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      • 젊은 성인에서 흡연에 의한 상완동맥 내피기능의 부전에 관한 연구

        이상철,권영주,방덕원,이선해,이보영,김지욱,김영훈,온영근,현민수,김성구 순천향의학연구소 2002 Journal of Soonchunhyang Medical Science Vol.8 No.1

        Background and Objectives : Cigarette smoking is a major factor and the most modifiable risk factor for atherosclerosis. Endothelial dysfunction is an early event in atherosclerosis, before the structural change of the systemic arteries. We hypothesized that endothelial dysfunction might be present in the systemic arteries of young adult smokers and that this might be dose-dependent phenomenon. Therefore, we try to certify that smoking is associated with endothelial dysfunction in healthy young adults without other risk factor of atherosclerosis. Subjects and Methods : we studied noninvasively 29 subjects aged 3 to 4 decades without other risk factor of atherosclerosis, they were composed of the two groups, current smokers(n=15) and nonsmokers(n=14). Smoking history varied from 3 to 20 pack years. Using high-resolution ultrasound, vessel diameter and mean flow rate were measured at rest, during reactive hyperemia(with flow-mediated endothelium-dependent dilation), and after sublingual nitroglycerin(NG-induced endothelium-independent vasodilation). Result : Flow mediated endothelium dependent dilation was observed in the control subjects (9.4±3.44%) but was impaired in the smokers(5.8±2.51%)(p=0.004). NG-induced endothelium independent dilation is no difference in all subjects. Conclusion : Cigarette smoking is associated with endothelial dysfunction in healthy young adults.

      • KCI등재

        미세 전기기계 시스템용 알루미늄 박막의 탄성계수 및 항복강도 평가

        주영창,손동일,관동일 대한금속재료학회(대한금속학회) 2001 대한금속·재료학회지 Vol.39 No.3

        Nowadays, the aluminum films have wide application in micromechanical devices such as micro sensors and actuators, so that their mechanical properties come to be very important for reliability evaluation. However, there is no standardized method to evaluate the mechanical properties of material used in MEMS (micraelectromechanical system) device since the measured mechanical properties are influenced by many factors such as surface condition, friction force, etc. Hence, we intended to evaluate the mechanical properties of thin film in our study, which is important in mechanical operation. Because MEMS devices are usually operating in elastic range, the Young's modules and yield strength were evaluated by using microcantilever beam technique. First, Al cantilever beams were fabricated using the silicon bulk micromachining technology to have various film thickness. And then, the load-displacement curve was obtained by nanoindentation method. The linear relation in elastic range was utilized in deriving the Young's modulus of Al film, which gives us reproducible result regardless of film thickness. In high load range, the deviation from the linear relation was detected, so that the yield strength of Al film could be evaluated. It is found that the yield strength increases with decreasing film thickness. By applying the misfit dislocation theory and the Hall-Petch relation, the theoretical estimation could predict well the trend of yield strength.

      • 만선신부전 환자에서 관상동맥조영술 소견에 관한 연구

        한대희,김성구,박상호,김성한,조원영,방덕원,조윤행,정의룡,은영근,권영구 순천향의학연구소 2003 Journal of Soonchunhyang Medical Science Vol.9 No.1

        Background : Patients with chronic renal fialure have a substantially elevated risk of death from cardiovascular diseases than do the general population. the patients with chronic renal failure are at significantly increased freqeuncy of hypertension, hyperlipidemia, and diabetes mellitus which are known to the risk factors of the coronary artery diseases, and the prevalence of the coronary artery diseases in chronic renal failure patients is highly associated with the hemodynamic disorder and metabolic abnormalities. therefore we expected that the coronary angiographic findings in patients with chronic renal failure should be different from the general population (control groups) and investigated the risk factors contributing to coronary artery diseases. Method : we have retrospectively compared the coronary angiographic findings of 44 patients with chronic renal failure on hemodialysis with that of 88 patients in the general population and investigated the factors contributing to the development and acceleration of coronary artery diseases in patients with chronic renal failure Result : Hypertension and diabetes mellitus which is risk factors for coronary artery disease is significantly increased in patients with chronic renal failure, in coronary angiographic finding the severity of the lesion is worse. the incidence of PCI or CABG of patients with chronic renal failure is more than that of control group but statistically no difference between patients with chronic renal failure and control group. the sex, the duration of disease, the duration of dialysis, serum creatinine in patients with chronic renal failure have no correlation to the prevalence of coronary artery disease and severity of lesion. hyperglycemic patients with chronic renal failure have high incidence of coronary artery disease and are worse in the severity of lesion Conclusions : There is significantly increased the pevalence and severity of involving multiple coronary artery diseses in hyperglycemic patients with CRF.

      • 관동맥 조영술상 관동맥의 심근교 현상에 관한연구

        권영주,목지오 순천향의학연구소 1997 Journal of Soonchunhyang Medical Science Vol.3 No.2

        BACKGROUND: Myocardial bridging is defined as embedment of a segment of the coronary artery into the myocardium so that during ventricular systole the segment of artery is compressed. The prevalance of myocardial bridges among consecutive patients coronary angiography varies between 0.5% and 16% with most studies reporting an incidence of less than 2%. Because any studies is not reported about myocardial bridging in Korea, this study was done to establish the angiographic evidence of myocardial bridging in cineangiograms performed in the cardiac laboratory of the Soonchunhang University PATIENTS AND METHODS: In the 10-years period between 1987 and 1996, selective coronary angiography was performed on 1079 patients at the Medical University of Soonchunhang Hospitals. All studies were reviewed and patients were divided into three groups on the basis of the degree of systolic compression: Mild(1-30% systolic compression). Moderate(31-50% systolic compression), and Severe(51-100% systolic compression). RESULTS: 1. 10 PATIENTS(0.93%) Were found to have myocardial bridge. and 9 patients had systolic compression of the left anterior descending coronary artery and one patient had compression of the right coronary artery. 2. Cineangiograms of all 292 "normal" patients who had symptomes suggestive of angina pectoris were reviewed and 7 patients(2.4%) were found to have myocardial bridging. 3. 4 patients had mild myocardial bridge, 1 patient had moderate, and 5 patients had severe. 4. The ECG was normal in 4 patients, showed left ventricular hypertrophy in 5 patients, and showed atrial fibrillation. Treadmill exercise test was positive in 5 patients, and non-diadnostic test due to insufficient exercise capacity was 5 patients. CONCLUSIONS: The angiographic incidence of myocardial bridges was noted was noted 0.93% and most common site is the left anterior descending artery.

      • KCI등재

        제7차 교육과정에 대응한 중학교 공간구조의 유형별 분류와 특성 고찰

        권영주,김용승 대한건축학회 2004 대한건축학회논문집 Vol.20 No.12

        The 7th educational program based on "demander focus, learner focus, and opened education" requires many changes of school facilities For the purpose of analyzing the characteristics of spatial structure of middle school corresponding to the 7th educational program, 25 numbers of middle schools founded during 2002-2003 in Gyeonggi-do were analyzed as the subject At first, in order to understand the characteristics of spatial structure, 3 types of patterns such as "curriculum classroom, curriculum laboratory, home base" were categorized and it results in more three types of patterns such as "curriculum block, home base breakaway, curriculum laboratory breakaway", and after more objective analysis based on space syntax, the most opened space structure turns out to be "curriculum block type", and the most closed space structure turns out to be "home base breakaway type"

      • 모니터용 회로기판의내구성 향상을 위한 열응력 해석

        權寧住,김진안 홍익대학교 산업기술연구소 2001 産業技術 Vol.11 No.-

        In this paper, the thermal stress analysis of the PCB(printed Circuit Board) of a monitor is carried out for various array types of chips on the printed circuit board and two PCB structural models. The electronic chip on the printed circuit board usually emits heat and this heat generates the thermal stress around the chip. The thermal load due to the heat generation of chips on the printed circuit board may cause the malfunction of the electronic equipment such as monitor, computer etc.. Hence, the PCB should be designed to withstand this thermal load. The thermal stress analysis for the durability of the PCB is done using the finite element analysis code, NISA.

      • 고준위폐기물 처분용기에 대한 구조안전성 평가기준 및 평가방법

        權寧住 弘益大學校 産業技術硏究所 2004 産業技術 Vol.14 No.-

        In this paper, the structural safety evaluation criteria and method for the spent nuclear fuel disposal canister is studied. Since the spent nuclear fuel disposal emits high temperature heats and much radiation, its careful treatment is required. For that, a long term(usually 10,000 years) safe repository for the spent nuclear fuel disposal should be secured. Usually this repository is expected to locate at a depth of 500m underground. The canister construction which is designed for the spent nuclear fuel disposal in a deep repository in the crystalline bedrock is a solid structure with cast iron insert, corrosion resistant overpack and lid and bottom, and entails an evenly distributed load of hydrostatic pressure from underground water and high pressure from swelling of bentonite buffer. Hence, the canister must be designed to withstand these high pressure loads. If many design conditions are not arranged, structural defects which are caused by the hazardous spent nuclear fuel disposal can occur on the canister during storing it. Therefore, various structural analyses must be performed to predict these structural problems. For this, the structural safety evaluation criteria and method for the spent nuclear fuel disposal canister are required.

      • 초고속선의 기계기술 특성

        權寧住 홍익대학교 산업기술연구소 1997 産業技術 Vol.7 No.-

        In this study, we reviewed the classification of the super-high-speed ship whose speed is larger than 50 knots and analyzed its mechanical engineering technology characterstics. It is concluded through this study that the traditional(mono or twin) hull form ship which is operated by buoyant force, lift force or air pressure has the limit in speed and size respectively to become to become the super-high-speed passenger and container ship. On the other hand, this analysis shows that the hybird hull form ship can be the super-high-speed ship. In this type of super-high-speed ship, there are SWASH ship, HYSWAS, LAHHS, HYACS, and SWAACS etc..

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