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( Fen Wang ),( Yang Lu ),( Zhongqi Wang ),( Jinmei Tian ) 한국인터넷정보학회 2022 KSII Transactions on Internet and Information Syst Vol.16 No.1
Public key encryption with keyword search (PEKS) allows a user to make search on ciphertexts without disclosing the information of encrypted messages and keywords. In practice, cryptographic operations often occur on insecure devices or mobile devices. But, these devices face the risk of being lost or stolen. Therefore, the secret keys stored on these devices are likely to be exposed. To handle the key exposure problem in PEKS, the notion of key-updatable PEKS (KU-PEKS) was proposed recently. In KU-PEKS, the users’ keys can be updated as the system runs. Nevertheless, the existing KU-PEKS framework has some weaknesses. Firstly, it can’t update the keyword ciphertexts on the storage server without leaking keyword information. Secondly, it needs to send the search tokens to the storage server by secure channels. Thirdly, it does not consider the search token security. In this work, a new PEKS framework named key-updatable and ciphertext-sharable PEKS (KU-CS-PEKS) is devised. This novel framework effectively overcomes the weaknesses in KU-PEKS and has the ciphertext sharing function which is not supported by KU-PEKS. The security notions for KU-CS-PEKS are formally defined and then a concrete KU-CS-PEKS scheme is proposed. The security proofs demonstrate that the KU-CS-PEKS scheme guarantees both the keyword ciphertext privacy and the search token privacy. The experimental results and comparisons bear out that the proposed scheme is practicable.
Security Threats among DICOM Imaging Communications in Public Networks
Feng Zhou,Zhongqi Zhang,Jin Wang,Bin Li,Jeong-Uk Kim 보안공학연구지원센터 2014 International Journal of Future Generation Communi Vol.7 No.6
Picture archiving and communication systems (PACS) require high-speed networks to transmit large image files between components. Image-data transmission from one site to another through public network is usually characterized in term of privacy, authenticity, and integrity. However, public network’s security issues had always been the significant problems. Recent years, IPv6 brings significant improvements in mechanisms for assuring a higher level of security and confidentiality of the transmitted information. Thus, it is still necessary to take care of some particular aspects. In this paper, we first analyzes how actual security threats and different types of attacks affect IPv6 networks while transmitting Digital Imaging and Communications in Medicine (DICOM) files through the public Internet. Second, illustrate some shortcomings of IPv6 and IPv6’s traffic loads. Finally, some possible solutions against a number of security threats in IPv6 DICOM files transmitting networks have been given.
Zhengxia Wang,Ningfei Ji,Zhongqi Chen,Zhixiao Sun,Chaojie Wu,Wenqing Yu,Fan Hu,Mao Huang,Mingshun Zhang 대한천식알레르기학회 2020 Allergy, Asthma & Immunology Research Vol.12 No.5
Purpose: CD4+T cells are essential in the pathogenesis of allergic asthma. We have previously demonstrated that microRNA-1165-3p (miR-1165-3p) was significantly reduced in T-helper type (Th) 2 cells and that miR-1165-3p was a surrogate marker for atopic asthma. Little is known about the mechanisms of miR-1165-3p in the regulation of Th2-dominated allergic inflammation. We aimed to investigate the associations between Th2 differentiation and miR-1165b-3p in asthma as well as the possible mechanisms. Methods: CD4+ naïve T cells were differentiated into Th1 or Th2 cells in vitro. MiR-1165-3p was up-regulated or down-regulated using lentiviral systems during Th1/Th2 differentiation. In vivo, the lentiviral particles with the miR-1165-3p enhancer were administered by tail vein injection on the first day of a house dust mite -induced allergic airway inflammation model. Allergic inflammation and Th1/Th2 differentiation were routinely monitored. To investigate the potential targets of miR-1165-3p, biotin-microRNA pull-down products were sequenced, and the candidates were further verified with a dual-luciferase reporter assay. The roles of a target protein phosphatase, Mg2+/Mn2+-dependent 1A (PPM1A), in Th2 cell differentiation and allergic asthma were further explored. Plasma PPM1A was determined by ELISA in 18 subjects with asthma and 20 controls. Results: The lentivirus encoding miR-1165-3p suppressed Th2-cell differentiation in vitro. In contrast, miR-1165-3p silencing promoted Th2-cell development. In the HDM-induced model of allergic airway inflammation, miR-1165-3p up-regulation was accompanied by reduced airway hyper-responsiveness, serum immunoglobulin E, airway inflammation and Th2-cell polarization. IL-13 and PPM1A were the direct targets of miR-1165-3p. The expression of IL-13 or PPM1A was inversely correlated with that of miR-1165-3p. PPM1A regulated the signal transducer and activator of transcription and AKT signaling pathways during Th2 differentiation. Moreover, plasma PPM1A was significantly increased in asthmatic patients. Conclusions: MiR-1165-3p negatively may regulate Th2-cell differentiation by targeting IL-13 and PPM1A in allergic airway inflammation.
An enhanced fall detection system for elderly person monitoring using consumer home networks
Jin Wang,Zhongqi Zhang,Bin Li,Sungyoung Lee,Sherratt, R. Simon IEEE 2014 IEEE transactions on consumer electronics Vol.60 No.1
<P>Various fall-detection solutions have been previously proposed to create a reliable surveillance system for elderly people with high requirements on accuracy, sensitivity and specificity. In this paper, an enhanced fall detection system is proposed for elderly person monitoring that is based on smart sensors worn on the body and operating through consumer home networks. With treble thresholds, accidental falls can be detected in the home healthcare environment. By utilizing information gathered from an accelerometer, cardiotachometer and smart sensors, the impacts of falls can be logged and distinguished from normal daily activities. The proposed system has been deployed in a prototype system as detailed in this paper. From a test group of 30 healthy participants, it was found that the proposed fall detection system can achieve a high detection accuracy of 97.5%, while the sensitivity and specificity are 96.8% and 98.1% respectively. Therefore, this system can reliably be developed and deployed into a consumer product for use as an elderly person monitoring device with high accuracy and a low false positive rate.</P>