http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
( Yuechao Ma ),( Qixin Chen ),( Yi Cui ),( Lihong Du ),( Tuo Shi ),( Qingyang Xu ),( Qian Ma ),( Xixian Xie ),( Ning Chen ) 한국미생물생명공학회(구 한국산업미생물학회) 2018 Journal of microbiology and biotechnology Vol.28 No.11
Corynebacterium glutamicum is an excellent platform for the production of amino acids, and is widely used in the fermentation industry. Most industrial strains are traditionally obtained by repeated processes of random mutation and selection, but the genotype of these strains is often unclear owing to the absence of genomic information. As such, it is difficult to improve the growth and amino acid production of these strains via metabolic engineering. In this study, we generated a complete genome map of an industrial L-valine-producing strain, C. glutamicum XV. In order to establish the relationship between genotypes and physiological characteristics, a comparative genomic analysis was performed to explore the core genome, structural variations, and gene mutations referring to an industrial L-leucine-producing strain, C. glutamicum CP, and the widely used C. glutamicum ATCC 13032. The results indicate that a 36,349 bp repeat sequence in the CP genome contained an additional copy each of lrp and brnFE genes, which benefited the export of L-leucine. However, in XV, the kgd and panB genes were disrupted by nucleotide insertion, which increase the availability of precursors to synthesize L-valine. Moreover, the specific amino acid substitutions in key enzymes increased their activities. Additionally, a novel strategy is proposed to remodel central carbon metabolism and reduce pyruvate consumption without having a negative impact on cell growth by introducing the CP-derived mutant H+/citrate symporter. These results further our understanding regarding the metabolic networks in these strains and help to elucidate the influence of different genotypes on these processes.
Yifang Yan,Yuechao Ma 제어·로봇·시스템학회 2016 International Journal of Control, Automation, and Vol.14 No.5
In this paper, the problem of observer-based H¥ guaranteed cost control for uncertain singular timedelaysystems with actuator saturation is concerned. A delay-dependent sufficient condition is proposed, whichguarantees that the closed-loop system is admissible via Lyapunov theory and linear matrix inequality (LMI) approach. Then, with this condition, the estimation of stability region, the upper bound of cost function and the designmethod of observer-based H¥ guaranteed cost controller are given by solving linear matrix inequalities and convexoptimization problems. Finally, numerical examples are provided to demonstrate the effectiveness of the proposedmethod.
Sampled-data Robust H∞ Control for T-S Fuzzy Time-delay Systems with State Quantization
Xiaojing Han,Yuechao Ma 제어·로봇·시스템학회 2019 International Journal of Control, Automation, and Vol.17 No.1
This paper investigates the sampled-data robust H∞ control for T-S fuzzy time-delay systems with statequantization. Based on a modified Lyapunov-Krasovskii function(LKF), which is fully considered the characteristicsof sample-data and state quantization, a sample-data and state quantized controller is designed. By introducingthe free weighting matrices, some integral techniques and modified inequalities, the results in this paper are lessconservative than other existing results. At the end of the paper, two examples are given to show the effectivenessand superiority of the proposed methods.
Yutong Zhang,Yuechao Ma,Lei Fu,Wenying Zhao 제어·로봇·시스템학회 2019 International Journal of Control, Automation, and Vol.17 No.8
This paper is concerned with the reliable robust control for semi-Markovian jump sampled-data systems. A mode-dependent Lyapunov-Krasovskii function (LKF) which fully capture the available characteristics of real sampling period is constructed. Based on the LKF approach, Newton-Leibniz condition and convex combination method, less conservative sufficient conditions are presented, which ensure that the closed-loop systems are robust asymptotically stable and extended-dissipativity. Then, actuator failures are taken into consideration, the desired sampled-data controller can be obtained by solving the linear matrix inequalities (LMIs). Finally, two numerical examples are given to illustrate the effectiveness of the proposed method.