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Simple and Direct Quantitative Analysis for Quinidine Drug in Fish Tissues
( Yuan-chin Chen ),( Hani Nasser Abdelhamid ),( Hui-fen Wu ) 한국질량분석학회 2017 Mass spectrometry letters Vol.8 No.1
Analysis of quinidine for fish tissues using single drop microextraction (SDME) coupled with atmospheric pressure matrix assisted laser desorption/ionization mass spectrometry (AP-MALDI-MS) are reported. Optimization conditions; such as extraction solvent, extraction time, pH of the aqueous solution, salt additions (NaCl), stirring rate, matrix type and concentration are investigated. Linear dynamic range (μM), limit of detection, relative recovery%, and enrichment factor are 0.08-9.2, 0.05, 94.8±3.1- 98.5±3.3%, 4.34±0.28-4.40±0.30, respectively. SDME-AP-MALDI-MS shows good intraday and interday reproducibility.
Simple and Direct Quantitative Analysis for Quinidine Drug in Fish Tissues
Chen, Yuan-Chin,Abdelhamid, Hani Nasser,Wu, Hui-Fen Korean Society for Mass Spectrometry 2017 Mass spectrometry letters Vol.2 No.1
Analysis of quinidine for fish tissues using single drop microextraction (SDME) coupled with atmospheric pressure matrix assisted laser desorption/ionization mass spectrometry (AP-MALDI-MS) are reported. Optimization conditions; such as extraction solvent, extraction time, pH of the aqueous solution, salt additions (NaCl), stirring rate, matrix type and concentration are investigated. Linear dynamic range (${\mu}M$), limit of detection, relative recovery%, and enrichment factor are 0.08-9.2, 0.05, $94.8{\pm}3.1-98.5{\pm}3.3%$, $4.34{\pm}0.28-4.40{\pm}0.30$, respectively. SDME-AP-MALDI-MS shows good intraday and interday reproducibility.
A Conference Key Distribution Scheme Using Interpolating Polynomials
Chin-Chen Chang,Chu-Hsing Lin,Chien-Yuan Chen 보안공학연구지원센터 2007 International Journal of Security and Its Applicat Vol.1 No.2
Conference keys are secret keys used by a group of users commonly and with which they can encipher (or decipher) messages such that communications are secure. Based on the Diffie and Hellman’s PKDS, a conference key distribution scheme is presented in this paper. A sealed lock is used to lock the conference key in such a way that only the private keys of the invited members are matched. Then the sealed lock is thus made public or distributed to all the users, only legitimate users can disclose it and obtain the conference key. In our scheme, the construction of a sealed lock is simple and the revelation of a conference key is efficient
Yuan-Hwa Chou,Po-Chung Chu,Szu-Wei Wu,Jen-Chin Lee,Yi-Hsuan Lee,I-Wen Sun,Chen-Lin Chang,Chien-Liang Huang,I-Chao Liu,Chia-Fen Tsai,Yung-Chieh Yen 대한정신약물학회 2015 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.13 No.2
Bipolar disorder (BD) is a major psychiatric disorder that is easily misdiagnosed. Patient adherence to a treatment regimen is of utmost importance for successful outcomes in BD. Several trials of antipsychotics suggested that depot antipsychotics, including long-acting first- and second-generation agents, are effective in preventing non-adherence, partial adherence, and in reducing relapse in BD. Various long-acting injectable (LAI) antipsychotics are available, including fluphenazine decanoate, haloperidol decanoate, olanzapine pamoate, risperidone microspheres, paliperidone palmitate, and aripiprazole monohydrate. Due to the increasing number of BD patients receiving LAI antipsychotics, treatment guidelines have been developed. However, the clinical applicability of LAI antipsychotics remains a global cause for concern, particularly in Asian countries. Expert physicians from Taiwan participated in a consensus meeting, which was held to review key areas based on both current literature and clinical practice. The purpose of this meeting was to generate a practical and implementable set of recommendations for LAI antipsychotic use to treat BD; target patient groups, dosage, administration, and adverse effects were considered. Experts recommended using LAI antipsychotics in patients with schizophrenia, rapid cycling BD, BD I, and bipolar-type schizoaffective disorder. LAI antipsychotic use was recommended in BD patients with the following characteristics: multiple episodes and low adherence; seldom yet serious episodes; low adherence potential per a physician’s clinical judgment; preference for injectable agents over oral agents; and multiple oral agent users still experiencing residual symptoms.
Order Imbalances in Options and Volatility Risk Premium on Equity Index
Chin-Ho Chen,Huimin Chung,Wen-Liang G. Hsieh,Shu-Fang Yuan 한국재무학회 2011 한국재무학회 학술대회 Vol.2011 No.09
This study explores the impact of aggregate daily order imbalances in options on volatility risk premium on its underlying index. Two types of volatility risk premium, ex-post and ex-ante volatility risk premiums, are included to address this issue. Based on Taiwan stock index and options (TXO) data over the period from January 1, 2005 to December 31, 2009, several interesting results emerge. First, order imbalances in near-month options, especially for call options’, have a predominant influence on ex-post and ex-ante volatility risk premiums. Next, order imbalances of near-month options in either direction, excess buy orders or excess sell order, have distinct effect on volatility risk premium. Overall, the increased level of excess buy orders drives ex-post and ex-ante volatility risk premiums upward, but downward only for excess sell orders in call options. Finally, ex-post and ex-ante volatility risk premiums are positively related to order imbalances of near-month options in respond to continuous price variations. Nonetheless, there is no significant relation for index price jumps.
Chen-Kuo Chiang,Chien-Hung Wu,Chin-Chien Liu,Jin-Fu Lin,Chien-Lun Yang,Jiun-Yuan Wu,Shui-Jinn Wang 대한금속·재료학회 2012 ELECTRONIC MATERIALS LETTERS Vol.8 No.5
The NH3 thermal annealing and decoupled plasma nitridation (DPN) processes are compared for the equivalent oxide thickness (EOT) scaling of atomic-layer-deposited hafnium zirconate (HfZrO2) gate dielectric. Detailed physical, optical, and electrical characteristics of nitrided HfZrO2 (HfZrON) film are reported. It is found that DPN can yield a thinner SiOx interfacial layer (IL) (about 0.12 nm more in terms of EOT scaling)and a more densified HfZrO2 layer compared to those obtained using NH3 thermal annealing at a 16% nitrogen dose. NH3 thermal nitridation causes a large nitrogen distribution tail at the SiOx IL/Si substrate interface and increases leakage current, which suppresses EOT scalability.
2D-to-3D Conversion System using Depth Map Enhancement
( Ju-chin Chen ),( Meng-yuan Huang ) 한국인터넷정보학회 2016 KSII Transactions on Internet and Information Syst Vol.10 No.3
This study introduces an image-based 2D-to-3D conversion system that provides significant stereoscopic visual effects for humans. The linear and atmospheric perspective cues that compensate each other are employed to estimate depth information. Rather than retrieving a precise depth value for pixels from the depth cues, a direction angle of the image is estimated and then the depth gradient, in accordance with the direction angle, is integrated with superpixels to obtain the depth map. However, stereoscopic effects of synthesized views obtained from this depth map are limited and dissatisfy viewers. To obtain impressive visual effects, the viewer`s main focus is considered, and thus salient object detection is performed to explore the significance region for visual attention. Then, the depth map is refined by locally modifying the depth values within the significance region. The refinement process not only maintains global depth consistency by correcting non-uniform depth values but also enhances the visual stereoscopic effect. Experimental results show that in subjective evaluation, the subjectively evaluated degree of satisfaction with the proposed method is approximately 7% greater than both existing commercial conversion software and state-of-the-art approach.