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( Yuji Fujita ),( Akito Iwasaki ),( Takamitsu Sato ),( Toshio Fujisawa ),( Yusuke Sekino ),( Kunihiro Hosono ),( Nobuyuki Matsuhashi ),( Kentaro Sakamaki ),( Atsushi Nakajima ),( Kensuke Kubota ) 대한소화기학회 2017 Gut and Liver Vol.11 No.1
Background/Aims: There is no consensus for using endoscopic papillary large balloon dilation (EPLBD) in patients without dilatation of the lower part of the bile duct (DLBD). We evaluated the feasibility and safety of EPLBD for the removal of difficult bile duct stones (diameter ≥10 mm) in patients without DLBD. Methods: We retrospectively reviewed the records of 209 patients who underwent EPLBD for the removal of bile duct stones from October 2009 to July 2014. Primary outcomes were the clearance rate and additional mechanical lithotripsy. Secondary outcomes were the incidence of complications and recurrence rate. Results: Fiftyseven patients had DLBD (27.3%), and 152 did not have DLBD (72.7%). There were no significant differences in the overall success rate or the use of mechanical lithotripsy. Success rate during the first session and procedure time were better in the DLBD than the without-DLBD group (75.7% vs 66.7%, 48.1±23.0 minutes vs 58.4±31.7 minutes, respectively). As for complications, there were no significant differences in the incidence of pancreatitis, perforation or bleeding after endoscopic retrograde cholangiopancreatography. The recurrence rate did not differ significantly between the two groups. Conclusions: EPLBD is a useful and safe method for common bile duct stone removal in patients without DLBD. (Gut Liver 2017;11:149-155)
Clinical outcomes of permanent stenting with endoscopic ultrasound gallbladder drainage
Eisuke Suzuki,Yuji Fujita,Kunihiro Hosono,Yuji Koyama,Seitaro Tsujino,Takuma Teratani,Atsushi Nakajima,Nobuyuki Matsuhashi 대한소화기내시경학회 2023 Clinical Endoscopy Vol.56 No.5
Background/Aims: Endoscopic ultrasound gallbladder drainage (EUS-GBD) is gaining attention as a treatment method for cholecystitis. However, only a few studies have assessed the outcomes of permanent stenting with EUS-GBD. Therefore, we evaluated the clinicaloutcomes of permanent stenting using EUS-GBD. Methods: This was a retrospective, single-center cohort study. The criteria for EUS-GBD at our institution are a high risk for surgery,inability to perform surgery owing to poor performance status, and inability to obtain consent for emergency surgery. EUS-GBD wasperformed using a 7-Fr double-pigtail plastic stent with a dilating device. The primary outcomes were the recurrence-free rate of cholecystitisand the late-stage complication-avoidance rate. Secondary outcomes were technical success, clinical success, and procedural adverseevents. Results: A total of 41 patients were included in the analysis. The median follow-up period was 168 (range, 10–1,238) days. The recurrence-free and late-stage complication-avoidance rates during the follow-up period were 95% (38 cases) and 90% (36 cases), respectively. There were only two cases of cholecystitis recurrence during the study period. Conclusions: EUS-GBD using double-pigtail plastic stent was safe and effective with few complications, even in the long term, in patientswith acute cholecystitis.
관내 예혼함 화염에서 외부 CO₂ 레이저 조사에 의한 화염면 진동의 동적거동
박준성(June Sung Park),Fujita Osamu,Nakamura Yuji,Ito Hiroyuki 한국연소학회 2009 KOSCOSYMPOSIUM논문집 Vol.- No.39
Experiments in premixed C₂H₄/CO₂-O₂ flames (Le < 1) in a tube have been conducted, the mixture was ignited at the top, open end of and propagating downwardly toward the closed end. to investigate the exact motion of flame tip fluctuations at the initial moment of irradiating CO₂ laser, the completely flat flame front is selected as a default flame, which is corresponding to the primary acoustic instability as reported by Searby.[1] During the laser exposure to the unburned mixture, the flame fronts had extremely unstable behaviors, resulting in a strong turbulent flame eventually through the secondary acoustic instability. To elucidate the effect of flame curvatures, the flame velocity and curvature prior to the secondary acoustic instability were analyzed by using captured high speed camera images. the results showed that a sudden acceleration at advancing waves was observed. And then, there was the time lag between the flame velocity and curvature, indicating the increase in the flame velocity even with decreasing flame curvature. these behaviors are closely relevant not only to the diffusive-thermal effects but also to the acoustic waves. the plausible mechanism was proposed in this paper based on the acoustic influence.
Uchino, Junji,Hirano, Ryosuke,Tashiro, Naoki,Yoshida, Yuji,Ushijima, Shinichiro,Matsumoto, Takemasa,Ohta, Keiichi,Nakatomi, Keita,Takayama, Koichi,Fujita, Masaki,Nakanishi, Yoichi,Watanabe, Kentaro Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.8
Aims and Background: To evaluate the efficacy of a combination of aprepitant and conventional antiemetic therapy in patients with advanced or recurrent lung cancer receiving moderately emetogenic chemotherapy (MEC). Methods: Patients with advanced or recurrent lung cancer who were treated with MEC regimens at the Department of Respiratory Medicine, Fukuoka University Hospital, were included and classified into the following groups: control group (treatment: 5-HT3 receptor antagonists + dexamethasone) and aprepitant group (treatment: 5-HT3 receptor antagonists + dexamethasone + aprepitant). The presence or absence of chemotherapy-induced nausea and vomiting (CINV) was evaluated according to the Common Terminology Criteria for Adverse Events (CTCAE) v4.0; patients with grade 1 or above were considered positive for CINV. Food intake per day, completion of planned chemotherapy, and progression-free survival (PFS) achieved by chemotherapy were investigated. Results: The complete suppression rate of nausea in the aprepitant group was significantly higher than that in the control group (p = 0.0043). Throughout the study, the food intake in the aprepitant group was greater than that in the control group, with the rate being significantly higher, in particular, on day 5 (p = 0.003). The completion rate of planned chemotherapy was also higher in the aprepitant group (p = 0.042). PFS did not differ significantly, but tended to be improved in the aprepitant group. Conclusions: The aprepitant group showed significantly higher complete suppression of nausea, food intake on day 5, and completion of planned chemotherapy than the control group.
Influence of the Internal Current on the Sintering Behavior of ZnO Ceramics Sintered by PCS Method
Misawa Tatsuya,Shikatani Noboru,Kawakami Yuji,Enjoji Takashi,Ohtsu Yasunori,Fujita Hiroharu 한국분말야금학회 2006 한국분말야금학회 학술대회논문집 Vol.2006 No.1
The influence of the internal current for the ZnO ceramics on the sintering behavior by pulse current sintering (PCS) method was investigated. To clear the dependence of inner current on the sintering behavior of ZnO ceramics, direct measurement of electric resistance of ZnO specimen under sintering by SPS device was carried out. It was observed that electric resistance of specimen decreases with increase in the temperature. The electric resistance begins to decrease from the low temperature of . The internal structure of sintered ZnO ceramics changed by the control of the internal current in the specimen using plate.