 이 菌을 Penicillium citrinum var Pa-6으로 同定하였으며, 窒素源을 制限한 培地에서 35℃, 2주간 培養에서 最大의 抗菌作用을 나타냈다. 最適培地組成을 檢査한 結果, 1.5% 칼락토스와 0.5% 포도당을 炭素源으로 하여 C/N비율이 50이 되도록 0.046% NH₄NO₃를 窒素源으로 添加하고, 10mM 無機隣酸과 無機鹽類를 少量 첨가한 培地였다. 또한 페닐알라닌, 글루타민 또는 타이로신과 같은 몇 종류의 아미노산을 添加함으로써 抗菌作用은 배양중에 빨리 나타남을 알 수 있었다. Cultural conditions of shake-flask culture for the production of antimicrobial metabolites containing immunosuppressive activities by fungi isolated from peanut seeds were investigated. The thermotolerant stain, identified as Penicillium citrinum var Pa-6, produced maximum antimicrobial metabolites at 35℃ after 2 weeks on nitrogen-limiting medium. According to cultural conditions, optimum medium compositions for antimicrobial metabolites production were defind as follws; 1.5% of galactose with 0.5% dextrose, 0.046$ NH₄NO₃(C/N ratio 50), 10mM of Pi and trace elements. The expression of antimicrobial actvities were appeared sooner than control during cultivation with the addition of some amino acid such as phenylalanine, glutamine or tyrosine.
(Kwon Bok Lee,(Cady Engler,(Jae E . Yang,(Shin Woo Lee,(Yong Ha Park 한국응용생명화학회 2001 Journal of Applied Biological Chemistry (J. Appl. Vol.44 No.2
Capsaicin synthesis by suspension cultured cells of Jalapeno pepper (Capcicum annuum L.) was assessed in vitro under various conditions including temperature (23 and 30℃), light intensity (with light and without light), and shaking speed (110 and 200 rpm).
NFC based Alarm Patching System for Regular Time Management
Jung, Yong Gyu,Choi, Eun Hee,Kang, Min Soo,Cady, Jennifer J. The Institute of Internet 2015 International journal of advanced smart convergenc Vol.4 No.1
Most people do not think seriously about the concept of time management, just to spend the precious time sheets. Regular life can sustain mental and physical health. That's why time management is an important factor in living. In the thesis, smart alarm patch is designed using a wireless communication NFC technology that gradually develop and attract attention. Due to the alarm, regular hours is helped to improve the quality of life. For this, analysis was performed using the UML in this system, linked to the smart alarm system patches and NFC technology, Java Script language, Adobe Muse CC was used embody web document and mobile content.
NFC based Alarm Patching System for Regular Time Management
Yong Gyu Jung,Eun Hee Choi,Min Soo Kang,Jennifer J. Cady 한국인터넷방송통신학회 2015 Journal of Advanced Smart Convergence Vol.4 No.1
Most people do not think seriously about the concept of time management, just to spend the precious time sheets. Regular life can sustain mental and physical health. That's why time management is an important factor in living. In the thesis, smart alarm patch is designed using a wireless communication NFC technology that gradually develop and attract attention. Due to the alarm, regular hours is helped to improve the quality of life. For this, analysis was performed using the UML in this system, linked to the smart alarm system patches and NFC technology, Java Script language, Adobe Muse CC was used embody web document and mobile content.
Abu-Zayyad, T.,Aida, R.,Allen, M.,Anderson, R.,Azuma, R.,Barcikowski, E.,Belz, J. W.,Bergman, D. R.,Blake, S. A.,Cady, R.,Cheon, B. G.,Chiba, J.,Chikawa, M.,Cho, E. J.,Cho, W. R.,Fujii, H.,Fujii, T.,F IOP Publishing 2013 The Astrophysical journal Vol.777 No.2
<P>We search for correlations between the positions of extragalactic objects and the arrival directions of ultra-high energy cosmic rays (UHECRs) with primary energy E >= 40 EeV as observed by the surface detector array of the Telescope Array (TA) experiment during the first 40 months of operation. We examine several public astronomical object catalogs, including the Veron-Cetty and Veron catalog of active galactic nuclei. We count the number of TA events correlated with objects in each catalog as a function of three parameters: the maximum angular separation between a TA event and an object, the minimum energy of the events, and the maximum redshift of the objects. We determine the combination of these parameters that maximizes the correlations, and we calculate the probability of having the same levels of correlations from an isotropic distribution of UHECR arrival directions. No statistically significant correlations are found when penalties for scanning over the above parameters and for searching in several catalogs are taken into account.</P>
Abu-Zayyad, T.,Aida, R.,Allen, M.,Anderson, R.,Azuma, R.,Barcikowski, E.,Belz, J.W.,Bergman, D.R.,Blake, S.A.,Cady, R.,Cheon, B.G.,Chiba, J.,Chikawa, M.,Cho, E.J.,Cho, W.R.,Fujii, H.,Fujii, T.,Fukuda, North-Holland ; Elsevier Science Ltd 2013 Astroparticle physics Vol.48 No.-
We present a measurement of the energy spectrum of ultra-high-energy cosmic rays performed by the Telescope Array experiment using monocular observations from its two new FADC-based fluorescence detectors. After a short description of the experiment, we describe the data analysis and event reconstruction procedures. Since the aperture of the experiment must be calculated by Monte Carlo simulation, we describe this calculation and the comparisons of simulated and real data used to verify the validity of the aperture calculation. Finally, we present the energy spectrum calculated from the merged monocular data sets of the two FADC-based detectors, and also the combination of this merged spectrum with an independent, previously published monocular spectrum measurement performed by Telescope Array's third fluorescence detector [T. Abu-Zayyad et al., The energy spectrum of Telescope Array's middle drum detector and the direct comparison to the high resolution fly's eye experiment, Astroparticle Physics 39 (2012) 109-119, http://dx.doi.org/10.1016/j.astropartphys.2012.05.012, Available from: <arXiv:1202.5141>]. This combined spectrum corroborates the recently published Telescope Array surface detector spectrum [T. Abu-Zayyad, et al., The cosmic-ray energy spectrum observed with the surface detector of the Telescope Array experiment, ApJ 768 (2013) L1, http://dx.doi.org/10.1088/2041-8205/768/1/L1, Available from: <arXiv:1205.5067>] with independent systematic uncertainties.
THE COSMIC-RAY ENERGY SPECTRUM OBSERVED WITH THE SURFACE DETECTOR OF THE TELESCOPE ARRAY EXPERIMENT
Abu-Zayyad, T.,Aida, R.,Allen, M.,Anderson, R.,Azuma, R.,Barcikowski, E.,Belz, J. W.,Bergman, D. R.,Blake, S. A.,Cady, R.,Cheon, B. G.,Chiba, J.,Chikawa, M.,Cho, E. J.,Cho, W. R.,Fujii, H.,Fujii, T.,F IOP Publishing 2013 ASTROPHYSICAL JOURNAL LETTERS - Vol.768 No.1