Mycobacterium intracellulare에 의한 요추부 척추염 1예

장은영,김미영,김정욱,송은희,백관미,정용필,성흥섭,김미나,김양수,우준희,이상호 대한감염학회 2007 감염과 화학요법 Vol.39 No.3

비결핵성 미코박테리아에 의한 척추염에 대한 증례 보고가 국내에서는 아직 없었다. 저자들은 기저질환이 없는 환자에서 M. intracellulare에 의한 척추염을 rpoB 유전자에 대한 PCR-RFLP 방법을 통해 진단하였고 수술적 치료와 3제 병합 항균 요법으로 성공적인 임상 경과를 보인 1예를 경험하였기에 보고하는 바이다. We report a case of vertebral osteomyelitis due to Mycobacterium intracellulare in a 60-year-old man without predisposing conditions. He was successfully treated with surgical excision of the inflamed tissue and combined antimycobacterial therapy consisting of clarithromycin, ethambutol, and rifampin. In this case, polymerase chain reaction-restriction fragment length polymorphism analysis (PCR-RFLP) based on the rpo B gene of cultured isolates allowed rapid identification of M. intracellulare. Although very rare, nontuberculous mycobacteria (NTM) should be suspected as a causative pathogen of vertebral osteomyelitis. To the best of our knowledge, this is the first case of vertebral osteomyelitis caused by NTM reported in the Korean literature.

연구논문 : 대학생들의 인터넷 중독에 영향을 미치는 요인에 대한 연구

권미영 ( Mi Young Kwon ),황지영 ( Ji Young Hwang ),정혜윤 ( Hye Yoon Jung ),송시형 ( Shi Hyeong Song ) 극동대학교 사회복지연구소 2013 글로벌사회복지연구 Vol.3 No.2

본 논문의 목적은 대학생의 인터넷 중독에 영향을 주는 요인에 대한 분석을 통해 대학생의 정신건강을 위한 공적프로그램 도입에 대한 함의를 제공하는 것이다. 분석자료는 을지대학교 강남 을지 병원 중독연구소에서 대학생 453명을 대상으로한 설문지이다. 설문조사에 사용된 설문지는 인터넷 중독을 측정하는 인터넷 중독 척도(Young척도), 불안을 측정하는 불안척도(STAI)와 우울을 측정하는 Beck의 우울척도(BDI)로 구성되었다. 분석결과 첫째, 연령 및 학년은 인터넷 중독에 유의미한 영향을 미쳤다. 둘째, 나이가 어릴수록, 학년이 낮을수록 불안과 우울에 빠지기 쉬웠다. 셋째, 무엇보다 불안이 대학생의 인터넷 중독에 가장 큰 영향을 미치는 요인이었다. The purpose of this research to suggest implications on introduction of public-program for college students` mental health through analysing the factors which impact on internet addiction of college students. The analysing data is questionnaire intended to 453 college students in Kang- Nam Eulji hospital addiction institute. The questionnaire consisted of internet addiction scale (Young-scale), anxiety scale (STAI) and depression scale (BDI). This study reveals three main findings. Firstly, age and grade have an effect on internet addiction. Second, the younger, the lower grade, they are likely to be depressed and anxiety. Third, most of all, the anxiety has the most effect on internet addiction of college students.

남자 알코올 의존 환자의 기질적 특성에 관한 연구

김성곤,민영기,이덕기,김미영,송영상,권도훈,고영훈,박제민,정병선 대한생물치료정신의학회 2003 생물치료정신의학 Vol.9 No.1

목 적: 본 연구의 목적은 한국인 남자 알코올 의존 환자의 기질적 특성을 Temperament and Character Inventory(TCI)를 이용하여 조사하는 것이다. 방 법: DSM-Ⅳ 진단 기준에 맞는 알코올 의존 환자 30명과 정상인 36명을 대상으로 연구학적 특성을 조사하고, 기질적 특성을 한글판 TCI를 이용하여 조사하였다. 모든 대상자의 나이는 30~60세였다. 결 과: 1) 두 군간 평균 나이는 유의한 차이가 없었으나, 교육 정도와 결혼을 유지하고 있는 비율 및 취업률은 알코올 의존군이 정상 대조군에 비해 유의하게 낮았다. 2) 알코올 의존군에서는 정상 대조군에 비해 Harm Avoidance(HA) 점수와 Self-transcendence(ST)점수는 유의하게 높았으며, Self-directiveness(SD)점수는 유의하게 낮았다. 3) 알코올 의존군 내에서의 각 척도들 간의 상관관계는, HA와 SD 점수, HA와 Persistence(PE) 점수, ST와 SD 점수는 각각 유의한 음의 상관관계, ST와 PE 점수, SD 점수와 Cooperativeness(CO) 점수, Reward Dependence(RD)와 CO 점수는 양의 상관관계를 보였다. 결 론: 이러한 본 연구의 결과는 한국인 남성에서 수줍음을 잘 타며, 걱정도 많고, 염세적이고 쉽게 피로해지는 기질적 특성이 알코올 의존과 연관성이 있음을 의미한다. Objectives : The purpose of this study was to assess the temperament of male parients with alcohol dependence. Methods : The subjects were 30 patients who met DSM-Ⅳ criteria for alcohol dependence and 36 normal controls. All subjects completed Temperament and Character Inventory(TCI) which was developed by Cloninger. Results : 1) The educational level, marital status, and occupation in alcohol dependence group were significantly lower than those of normal control group, but there was no difference in the age between two groups. 2) Among the scores of TCI, the score of harm avoidance(HA) and self-transcendence(ST) were significantly higher in the alcohol dependence group than in the normal control group. 3) In the alcohol dependence group, a significant negative correlation among the scores of TCI was between HA and SD, HA and Persistence(PE), ST and SD, and positive correlation between ST and PE, SD and Cooperativeness(CO), Reward Dependence(RD) and CO. Conclusion : These results suggest that shy, fearful, pessimistic and fatigable temperament are related to developing alcohol dependence in Korean males.

개에서 이환된 장림프관 확장증 2례

송유미,이영원 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2011 動物醫科學硏究誌 Vol.18 No.1

A 2-year-old intact male Rottweiler (Case 1) presented with chronic diarrhea and weight loss. a 4-year-old intact female Yorkshire terrier (Case 2) had the history of chronic ascites. Common clinicopathologic findings were hypoalbuminemia, hypocalcemia and hypoglobuliemia. Abdominal radiographic finding were ascites. On abdominal ultrasonography, intestinal abnormalities including hyperechoic mucosal striation, thickened wall were detected. In case 1, exploratory laparotomy findings were distended lymphatic vessel and white nodular masses in serosa of intestine. On histopathologic examination, dilated lymphatic vessel in mucosa and inflammation in villi were founded. Based on these results, Case 1 was diagnosed definitely as intestinal lymphangiectasia. Based on ultasonographic findings, Case 2 tentatively diagnosed as intestinal lymphangiectasia and inflammatoy bowel disease. At 14 days after surgery, Case 1 was dead because of respiratory sign. At Case 2, ascites is presently being controlled by using prednisolone, antibiotics.

StatXact를 이용한 정확검정

송연재,신미영 가톨릭대학교 자연과학연구소 2002 자연과학논문집 Vol.23 No.-

소표본으로부터 정확한 결과를 이끌어 내어 신뢰성 있는 의사결정을 내릴 수 있게 해주는 정확검정을 위한 통계패키지의 개요를 StatXact 중심으로 알아보고 여러 가지 가능한 정확검정 방법에 대해 비교해 본다. When the sample size is small, one can perform inference using exact distributions rather than large-sample approximations. In this paper, the several statistical packages are compared for exact tests using a real small sample.

PISA 2012 결과에 나타난 성별에 따른 학업성취 영향요인 비교

송미영,임현정,임해미,박혜영,구자옥 이화여자대학교 교육과학연구소 2015 교육과학연구 Vol.46 No.4

The existence of gender gaps in the Programme for International Student Assessment (PISA) scores has been documented in the literature. In particular, it was revealed that on average Korean female students underperform/outperform their male counterparts in mathematics/reading scores for PISA 2012. This study was conducted to examine crucial determinants in understanding gender differences. We examined whether or not the influence of educational contextual variables on mathematics, reading and science achievement differs by gender using multilevel model with each group of male and female students. As a result, there were variables that had more influence on male or female students, though there were some differences by subject. It can be concluded that females have been affected more by teachers than by parents, while males have been affected more by parents. Also, creative extracurricular activities had much more of an effect male students than females. In addition, participation in math-related activities only influenced females, and academic and vocational expectation in math and class management of math teachers only influenced male students. Based on the results, we proposed an educational and political plan that may bridge disparity gaps in academic achievement by gender.

질트리코모나스 (Trichomonas vaginalis)의 항원성 분석에 관한 연구

송준호,임미혜,민득영 한양대학교 의과대학 1991 한양의대 학술지 Vol.11 No.1

Trichomonas vaginalis is a flagellated protozoan parasite which is a major causative organism of vaginitis in women and of urethritis in men. In the present study to elucidate the immune response involving host-parasite interrelationship, antigen analysis of this parasite was carried out using sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), enzyme-linked immunoelec-trotransfer blot (EITB) and enzyme-linked immunosorbent assay (ELISA). For the study sera from 21 Trichomonas vaginalis patients, 7 other parasite-infected patients, 2 candidiasis patients, 17 healthy students and 4 young children under 5 years old were subjected and the results obtained were as follows: 1. In SDS-PAGE, sonicated total antigens from 5 strains of T. vaginalis revealed 20-25 protein profiles ranging 14-110 KDa in molecular weight. 2. On EITB probed with sera from trichomoniasis, immunogenic bands was recognized. But in children the bands of 15, 18 and 23KDa were not seen. 4. In high performance gel filtration chromatography of sonicated total antigen of T. vaginalis, 10 peaks were identified as in ranging 2.6-155 KDa. 5. In ELISA using fractions of 10 peaks from high performance gel filtration chromatography as antigens, values of IgG and IgM antibodies of trichomoniasis patients were significantly higher than those of healthy controls (P〈0.001 or P〈0.001-0.002 respectively). In conclusion with results obtained in the present styudy it is assumed that immunogenic bands in 15, 18and 23KDa on SES-PABE may connote the important significance on immune response in T. vaginalis infection.

개에서 림프병증의 초음파학적 특징에 대한 증례

송유미,이영원 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2011 動物醫科學硏究誌 Vol.18 No.1

The objective of this report was to compare ultrasonographic features of lymphanderopathy of a case in our hospital to result of previous studies with the hope of identifying predictive parameter that differenciate lymphandenopathy. A 2-year-old male mongrel dog's chief complaints was dyspnea from three weeks ago. On physical examination. Swelling of submandibular and prescapular lymph node was founded. Radiography showed increased radioopacity of cranioventral lung field and widened cranial mediastinal lesion with soft tissue opacity on the thoracic views. And ill-defined mass with soft tissue opacity on the mid-abdomen views was detected. On ultrasonography, short/long axis ratio of prescapular lymph node is 0.74. In deep lymph nodes, short/long axis ratio was respectively 0.56, 0.43, 0.67, 0.61. Irregular contour and hyperechoic perinodal fat were common features. This features are coreespond with sonographic features of malignant lymph node of previous study. Based on cytologic results, lymphoma was diagnosed. Ultrasound provides noninvasive, real-time imaging information of both peripheral and more deeply lymph node.

증거기반 평가 설계와 타당도의 통합적 관점에서의 문항 특성 분석 활용

송미영,전경희 이화여자대학교 교육과학연구소 2022 교육과학연구 Vol.53 No.3

본 연구는 학생 평가의 타당화를 위해 증거기반 평가 설계와 타당도의 통합적 관점에서 문항 특성 분석을 활용하는 방안을 탐색하는 데 목적이 있다. 이를 위해 타당도의 고전적 개념을 확장한 통합적 접근을 살펴보고, 문항 특성 분석 기법을 활용하여 평가 계획에서부터 평가 도구 개발, 평가 결과의 분석 및 활용에 이르기까지 학생 평가의 전반적인 운영 과정에서 타당도를 제고하는 방안을 제안하였다. 구체적으로 타당도의 증거 유형별 문항 특성 분석 적용 방안을 제시한 후, 이를 경험적 자료에 적용하여 방법론적 적합성과 유용성을 검증하였다. 이어 학생 평가의 타당도 제고를 위해 증거기반 평가 설계 모형과 문항 특성 분석을 연계하여 활용하는 방안을 탐색하였다. 실제 교육과정 기반의 대규모 평가 자료에 문항 특성 분석을 적용한 결과, 이러한 접근 방법이 문항 특성에 대한 포괄적이고 심층적인 정보를 제공함으로써 학생 평가의 타당도 증거를 강화하기 위한 유용한 분석틀이 될 수 있음을 시사하였다. 이를 통해 문항 특성 분석이 국가 수준 및 시도교육청 단위의 대규모 평가뿐 아니라 단위 학교 평가 맥락에서의 학생 평가 타당화 과정에서 다양하고 종합적인 증거를 수집하는 데 확장성이 큰 방법론으로 활용될 수 있음을 확인하였으며, 이에 따른 교육적 시사점을 논의하고 후속 연구를 제안하였다. This study explored feature analysis (FA) from the perspective of an integrated approach to validity and evidence-centered design. To this end, this study aimed to demonstrate how FA provides validity evidence in the overall operation process of student assessments based on an integrated approach that extends the classical concept of validity. Specifically, the methodological suitability and usefulness of FA were verified by applying the approach to empirical assessment data and presenting data collection procedures for each type of evidence of validity. Next, from the perspective of enhancing the validity of student assessment, ways of linking evidence-centered design with FA were suggested, and methods for applying FA to each stage of the evidence-centered design were explored. The results of applying FA to the 2019 National Assessment of Educational Achievement indicated that FA can be a functional analytic framework for enhancing validity evidence of student assessments by providing comprehensive and in-depth information on item features. Hence, the results of this study suggest that FA can be extended to a highly elaborate approach to collect various and comprehensive evidence in the process of validating student assessments in the context of individual school assessment as well as large-scale assessment at the national and provincial level. Based on such results, educational implications and suggestions for follow-up studies were discussed.

Ionized Calcium 및 Chitosan의 혼합처방에 따른 항균효과에 관한 연구

송명수,김미정,김영일,최동성,양재헌 又石大學校 1998 論文集 Vol.20 No.-

The antibacterial effects of chitosan depend on its molecular weight. The inhibition rate of bacteria growth of designated high in Gram positive, which was high in S aurens, S. epidermidis and Bacillus subtilis, low in S. mutans, high in C. albicans in fungi, low in A. niger. The inhibition rate of bacteria growth of chitosan was comparatively high in Gram positive, low in S. mutans and it showed high numerical value in C. albicans of fungi. The rate recorded good result at molecular weight 200,000 relatively, there was no difference, according to the molecular weight. The inhibition rate of bacteria growth according to the concentration of the increased differently between 1,000~10,000㎍/㎖, it showed antibacterial activity close to the inhibition rate of growth of chitosan rather than ionized calcium. The minimum inhibitory concentration marked the highest in the mixture of cihtosan and ionized calcium for all kind of bacteria generally, there was a little difference between yeast and fungi.